CIK 1263508
Long positions in SEC Section 13(f) securities (US-listed stocks, ADRs and ETFs), largest first · Δ vs 2025-Q4. A lagged quarterly snapshot (filed ≤45 days after quarter-end); excludes shorts, options, cash, and shares listed only on non-US exchanges — foreign companies held via a US listing or ADR (e.g. Alibaba, TSMC) ARE included.
As filed = each book applied at its quarter-end (what the reported book did) · As copyable = applied at its statutory 45-day filing deadline (what a 13F follower could have earned).
Computing…
Hypothetical modeled performance constructed with hindsight — not actual results, and not indicative of future results. See the Disclaimer.
| Industry group | Weight | Names |
|---|---|---|
| Pharmaceuticals & Biotechnology | 75.54% | 73 |
| Life Sciences Tools & Services | 16.65% | 2 |
| Health Care Providers & Services | 6.45% | 3 |
| Unclassified | 1.26% | 5 |
| Health Care Equipment & Supplies | 0.10% | 1 |
| # | Ticker | Name | Sector | Weight |
|---|---|---|---|---|
| 1 | INCY | INCYTE CORP | Health Care | 16.62% |
| 2 | ONC | BeOne Medicines Ltd. | Health Care | 15.00% |
| 3 | INSM | INSMED Inc | Health Care | 6.97% |
| 4 | MDGL | MADRIGAL PHARMACEUTICALS, INC. | Health Care | 6.44% |
| 5 | ACAD | ACADIA PHARMACEUTICALS INC | Health Care | 5.48% |
| 6 | RVMD | Revolution Medicines, Inc. | Health Care | 5.34% |
| 7 | CELC | Celcuity Inc. | Health Care | 5.19% |
| 8 | KOD | Kodiak Sciences Inc. | Health Care | 4.36% |
| 9 | KYMR | Kymera Therapeutics, Inc. | Health Care | 4.14% |
| 10 | SMMT | Summit Therapeutics Inc. | Health Care | 3.96% |
79/84 names classified · sector 98.7% of weight · industry 98.7% · mkt cap 97.9%; unclassified names shown, never dropped.
Sector is classified on each name's CURRENT fundamentals, not point-in-time — apparent sector drift can reflect the market re-rating a holding, not a manager trade. 13F is a lagged quarterly snapshot of long positions in US-listed securities only — foreign companies held via a US listing or ADR ARE included, but shares listed only on non-US exchanges (plus shorts, options and cash) are not. Latest quarter: 98.7% of the book is sector-classified (unclassified names shown, never dropped).
Only 40% of book weight classified — the grid is NOT representative of the whole book.
Classified: 39.9% of book weight (5/83 names) · unclassified 60.1%: INSM, MDGL, RVMD, CELC, KOD, KYMR, SMMT, PRAX, RYTM, GRAL +68 more. Size: cap 70/20/10 bands; style: value/growth composite on our own metrics — not Morningstar's model.
No contribution data for this period.
