% of shares outstanding suppressed: the summed institutional 13F holdings (30,555,242) exceed the latest reported shares-outstanding count (23,099,173) by more than securities-lending double counting can explain (FINRA short interest 1,605,258 shares at 2026-04-30), so the share count is stale or wrong (common for annual 20-F foreign private issuers after a share issuance) and a percentage would be fabricated. Holder share counts are shown as filed.
| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | SUVRETTA CAPITAL MANAGEMENT, LLC | 2,841,3342.8M | $37M | — | — |
| 2 | JANUS HENDERSON GROUP PLC | 2,734,8362.7M | $36M | — | ADD 12% |
| 3 | JOHNSON & JOHNSON | 1,979,1732.0M | $26M | — | — |
| 4 | FRANKLIN RESOURCES INC | 1,839,2271.8M | $24M | — | TRIM -2% |
| 5 | Balyasny Asset Management L.P. | 1,685,6351.7M | $22M | — | TRIM -9% |
| 6 | MILLENNIUM MANAGEMENT LLC | 1,535,4491.5M | $20M | — | ADD 85% |
| 7 | BAKER BROS. ADVISORS LP | 1,420,8381.4M | $19M | — | — |
| 8 | RA CAPITAL MANAGEMENT, L.P. | 1,296,0121.3M | $17M | — | TRIM -41% |
| 9 | PERCEPTIVE ADVISORS LLC | 1,255,5921.3M | $16M | — | TRIM -14% |
| 10 | VANGUARD CAPITAL MANAGEMENT LLC | 1,214,1731.2M | $16M | — | NEW† |
| 11 | FMR LLC | 814,871814,871 | $11M | — | — |
| 12 | Ikarian Capital, LLC | 807,874807,874 | $11M | — | ADD 186% |
| 13 | GREAT POINT PARTNERS LLC | 800,198800,198 | $10M | — | — |
| 14 | Longaeva Partners L.P. | 732,088732,088 | $10M | — | ADD 56% |
| 15 | SECTORAL ASSET MANAGEMENT INC | 727,587727,587 | $10M | — | TRIM -9% |
| 16 | HHLR ADVISORS, LTD.tracked | 669,337669,337 | $9M | — | — |
| 17 | BlackRock, Inc. | 669,123669,123 | $9M | — | ADD 25% |
| 18 | RED TREE MANAGEMENT, LLC | 638,158638,158 | $8M | — | — |
| 19 | Versant Venture Management, LLC | 542,628542,628 | $7M | — | — |
| 20 | Jones Hill Capital LP | 513,053513,053 | $7M | — | NEW† |
| 21 | Boxer Capital Management, LLC | 494,000494,000 | $6M | — | — |
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 371,636371,636 | $5M | — | ADD 40% |
| 23 | CITADEL ADVISORS LLC | 350,200350,200 | $5M | — | NEW |
| 24 | GOLDMAN SACHS GROUP INC | 307,108307,108 | $4M | — | ADD 191% |
| 25 | SILVERARC CAPITAL MANAGEMENT, LLC | 301,729301,729 | $4M | — | — |
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 282,038282,038 | $4M | — | ADD 32% |
| 27 | ADAR1 Capital Management, LLC | 276,661276,661 | $4M | — | — |
| 28 | Qube Research & Technologies Ltd | 232,534232,534 | $3M | — | ADD 440% |
| 29 | UBS Group AG | 230,409230,409 | $3M | — | ADD 16% |
| 30 | MARSHALL WACE, LLP | 226,302226,302 | $3M | — | ADD 25% |
| 31 | BOOTHBAY FUND MANAGEMENT, LLC | 222,329222,329 | $3M | — | ADD 207% |
| 32 | SPHERA FUNDS MANAGEMENT LTD. | 173,475173,475 | $2M | — | — |
| 33 | VANGUARD FIDUCIARY TRUST CO | 153,924153,924 | $2M | — | NEW |
| 34 | Casdin Capital, LLC | 148,333148,333 | $2M | — | — |
