$5.32
-0.08 (-1.48%)
USD · as of 2026-08-21 · marketstack
Institutional 13F holdings sum to 107.2% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 14,152,914 shares (settlement 2026-05-15) accounts for the excess.
| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | SUVRETTA CAPITAL MANAGEMENT, LLC | 8,296,3758.3M | $107M | 9.94% | ADD 6% |
| 2 | Cormorant Asset Management, LP | 8,265,0008.3M | $107M | 9.91% | — |
| 3 | BlackRock, Inc. | 7,177,3377.2M | $93M | 8.60% | ADD 6% |
| 4 | FEDERATED HERMES, INC. | 5,669,5895.7M | $73M | 6.80% | TRIM -6% |
| 5 | FRANKLIN RESOURCES INC | 5,048,5985.0M | $65M | 6.05% | — |
| 6 | JANUS HENDERSON GROUP PLC | 3,601,1683.6M | $46M | 4.32% | ADD 23% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 3,559,5693.6M | $46M | 4.27% | NEW† |
| 8 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,300,0003.3M | $43M | 3.96% | TRIM -30% |
| 9 | Paradigm Biocapital Advisors LP | 3,142,4373.1M | $41M | 3.77% | TRIM -15% |
| 10 | Commodore Capital LP | 2,825,0002.8M | $36M | 3.39% | NEW† |
| 11 | STATE STREET CORP | 2,097,2022.1M | $27M | 2.51% | ADD 14% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 1,983,6652.0M | $26M | 2.38% | ADD 4% |
| 13 | CITADEL ADVISORS LLC | 1,905,8751.9M | $25M | 2.28% | NEW† |
| 14 | Aberdeen Group plc | 1,738,3781.7M | $22M | 2.08% | ADD 8% |
| 15 | STEMPOINT CAPITAL LP | 1,621,5281.6M | $21M | 1.94% | ADD 358% |
| 16 | Balyasny Asset Management L.P. | 1,438,7371.4M | $19M | 1.72% | ADD 142% |
| 17 | Parkman Healthcare Partners LLC | 1,354,8001.4M | $17M | 1.62% | ADD 25% |
| 18 | EVENTIDE ASSET MANAGEMENT, LLC | 1,245,5831.2M | $16M | 1.49% | NEW |
| 19 | MORGAN STANLEY | 1,096,1091.1M | $14M | 1.31% | ADD 390% |
| 20 | Essex Woodlands Management, Inc. | 1,084,8571.1M | $14M | 1.30% | — |
| 21 | ORBIMED ADVISORS LLC | 1,069,1471.1M | $14M | 1.28% | TRIM -57% |
| 22 | 5AM Venture Management, LLC | 1,050,0001.1M | $14M | 1.26% | — |
| 23 | Rosalind Advisors, Inc. | 1,036,7371.0M | $13M | 1.24% | ADD 50% |
| 24 | Blue Owl Capital Holdings LP | 912,594912,594 | $12M | 1.09% | ADD 132% |
| 25 | HSBC HOLDINGS PLC | 833,455833,455 | $11M | 1.00% | NEW |
| 26 | Patient Square Capital LP | 795,000795,000 | $10M | 0.95% | — |
| 27 | VANGUARD PORTFOLIO MANAGEMENT LLC | 793,870793,870 | $10M | 0.95% | NEW |
| 28 | Artia Global Partners LP | 767,098767,098 | $10M | 0.92% | — |
| 29 | Sio Capital Management, LLC | 721,785721,785 | $9M | 0.87% | NEW |
| 30 | GOLDMAN SACHS GROUP INC | 699,706699,706 | $9M | 0.84% | TRIM -44% |
| 31 | NORTHERN TRUST CORP | 676,812676,812 | $9M | 0.81% | ADD 17% |
| 32 | Candriam S.C.A. | 674,395674,395 | $9M | 0.81% | — |
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 640,123640,123 | $8M | 0.77% | — |
| 34 | Alyeska Investment Group, L.P. | 509,403509,403 | $7M | 0.61% | TRIM -35% |
| 35 | VANGUARD FIDUCIARY TRUST CO | 504,472504,472 | $7M | 0.60% | NEW |
| 36 | MILLENNIUM MANAGEMENT LLC | 475,190475,190 | $6M | 0.57% | TRIM -15% |
| 37 | ExodusPoint Capital Management, LP | 458,102458,102 | $6M | 0.55% | TRIM -16% |
| 38 | TWO SIGMA INVESTMENTS, LP | 430,315430,315 | $6M | 0.52% | ADD 211% |
| 39 | AMERIPRISE FINANCIAL INC | 423,262423,262 | $5M | 0.51% | ADD 98% |
| 40 | DIMENSIONAL FUND ADVISORS LP | 401,121401,121 | $5M | 0.48% | — |
| 41 | BANK OF AMERICA CORP /DE/ | 383,443383,443 | $5M | 0.46% | TRIM -8% |
| 42 | MYDA Advisors LLC | 330,000330,000 | $4M | 0.40% | ADD 10% |
