CIK 1055951
Long positions in SEC Section 13(f) securities (US-listed stocks, ADRs and ETFs), largest first · Δ vs 2025-Q4. A lagged quarterly snapshot (filed ≤45 days after quarter-end); excludes shorts, options, cash, and shares listed only on non-US exchanges — foreign companies held via a US listing or ADR (e.g. Alibaba, TSMC) ARE included.
As filed = each book applied at its quarter-end (what the reported book did) · As copyable = applied at its statutory 45-day filing deadline (what a 13F follower could have earned).
Computing…
Hypothetical modeled performance constructed with hindsight — not actual results, and not indicative of future results. See the Disclaimer.
| Industry group | Weight | Names |
|---|---|---|
| Pharmaceuticals & Biotechnology | 77.73% | 82 |
| Health Care Equipment & Supplies | 10.31% | 9 |
| Unclassified | 5.14% | 4 |
| Health Care Providers & Services | 3.78% | 5 |
| Technology Hardware & Equipment | 1.66% | 2 |
| Insurance | 1.07% | 2 |
| Life Sciences Tools & Services | 0.31% | 1 |
| # | Ticker | Name | Sector | Weight |
|---|---|---|---|---|
| 1 | EWTX | Edgewise Therapeutics, Inc. | Health Care | 11.06% |
| 2 | ELVN | Enliven Therapeutics, Inc. | Health Care | 7.06% |
| 3 | LLY | ELI LILLY & Co | Health Care | 4.93% |
| 4 | SVA | SINOVAC BIOTECH LTD | Unclassified | 4.17% |
| 5 | BSX | BOSTON SCIENTIFIC CORP | Health Care | 3.38% |
| 6 | SION | Sionna Therapeutics, Inc. | Health Care | 3.20% |
| 7 | AZN | Astrazeneca PLC | Health Care | 2.99% |
| 8 | MBX | MBX Biosciences, Inc. | Health Care | 2.46% |
| 9 | CRVS | Corvus Pharmaceuticals, Inc. | Health Care | 2.37% |
| 10 | ARGX | Argenx SE | Health Care | 2.26% |
101/105 names classified · sector 94.9% of weight · industry 94.9% · mkt cap 86.9%; unclassified names shown, never dropped.
Sector is classified on each name's CURRENT fundamentals, not point-in-time — apparent sector drift can reflect the market re-rating a holding, not a manager trade. 13F is a lagged quarterly snapshot of long positions in US-listed securities only — foreign companies held via a US listing or ADR ARE included, but shares listed only on non-US exchanges (plus shorts, options and cash) are not. Latest quarter: 94.9% of the book is sector-classified (unclassified names shown, never dropped).
Only 25% of book weight classified — the grid is NOT representative of the whole book.
Classified: 24.6% of book weight (24/104 names) · unclassified 75.4%: EWTX, ELVN, SVA, SION, AZN, MBX, CRVS, ARGX, CMPX, GPCR +70 more. Size: cap 70/20/10 bands; style: value/growth composite on our own metrics — not Morningstar's model.
No contribution data for this period.
| # | Security | Shares | Value | Weight | Δ QoQ |
|---|---|---|---|---|---|
| 1 | EWTXEDGEWISE THERAPEUTICS INC | 15,518,492 | $489M | 11.1% | HOLD |
