| 1 | AyurMaya Capital Management Company, LP | +801.0% | +671.5% | 118.7% | 2.20 | −36.7% | 1.43 | +651.9pp | 100% | Open in PORT → |
| 2 | Atlas Merchant Capital LLC | +519.8% | +444.9% | 322.7% | 1.39 | −72.0% | 2.26 | +425.3pp | 66% | Open in PORT → |
| 3 | Founders Fund Growth Management, LLC | +514.6% | +440.6% | 155.7% | 1.77 | −76.4% | 3.74 | +421.0pp | 98% | Open in PORT → |
| 4 | TAKEDA PHARMACEUTICAL CO LTDcorporate treasury? | +393.0% | +340.5% | 75.1% | 2.36 | −30.1% | 1.38 | +320.9pp | 100% | Open in PORT → |
| 5 | TYBOURNE CAPITAL MANAGEMENT (HK) LTD | +392.5% | +340.0% | 66.1% | 2.59 | −30.6% | 1.55 | +320.4pp | 97% | Open in PORT → |
| 6 | V3 Holding Ltdcorporate treasury? | +327.2% | +285.6% | 112.1% | 1.77 | −51.4% | 4.17 | +266.0pp | 100% | Open in PORT → |
| 7 | INSTITUTIONAL VENTURE MANAGEMENT XVI, LLC | +325.1% | +283.8% | 133.0% | 1.59 | −72.5% | 0.50 | +264.2pp | 99% | Open in PORT → |
| 8 | SCF Partners, Inc. | +324.4% | +283.2% | 54.1% | 2.78 | −27.4% | 1.30 | +263.6pp | 99% | Open in PORT → |
| 9 | Vantage Consulting Group Inccorporate treasury? | +324.0% | +282.9% | 97.1% | 1.87 | −57.0% | 2.88 | +263.3pp | 100% | Open in PORT → |
| 10 | Cannae Holdings, Inc. | +313.6% | +274.2% | 1750.0% | 0.91 | −89.5% | 1.68 | +254.6pp | 81% | Open in PORT → |
| 11 | Nextech Invest, Ltd. | +295.0% | +258.5% | 47.8% | 2.94 | −14.1% | 1.13 | +238.9pp | 100% | Open in PORT → |
| 12 | Siguler Guff Advisers, LLC | +288.4% | +252.9% | 405.1% | 0.94 | −59.4% | −1.25 | +233.3pp | 100% | Open in PORT → |
| 13 | BRC Group Holdings, Inc. | +287.5% | +252.1% | 95.8% | 1.79 | −53.8% | 2.72 | +232.5pp | 91% | Open in PORT → |
| 14 | Founders Fund VII Management, LLC | +272.4% | +239.3% | 86.5% | 1.84 | −37.3% | 1.53 | +219.7pp | 100% | Open in PORT → |
| 15 | TCG Crossover Management, LLC | +271.3% | +238.5% | 60.5% | 2.31 | −22.3% | 1.39 | +218.8pp | 100% | Open in PORT → |
| 16 | Caligan Partners LP | +263.8% | +232.1% | 47.0% | 2.81 | −17.6% | 1.18 | +212.5pp | 100% | Open in PORT → |
| 17 | GREAT POINT PARTNERS LLC | +239.8% | +211.7% | 66.0% | 2.03 | −26.7% | 1.37 | +192.1pp | 98% | Open in PORT → |
| 18 | TRV GP V, LLC | +238.8% | +210.9% | 76.5% | 1.83 | −19.2% | 1.28 | +191.3pp | 100% | Open in PORT → |
| 19 | Foresite Capital Management V, LLC | +236.0% | +208.4% | 53.8% | 2.38 | −25.1% | 1.35 | +188.8pp | 92% | Open in PORT → |
| 20 | TRV GP VI, LLC | +234.2% | +206.9% | 58.9% | 2.21 | −20.7% | 1.17 | +187.3pp | 100% | Open in PORT → |