| # | Security | Shares | Value | Weight | Δ QoQ |
|---|---|---|---|---|---|
| 1 | INCYINCYTE CORP | 30,744,412 | $2.9B | 16.6% | HOLD |
| 2 | ONCBEONE MEDICINES LTD | 8,799,053 | $2.6B | 15.0% | HOLD |
| 3 | INSMINSMED INC | 7,421,111 | $1.2B | 7.0% | ADD 13% |
| 4 | MDGLMADRIGAL PHARMACEUTICALS INC | 2,141,701 | $1.1B | 6.4% | HOLD |
| 5 | ACADACADIA PHARM | 42,896,690 | $955M | 5.5% | HOLD |
| 6 | RVMDREVOLUTION MEDICINES INC | 9,555,357 | $929M | 5.3% | HOLD |
| 7 | CELCCELCUITY INC | 7,915,792 | $904M | 5.2% | HOLD |
| 8 | KODKODIAK SCIENCES INC | 19,919,186 | $759M | 4.4% | HOLD |
| 9 | KYMRKYMERA THERAPEUTICS INC | 8,657,242 | $721M | 4.1% | HOLD |
| 10 | SMMTSUMMIT THERAPEUTICS INC | 36,391,063 | $690M | 4.0% | HOLD |
| 11 | PRAXPRAXIS PRECISION MEDICINES I | 1,753,198 | $565M | 3.2% | ADD 56% |
| 12 | RYTMRHYTHM PHARMACEUTICALS INC | 5,604,483 | $487M | 2.8% | HOLD |
| 13 | ALKSALKERMES PLC | 10,012,267 | $354M | 2.0% | HOLD |
| 14 | GRALGRAIL INC | 4,028,614 | $208M | 1.2% | ADD 93% |
| 15 | EWTXEDGEWISE THERAPEUTICS INC | 6,575,940 | $207M | 1.2% | HOLD |
| 16 | IONSIONIS PHARMACEUTICALS INC | 2,047,727 | $154M | 0.9% | ADD 14% |
| 17 | KNSAKINIKSA PHARMACEUTICALS INTL | 2,826,246 | $136M | 0.8% | HOLD |
| 18 | IMVTIMMUNOVANT INC | 5,457,881 | $136M | 0.8% | HOLD |
| 19 | ROIVROIVANT SCIENCES LTD | 4,867,723 | $135M | 0.8% | TRIM −12% |
| 20 | IDYAIDEAYA BIOSCIENCES INC | 3,946,515 | $131M | 0.8% | ADD 9% |
| 21 | ARWRARROWHEAD PHARMACEUTICALS IN | 1,992,783 | $125M | 0.7% | TRIM −8% |
| 22 | STOKSTOKE THERAPEUTICS INC | 3,336,697 | $109M | 0.6% | HOLD |
| 23 | IMTXIMMATICS N.V | 10,916,693 | $107M | 0.6% | TRIM −10% |
| 24 | ABCLABCELLERA BIOLOGICS INC | 30,275,938 | $106M | 0.6% | ADD 10% |
| 25 | ABVXABIVAX SA | 875,796 | $98M | 0.6% | HOLD |
| 26 | CRNXCRINETICS PHARMACEUTICALS IN | 2,351,465 | $85M | 0.5% | ADD 43% |
| 27 | REPLREPLIMUNE GROUP INC | 11,045,336 | $84M | 0.5% | HOLD |
| 28 | Celcuity Inc. | 30,750,000 | $75M | 0.4% | NEW |
| 29 | NRIXNURIX THERAPEUTICS INC | 4,658,556 | $72M | 0.4% | HOLD |
| 30 | DNLIDENALI THERAPEUTICS INC | 3,731,695 | $72M | 0.4% | HOLD |
| 31 | DNTHDIANTHUS THERAPEUTICS INC | 852,164 | $72M | 0.4% | ADD 8% |
| 32 | GLUEMONTE ROSA THERAPEUTICS INC | 4,345,736 | $71M | 0.4% | HOLD |
| 33 | GPCRSTRUCTURE THERAPEUTICS INC | 1,432,529 | $69M | 0.4% | HOLD |
| 34 | TRDAENTRADA THERAPEUTICS INC | 5,072,730 | $64M | 0.4% | HOLD |
