CIK 1346824
Long positions in SEC Section 13(f) securities (US-listed stocks, ADRs and ETFs), largest first · Δ vs 2025-Q4. A lagged quarterly snapshot (filed ≤45 days after quarter-end); excludes shorts, options, cash, and shares listed only on non-US exchanges — foreign companies held via a US listing or ADR (e.g. Alibaba, TSMC) ARE included.
As filed = each book applied at its quarter-end (what the reported book did) · As copyable = applied at its statutory 45-day filing deadline (what a 13F follower could have earned).
Computing…
Hypothetical modeled performance constructed with hindsight — not actual results, and not indicative of future results. See the Disclaimer.
| Industry group | Weight | Names |
|---|---|---|
| Pharmaceuticals & Biotechnology | 92.09% | 72 |
| Unclassified | 4.69% | 6 |
| Health Care Equipment & Supplies | 2.56% | 3 |
| Health Care Providers & Services | 0.38% | 2 |
| Software & IT Services | 0.28% | 2 |
| # | Ticker | Name | Sector | Weight |
|---|---|---|---|---|
| 1 | ASND | Ascendis Pharma A/S | Health Care | 24.92% |
| 2 | PCVX | Vaxcyte, Inc. | Health Care | 7.07% |
| 3 | RYTM | RHYTHM PHARMACEUTICALS, INC. | Health Care | 6.14% |
| 4 | TYRA | Tyra Biosciences, Inc. | Health Care | 4.95% |
| 5 | SION | Sionna Therapeutics, Inc. | Health Care | 4.21% |
| 6 | EWTX | Edgewise Therapeutics, Inc. | Health Care | 3.48% |
| 7 | NAMS | NEWAMSTERDAM PHARMA COMPANY | Unclassified | 3.24% |
| 8 | NUVL | Nuvalent, Inc. | Health Care | 2.75% |
| 9 | DNTH | Dianthus Therapeutics, Inc. /DE/ | Health Care | 2.32% |
| 10 | MLYS | Mineralys Therapeutics, Inc. | Health Care | 2.21% |
79/85 names classified · sector 95.3% of weight · industry 95.3% · mkt cap 69.9%; unclassified names shown, never dropped.
Sector is classified on each name's CURRENT fundamentals, not point-in-time — apparent sector drift can reflect the market re-rating a holding, not a manager trade. 13F is a lagged quarterly snapshot of long positions in US-listed securities only — foreign companies held via a US listing or ADR ARE included, but shares listed only on non-US exchanges (plus shorts, options and cash) are not. Latest quarter: 95.3% of the book is sector-classified (unclassified names shown, never dropped).
Only 2% of book weight classified — the grid is NOT representative of the whole book.
Classified: 1.9% of book weight (3/85 names) · unclassified 98.1%: ASND, PCVX, RYTM, TYRA, SION, EWTX, NAMS, NUVL, DNTH, MLYS +72 more. Size: cap 70/20/10 bands; style: value/growth composite on our own metrics — not Morningstar's model.
No contribution data for this period.
