| 1 | AyurMaya Capital Management Company, LP | +802.7% | +676.8% | 118.9% | 2.20 | −36.7% | 1.43 | +657.4pp | 100% | Open in PORT → |
| 2 | Founders Fund Growth Management, LLC | +526.8% | +453.0% | 156.0% | 1.79 | −76.4% | 3.74 | +433.6pp | 98% | Open in PORT → |
| 3 | Atlas Merchant Capital LLC | +519.8% | +447.3% | 323.3% | 1.39 | −72.0% | 2.26 | +427.9pp | 66% | Open in PORT → |
| 4 | TAKEDA PHARMACEUTICAL CO LTDcorporate treasury? | +397.6% | +346.0% | 75.2% | 2.38 | −30.1% | 1.38 | +326.6pp | 100% | Open in PORT → |
| 5 | TYBOURNE CAPITAL MANAGEMENT (HK) LTD | +393.0% | +342.2% | 66.3% | 2.60 | −30.6% | 1.55 | +322.8pp | 97% | Open in PORT → |
| 6 | INSTITUTIONAL VENTURE MANAGEMENT XVI, LLC | +355.9% | +311.0% | 133.0% | 1.64 | −72.5% | 0.51 | +291.6pp | 99% | Open in PORT → |
| 7 | V3 Holding Ltdcorporate treasury? | +352.9% | +308.6% | 112.1% | 1.82 | −51.4% | 4.17 | +289.2pp | 100% | Open in PORT → |
| 8 | SCF Partners, Inc. | +346.3% | +303.0% | 54.0% | 2.88 | −27.4% | 1.30 | +283.6pp | 99% | Open in PORT → |
| 9 | Vantage Consulting Group Inccorporate treasury? | +345.8% | +302.6% | 97.1% | 1.92 | −54.8% | 2.89 | +283.2pp | 100% | Open in PORT → |
| 10 | Cannae Holdings, Inc. | +311.0% | +273.2% | 1753.3% | 0.91 | −89.5% | 1.69 | +253.8pp | 81% | Open in PORT → |
| 11 | BRC Group Holdings, Inc. | +307.5% | +270.3% | 95.8% | 1.84 | −51.4% | 2.72 | +250.9pp | 90% | Open in PORT → |
| 12 | Nextech Invest, Ltd. | +302.2% | +265.7% | 47.8% | 2.98 | −14.1% | 1.13 | +246.3pp | 100% | Open in PORT → |
| 13 | Founders Fund VII Management, LLC | +286.3% | +252.3% | 86.5% | 1.88 | −37.3% | 1.54 | +232.9pp | 100% | Open in PORT → |
| 14 | Siguler Guff Advisers, LLC | +285.2% | +251.3% | 405.8% | 0.94 | −59.4% | −1.25 | +231.9pp | 100% | Open in PORT → |
| 15 | TCG Crossover Management, LLC | +276.8% | +244.2% | 60.6% | 2.34 | −22.3% | 1.40 | +224.8pp | 100% | Open in PORT → |
| 16 | Elemental Capital Partners LLC | +263.2% | +232.6% | 83.9% | 1.87 | −39.4% | 3.78 | +213.2pp | 91% | Open in PORT → |
| 17 | Caligan Partners LP | +262.5% | +232.0% | 47.1% | 2.81 | −17.6% | 1.18 | +212.7pp | 100% | Open in PORT → |
| 18 | Kite Lake Capital Management (UK) LLP | +249.3% | +220.7% | 59.6% | 2.27 | −29.8% | 1.80 | +201.3pp | 99% | Open in PORT → |
| 19 | GREAT POINT PARTNERS LLC | +240.0% | +212.7% | 67.8% | 2.00 | −26.4% | 1.38 | +193.3pp | 95% | Open in PORT → |
