JANX US Equity

Janux Therapeutics, Inc.

Nasdaq+ Compare Tear sheet →

Health Care · Pharmaceutical Preparations · CIK 1817713 · FYE 1231

$15.58

+0.62 (+4.14%)

USD · as of 2026-07-30 · marketstack

Switch Ticker

Institutional ownership· 13F filers holding JANX · 2026-Q1 methodology → sources →

189 holders

% of shares outstanding held

98.0%

Shares held (13F)

59,586,437

Reporting holders

189

Active share of register77.0%169 active filers

Index / screened out23.0%20 filers

Reporting holders1892026-Q1

Top-10 concentration60.7%

HHI0.0631

Effective holders15.9

Crowding percentile47.0of 782 same-size names

Top holders

largest 100 of 189 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	RA CAPITAL MANAGEMENT, L.P.	11,189,69311.2M	$156M	18.39%	—
2	BlackRock, Inc.	5,433,2335.4M	$76M	8.93%	ADD 33%
3	JANUS HENDERSON GROUP PLC	4,196,4094.2M	$58M	6.90%	TRIM -22%
4	Prosight Management, LP	3,550,0003.5M	$49M	5.84%	ADD 48%
5	FMR LLC	2,535,7242.5M	$35M	4.17%	TRIM -28%
6	STATE STREET CORP	2,464,0172.5M	$34M	4.05%	TRIM -36%
7	VANGUARD CAPITAL MANAGEMENT LLC	1,811,3651.8M	$25M	2.98%	NEW†
8	TCG Crossover Management, LLC	1,789,6171.8M	$25M	2.94%	—
9	Alyeska Investment Group, L.P.	1,601,0891.6M	$22M	2.63%	ADD 23%
10	WELLINGTON MANAGEMENT GROUP LLP	1,597,6501.6M	$22M	2.63%	—
11	VANGUARD PORTFOLIO MANAGEMENT LLC	1,290,2561.3M	$18M	2.12%	NEW†
12	Deep Track Capital, LP	1,187,2901.2M	$17M	1.95%	ADD 1225%
13	Point72 Asset Management, L.P.	1,156,1401.2M	$16M	1.90%	ADD 20%
14	GEODE CAPITAL MANAGEMENT, LLC	1,146,7241.1M	$16M	1.89%	ADD 3%
15	Balyasny Asset Management L.P.	1,090,1471.1M	$15M	1.79%	ADD 23%
16	Logos Global Management LP	1,000,0001.0M	$14M	1.64%	—
17	ORBIMED ADVISORS LLC	983,600983,600	$14M	1.62%	TRIM -50%
18	Nantahala Capital Management, LLC	809,914809,914	$11M	1.33%	NEW
19	BANK OF AMERICA CORP /DE/	801,646801,646	$11M	1.32%	ADD 9%
20	Irenic Capital Management LP	765,804765,804	$11M	1.26%	NEW
21	Woodline Partners LP	738,032738,032	$10M	1.21%	TRIM -28%
22	MORGAN STANLEY	703,940703,940	$10M	1.16%	ADD 14%
23	Squarepoint Ops LLC	604,000604,000	$8M	0.99%	ADD 54%
24	GOLDMAN SACHS GROUP INC	602,013602,013	$8M	0.99%	TRIM -44%
25	TANG CAPITAL MANAGEMENT LLC	500,000500,000	$7M	0.82%	NEW
26	ALGERT GLOBAL LLC	443,397443,397	$6M	0.73%	ADD 142%
27	MILLENNIUM MANAGEMENT LLC	386,810386,810	$5M	0.64%	ADD 33%
28	Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.	376,496376,496	$5M	0.62%	—
29	Rock Springs Capital Management LP	367,009367,009	$5M	0.60%	ADD 2%
30	HRT FINANCIAL LP	366,699366,699	$5M	0.60%	ADD 477%
31	NORTHERN TRUST CORP	362,180362,180	$5M	0.60%	ADD 6%
32	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	354,328354,328	$5M	0.58%	TRIM -9%
33	CITADEL ADVISORS LLC	352,177352,177	$5M	0.58%	TRIM -68%
34	Man Group plc	342,986342,986	$5M	0.56%	ADD 432%
35	VANGUARD FIDUCIARY TRUST CO	313,648313,648	$4M	0.52%	NEW
36	ADAR1 Capital Management, LLC	298,546298,546	$4M	0.49%	ADD 22%
37	JANE STREET GROUP, LLC	251,740251,740	$3M	0.41%	TRIM -53%
38	Jump Financial, LLC	221,800221,800	$3M	0.36%	ADD 129%
39	UBS Group AG	219,806219,806	$3M	0.36%	TRIM -63%
40	JPMORGAN CHASE & CO	229,268229,268	$3M	0.38%	ADD 34%
41	Qube Research & Technologies Ltd	197,145197,145	$3M	0.32%	TRIM -9%
42	SCHRODER INVESTMENT MANAGEMENT GROUP	195,160195,160	$3M	0.32%	TRIM -27%
43	Allspring Global Investments Holdings, LLC	168,976168,976	$2M	0.28%	NEW
44	BML Capital Management, LLC	154,961154,961	$2M	0.25%	NEW
45	Y-Intercept (Hong Kong) Ltd	139,967139,967	$2M	0.23%	NEW
46	Walleye Capital LLC	130,618130,618	$2M	0.21%	TRIM -60%
47	Rangeley Capital, LLC	122,500122,500	$2M	0.20%	ADD 382%