| 2 | ELVNENLIVEN THERAPEUTICS INC | 7,959,538 | $312M | 7.1% | HOLD |
| 3 | LLYELI LILLY & CO | 236,800 | $218M | 4.9% | TRIM −21% |
| 4 | SVASINOVAC BIOTECH LTD | 2,718,735 | $184M | 4.2% | HOLD |
| 5 | BSXBOSTON SCIENTIFIC CORP | 2,382,100 | $149M | 3.4% | HOLD |
| 6 | SIONSIONNA THERAPEUTICS INC | 3,530,702 | $142M | 3.2% | HOLD |
| 7 | AZNASTRAZENECA PLC | 670,200 | $132M | 3.0% | NEW |
| 8 | MBXMBX BIOSCIENCES INC | 3,637,887 | $109M | 2.5% | TRIM −8% |
| 9 | CRVSCORVUS PHARMACEUTICALS INC | 7,165,006 | $105M | 2.4% | HOLD |
| 10 | ARGXARGENX SE | 136,900 | $100M | 2.3% | TRIM −6% |
| 11 | EWEDWARDS LIFESCIENCES CORP | 1,230,600 | $99M | 2.2% | TRIM −33% |
| 12 | ISRGINTUITIVE SURGICAL INC | 208,700 | $96M | 2.2% | TRIM −21% |
| 13 | CMPXCOMPASS THERAPEUTICS INC | 15,219,994 | $81M | 1.8% | HOLD |
| 14 | MRKMERCK & CO INC | 663,400 | $80M | 1.8% | NEW |
| 15 | GPCRSTRUCTURE THERAPEUTICS INC | 1,475,403 | $71M | 1.6% | ADD 27% |
| 16 | AVBPARRIVENT BIOPHARMA INC | 3,027,328 | $70M | 1.6% | HOLD |
| 17 | IRONDISC MEDICINE INC | 1,067,550 | $68M | 1.5% | HOLD |
| 18 | SPRYARS PHARMACEUTICALS INC | 8,288,510 | $67M | 1.5% | HOLD |
| 19 | CGONCG ONCOLOGY INC | 948,267 | $64M | 1.5% | TRIM −37% |
| 20 | XENEXENON PHARMACEUTICALS INC | 1,059,971 | $62M | 1.4% | ADD 137% |
| 21 | SYKSTRYKER CORPORATION | 182,500 | $60M | 1.4% | TRIM −44% |
| 22 | BMYBRISTOL-MYERS SQUIBB CO | 925,000 | $56M | 1.3% | ADD 19% |
| 23 | MLYSMINERALYS THERAPEUTICS INC | 2,052,900 | $56M | 1.3% | ADD 109% |
| 24 | PRAXPRAXIS PRECISION MEDICINES I | 172,500 | $56M | 1.3% | ADD 83% |
| 25 | PFEPFIZER INC | 1,946,500 | $55M | 1.2% | ADD 18% |
| 26 | DYNDYNE THERAPEUTICS INC | 2,917,884 | $53M | 1.2% | ADD 32% |
| 27 | NTRANATERA INC | 262,000 | $52M | 1.2% | TRIM −28% |
| 28 | ABVXABIVAX SA | 465,700 | $52M | 1.2% | ADD 27% |
| 29 | UPBUPSTREAM BIO INC | 5,693,589 | $51M | 1.2% | HOLD |
| 30 | DHRDANAHER CORP DEL | 265,800 | $50M | 1.1% | TRIM −11% |
| 31 | CAICARIS LIFE SCIENCES INC | 2,806,811 | $50M | 1.1% | TRIM −10% |
| 32 | ASNDASCENDIS PHARMA A/S | 181,977 | $42M | 0.9% | ADD 6% |
| 33 | STTKSHATTUCK LABS INC | 6,306,127 | $41M | 0.9% | HOLD |
| 34 | GHGUARDANT HEALTH INC | 435,200 | $40M | 0.9% | NEW |
| 35 | ALNYALNYLAM PHARMACEUTICALS INC | 119,000 | $39M | 0.9% | TRIM −59% |
| 36 | PRLDPRELUDE THERAPEUTICS INC | 10,909,256 | $37M | 0.8% | HOLD |
| 37 | CRNXCRINETICS PHARMACEUTICALS IN | 999,000 | $36M | 0.8% | HOLD |
| 38 | AXSMAXSOME THERAPEUTICS INC. | 213,921 | $36M | 0.8% | TRIM −15% |
| 39 | QUREUNIQURE NV | 2,136,149 | $35M | 0.8% | ADD 190% |
| 40 | ORICORIC PHARMACEUTICALS INC | 2,693,929 | $34M | 0.8% | TRIM −26% |
| 41 | ELVELEVANCE HEALTH INC FORMERLY | 114,700 | $34M | 0.8% | ADD 16% |
| 42 | RLMDRELMADA THERAPEUTICS INC | 4,715,864 | $33M | 0.7% | ADD 81% |