| 43 | Simplify Asset Management Inc. | 326,142326,142 | $4M | 0.39% | TRIM -13% |
| 44 | Bleichroeder LP | 316,515316,515 | $4M | 0.38% | — |
| 45 | Walleye Capital LLC | 300,184300,184 | $4M | 0.36% | NEW |
| 46 | Granahan Investment Management, LLC | 297,108297,108 | $4M | 0.36% | TRIM -19% |
| 47 | Nuveen, LLC | 260,276260,276 | $3M | 0.31% | ADD 44% |
| 48 | WELLINGTON MANAGEMENT GROUP LLP | 258,942258,942 | $3M | 0.31% | ADD 38% |
| 49 | Rock Springs Capital Management LP | 258,739258,739 | $3M | 0.31% | — |
| 50 | Bank of New York Mellon Corp | 255,381255,381 | $3M | 0.31% | — |
| 51 | BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 245,359245,359 | $3M | 0.29% | — |
| 52 | DEUTSCHE BANK AG\ | 239,062239,062 | $3M | 0.29% | ADD 5% |
| 53 | Propel Bio Management, LLC | 215,825215,825 | $3M | 0.26% | NEW |
| 54 | Schonfeld Strategic Advisors LLC | 207,120207,120 | $3M | 0.25% | TRIM -69% |
| 55 | SCHRODER INVESTMENT MANAGEMENT GROUP | 218,550218,550 | $3M | 0.26% | ADD 30% |
| 56 | Jump Financial, LLC | 198,400198,400 | $3M | 0.24% | NEW |
| 57 | HighVista Strategies LLC | 183,037183,037 | $2M | 0.22% | NEW |
| 58 | DIADEMA PARTNERS LP | 178,545178,545 | $2M | 0.21% | NEW |
| 59 | MARSHALL WACE, LLP | 161,784161,784 | $2M | 0.19% | NEW |
| 60 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 149,861149,861 | $2M | 0.18% | ADD 12654% |
| 61 | Swiss National Bank | 147,400147,400 | $2M | 0.18% | NEW |
| 62 | Susquehanna Portfolio Strategies, LLC | 139,375139,375 | $2M | 0.17% | ADD 86% |
| 63 | PANAGORA ASSET MANAGEMENT INC | 132,214132,214 | $2M | 0.16% | — |
| 64 | Invesco Ltd. | 131,941131,941 | $2M | 0.16% | TRIM -61% |
| 65 | UBS Group AG | 129,455129,455 | $2M | 0.16% | TRIM -31% |
| 66 | FMR LLC | 129,438129,438 | $2M | 0.16% | ADD 575% |
| 67 | ESSEX INVESTMENT MANAGEMENT CO LLC | 127,213127,213 | $2M | 0.15% | — |
| 68 | STATE OF WISCONSIN INVESTMENT BOARD | 126,705126,705 | $2M | 0.15% | ADD 110% |
| 69 | RENAISSANCE TECHNOLOGIES LLC | 117,300117,300 | $2M | 0.14% | ADD 90% |
| 70 | Qube Research & Technologies Ltd | 116,477116,477 | $2M | 0.14% | NEW |
| 71 | ALLIANCEBERNSTEIN L.P. | 75,33675,336 | $1M | 0.09% | — |
| 72 | PRICE T ROWE ASSOCIATES INC /MD/ | 106,138106,138 | $1M | 0.13% | ADD 15% |
| 73 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 105,101105,101 | $1M | 0.13% | ADD 2158% |
| 74 | Woodline Partners LP | 100,463100,463 | $1M | 0.12% | — |
| 75 | RHUMBLINE ADVISERS | 96,67796,677 | $1M | 0.12% | ADD 9% |
| 76 | E Fund Management Co., Ltd. | 94,50094,500 | $1M | 0.11% | NEW |
| 77 | Squarepoint Ops LLC | 80,11980,119 | $1M | 0.10% | NEW |
| 78 | Waverly Advisors, LLC | 77,91477,914 | $1M | 0.09% | — |
| 79 | Russell Investments Group, Ltd. | 71,63171,631 | $923,328 | 0.09% | ADD 1100% |
| 80 | WOODSTOCK CORP | 68,46568,465 | $882,514 | 0.08% | — |
| 81 | XTX Topco Ltd | 66,64666,646 | $859,067 | 0.08% | NEW |
| 82 | Persistent Asset Partners Ltd | 58,99558,995 | $760,446 | 0.07% | ADD 995% |
| 83 | Marex Group plc | 56,31356,313 | $725,875 | 0.07% | ADD 18% |
| 84 | TWINBEECH CAPITAL LP | 56,30056,300 | $725,707 | 0.07% | NEW |
| 85 | Legal & General Group Plc | 53,11753,117 | $684,679 | 0.06% | ADD 688% |
| 86 | SEI INVESTMENTS CO | 50,50650,506 | $651,022 | 0.06% | ADD 75% |
| 87 | SILVERBACK ASSET MANAGEMENT LLC | 50,00050,000 | $644,500 | 0.06% | NEW |
| 88 | VANGUARD ASSET MANAGEMENT, Ltd | 49,12949,129 | $633,273 | 0.06% | NEW |