48	Bank of New York Mellon Corp	119,826119,826	$2M	0.20%	—
49	Connor, Clark & Lunn Investment Management Ltd.	119,376119,376	$2M	0.20%	NEW
50	SUSQUEHANNA INTERNATIONAL GROUP, LLP	119,055119,055	$2M	0.20%	ADD 238%
51	TWO SIGMA INVESTMENTS, LP	116,099116,099	$2M	0.19%	TRIM -75%
52	CAPITAL FUND MANAGEMENT S.A.	115,867115,867	$2M	0.19%	NEW
53	ExodusPoint Capital Management, LP	114,572114,572	$2M	0.19%	TRIM -29%
54	Hudson Bay Capital Management LP	110,000110,000	$2M	0.18%	—
55	READYSTATE ASSET MANAGEMENT LP	109,425109,425	$2M	0.18%	TRIM -88%
56	BNP PARIBAS FINANCIAL MARKETS	105,300105,300	$1M	0.17%	ADD 2565%
57	D. E. Shaw & Co., Inc.	98,39598,395	$1M	0.16%	ADD 201%
58	Nuveen, LLC	97,12097,120	$1M	0.16%	—
59	DIMENSIONAL FUND ADVISORS LP	96,63096,630	$1M	0.16%	TRIM -57%
60	Aquatic Capital Management LLC	93,97493,974	$1M	0.15%	ADD 79%
61	Weiss Asset Management LP	93,14493,144	$1M	0.15%	NEW
62	FRANKLIN RESOURCES INC	90,10190,101	$1M	0.15%	TRIM -77%
63	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	87,75787,757	$1M	0.14%	ADD 16%
64	Swiss National Bank	77,10077,100	$1M	0.13%	—
65	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	76,60176,601	$1M	0.13%	—
66	Rafferty Asset Management, LLC	75,73275,732	$1M	0.12%	TRIM -57%
67	WINTON GROUP Ltd	68,50068,500	$952,150	0.11%	ADD 115%
68	CONGRESS ASSET MANAGEMENT CO	66,86766,867	$929,451	0.11%	ADD 17%
69	Headlands Technologies LLC	61,63361,633	$856,699	0.10%	ADD 9%
70	PRICE T ROWE ASSOCIATES INC /MD/	58,80058,800	$818,000	0.10%	TRIM -92%
71	BARCLAYS PLC	55,98855,988	$778,232	0.09%	TRIM -75%
72	FEDERATED HERMES, INC.	54,20054,200	$753,380	0.09%	ADD 356%
73	RHUMBLINE ADVISERS	52,63752,637	$731,644	0.09%	—
74	Engineers Gate Manager LP	51,82151,821	$720,312	0.09%	ADD 294%
75	Raiffeisen Bank International AG	55,00055,000	$716,650	0.09%	ADD 20%
76	Tidal Investments LLC	51,18951,189	$711,527	0.08%	NEW
77	Tema ETFs LLC	51,18951,189	$711,527	0.08%	ADD 38%
78	HSBC HOLDINGS PLC	51,26351,263	$711,018	0.08%	NEW
79	GSA CAPITAL PARTNERS LLP	50,35150,351	$700,000	0.08%	NEW
80	HighVista Strategies LLC	49,38349,383	$686,424	0.08%	ADD 19%
81	DekaBank Deutsche Girozentrale	49,50049,500	$656,000	0.08%	—
82	Invesco Ltd.	46,92346,923	$652,230	0.08%	ADD 66%
83	Russell Investments Group, Ltd.	42,93842,938	$596,835	0.07%	ADD 104%
84	XTX Topco Ltd	42,81442,814	$595,115	0.07%	TRIM -73%
85	NANO CAP NEW MILLENNIUM GROWTH FUND L P	39,50039,500	$549,050	0.06%	ADD 1480%
86	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	38,87538,875	$540,000	0.06%	—
87	MARTINGALE ASSET MANAGEMENT L P	37,98437,984	$527,978	0.06%	ADD 238%
88	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	37,00137,001	$514,314	0.06%	—
89	DEUTSCHE BANK AG\	36,62036,620	$509,018	0.06%	ADD 14%
90	ALLIANCEBERNSTEIN L.P.	35,59035,590	$491,142	0.06%	—
91	Creative Planning	35,20835,208	$489,391	0.06%	NEW
92	PROFUND ADVISORS LLC	33,77633,776	$469,486	0.06%	TRIM -47%
93	Legal & General Group Plc	33,37933,379	$463,970	0.05%	TRIM -23%
94	SG Americas Securities, LLC	31,53331,533	$438,000	0.05%	TRIM -60%
95	FNY Investment Advisers, LLC	30,71030,710	$426,000	0.05%	ADD 198%
96	AMERICAN CENTURY COMPANIES INC	30,21530,215	$419,989	0.05%	ADD 9%
97	TUDOR INVESTMENT CORP ET AL	29,68929,689	$412,677	0.05%	TRIM -62%
98	Quantinno Capital Management LP	26,06426,064	$362,290	0.04%	ADD 8%
99	MetLife Investment Management, LLC	26,03126,031	$361,831	0.04%	ADD 9%
100	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	25,36425,364	$347,976	0.04%	TRIM -16%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Buyers & sellers2026-Q1 vs 2025-Q4 · 112 bought / 85 sold · net −2,620,320 shares · 2.6d of ADV