| 35 | Eversept Partners, LP | 146,411146,411 | $2M | — | ADD 6% |
| 36 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 144,009144,009 | $2M | — | ADD 31% |
| 37 | Ishara Investments LP | 142,000142,000 | $2M | — | NEW |
| 38 | JANE STREET GROUP, LLC | 107,380107,380 | $1M | — | ADD 284% |
| 39 | STATE STREET CORP | 101,278101,278 | $1M | — | ADD 20% |
| 40 | Verdad Advisers, LP | 86,03286,032 | $1M | — | NEW |
| 41 | Point72 Asset Management, L.P. | 84,89184,891 | $1M | — | TRIM -89% |
| 42 | MORGAN STANLEY | 70,80170,801 | $924,661 | — | TRIM -43% |
| 43 | RENAISSANCE TECHNOLOGIES LLC | 69,40069,400 | $906,364 | — | ADD 22% |
| 44 | NORTHERN TRUST CORP | 65,92865,928 | $861,020 | — | ADD 22% |
| 45 | DIMENSIONAL FUND ADVISORS LP | 59,94659,946 | $782,102 | — | NEW |
| 46 | Squarepoint Ops LLC | 59,84459,844 | $781,563 | — | NEW |
| 47 | WELLINGTON MANAGEMENT GROUP LLP | 55,60955,609 | $726,254 | — | NEW |
| 48 | 683 Capital Management, LLC | 55,00055,000 | $718,300 | — | TRIM -40% |
| 49 | ACADIAN ASSET MANAGEMENT LLC | 54,06854,068 | $703,000 | — | TRIM -16% |
| 50 | Strategies Wealth Advisors, LLC | 50,00050,000 | $653,000 | — | — |
| 51 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 49,28049,280 | $643,597 | — | — |
| 52 | Trexquant Investment LP | 47,74647,746 | $623,563 | — | TRIM -19% |
| 53 | BANK OF AMERICA CORP /DE/ | 47,44947,449 | $619,684 | — | ADD 412% |
| 54 | BARCLAYS PLC | 43,95843,958 | $574,093 | — | TRIM -26% |
| 55 | Hudson Bay Capital Management LP | 42,81842,818 | $559,203 | — | ADD 65% |
| 56 | Brevan Howard Capital Management LP | 42,17842,178 | $550,845 | — | ADD 117% |
| 57 | BNP PARIBAS FINANCIAL MARKETS | 39,87939,879 | $520,820 | — | TRIM -38% |
| 58 | TWO SIGMA INVESTMENTS, LP | 37,91637,916 | $495,183 | — | — |
| 59 | XTX Topco Ltd | 35,84635,846 | $468,149 | — | NEW |
| 60 | AMERICAN CENTURY COMPANIES INC | 35,68135,681 | $465,994 | — | ADD 83% |
| 61 | Seven Fleet Capital Management LP | 27,05427,054 | $353,325 | — | NEW |
| 62 | INDEPENDENT FINANCIAL GROUP, LLC | 27,02127,021 | $352,894 | — | — |
| 63 | Jain Global LLC | 22,98422,984 | $300,171 | — | NEW |
| 64 | HRT FINANCIAL LP | 22,17022,170 | $289,000 | — | NEW |
| 65 | CANADA PENSION PLAN INVESTMENT BOARD | 20,60020,600 | $269,036 | — | NEW |
| 66 | RBF Capital, LLC | 20,00020,000 | $261,200 | — | TRIM -50% |
| 67 | Quarry LP | 16,00016,000 | $208,960 | — | NEW |
| 68 | Engineers Gate Manager LP | 14,95614,956 | $195,325 | — | NEW |
| 69 | OMERS ADMINISTRATION Corp | 14,20014,200 | $185,452 | — | TRIM -59% |
| 70 | China Universal Asset Management Co., Ltd. | 13,50313,503 | $176,349 | — | ADD 259% |
| 71 | Cannon Global Investment Management, LLC | 13,00013,000 | $169,780 | — | NEW |
| 72 | Quadrature Capital Ltd | 12,79912,799 | $167,155 | — | TRIM -45% |
| 73 | ExodusPoint Capital Management, LP | 12,38212,382 | $161,709 | — | TRIM -76% |