| 89 | VOYA INVESTMENT MANAGEMENT LLC | 47,77147,771 | $615,768 | 0.06% | — |
| 90 | Erste Asset Management GmbH | 50,00050,000 | $592,500 | 0.06% | — |
| 91 | NISA INVESTMENT ADVISORS, LLC | 44,47244,472 | $573,244 | 0.05% | ADD 4% |
| 92 | MetLife Investment Management, LLC | 43,46943,469 | $560,315 | 0.05% | ADD 4% |
| 93 | BNP PARIBAS FINANCIAL MARKETS | 42,52342,523 | $548,121 | 0.05% | — |
| 94 | SBI Okasan Asset Management Co.Ltd. | 45,70045,700 | $541,545 | 0.05% | ADD 36% |
| 95 | SCOTIA CAPITAL INC. | 41,75141,751 | $538,170 | 0.05% | ADD 32% |
| 96 | Legato Capital Management LLC | 39,87539,875 | $513,989 | 0.05% | — |
| 97 | China Universal Asset Management Co., Ltd. | 39,69139,691 | $511,617 | 0.05% | ADD 35% |
| 98 | Vanguard Global Advisers, LLC | 38,88838,888 | $501,266 | 0.05% | NEW |
| 99 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 37,68137,681 | $485,708 | 0.05% | TRIM -73% |
| 100 | JANE STREET GROUP, LLC | 36,92936,929 | $476,014 | 0.04% | NEW |
† NEW this big is usually a rename.
Ranked by each filer’s own reported value, not shares.
1 holder — The filer reported no value for this line, so it carries no dollar figure and is left out of the percentage and value columns.
| Biggest buyers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD CAPITAL MANAGEMENT LLC | +3,559,569 | $46M | OPEN |
| Commodore Capital LP | +2,825,000 | $36M | OPEN |
| CITADEL ADVISORS LLC | +1,905,875 | $25M | OPEN |
| STEMPOINT CAPITAL LP | +1,267,679 | $16M | ADD |
| EVENTIDE ASSET MANAGEMENT, LLC | +1,245,583 | $16M | OPEN |
| Biggest sellers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD GROUP INC | −4,822,139 | $62M | CLOSE |
| TCG Crossover Management, LLC | −3,572,335 | $46M | CLOSE |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | −1,400,000 | $18M | TRIM |
| ORBIMED ADVISORS LLC | −1,399,167 | $18M | TRIM |
| Spruce Street Capital LP | −981,543 | $13M | CLOSE |
Prior quarter split-rebased · 13Fs are long, US-listed only.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| SUVRETTA CAPITAL MANAGEMENT, LLC | 6.8M | 6.8M | 6.8M | 6.2M | 7.8M | 8.3M | $107M |
| Cormorant Asset Management, LP | 8.3M | 8.3M | 8.3M | 8.3M | 8.3M | 8.3M | $107M |
| BlackRock, Inc. | 5.3M | 5.7M | 5.4M | 5.0M | 6.8M | 7.2M | $93M |
| FEDERATED HERMES, INC. | 3.7M | 4.1M | 4.6M | 4.4M | 6.0M | 5.7M | $73M |
| FRANKLIN RESOURCES INC | 4.1M | 4.1M | 4.3M | 4.2M | 5.0M | 5.0M | $65M |
| JANUS HENDERSON GROUP PLC | 27K | 27K | — | — | 2.9M | 3.6M | $46M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 3.6M | $46M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 5.8M | 6.2M | 6.8M | 5.6M | 4.7M | 3.3M | $43M |
| Paradigm Biocapital Advisors LP | — | — | — | 2.0M | 3.7M | 3.1M | $41M |
| Commodore Capital LP | — | — | — | — | — | 2.8M | $36M |
| STATE STREET CORP | 1.5M | 1.6M | 1.5M | 1.5M | 1.8M | 2.1M | $27M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.5M | 1.6M | 1.6M | 1.5M | 1.9M | 2.0M | $26M |
| CITADEL ADVISORS LLC | 2.5M | 2.3M | 2.3M | 2.1M | — | 1.9M | $25M |
| Aberdeen Group plc | 231K | 231K | 1.0M | 797K | 1.6M | 1.7M | $22M |
| STEMPOINT CAPITAL LP | 580K | — | 329K | — | 354K | 1.6M | $21M |
Green = added, red = trimmed, grey = held; a dash is a quarter with no 13F on file — a gap, not an exit.
Breaks = no 13F that quarter.
Short interest has its own tab now — open SI →
SEC Form 13F · ~10,250 filers, 10y · long-only, US-listed, filed ≤45d after quarter-end.
SEC Schedule 13D/G XML · group aggregate.