| # | Security | Shares | Value | Weight | Δ QoQ |
|---|---|---|---|---|---|
| 1 | ASNDASCENDIS PHARMA A/S | 10,281,496 | $2.4B | 24.9% | HOLD |
| 2 | PCVXVAXCYTE INC | 11,474,599 | $667M | 7.1% | ADD 7% |
| 3 | RYTMRHYTHM PHARMACEUTICALS INC | 6,666,837 | $580M | 6.1% | HOLD |
| 4 | TYRATYRA BIOSCIENCES INC | 12,198,625 | $467M | 5.0% | HOLD |
| 5 | SIONSIONNA THERAPEUTICS INC | 9,905,045 | $397M | 4.2% | HOLD |
| 6 | EWTXEDGEWISE THERAPEUTICS INC | 10,428,437 | $328M | 3.5% | HOLD |
| 7 | NAMSNEWAMSTERDAM PHARMA COMPANY | 9,550,191 | $306M | 3.2% | HOLD |
| 8 | NUVLNUVALENT INC | 2,534,145 | $260M | 2.8% | ADD 35% |
| 9 | DNTHDIANTHUS THERAPEUTICS INC | 2,611,733 | $219M | 2.3% | ADD 62% |
| 10 | MLYSMINERALYS THERAPEUTICS INC | 7,692,750 | $208M | 2.2% | ADD 5% |
| 11 | SGPSPYGLASS PHARMA INC | 8,021,117 | $208M | 2.2% | NEW |
| 12 | WVEWAVE LIFE SCIENCES LTD | 26,975,505 | $196M | 2.1% | ADD 48% |
| 13 | SEPNSEPTERNA INC | 6,995,858 | $168M | 1.8% | HOLD |
| 14 | IRONDISC MEDICINE INC | 2,450,221 | $157M | 1.7% | ADD 24% |
| 15 | JANXJANUX THERAPEUTICS INC | 11,189,693 | $156M | 1.6% | HOLD |
| 16 | BCRXBIOCRYST PHARMACEUTICALS INC | 15,827,186 | $151M | 1.6% | HOLD |
| 17 | BCAXBICARA THERAPEUTICS INC | 7,255,993 | $144M | 1.5% | ADD 4% |
| 18 | PRAXPRAXIS PRECISION MEDICINES I | 373,787 | $120M | 1.3% | HOLD |
| 19 | GHRSGH RESEARCH PLC | 7,676,697 | $108M | 1.1% | HOLD |
| 20 | ZLABZAI LAB LTD | 5,707,262 | $107M | 1.1% | NEW |
| 21 | TSHATAYSHA GENE THERAPIES INC | 23,555,648 | $105M | 1.1% | HOLD |
| 22 | VORVOR BIOPHARMA INC | 5,404,998 | $96M | 1.0% | HOLD |
| 23 | GERNGERON CORP | 63,771,366 | $95M | 1.0% | HOLD |
| 24 | SPRYARS PHARMACEUTICALS INC | 10,860,977 | $87M | 0.9% | HOLD |
| 25 | SRPTSAREPTA THERAPEUTICS INC | 3,902,596 | $85M | 0.9% | NEW |
| 26 | SYRESPYRE THERAPEUTICS INC | 1,621,620 | $82M | 0.9% | HOLD |
| 27 | EVMNEVOMMUNE INC | 3,494,638 | $80M | 0.9% | HOLD |
| 28 | CLYMCLIMB BIO INC | 11,300,939 | $77M | 0.8% | HOLD |
| 29 | SLDBSOLID BIOSCIENCES INC | 9,339,978 | $67M | 0.7% | ADD 61% |
| 30 | ARTVARTIVA BIOTHERAPEUTICS INC | 9,853,302 | $63M | 0.7% | HOLD |
| 31 | DMRADAMORA THERAPEUTICS INC | 2,399,310 | $62M | 0.7% | NEW |
| 32 | XNCRXENCOR INC | 4,897,237 | $59M | 0.6% | NEW |
| 33 | LBRXLB PHARMACEUTICALS INC | 2,208,604 | $54M | 0.6% | HOLD |
| 34 | JBIOJADE BIOSCIENCES INC | 3,671,083 | $52M | 0.5% | HOLD |
| 35 | ABOSACUMEN PHARMACEUTICALS INC | 20,992,669 | $50M | 0.5% | ADD 41% |