| 21 | Venrock Adviser, LLC | +231.4% | +204.5% | 55.6% | 2.30 | −33.4% | 1.40 | +184.9pp | 91% | Open in PORT → |
| 22 | Elemental Capital Partners LLC | +228.4% | +201.9% | 84.3% | 1.75 | −45.0% | 3.77 | +182.3pp | 91% | Open in PORT → |
| 23 | TRV GP IV, LLC | +226.5% | +200.3% | 114.9% | 1.46 | −59.0% | 1.26 | +180.7pp | 95% | Open in PORT → |
| 24 | Kite Lake Capital Management (UK) LLP | +222.5% | +196.9% | 60.0% | 2.13 | −35.1% | 1.79 | +177.3pp | 99% | Open in PORT → |
| 25 | Alta Partners Management Company, L.P. | +213.7% | +189.4% | 58.6% | 2.12 | −35.0% | 0.61 | +169.8pp | 100% | Open in PORT → |
| 26 | Accel Leaders 4 Associates L.P. | +206.7% | +183.3% | 107.7% | 1.48 | −45.5% | 3.16 | +163.8pp | 100% | Open in PORT → |
| 27 | AJU IB Investment Co., Ltd. | +203.2% | +180.4% | 60.7% | 1.99 | −25.4% | 1.02 | +160.8pp | 88% | Open in PORT → |
| 28 | Foresite Capital Management VI LLC | +200.3% | +177.9% | 46.4% | 2.46 | −26.8% | 1.20 | +158.3pp | 99% | Open in PORT → |
| 29 | Valliance Asset Management Ltd | +195.7% | +173.9% | 71.5% | 1.79 | −41.6% | 3.18 | +154.3pp | 99% | Open in PORT → |
| 30 | Fairmount Funds Management LLC | +192.5% | +171.2% | 81.9% | 1.63 | −46.5% | 1.42 | +151.6pp | 99% | Open in PORT → |
| 31 | Saturn V Capital Management LP | +183.5% | +163.4% | 41.6% | 2.56 | −18.3% | 1.34 | +143.8pp | 97% | Open in PORT → |
| 32 | Boxer Capital Management, LLC | +177.7% | +158.4% | 48.3% | 2.23 | −21.0% | 1.14 | +138.8pp | 95% | Open in PORT → |
| 33 | Octagon Capital Advisors LP | +175.2% | +156.2% | 51.3% | 2.10 | −23.1% | 1.34 | +136.6pp | 93% | Open in PORT → |
| 34 | Central Asset Investments & Management Holdings (HK) Ltd | +171.9% | +153.4% | 55.8% | 1.97 | −36.9% | 2.59 | +133.8pp | 99% | Open in PORT → |
| 35 | NVP ASSOCIATES, LLC | +169.5% | +151.3% | 465.8% | 0.99 | −83.9% | 1.88 | +131.7pp | 100% | Open in PORT → |
| 36 | ADAR1 Capital Management, LLC | +164.7% | +147.1% | 45.1% | 2.23 | −16.0% | 1.13 | +127.5pp | 95% | Open in PORT → |
| 37 | Wasserstein Management, L.P. | +163.4% | +146.0% | 40.6% | 2.45 | −22.8% | 0.29 | +126.4pp | 100% | Open in PORT → |
| 38 | ARCH Venture Management, LLC | +162.6% | +145.3% | 61.2% | 1.78 | −33.9% | 1.62 | +125.7pp | 100% | Open in PORT → |
| 39 | HealthCor Partners Management LP | +162.0% | +144.8% | 247.3% | 1.44 | −66.7% | 0.06 | +125.2pp | 100% | Open in PORT → |