| 74 | PRICE T ROWE ASSOCIATES INC /MD/ | 11,30011,300 | $148,000 | — | — |
| 75 | Diametric Capital, LP | 10,72910,729 | $140,120 | — | NEW |
| 76 | Vanguard Global Advisers, LLC | 10,26510,265 | $134,061 | — | NEW |
| 77 | CITIGROUP INC | 8,8608,860 | $115,712 | — | TRIM -28% |
| 78 | ROYAL BANK OF CANADA | 5,7945,794 | $76,000 | — | ADD 73% |
| 79 | JPMORGAN CHASE & CO | 2,4882,488 | $31,000 | — | ADD 39% |
| 80 | Mirae Asset Global Investments Co., Ltd. | 1,5881,588 | $20,739 | — | ADD 42% |
| 81 | Federation des caisses Desjardins du Quebec | 1,2801,280 | $16,717 | — | TRIM -50% |
| 82 | CWM, LLC | 1,1451,145 | $14,954 | — | TRIM -3% |
| 83 | Tower Research Capital LLC (TRC) | 731731 | $9,547 | — | ADD 490% |
| 84 | GF FUND MANAGEMENT CO. LTD. | 513513 | $6,700 | — | ADD 13% |
| 85 | Torren Management, LLC | 254254 | $3,317 | — | TRIM -84% |
| 86 | Banque Transatlantique SA | 220220 | $2,946 | — | — |
| 87 | US BANCORP \DE\ | 123123 | $1,606 | — | NEW |
| 88 | Cornerstone Financial Management LLC | 6464 | $836 | — | — |
| 89 | OSAIC HOLDINGS, INC. | 66 | $78 | — | NEW |
| 90 | Caitong International Asset Management Co., Ltd | 11 | $13 | — | NEW |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| SUVRETTA CAPITAL MANAGEMENT, LLC | 1.7M | 1.7M | 1.7M | 1.7M | 2.8M | 2.8M | $37M |
| JANUS HENDERSON GROUP PLC | 68K | 42K | — | — | 2.4M | 2.7M | $36M |
| JOHNSON & JOHNSON | 2.0M | 2.0M | 2.0M | 2.0M | 2.0M | 2.0M | $26M |
| FRANKLIN RESOURCES INC | 1.4M | 1.6M | 1.7M | 1.7M | 1.9M | 1.8M | $24M |
| Balyasny Asset Management L.P. | — | — | — | 951K | 1.8M | 1.7M | $22M |
| MILLENNIUM MANAGEMENT LLC | — | — | 132K | 646K | 831K | 1.5M | $20M |
| BAKER BROS. ADVISORS LP | 313K | 313K | 313K | 78K | 1.4M | 1.4M | $19M |
| RA CAPITAL MANAGEMENT, L.P. | — | — | — | 2.1M | 2.2M | 1.3M | $17M |
| PERCEPTIVE ADVISORS LLC | 1.4M | 1.4M | 699K | 715K | 1.5M | 1.3M | $16M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 1.2M | $16M |
| FMR LLC | 692K | 810K | 843K | 815K | 815K | 815K | $11M |
| Ikarian Capital, LLC | — | — | — | — | 283K | 808K | $11M |
| GREAT POINT PARTNERS LLC | — | — | — | — | 800K | 800K | $10M |
| Longaeva Partners L.P. | — | — | — | — | 470K | 732K | $10M |
| SECTORAL ASSET MANAGEMENT INC | 801K | 801K | 801K | 801K | 801K | 728K | $10M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).
| Quarter | Holders | Shares held | % shares out | Value held |
|---|---|---|---|---|
| 2026-Q1 | 90 | 30,555,242 | — | $399M |
| 2025-Q4 | 80 | 29,622,181 | — | $338M |
| 2025-Q3 | 62 | 17,505,126 | 75.8% | $206M |
| 2025-Q2 | 70 | 13,886,723 | 60.1% | $55M |
| 2025-Q1 | 63 | 15,291,120 | 66.2% | $107M |
| 2024-Q4 | 62 | 15,786,103 | 68.3% | $231M |
| 2024-Q3 | 52 | 13,716,298 | 59.4% | $258M |
| 2024-Q2 | 49 | 13,019,468 | 56.4% | $229M |
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).