| 35 | BCYCBICYCLE THERAPEUTICS PLC | 10,885,357 | $51M | 0.3% | HOLD |
| 36 | SYRESPYRE THERAPEUTICS INC | 1,000,000 | $50M | 0.3% | HOLD |
| 37 | RAPPRAPPORT THERAPEUTICS INC | 1,547,090 | $48M | 0.3% | HOLD |
| 38 | ALMSALUMIS INC | 2,012,500 | $44M | 0.3% | ADD 29% |
| 39 | MIRMMIRUM PHARMACEUTICALS INC | 445,975 | $41M | 0.2% | NEW |
| 40 | VRDNVIRIDIAN THERAPEUTICS INC | 1,971,678 | $39M | 0.2% | HOLD |
| 41 | ELVNENLIVEN THERAPEUTICS INC | 905,191 | $35M | 0.2% | ADD 234% |
| 42 | PRLDPRELUDE THERAPEUTICS INC | 10,123,824 | $35M | 0.2% | HOLD |
| 43 | DBVTDBV TECHNOLOGIES S A | 1,461,425 | $31M | 0.2% | HOLD |
| 44 | DSGNDESIGN THERAPEUTICS INC | 2,585,978 | $28M | 0.2% | ADD 16% |
| 45 | CENTESSA PHARMACEUTICALS PLC | 670,751 | $27M | 0.2% | HOLD |
| 46 | CTMXCYTOMX THERAPEUTICS INC. | 4,975,826 | $23M | 0.1% | ADD 17% |
| 47 | JBIOJADE BIOSCIENCES INC | 1,641,137 | $23M | 0.1% | HOLD |
| 48 | IRONDISC MEDICINE INC | 349,657 | $22M | 0.1% | ADD 4% |
| 49 | IMCRIMMUNOCORE HLDGS PLC | 734,397 | $22M | 0.1% | TRIM −68% |
| 50 | XENEXENON PHARMACEUTICALS INC | 370,208 | $22M | 0.1% | HOLD |
| 51 | CLDXCELLDEX THERAPEUTICS INC NEW | 665,370 | $21M | 0.1% | HOLD |
| 52 | NGNENEUROGENE INC | 991,691 | $20M | 0.1% | HOLD |
| 53 | EVMNEVOMMUNE INC | 847,390 | $19M | 0.1% | NEW |
| 54 | TECXTECTONIC THERAPEUTIC INC | 607,788 | $19M | 0.1% | TRIM −33% |
| 55 | CTNMCONTINEUM THERAPEUTICS INC | 1,420,838 | $19M | 0.1% | HOLD |
| 56 | ARGXARGENX SE | 25,174 | $18M | 0.1% | HOLD |
| 57 | CERSCERUS CORP | 10,008,345 | $18M | 0.1% | HOLD |
| 58 | TSHATAYSHA GENE THERAPIES INC | 4,004,756 | $18M | 0.1% | HOLD |
| 59 | AKTSAKTIS ONCOLOGY INC | 996,351 | $18M | 0.1% | NEW |
| 60 | GENBGENERATE BIOMEDICINES INC | 1,423,602 | $18M | 0.1% | NEW |
| 61 | SIONSIONNA THERAPEUTICS INC | 400,000 | $16M | 0.1% | HOLD |
| 62 | DYNDYNE THERAPEUTICS INC | 813,449 | $15M | 0.1% | HOLD |
| 63 | XNCRXENCOR INC | 1,102,106 | $13M | 0.1% | HOLD |
| 64 | CMPSCOMPASS PATHWAYS PLC | 2,344,720 | $13M | 0.1% | NEW |
| 65 | RLAYRELAY THERAPEUTICS INC | 1,160,117 | $12M | 0.1% | HOLD |
| 66 | SERASERA PROGNOSTICS INC | 5,498,170 | $11M | 0.1% | HOLD |
| 67 | BNTXBIONTECH SE | 119,743 | $11M | 0.1% | TRIM −68% |
| 68 | PHVSPHARVARIS N V | 375,000 | $11M | 0.1% | HOLD |
| 69 | RCUSARCUS BIOSCIENCES INC | 415,621 | $9M | 0.1% | ADD 54% |