| 36 | FDMT4D MOLECULAR THERAPEUTICS IN | 5,049,779 | $47M | 0.5% | TRIM −11% |
| 37 | FULCFULCRUM THERAPEUTICS INC | 6,053,960 | $46M | 0.5% | HOLD |
| 38 | CAPRCAPRICOR THERAPEUTICS INC | 1,507,844 | $46M | 0.5% | HOLD |
| 39 | IPSCCENTURY THERAPEUTICS INC | 17,754,430 | $40M | 0.4% | NEW |
| 40 | OLMAOLEMA PHARMACEUTICALS INC | 2,600,000 | $39M | 0.4% | HOLD |
| 41 | LENZLENZ THERAPEUTICS INC | 4,178,823 | $38M | 0.4% | HOLD |
| 42 | MNPRMONOPAR THERAPEUTICS INC | 667,207 | $37M | 0.4% | HOLD |
| 43 | PEPGPEPGEN INC | 20,064,545 | $36M | 0.4% | HOLD |
| 44 | DSGNDESIGN THERAPEUTICS INC | 2,972,973 | $32M | 0.3% | ADD 103% |
| 45 | MIRMMIRUM PHARMACEUTICALS INC | 318,554 | $29M | 0.3% | NEW |
| 46 | BIOABIOAGE LABS INC | 1,650,648 | $29M | 0.3% | NEW |
| 47 | LXEOLEXEO THERAPEUTICS INC | 5,000,000 | $29M | 0.3% | HOLD |
| 48 | ASMBASSEMBLY BIOSCIENCES INC | 1,020,410 | $28M | 0.3% | HOLD |
| 49 | RZLTREZOLUTE INC | 9,180,000 | $28M | 0.3% | HOLD |
| 50 | AKTSAKTIS ONCOLOGY INC | 1,503,084 | $27M | 0.3% | NEW |
| 51 | ALXOALX ONCOLOGY HLDGS INC | 13,011,849 | $26M | 0.3% | NEW |
| 52 | ACRSACLARIS THERAPEUTICS INC | 6,804,072 | $26M | 0.3% | NEW |
| 53 | OVIDOVID THERAPEUTICS INC | 10,714,000 | $24M | 0.3% | HOLD |
| 54 | NKTXNKARTA INC | 10,805,129 | $23M | 0.2% | HOLD |
| 55 | TVTXTRAVERE THERAPEUTICS INC | 746,841 | $22M | 0.2% | NEW |
| 56 | GRALGRAIL INC | 428,266 | $22M | 0.2% | HOLD |
| 57 | CCCCC4 THERAPEUTICS INC | 8,000,000 | $21M | 0.2% | HOLD |
| 58 | RLMDRELMADA THERAPEUTICS INC | 2,947,369 | $21M | 0.2% | NEW |
| 59 | BNTCBENITEC BIOPHARMA INC | 1,850,000 | $20M | 0.2% | HOLD |
| 60 | DRUGBRIGHT MINDS BIOSCIENCES INC | 265,000 | $19M | 0.2% | NEW |
| 61 | STROSUTRO BIOPHARMA INC | 715,307 | $18M | 0.2% | NEW |
| 62 | CTNMCONTINEUM THERAPEUTICS INC | 1,296,012 | $17M | 0.2% | TRIM −41% |
| 63 | SABSSAB BIOTHERAPEUTICS INC | 4,401,500 | $17M | 0.2% | HOLD |
| 64 | INSPINSPIRE MED SYS INC | 325,663 | $17M | 0.2% | ADD 129% |
| 65 | AVRANTERIS TECHNOLOGIES GLOBAL | 3,000,000 | $17M | 0.2% | NEW |
| 66 | OKURONKURE THERAPEUTICS INC | 3,998,333 | $17M | 0.2% | NEW |
| 67 | HNGEHINGE HEALTH INC | 364,613 | $14M | 0.1% | ADD 355% |
| 68 | WGSGENEDX HOLDINGS CORP | 209,887 | $13M | 0.1% | ADD 262% |
| 69 | WAYWAYSTAR HLDG CORP | 529,400 | $13M | 0.1% | ADD 267% |
| 70 | HLXCHELIX ACQUISITION CORP III | 1,250,000 | $13M | 0.1% | NEW |
| 71 | PALIPALISADE BIO INC | 7,124,116 | $12M | 0.1% | HOLD |