| 43 | FBRXFORTE BIOSCIENCES INC | 1,196,955 | $31M | 0.7% | HOLD |
| 44 | TRVITREVI THERAPEUTICS INC | 2,454,400 | $29M | 0.7% | TRIM −23% |
| 45 | ESPRESPERION THERAPEUTICS INC NE | 10,570,300 | $29M | 0.7% | ADD 77% |
| 46 | NPCENEUROPACE INC | 2,096,527 | $28M | 0.6% | TRIM −13% |
| 47 | RYTMRHYTHM PHARMACEUTICALS INC | 314,100 | $27M | 0.6% | ADD 31% |
| 48 | TMOTHERMO FISHER SCIENTIFIC INC | 46,500 | $23M | 0.5% | HOLD |
| 49 | SNDXSYNDAX PHARMACEUTICALS INC | 962,300 | $22M | 0.5% | NEW |
| 50 | IMAIMAGENEBIO INC | 6,210,899 | $22M | 0.5% | HOLD |
| 51 | BTSGBRIGHTSPRING HEALTH SVCS INC | 497,800 | $21M | 0.5% | HOLD |
| 52 | LXEOLEXEO THERAPEUTICS INC | 3,602,450 | $21M | 0.5% | ADD 70% |
| 53 | STROSUTRO BIOPHARMA INC | 801,144 | $20M | 0.5% | NEW |
| 54 | NKTRNEKTAR THERAPEUTICS | 275,000 | $20M | 0.4% | NEW |
| 55 | HELPCYBIN INC | 3,832,843 | $18M | 0.4% | HOLD |
| 56 | KRYSKRYSTAL BIOTECH INC | 69,100 | $18M | 0.4% | TRIM −42% |
| 57 | PVLAPALVELLA THERAPEUTICS INC | 134,600 | $17M | 0.4% | NEW |
| 58 | CRBPCORBUS PHARMACEUTICALS HLDGS | 1,737,287 | $16M | 0.4% | ADD 9% |
| 59 | URGNUROGEN PHARMA LTD | 875,487 | $16M | 0.4% | HOLD |
| 60 | DFTXDEFINIUM THERAPEUTICS INC COM SHS | 804,000 | $15M | 0.3% | NEW |
| 61 | VERAVERA THERAPEUTICS INC | 369,596 | $15M | 0.3% | ADD 5% |
| 62 | QTTBQ32 BIO INC | 2,252,987 | $14M | 0.3% | HOLD |
| 63 | WHWKWHITEHAWK THERAPEUTICS INC | 4,166,000 | $14M | 0.3% | HOLD |
| 64 | AMGNAMGEN INC | 39,900 | $14M | 0.3% | NEW |
| 65 | ALHCALIGNMENT HEALTHCARE INC | 791,000 | $14M | 0.3% | NEW |
| 66 | EYPTEYEPOINT INC | 1,069,147 | $14M | 0.3% | TRIM −57% |
| 67 | JANXJANUX THERAPEUTICS INC | 983,600 | $14M | 0.3% | TRIM −50% |
| 68 | BCRXBIOCRYST PHARMACEUTICALS INC | 1,425,200 | $14M | 0.3% | TRIM −18% |
| 69 | BCAXBICARA THERAPEUTICS INC | 667,300 | $13M | 0.3% | ADD 219% |
| 70 | BIOABIOAGE LABS INC | 711,811 | $12M | 0.3% | TRIM −10% |
| 71 | COGTCOGENT BIOSCIENCES INC | 322,100 | $12M | 0.3% | TRIM −13% |
| 72 | ALMSALUMIS INC | 548,163 | $12M | 0.3% | TRIM −50% |
| 73 | REGNREGENERON PHARMACEUTICALS | 14,700 | $11M | 0.3% | NEW |
| 74 | CARLCARLSMED INC | 1,252,600 | $11M | 0.3% | HOLD |
| 75 | BIIBBIOGEN INC | 61,600 | $11M | 0.3% | NEW |
| 76 | KNSAKINIKSA PHARMACEUTICALS INTL | 180,599 | $9M | 0.2% | TRIM −4% |
| 77 | KROSKEROS THERAPEUTICS INC | 759,155 | $8M | 0.2% | TRIM −6% |
| 78 | GILDGILEAD SCIENCES INC | 59,600 | $8M | 0.2% | NEW |
| 79 | HRTXHERON THERAPEUTICS INC | 9,816,940 | $8M | 0.2% | NEW |
| 80 | AVTXAVALO THERAPEUTICS INC | 475,165 | $7M | 0.2% | TRIM −60% |
| 81 | TECXTECTONIC THERAPEUTIC INC | 226,600 | $7M | 0.2% | TRIM −61% |
| 82 | ACETADICET BIO INC | 1,027,944 | $7M | 0.2% | HOLD |
| 83 | CMPSCOMPASS PATHWAYS PLC | 1,150,646 | $6M | 0.1% | NEW |