| 70 | MPLTMAPLIGHT THERAPEUTICS INC | 364,705 | $7M | 0.0% | HOLD |
| 71 | ABSIABSCI CORPORATION | 2,134,803 | $6M | 0.0% | HOLD |
| 72 | WVEWAVE LIFE SCIENCES LTD | 822,638 | $6M | 0.0% | ADD 139% |
| 73 | VTVTVTV THERAPEUTICS INC | 148,314 | $6M | 0.0% | HOLD |
| 74 | EIKNEIKON THERAPEUTICS INC | 555,555 | $6M | 0.0% | NEW |
| 75 | TARAPROTARA THERAPEUTICS INC | 971,614 | $5M | 0.0% | HOLD |
| 76 | SGMTSAGIMET BIOSCIENCES INC | 952,996 | $5M | 0.0% | HOLD |
| 77 | LBRXLB PHARMACEUTICALS INC | 200,000 | $5M | 0.0% | HOLD |
| 78 | VSTMVERASTEM INC | 584,757 | $3M | 0.0% | NEW |
| 79 | TCRXTSCAN THERAPEUTICS INC | 2,784,792 | $3M | 0.0% | HOLD |
| 80 | SKYESKYE BIOSCIENCE INC | 1,575,243 | $968,144 | 0.0% | ADD 9% |
| 81 | SANASANA BIOTECHNOLOGY INC | 310,483 | $894,191 | 0.0% | HOLD |
| 82 | ALGSALIGOS THERAPEUTICS INC | 83,055 | $617,099 | 0.0% | HOLD |
| 83 | TYRATYRA BIOSCIENCES INC | 10,607 | $406,248 | 0.0% | HOLD |
| 84 | SRZNWSURROZEN INC | 833,333 | $13,333 | 0.0% | HOLD |
| Security | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| INCYINCYTE CORP | 30.7M | 30.7M | 30.7M | 30.7M | 30.7M | 30.7M | $2.9B |
| ONCBEONE MEDICINES LTD | 9.5M | 8.8M | 8.8M | 8.8M | 8.8M | 8.8M | $2.6B |
| INSMINSMED INC | 5.0M | 5.4M | 7.7M | 6.7M | 6.6M | 7.4M | $1.2B |
| MDGLMADRIGAL PHARMACEUTICALS INC | 2.0M | 2.0M | 2.0M | 2.1M | 2.1M | 2.1M | $1.1B |
| ACADACADIA PHARM | 42.9M | 42.9M | 42.9M | 42.9M | 42.9M | 42.9M | $955M |
| RVMDREVOLUTION MEDICINES INC | 7.9M | 7.9M | 9.4M | 9.5M | 9.5M | 9.6M | $929M |
| CELCCELCUITY INC | 2.7M | 4.3M | 5.5M | 7.9M | 7.9M | 7.9M | $904M |
| KODKODIAK SCIENCES INC | 17.3M | 17.3M | 17.3M | 17.3M | 19.9M | 19.9M | $759M |
| KYMRKYMERA THERAPEUTICS INC | 6.0M | 6.0M | 6.7M | 6.7M | 8.7M | 8.7M | $721M |
| SMMTSUMMIT THERAPEUTICS INC | 24.4M | 24.4M | 33.7M | 33.7M | 36.4M | 36.4M | $690M |
| PRAXPRAXIS PRECISION MEDICINES I | 332K | 332K | 689K | 689K | 1.1M | 1.8M | $565M |
| RYTMRHYTHM PHARMACEUTICALS INC | 6.1M | 5.6M | 5.6M | 5.6M | 5.6M | 5.6M | $487M |
| ALKSALKERMES PLC | 4.2M | 4.5M | 6.4M | 8.1M | 10.0M | 10.0M | $354M |
| GRALGRAIL INC | 1.6M | 1.6M | 1.6M | 1.6M | 2.1M | 4.0M | $208M |
| EWTXEDGEWISE THERAPEUTICS INC | 6.2M | 6.2M | 7.3M | 7.3M | 6.6M | 6.6M | $207M |
Shares reported each quarter by the largest current holdings. Green = added vs the prior filing of that name, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