| 40 | Logos Global Management LP | +161.5% | +144.3% | 35.6% | 2.72 | −18.6% | 1.03 | +124.7pp | 90% | Open in PORT → |
| 41 | Skorpios Trust | +158.7% | +141.9% | 63.9% | 1.71 | −37.1% | 0.87 | +122.3pp | 100% | Open in PORT → |
| 42 | JOHNSON & JOHNSON | +157.4% | +140.8% | 40.3% | 2.41 | −17.7% | 1.16 | +121.2pp | 99% | Open in PORT → |
| 43 | OCO Capital Partners, L.P. | +156.0% | +139.6% | 61.1% | 1.75 | −21.6% | 2.80 | +120.0pp | 100% | Open in PORT → |
| 44 | Oxbow Capital Management (HK) Ltd | +156.0% | +139.5% | 62.1% | 1.74 | −41.9% | 2.96 | +120.0pp | 96% | Open in PORT → |
| 45 | Commodore Capital LP | +154.4% | +138.2% | 39.2% | 2.44 | −19.7% | 1.28 | +118.6pp | 97% | Open in PORT → |
| 46 | Vivo Capital, LLC | +154.4% | +138.2% | 41.8% | 2.31 | −29.1% | 1.33 | +118.6pp | 82% | Open in PORT → |
| 47 | AIGH Capital Management LLC | +154.4% | +138.2% | 51.9% | 1.96 | −35.4% | 2.62 | +118.6pp | 91% | Open in PORT → |
| 48 | Glencore plccorporate treasury? | +144.0% | +129.1% | 36.4% | 2.49 | −25.1% | 0.56 | +109.5pp | 100% | Open in PORT → |
| 49 | FINDELL CAPITAL MANAGEMENT LLC | +141.6% | +127.0% | 35.4% | 2.52 | −22.1% | 1.25 | +107.4pp | 98% | Open in PORT → |
| 50 | Affinity Asset Advisors, LLC | +137.3% | +123.3% | 33.1% | 2.62 | −17.6% | 1.11 | +103.6pp | 95% | Open in PORT → |
| 51 | Madison Avenue Partners, LP | +135.1% | +121.4% | 36.3% | 2.40 | −26.1% | 1.65 | +101.8pp | 99% | Open in PORT → |
| 52 | FengHe Fund Management Pte. Ltd. | +133.8% | +120.2% | 40.9% | 2.16 | −23.1% | 2.36 | +100.6pp | 100% | Open in PORT → |
| 53 | Lunate Capital Ltd | +133.7% | +120.1% | 73.6% | 1.41 | −32.9% | 1.19 | +100.5pp | 100% | Open in PORT → |
| 54 | Talos Eurisko Asset Management LP | +133.5% | +119.9% | 43.1% | 2.07 | −28.0% | 2.44 | +100.3pp | 100% | Open in PORT → |
| 55 | Deep Track Capital, LP | +133.5% | +119.9% | 39.0% | 2.24 | −20.7% | 1.01 | +100.3pp | 99% | Open in PORT → |
| 56 | BRIGHTLINE CAPITAL MANAGEMENT, LLC | +131.7% | +118.3% | 43.3% | 2.04 | −15.4% | 2.21 | +98.7pp | 99% | Open in PORT → |
| 57 | Atlas Venture Life Science Advisors, LLC | +131.6% | +118.3% | 51.2% | 1.80 | −31.2% | 1.23 | +98.7pp | 100% | Open in PORT → |
| 58 | Vida Ventures Advisors, LLC | +131.6% | +118.3% | 98.3% | 1.29 | −34.9% | 2.65 | +98.7pp | 96% | Open in PORT → |
| 59 | Frazier Life Sciences Management, L.P. | +130.2% | +117.0% | 39.0% | 2.21 | −24.6% | 1.12 | +97.4pp | 86% | Open in PORT → |