| 20 | Accel Leaders 4 Associates L.P. | +239.6% | +212.4% | 107.5% | 1.58 | −45.5% | 3.17 | +193.0pp | 100% | Open in PORT → |
| 21 | TRV GP V, LLC | +238.2% | +211.2% | 76.7% | 1.83 | −19.2% | 1.28 | +191.8pp | 100% | Open in PORT → |
| 22 | Venrock Adviser, LLC | +238.0% | +211.0% | 55.5% | 2.34 | −32.4% | 1.41 | +191.6pp | 91% | Open in PORT → |
| 23 | Foresite Capital Management V, LLC | +236.8% | +210.0% | 53.9% | 2.39 | −25.1% | 1.35 | +190.6pp | 92% | Open in PORT → |
| 24 | Valliance Asset Management Ltd | +231.5% | +205.5% | 70.8% | 1.96 | −34.5% | 3.19 | +186.1pp | 99% | Open in PORT → |
| 25 | TRV GP IV, LLC | +231.0% | +205.1% | 115.1% | 1.48 | −59.0% | 1.26 | +185.7pp | 95% | Open in PORT → |
| 26 | TRV GP VI, LLC | +230.9% | +205.0% | 59.0% | 2.20 | −20.7% | 1.17 | +185.6pp | 100% | Open in PORT → |
| 27 | Alta Partners Management Company, L.P. | +215.4% | +191.7% | 58.7% | 2.13 | −35.0% | 0.61 | +172.3pp | 100% | Open in PORT → |
| 28 | Fairmount Funds Management LLC | +204.6% | +182.3% | 81.5% | 1.67 | −44.4% | 1.49 | +162.9pp | 95% | Open in PORT → |
| 29 | Foresite Capital Management VI LLC | +201.7% | +179.8% | 46.5% | 2.47 | −26.7% | 1.20 | +160.4pp | 99% | Open in PORT → |
| 30 | AJU IB Investment Co., Ltd. | +200.3% | +178.5% | 60.9% | 1.98 | −25.4% | 1.02 | +159.1pp | 88% | Open in PORT → |
| 31 | Central Asset Investments & Management Holdings (HK) Ltd | +198.5% | +177.0% | 55.2% | 2.15 | −31.3% | 2.60 | +157.6pp | 99% | Open in PORT → |
| 32 | Boxer Capital Management, LLC | +190.5% | +170.1% | 48.7% | 2.31 | −19.9% | 1.15 | +150.7pp | 94% | Open in PORT → |
| 33 | Saturn V Capital Management LP | +189.4% | +169.1% | 41.9% | 2.60 | −18.2% | 1.35 | +149.7pp | 91% | Open in PORT → |
| 34 | Oxbow Capital Management (HK) Ltd | +185.9% | +166.1% | 61.3% | 1.93 | −35.0% | 2.97 | +146.7pp | 96% | Open in PORT → |
| 35 | Octagon Capital Advisors LP | +180.0% | +161.0% | 51.4% | 2.14 | −23.1% | 1.35 | +141.6pp | 92% | Open in PORT → |
| 36 | AIGH Capital Management LLC | +173.8% | +155.6% | 51.5% | 2.11 | −30.4% | 2.63 | +136.2pp | 91% | Open in PORT → |
| 37 | NVP ASSOCIATES, LLC | +169.5% | +151.9% | 466.7% | 1.00 | −83.9% | 1.89 | +132.5pp | 100% | Open in PORT → |
| 38 | Logos Global Management LP | +168.5% | +151.0% | 35.7% | 2.79 | −18.2% | 1.03 | +131.6pp | 89% | Open in PORT → |
| 39 | ADAR1 Capital Management, LLC | +167.0% | +149.7% | 45.5% | 2.24 | −16.1% | 1.13 | +130.3pp | 92% | Open in PORT → |