| 72 | ACRVACRIVON THERAPEUTICS INC | 8,340,508 | $12M | 0.1% | HOLD |
| 73 | RNAATRIUM THERAPEUTICS INC | 864,102 | $12M | 0.1% | NEW |
| 74 | KPTIKARYOPHARM THERAPEUTICS INC | 1,917,354 | $11M | 0.1% | NEW |
| 75 | AVTXAVALO THERAPEUTICS INC | 662,968 | $10M | 0.1% | HOLD |
| 76 | PCSCPERCEPTIVE CAP SOLUTIONS COR | 750,000 | $8M | 0.1% | HOLD |
| 77 | ACETADICET BIO INC | 1,182,624 | $8M | 0.1% | ADD 25% |
| 78 | NAMSWNEWAMSTERDAM PHARMA CO NV-27 | 333,333 | $7M | 0.1% | HOLD |
| 79 | CRVSCORVUS PHARMACEUTICALS INC | 450,000 | $7M | 0.1% | NEW |
| 80 | RANIRANI THERAPEUTICS HLDGS INC | 8,500,000 | $6M | 0.1% | HOLD |
| 81 | EQEQUILLIUM INC | 3,096,336 | $6M | 0.1% | NEW |
| 82 | HOWLWEREWOLF THERAPEUTICS INC | 6,681,307 | $6M | 0.1% | HOLD |
| 83 | MGNXMACROGENICS INC | 1,864,176 | $5M | 0.1% | NEW |
| 84 | MPLTMAPLIGHT THERAPEUTICS INC | 248,294 | $5M | 0.1% | NEW |
| 85 | PTNPALATIN TECHNOLOGIES INC | 70,000 | $1M | 0.0% | HOLD |
| Security | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| ASNDASCENDIS PHARMA A/S | 10.1M | 10.3M | 10.3M | 10.3M | 10.3M | 10.3M | $2.4B |
| PCVXVAXCYTE INC | 8.7M | 12.2M | 12.0M | 12.0M | 10.7M | 11.5M | $667M |
| RYTMRHYTHM PHARMACEUTICALS INC | 6.1M | 6.1M | 5.6M | 5.7M | 6.7M | 6.7M | $580M |
| TYRATYRA BIOSCIENCES INC | 10.6M | 10.6M | 12.2M | 12.2M | 12.2M | 12.2M | $467M |
| SIONSIONNA THERAPEUTICS INC | — | 10.4M | 10.4M | 10.4M | 9.9M | 9.9M | $397M |
| EWTXEDGEWISE THERAPEUTICS INC | 8.9M | 8.9M | 9.9M | 10.4M | 10.4M | 10.4M | $328M |
| NAMSNEWAMSTERDAM PHARMA COMPANY | 8.8M | 10.1M | 10.1M | 10.1M | 9.6M | 9.6M | $306M |
| NUVLNUVALENT INC | — | — | — | 1.2M | 1.9M | 2.5M | $260M |
| DNTHDIANTHUS THERAPEUTICS INC | 1.9M | 2.9M | 2.9M | 2.9M | 1.6M | 2.6M | $219M |
| MLYSMINERALYS THERAPEUTICS INC | 4.9M | 6.1M | 6.1M | 7.3M | 7.3M | 7.7M | $208M |
| SGPSPYGLASS PHARMA INC | — | — | — | — | — | 8.0M | $208M |
| WVEWAVE LIFE SCIENCES LTD | 18.2M | 18.2M | 18.2M | 18.2M | 18.2M | 27.0M | $196M |
| SEPNSEPTERNA INC | 7.0M | 7.0M | 7.0M | 7.0M | 7.0M | 7.0M | $168M |
| IRONDISC MEDICINE INC | — | 1.6M | 1.6M | 1.6M | 2.0M | 2.5M | $157M |
| JANXJANUX THERAPEUTICS INC | 10.4M | 11.2M | 11.2M | 11.2M | 11.2M | 11.2M | $156M |
Shares reported each quarter by the largest current holdings. Green = added vs the prior filing of that name, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
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