| 60 | Avidity Partners Management LP | +129.7% | +116.6% | 50.7% | 1.79 | −33.0% | 1.02 | +97.0pp | 96% | Open in PORT → |
| 61 | ACORN CAPITAL ADVISORS, LLC | +129.5% | +116.4% | 50.6% | 1.79 | −31.4% | 1.20 | +96.8pp | 95% | Open in PORT → |
| 62 | Lynx1 Capital Management LP | +129.3% | +116.3% | 46.0% | 1.93 | −23.4% | 1.03 | +96.7pp | 77% | Open in PORT → |
| 63 | Maple Rock Capital Partners Inc. | +129.1% | +116.1% | 33.1% | 2.53 | −15.8% | 1.84 | +96.5pp | 98% | Open in PORT → |
| 64 | QVT Financial LP | +129.1% | +116.1% | 29.9% | 2.75 | −10.0% | 1.05 | +96.5pp | 91% | Open in PORT → |
| 65 | Madryn Asset Management, LP | +128.5% | +115.5% | 96.0% | 1.26 | −49.5% | 1.26 | +95.9pp | 100% | Open in PORT → |
| 66 | Analog Century Management LP | +128.4% | +115.4% | 42.6% | 2.04 | −26.7% | 2.39 | +95.8pp | 99% | Open in PORT → |
| 67 | PKO BP BANKOWY Universal Pension Society JSC | +127.3% | +114.5% | 38.3% | 2.21 | −19.0% | 1.94 | +94.9pp | 100% | Open in PORT → |
| 68 | MPM BIOIMPACT LLC | +126.7% | +114.0% | 39.0% | 2.17 | −16.1% | 1.14 | +94.4pp | 97% | Open in PORT → |
| 69 | Ma Investment Partnership, LP | +126.5% | +113.8% | 51.1% | 1.76 | −35.8% | 2.27 | +94.2pp | 100% | Open in PORT → |
| 70 | KINNEY ASSET MANAGEMENT, LLC | +124.6% | +112.1% | 186.8% | 0.87 | −61.6% | 1.30 | +92.5pp | 100% | Open in PORT → |
| 71 | Opaleye Management Inc. | +124.5% | +112.1% | 35.7% | 2.31 | −13.6% | 1.30 | +92.5pp | 93% | Open in PORT → |
| 72 | Paradigm Biocapital Advisors LP | +122.0% | +109.9% | 36.0% | 2.26 | −17.7% | 1.03 | +90.3pp | 98% | Open in PORT → |
| 73 | EcoR1 Capital, LLC | +119.2% | +107.4% | 37.5% | 2.15 | −19.3% | 0.95 | +87.8pp | 95% | Open in PORT → |
| 74 | Patient Square Capital LP | +118.7% | +106.9% | 32.0% | 2.46 | −13.8% | 0.96 | +87.3pp | 98% | Open in PORT → |
| 75 | PERCEPTIVE ADVISORS LLC | +117.3% | +105.7% | 32.6% | 2.40 | −17.7% | 1.13 | +86.1pp | 94% | Open in PORT → |
| 76 | STEMPOINT CAPITAL LP | +117.2% | +105.6% | 36.3% | 2.19 | −21.0% | 1.11 | +86.0pp | 95% | Open in PORT → |
| 77 | Shengqi Capital (Hong Kong) Ltd | +116.8% | +105.3% | 67.1% | 1.42 | −42.7% | 3.07 | +85.7pp | 100% | Open in PORT → |
| 78 | Covalis (Gibraltar) Ltdcorporate treasury? | +116.1% | +104.7% | 47.3% | 1.77 | −31.1% | 1.83 | +85.1pp | 98% | Open in PORT → |
| 79 | ANGELO GORDON & CO., L.P. | +115.7% | +104.3% | 25.7% | 2.94 | −10.7% | 0.82 | +84.7pp | 93% | Open in PORT → |
| 80 | Divisar Capital Management LLC | +115.6% | +104.3% | 39.6% | 2.02 | −20.5% | 2.23 | +84.7pp | 96% | Open in PORT → |