| 40 | Wasserstein Management, L.P. | +164.1% | +147.2% | 40.7% | 2.46 | −22.8% | 0.29 | +127.8pp | 100% | Open in PORT → |
| 41 | ARCH Venture Management, LLC | +163.3% | +146.4% | 61.3% | 1.79 | −33.9% | 1.62 | +127.0pp | 100% | Open in PORT → |
| 42 | HealthCor Partners Management LP | +162.0% | +145.4% | 247.8% | 1.45 | −66.7% | 0.06 | +126.0pp | 100% | Open in PORT → |
| 43 | JOHNSON & JOHNSON | +161.4% | +144.8% | 40.4% | 2.45 | −17.7% | 1.17 | +125.5pp | 99% | Open in PORT → |
| 44 | Vivo Capital, LLC | +159.0% | +142.7% | 41.8% | 2.36 | −29.1% | 1.33 | +123.3pp | 69% | Open in PORT → |
| 45 | Commodore Capital LP | +159.0% | +142.7% | 39.3% | 2.48 | −19.6% | 1.29 | +123.3pp | 97% | Open in PORT → |
| 46 | Skorpios Trust | +158.0% | +141.9% | 64.0% | 1.71 | −37.1% | 0.87 | +122.5pp | 100% | Open in PORT → |
| 47 | OCO Capital Partners, L.P. | +156.3% | +140.4% | 61.2% | 1.75 | −21.6% | 2.80 | +121.0pp | 100% | Open in PORT → |
| 48 | Ma Investment Partnership, LP | +147.9% | +133.0% | 50.4% | 1.95 | −29.7% | 2.28 | +113.6pp | 100% | Open in PORT → |
| 49 | Talos Eurisko Asset Management LP | +146.6% | +131.9% | 42.8% | 2.21 | −24.0% | 2.44 | +112.5pp | 100% | Open in PORT → |
| 50 | Glencore plccorporate treasury? | +145.5% | +130.9% | 36.5% | 2.51 | −25.1% | 0.56 | +111.5pp | 100% | Open in PORT → |
| 51 | FengHe Fund Management Pte. Ltd. | +144.9% | +130.4% | 40.7% | 2.29 | −19.5% | 2.37 | +111.0pp | 100% | Open in PORT → |
| 52 | Vida Ventures Advisors, LLC | +144.8% | +130.3% | 98.3% | 1.35 | −34.9% | 2.66 | +110.9pp | 96% | Open in PORT → |
| 53 | Affinity Asset Advisors, LLC | +143.3% | +129.0% | 33.4% | 2.68 | −17.7% | 1.12 | +109.6pp | 90% | Open in PORT → |
| 54 | Madison Avenue Partners, LP | +143.2% | +128.9% | 36.2% | 2.50 | −23.6% | 1.66 | +109.5pp | 99% | Open in PORT → |
| 55 | Analog Century Management LP | +141.2% | +127.1% | 42.4% | 2.18 | −22.6% | 2.40 | +107.7pp | 99% | Open in PORT → |
| 56 | FINDELL CAPITAL MANAGEMENT LLC | +139.9% | +126.0% | 38.9% | 2.32 | −21.0% | 1.29 | +106.7pp | 72% | Open in PORT → |
| 57 | PKO BP BANKOWY Universal Pension Society JSC | +138.6% | +124.8% | 38.0% | 2.35 | −17.5% | 1.95 | +105.4pp | 100% | Open in PORT → |
| 58 | Shengqi Capital (Hong Kong) Ltd | +137.9% | +124.2% | 66.6% | 1.55 | −42.7% | 3.08 | +104.8pp | 100% | Open in PORT → |
| 59 | Deep Track Capital, LP | +137.0% | +123.5% | 39.0% | 2.28 | −20.6% | 1.01 | +104.1pp | 98% | Open in PORT → |