Bought112 filers

Shares: 13,328,548
Value: $185M
Opened: 46 · 6,684,548 sh
Days of ADV: 13.3d

Sold85 filers

Shares: 15,948,868
Value: $222M
Closed: 32 · 5,690,753 sh
Days of ADV: 15.9d

Net (all filers) −2,620,320 sh · $36M · −4.2% of the prior register

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

RA CAPITAL MANAGEMENT, L.P.

10.4M

11.2M

$156M

BlackRock, Inc.

2.7M

2.9M

3.4M

3.7M

4.1M

5.4M

$76M

JANUS HENDERSON GROUP PLC

3.6M

4.6M

4.5M

4.7M

5.4M

4.2M

$58M

Prosight Management, LP

330K

690K

854K

865K

2.4M

3.5M

$49M

FMR LLC

8.7M

8.9M

9.1M

3.5M

2.5M

$35M

STATE STREET CORP

1.3M

1.4M

1.9M

3.9M

2.5M

$34M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.8M

$25M

TCG Crossover Management, LLC

—

1.8M

$25M

Alyeska Investment Group, L.P.

345K

409K

259K

425K

1.3M

1.6M

$22M

WELLINGTON MANAGEMENT GROUP LLP

535K

393K

492K

702K

1.6M

$22M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

1.3M

$18M

Deep Track Capital, LP

—

90K

1.2M

$17M

Point72 Asset Management, L.P.

621K

377K

2.1M

1.7M

962K

1.2M

$16M

GEODE CAPITAL MANAGEMENT, LLC

715K

781K

902K

1.1M

$16M

Balyasny Asset Management L.P.

—

10K

—

886K

1.1M

$15M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding divides each quarter's as-filed 13F shares by the SEC cover-page share count dated to that same quarter (split-adjusted), not by today's count — so splits and buybacks don't move the line.

Quarter

Holders

Shares held

% shares out

Value held

2026-Q1

189

59,586,437

98.0%

$828M

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · JANX

Full stake history →

Activists — 13D, active intent

RA CAPITAL MANAGEMENT, L.P.19.9%NEWSCHEDULE 13D/A · Amd 4 · event 2025-03-06SEC →

11,971,377 shares · 4 reporting persons

Large holders — 13G, passive (top 5 of 8 by % of class)

Holder	% of class	Type	As of
JANUS HENDERSON GROUP PLC	6.9%	QII	2026-03-31	SEC →
BlackRock, Inc.	6.7%	QII	2026-06-30	SEC →
Prosight Management, LP	5.3%	Passive	2026-02-03	SEC →