| 84 | PHVSPHARVARIS N V | 205,400 | $6M | 0.1% | HOLD |
| 85 | ALXOALX ONCOLOGY HLDGS INC | 2,866,256 | $6M | 0.1% | NEW |
| 86 | AORTARTIVION INC | 151,000 | $6M | 0.1% | NEW |
| 87 | NSPRINSPIREMD INC | 3,133,405 | $5M | 0.1% | HOLD |
| 88 | RVMDREVOLUTION MEDICINES INC | 52,000 | $5M | 0.1% | ADD 101% |
| 89 | ADCTADC THERAPEUTICS SA | 1,318,026 | $5M | 0.1% | TRIM −77% |
| 90 | PTGXPROTAGONIST THERAPEUTICS INC | 42,100 | $4M | 0.1% | ADD 94% |
| 91 | PALIPALISADE BIO INC | 2,333,000 | $4M | 0.1% | ADD 25% |
| 92 | ANROALTO NEUROSCIENCE INC | 167,500 | $4M | 0.1% | ADD 34% |
| 93 | SVRASAVARA INC | 635,000 | $3M | 0.1% | NEW |
| 94 | CGEMCULLINAN THERAPEUTICS INC | 243,006 | $3M | 0.1% | TRIM −10% |
| 95 | PTCTPTC THERAPEUTICS INC | 49,100 | $3M | 0.1% | ADD 112% |
| 96 | LFSTLIFESTANCE HEALTH GROUP INC | 500,000 | $3M | 0.1% | NEW |
| 97 | DRUGBRIGHT MINDS BIOSCIENCES INC | 40,000 | $3M | 0.1% | NEW |
| 98 | JBIOJADE BIOSCIENCES INC | 185,011 | $3M | 0.1% | TRIM −65% |
| 99 | CCCCC4 THERAPEUTICS INC | 856,353 | $2M | 0.1% | TRIM −39% |
| 100 | RCELAVITA MEDICAL INC | 544,895 | $2M | 0.0% | NEW |
| 101 | KALVISTA PHARMACEUTICALS INC | 94,400 | $2M | 0.0% | TRIM −75% |
| 102 | IMAIMAGENEBIO INC | 378,556 | $2M | 0.0% | HOLD |
| 103 | VTGNVISTAGEN THERAPEUTICS INC | 3,060,000 | $2M | 0.0% | HOLD |
| 104 | ATAIATAIBECKLEY INC | 347,000 | $1M | 0.0% | NEW |
| 105 | TRAWTRAWS PHARMA INC | 605,531 | $1M | 0.0% | HOLD |
| Security | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| EWTXEDGEWISE THERAPEUTICS INC | 15.0M | 15.0M | 15.5M | 15.5M | 15.5M | 15.5M | $489M |
| ELVNENLIVEN THERAPEUTICS INC | 8.0M | 8.0M | 8.0M | 8.0M | 8.0M | 8.0M | $312M |
| LLYELI LILLY & CO | 338K | 338K | 338K | 301K | 301K | 237K | $218M |
| SVASINOVAC BIOTECH LTD | 2.7M | 2.7M | 2.7M | 2.7M | 2.7M | 2.7M | $184M |
| BSXBOSTON SCIENTIFIC CORP | 3.2M | 2.8M | 2.8M | 2.4M | 2.4M | 2.4M | $149M |
| SIONSIONNA THERAPEUTICS INC | — | 3.7M | 3.7M | 3.7M | 3.6M | 3.5M | $142M |
| AZNASTRAZENECA PLC | — | — | — | — | — | 670K | $132M |
| MBXMBX BIOSCIENCES INC | 3.8M | 4.0M | 4.0M | 4.0M | 3.9M | 3.6M | $109M |
| CRVSCORVUS PHARMACEUTICALS INC | 6.9M | 6.9M | 7.2M | 7.2M | 7.2M | 7.2M | $105M |
| ARGXARGENX SE | 190K | 207K | 208K | 172K | 146K | 137K | $100M |
| EWEDWARDS LIFESCIENCES CORP | 1.1M | 1.5M | 1.7M | 1.7M | 1.8M | 1.2M | $99M |
| ISRGINTUITIVE SURGICAL INC | 402K | 291K | 291K | 287K | 263K | 209K | $96M |
| CMPXCOMPASS THERAPEUTICS INC | 22.4M | 22.4M | 15.2M | 15.2M | 15.2M | 15.2M | $81M |
| MRKMERCK & CO INC | 830K | — | — | — | — | 663K | $80M |
| GPCRSTRUCTURE THERAPEUTICS INC | 652K | 652K | 1.2M | 1.1M | 1.2M | 1.5M | $71M |
Shares reported each quarter by the largest current holdings. Green = added vs the prior filing of that name, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