| 81 | ENAVATE SCIENCES GP, LLC | +115.1% | +103.7% | 115.8% | 1.12 | −69.7% | 1.34 | +84.1pp | 100% | Open in PORT → |
| 82 | Exome Asset Management LLC | +114.7% | +103.5% | 29.7% | 2.57 | −13.4% | 1.00 | +83.9pp | 97% | Open in PORT → |
| 83 | Flat Footed LLC | +112.9% | +101.9% | 25.5% | 2.92 | −8.6% | 0.63 | +82.3pp | 96% | Open in PORT → |
| 84 | Juniper Capital Advisors, L.P. | +111.1% | +100.3% | 47.0% | 1.73 | −26.7% | −0.10 | +80.7pp | 100% | Open in PORT → |
| 85 | Aisling Capital Management LP | +111.0% | +100.2% | 43.1% | 1.84 | −20.7% | 1.16 | +80.6pp | 98% | Open in PORT → |
| 86 | Value Aligned Research Advisors, LLC | +109.3% | +98.6% | 57.4% | 1.50 | −34.0% | 2.87 | +79.0pp | 100% | Open in PORT → |
| 87 | ENGINE NO. 1 LLC | +108.4% | +97.9% | 48.4% | 1.67 | −29.3% | 2.34 | +78.3pp | 99% | Open in PORT → |
| 88 | Broad Peak Investment Advisers Pte Ltd | +108.0% | +97.5% | 44.1% | 1.78 | −24.8% | 2.39 | +77.9pp | 100% | Open in PORT → |
| 89 | 5AM Venture Management, LLC | +107.9% | +97.5% | 55.1% | 1.52 | −39.1% | 1.31 | +77.9pp | 93% | Open in PORT → |
| 90 | Andar Capital Management HK Ltd | +107.9% | +97.4% | 57.8% | 1.48 | −35.6% | 3.01 | +77.8pp | 99% | Open in PORT → |
| 91 | TLS Advisors LLC | +107.5% | +97.1% | 50.5% | 1.57 | −10.7% | 0.85 | +77.5pp | 99% | Open in PORT → |
| 92 | Slate Path Capital LP | +106.9% | +96.6% | 30.3% | 2.41 | −15.9% | 1.86 | +77.0pp | 95% | Open in PORT → |
| 93 | ACUTA CAPITAL PARTNERS, LLC | +105.6% | +95.4% | 44.0% | 1.76 | −31.9% | 1.20 | +75.8pp | 89% | Open in PORT → |
| 94 | SR One Capital Management, LP | +105.5% | +95.3% | 92.9% | 1.15 | −46.9% | 1.24 | +75.7pp | 90% | Open in PORT → |
| 95 | Soleus Capital Management, L.P. | +105.3% | +95.1% | 26.8% | 2.66 | −10.5% | 0.95 | +75.5pp | 96% | Open in PORT → |
| 96 | Blue Water Life Science Advisors, LP | +104.8% | +94.7% | 46.1% | 1.69 | −31.2% | 1.64 | +75.1pp | 99% | Open in PORT → |
| 97 | Siren, L.L.C. | +104.6% | +94.5% | 41.7% | 1.82 | −23.1% | 1.24 | +74.9pp | 96% | Open in PORT → |
| 98 | Credit Capital Investments LLC | +104.4% | +94.3% | 33.2% | 2.19 | −21.4% | 1.86 | +74.7pp | 98% | Open in PORT → |
| 99 | New Leaf Venture Partners, L.L.C. | +103.8% | +93.8% | 51.5% | 1.55 | −21.6% | 1.28 | +74.2pp | 94% | Open in PORT → |
| 100 | Pivotal bioVenture Partners Investment Advisor LLC | +103.3% | +93.4% | 63.9% | 1.35 | −39.6% | 1.26 | +73.8pp | 81% | Open in PORT → |