▸Register gapwho owns your peers and not you

13F

Institutional ownership· 13F filers holding JANX · 2026-Q1 methodology → sources →

189 holders

% of shares outstanding held

98.0%

Shares held (13F)

59,586,437

Reporting holders

189

Active share of register77.0%169 active filers

Index / screened out23.0%20 filers

Reporting holders1892026-Q1

Top-10 concentration60.7%

HHI0.0631

Effective holders15.9

Crowding percentile47.0of 782 same-size names

Top holders

largest 100 of 189 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	RA CAPITAL MANAGEMENT, L.P.	11,189,69311.2M	$156M	18.39%	—
2	BlackRock, Inc.	5,433,2335.4M	$76M	8.93%	ADD 33%
3	JANUS HENDERSON GROUP PLC	4,196,4094.2M	$58M	6.90%	TRIM -22%
4	Prosight Management, LP	3,550,0003.5M	$49M	5.84%	ADD 48%
5	FMR LLC	2,535,7242.5M	$35M	4.17%	TRIM -28%
6	STATE STREET CORP	2,464,0172.5M	$34M	4.05%	TRIM -36%
7	VANGUARD CAPITAL MANAGEMENT LLC	1,811,3651.8M	$25M	2.98%	NEW†
8	TCG Crossover Management, LLC	1,789,6171.8M	$25M	2.94%	—
9	Alyeska Investment Group, L.P.	1,601,0891.6M	$22M	2.63%	ADD 23%
10	WELLINGTON MANAGEMENT GROUP LLP	1,597,6501.6M	$22M	2.63%	—
11	VANGUARD PORTFOLIO MANAGEMENT LLC	1,290,2561.3M	$18M	2.12%	NEW†
12	Deep Track Capital, LP	1,187,2901.2M	$17M	1.95%	ADD 1225%
13	Point72 Asset Management, L.P.	1,156,1401.2M	$16M	1.90%	ADD 20%
14	GEODE CAPITAL MANAGEMENT, LLC	1,146,7241.1M	$16M	1.89%	ADD 3%
15	Balyasny Asset Management L.P.	1,090,1471.1M	$15M	1.79%	ADD 23%
16	Logos Global Management LP	1,000,0001.0M	$14M	1.64%	—
17	ORBIMED ADVISORS LLC	983,600983,600	$14M	1.62%	TRIM -50%
18	Nantahala Capital Management, LLC	809,914809,914	$11M	1.33%	NEW
19	BANK OF AMERICA CORP /DE/	801,646801,646	$11M	1.32%	ADD 9%
20	Irenic Capital Management LP	765,804765,804	$11M	1.26%	NEW
21	Woodline Partners LP	738,032738,032	$10M	1.21%	TRIM -28%
22	MORGAN STANLEY	703,940703,940	$10M	1.16%	ADD 14%
23	Squarepoint Ops LLC	604,000604,000	$8M	0.99%	ADD 54%
24	GOLDMAN SACHS GROUP INC	602,013602,013	$8M	0.99%	TRIM -44%
25	TANG CAPITAL MANAGEMENT LLC	500,000500,000	$7M	0.82%	NEW
26	ALGERT GLOBAL LLC	443,397443,397	$6M	0.73%	ADD 142%
27	MILLENNIUM MANAGEMENT LLC	386,810386,810	$5M	0.64%	ADD 33%
28	Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.	376,496376,496	$5M	0.62%	—
29	Rock Springs Capital Management LP	367,009367,009	$5M	0.60%	ADD 2%
30	HRT FINANCIAL LP	366,699366,699	$5M	0.60%	ADD 477%
31	NORTHERN TRUST CORP	362,180362,180	$5M	0.60%	ADD 6%
32	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	354,328354,328	$5M	0.58%	TRIM -9%
33	CITADEL ADVISORS LLC	352,177352,177	$5M	0.58%	TRIM -68%
34	Man Group plc	342,986342,986	$5M	0.56%	ADD 432%
35	VANGUARD FIDUCIARY TRUST CO	313,648313,648	$4M	0.52%	NEW
36	ADAR1 Capital Management, LLC	298,546298,546	$4M	0.49%	ADD 22%
37	JANE STREET GROUP, LLC	251,740251,740	$3M	0.41%	TRIM -53%
38	Jump Financial, LLC	221,800221,800	$3M	0.36%	ADD 129%
39	UBS Group AG	219,806219,806	$3M	0.36%	TRIM -63%
40	JPMORGAN CHASE & CO	229,268229,268	$3M	0.38%	ADD 34%
41	Qube Research & Technologies Ltd	197,145197,145	$3M	0.32%	TRIM -9%
42	SCHRODER INVESTMENT MANAGEMENT GROUP	195,160195,160	$3M	0.32%	TRIM -27%
43	Allspring Global Investments Holdings, LLC	168,976168,976	$2M	0.28%	NEW
44	BML Capital Management, LLC	154,961154,961	$2M	0.25%	NEW
45	Y-Intercept (Hong Kong) Ltd	139,967139,967	$2M	0.23%	NEW
46	Walleye Capital LLC	130,618130,618	$2M	0.21%	TRIM -60%
47	Rangeley Capital, LLC	122,500122,500	$2M	0.20%	ADD 382%
48	Bank of New York Mellon Corp	119,826119,826	$2M	0.20%	—