| 60 | Maple Rock Capital Partners Inc. | +135.0% | +121.7% | 33.0% | 2.61 | −15.8% | 1.84 | +102.3pp | 98% | Open in PORT → |
| 61 | Atlas Venture Life Science Advisors, LLC | +134.1% | +120.9% | 51.3% | 1.82 | −31.2% | 1.23 | +101.5pp | 100% | Open in PORT → |
| 62 | Lunate Capital Ltd | +134.1% | +120.9% | 73.7% | 1.42 | −32.9% | 1.20 | +101.5pp | 100% | Open in PORT → |
| 63 | Frazier Life Sciences Management, L.P. | +133.8% | +120.7% | 39.3% | 2.24 | −24.7% | 1.13 | +101.3pp | 86% | Open in PORT → |
| 64 | BRIGHTLINE CAPITAL MANAGEMENT, LLC | +133.8% | +120.6% | 43.4% | 2.07 | −15.4% | 2.22 | +101.2pp | 99% | Open in PORT → |
| 65 | QVT Financial LP | +132.8% | +119.8% | 29.9% | 2.81 | −10.0% | 1.05 | +100.4pp | 91% | Open in PORT → |
| 66 | Avidity Partners Management LP | +132.0% | +119.0% | 50.9% | 1.81 | −33.0% | 1.03 | +99.7pp | 96% | Open in PORT → |
| 67 | ACORN CAPITAL ADVISORS, LLC | +131.9% | +119.0% | 50.7% | 1.82 | −31.4% | 1.20 | +99.6pp | 95% | Open in PORT → |
| 68 | Lynx1 Capital Management LP | +130.0% | +117.3% | 46.1% | 1.94 | −23.4% | 1.04 | +97.9pp | 77% | Open in PORT → |
| 69 | MPM BIOIMPACT LLC | +129.0% | +116.4% | 39.1% | 2.20 | −16.1% | 1.14 | +97.0pp | 97% | Open in PORT → |
| 70 | PERCEPTIVE ADVISORS LLC | +128.2% | +115.7% | 34.1% | 2.46 | −18.3% | 1.19 | +96.3pp | 92% | Open in PORT → |
| 71 | 5AM Venture Management, LLC | +127.8% | +115.3% | 54.8% | 1.69 | −39.1% | 1.31 | +95.9pp | 93% | Open in PORT → |
| 72 | Andar Capital Management HK Ltd | +126.6% | +114.3% | 57.3% | 1.64 | −29.8% | 3.02 | +94.9pp | 99% | Open in PORT → |
| 73 | Paradigm Biocapital Advisors LP | +125.6% | +113.4% | 36.1% | 2.31 | −17.7% | 1.04 | +94.0pp | 96% | Open in PORT → |
| 74 | Graticule Asia Macro Advisors LLC | +125.6% | +113.4% | 98.4% | 1.26 | −45.4% | 3.85 | +94.0pp | 96% | Open in PORT → |
| 75 | Divisar Capital Management LLC | +123.8% | +111.9% | 39.5% | 2.12 | −17.5% | 2.23 | +92.5pp | 96% | Open in PORT → |
| 76 | ENGINE NO. 1 LLC | +123.7% | +111.7% | 47.9% | 1.82 | −24.1% | 2.35 | +92.3pp | 99% | Open in PORT → |
| 77 | Value Aligned Research Advisors, LLC | +123.3% | +111.4% | 57.1% | 1.62 | −29.5% | 2.88 | +92.0pp | 100% | Open in PORT → |
| 78 | Patient Square Capital LP | +122.7% | +110.8% | 32.0% | 2.52 | −13.8% | 0.96 | +91.4pp | 98% | Open in PORT → |
| 79 | EcoR1 Capital, LLC | +121.7% | +110.0% | 37.6% | 2.19 | −19.3% | 0.95 | +90.6pp | 94% | Open in PORT → |
| 80 | KINNEY ASSET MANAGEMENT, LLC | +121.7% | +109.9% | 187.2% | 0.87 | −61.6% | 1.30 | +90.5pp | 100% | Open in PORT → |