49	Connor, Clark & Lunn Investment Management Ltd.	119,376119,376	$2M	0.20%	NEW
50	SUSQUEHANNA INTERNATIONAL GROUP, LLP	119,055119,055	$2M	0.20%	ADD 238%
51	TWO SIGMA INVESTMENTS, LP	116,099116,099	$2M	0.19%	TRIM -75%
52	CAPITAL FUND MANAGEMENT S.A.	115,867115,867	$2M	0.19%	NEW
53	ExodusPoint Capital Management, LP	114,572114,572	$2M	0.19%	TRIM -29%
54	Hudson Bay Capital Management LP	110,000110,000	$2M	0.18%	—
55	READYSTATE ASSET MANAGEMENT LP	109,425109,425	$2M	0.18%	TRIM -88%
56	BNP PARIBAS FINANCIAL MARKETS	105,300105,300	$1M	0.17%	ADD 2565%
57	D. E. Shaw & Co., Inc.	98,39598,395	$1M	0.16%	ADD 201%
58	Nuveen, LLC	97,12097,120	$1M	0.16%	—
59	DIMENSIONAL FUND ADVISORS LP	96,63096,630	$1M	0.16%	TRIM -57%
60	Aquatic Capital Management LLC	93,97493,974	$1M	0.15%	ADD 79%
61	Weiss Asset Management LP	93,14493,144	$1M	0.15%	NEW
62	FRANKLIN RESOURCES INC	90,10190,101	$1M	0.15%	TRIM -77%
63	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	87,75787,757	$1M	0.14%	ADD 16%
64	Swiss National Bank	77,10077,100	$1M	0.13%	—
65	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	76,60176,601	$1M	0.13%	—
66	Rafferty Asset Management, LLC	75,73275,732	$1M	0.12%	TRIM -57%
67	WINTON GROUP Ltd	68,50068,500	$952,150	0.11%	ADD 115%
68	CONGRESS ASSET MANAGEMENT CO	66,86766,867	$929,451	0.11%	ADD 17%
69	Headlands Technologies LLC	61,63361,633	$856,699	0.10%	ADD 9%
70	PRICE T ROWE ASSOCIATES INC /MD/	58,80058,800	$818,000	0.10%	TRIM -92%
71	BARCLAYS PLC	55,98855,988	$778,232	0.09%	TRIM -75%
72	FEDERATED HERMES, INC.	54,20054,200	$753,380	0.09%	ADD 356%
73	RHUMBLINE ADVISERS	52,63752,637	$731,644	0.09%	—
74	Engineers Gate Manager LP	51,82151,821	$720,312	0.09%	ADD 294%
75	Raiffeisen Bank International AG	55,00055,000	$716,650	0.09%	ADD 20%
76	Tidal Investments LLC	51,18951,189	$711,527	0.08%	NEW
77	Tema ETFs LLC	51,18951,189	$711,527	0.08%	ADD 38%
78	HSBC HOLDINGS PLC	51,26351,263	$711,018	0.08%	NEW
79	GSA CAPITAL PARTNERS LLP	50,35150,351	$700,000	0.08%	NEW
80	HighVista Strategies LLC	49,38349,383	$686,424	0.08%	ADD 19%
81	DekaBank Deutsche Girozentrale	49,50049,500	$656,000	0.08%	—
82	Invesco Ltd.	46,92346,923	$652,230	0.08%	ADD 66%
83	Russell Investments Group, Ltd.	42,93842,938	$596,835	0.07%	ADD 104%
84	XTX Topco Ltd	42,81442,814	$595,115	0.07%	TRIM -73%
85	NANO CAP NEW MILLENNIUM GROWTH FUND L P	39,50039,500	$549,050	0.06%	ADD 1480%
86	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	38,87538,875	$540,000	0.06%	—
87	MARTINGALE ASSET MANAGEMENT L P	37,98437,984	$527,978	0.06%	ADD 238%
88	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	37,00137,001	$514,314	0.06%	—
89	DEUTSCHE BANK AG\	36,62036,620	$509,018	0.06%	ADD 14%
90	ALLIANCEBERNSTEIN L.P.	35,59035,590	$491,142	0.06%	—
91	Creative Planning	35,20835,208	$489,391	0.06%	NEW
92	PROFUND ADVISORS LLC	33,77633,776	$469,486	0.06%	TRIM -47%
93	Legal & General Group Plc	33,37933,379	$463,970	0.05%	TRIM -23%
94	SG Americas Securities, LLC	31,53331,533	$438,000	0.05%	TRIM -60%
95	FNY Investment Advisers, LLC	30,71030,710	$426,000	0.05%	ADD 198%
96	AMERICAN CENTURY COMPANIES INC	30,21530,215	$419,989	0.05%	ADD 9%
97	TUDOR INVESTMENT CORP ET AL	29,68929,689	$412,677	0.05%	TRIM -62%
98	Quantinno Capital Management LP	26,06426,064	$362,290	0.04%	ADD 8%
99	MetLife Investment Management, LLC	26,03126,031	$361,831	0.04%	ADD 9%
100	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	25,36425,364	$347,976	0.04%	TRIM -16%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Buyers & sellers2026-Q1 vs 2025-Q4 · 112 bought / 85 sold · net −2,620,320 shares · 2.6d of ADV