| 81 | STEMPOINT CAPITAL LP | +121.6% | +109.9% | 36.4% | 2.25 | −20.9% | 1.12 | +90.5pp | 95% | Open in PORT → |
| 82 | Opaleye Management Inc. | +120.6% | +109.0% | 34.9% | 2.31 | −13.4% | 1.31 | +89.6pp | 92% | Open in PORT → |
| 83 | Sanofi | +118.0% | +106.7% | 50.9% | 1.70 | −27.4% | 1.82 | +87.3pp | 100% | Open in PORT → |
| 84 | Juniper Capital Advisors, L.P. | +117.5% | +106.3% | 47.0% | 1.79 | −26.6% | −0.10 | +86.9pp | 100% | Open in PORT → |
| 85 | Exome Asset Management LLC | +116.8% | +105.6% | 29.3% | 2.64 | −13.2% | 1.01 | +86.2pp | 95% | Open in PORT → |
| 86 | Covalis (Gibraltar) Ltdcorporate treasury? | +115.9% | +104.8% | 47.4% | 1.77 | −31.1% | 1.83 | +85.4pp | 98% | Open in PORT → |
| 87 | Pivotal bioVenture Partners Investment Advisor LLC | +115.6% | +104.6% | 63.8% | 1.45 | −39.6% | 1.26 | +85.2pp | 81% | Open in PORT → |
| 88 | Flat Footed LLC | +115.3% | +104.3% | 25.5% | 2.97 | −8.6% | 0.64 | +84.9pp | 96% | Open in PORT → |
| 89 | ACUTA CAPITAL PARTNERS, LLC | +115.1% | +104.1% | 44.3% | 1.85 | −31.9% | 1.22 | +84.7pp | 86% | Open in PORT → |
| 90 | ANGELO GORDON & CO., L.P. | +114.4% | +103.5% | 25.8% | 2.92 | −10.7% | 0.82 | +84.1pp | 93% | Open in PORT → |
| 91 | ENAVATE SCIENCES GP, LLC | +113.7% | +102.9% | 116.0% | 1.12 | −69.7% | 1.34 | +83.5pp | 100% | Open in PORT → |
| 92 | OAKTOP CAPITAL MANAGEMENT II, L.P. | +113.0% | +102.3% | 46.3% | 1.77 | −26.3% | 2.59 | +82.9pp | 99% | Open in PORT → |
| 93 | Credit Capital Investments LLC | +112.4% | +101.8% | 33.0% | 2.32 | −18.7% | 1.87 | +82.4pp | 98% | Open in PORT → |
| 94 | Slate Path Capital LP | +109.7% | +99.4% | 30.3% | 2.46 | −15.6% | 1.87 | +80.0pp | 95% | Open in PORT → |
| 95 | Siren, L.L.C. | +109.6% | +99.3% | 42.8% | 1.84 | −23.7% | 1.27 | +79.9pp | 92% | Open in PORT → |
| 96 | Apis Capital Advisors, LLC | +109.6% | +99.3% | 35.6% | 2.14 | −21.8% | 1.96 | +79.9pp | 94% | Open in PORT → |
| 97 | Aisling Capital Management LP | +109.5% | +99.2% | 43.2% | 1.83 | −20.7% | 1.16 | +79.8pp | 98% | Open in PORT → |
| 98 | Broad Peak Investment Advisers Pte Ltd | +109.2% | +98.9% | 44.2% | 1.80 | −24.8% | 2.39 | +79.5pp | 100% | Open in PORT → |
| 99 | DCF Advisers, LLC | +108.5% | +98.3% | 30.6% | 2.42 | −19.2% | 1.66 | +78.9pp | 99% | Open in PORT → |
| 100 | Galaxy Digital Capital Management GP LLC | +108.1% | +97.9% | 46.0% | 1.73 | −24.2% | 2.55 | +78.5pp | 98% | Open in PORT → |