Bought112 filers

Shares: 13,328,548
Value: $185M
Opened: 46 · 6,684,548 sh
Days of ADV: 13.3d

Sold85 filers

Shares: 15,948,868
Value: $222M
Closed: 32 · 5,690,753 sh
Days of ADV: 15.9d

Net (all filers) −2,620,320 sh · $36M · −4.2% of the prior register

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

RA CAPITAL MANAGEMENT, L.P.

10.4M

11.2M

$156M

BlackRock, Inc.

2.7M

2.9M

3.4M

3.7M

4.1M

5.4M

$76M

JANUS HENDERSON GROUP PLC

3.6M

4.6M

4.5M

4.7M

5.4M

4.2M

$58M

Prosight Management, LP

330K

690K

854K

865K

2.4M

3.5M

$49M

FMR LLC

8.7M

8.9M

9.1M

3.5M

2.5M

$35M

STATE STREET CORP

1.3M

1.4M

1.9M

3.9M

2.5M

$34M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.8M

$25M

TCG Crossover Management, LLC

—

1.8M

$25M

Alyeska Investment Group, L.P.

345K

409K

259K

425K

1.3M

1.6M

$22M

WELLINGTON MANAGEMENT GROUP LLP

535K

393K

492K

702K

1.6M

$22M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

1.3M

$18M

Deep Track Capital, LP

—

90K

1.2M

$17M

Point72 Asset Management, L.P.

621K

377K

2.1M

1.7M

962K

1.2M

$16M

GEODE CAPITAL MANAGEMENT, LLC

715K

781K

902K

1.1M

$16M

Balyasny Asset Management L.P.

—

10K

—

886K

1.1M

$15M

Institutional footprint by quarter

Quarter

Holders

Shares held

% shares out

Value held

2026-Q1

189

59,586,437

98.0%

$828M

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · JANX

Full stake history →

Activists — 13D, active intent

RA CAPITAL MANAGEMENT, L.P.19.9%NEWSCHEDULE 13D/A · Amd 4 · event 2025-03-06SEC →

11,971,377 shares · 4 reporting persons

Large holders — 13G, passive (top 5 of 8 by % of class)

Holder	% of class	Type	As of
JANUS HENDERSON GROUP PLC	6.9%	QII	2026-03-31	SEC →
BlackRock, Inc.	6.7%	QII	2026-06-30	SEC →
Prosight Management, LP	5.3%	Passive	2026-02-03	SEC →

▸Register gapwho owns your peers and not you

13F

JANX US Equity☆

Institutional ownership· 13F filers holding JANX · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · JANX

▸Register gapwho owns your peers and not you

Institutional ownership· 13F filers holding JANX · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · JANX

▸Register gapwho owns your peers and not you

JANX US Equity