CELC US Equity

Celcuity Inc.

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Health Care · Services-Medical Laboratories · CIK 1603454 · FYE 1231

$83.26

+0.80 (+0.97%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding CELC · 2026-Q1 methodology → sources →

275 holders

% of shares outstanding held

100.7%

Shares held (13F)

49,097,982

Reporting holders

275

Institutional 13F holdings sum to 100.7% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 8,926,585 shares (settlement 2026-04-30) accounts for the excess.

Top holders

largest 100 of 275 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BAKER BROS. ADVISORS LP	7,915,7927.9M	$904M	16.23%	—
2	Avoro Capital Advisors LLC	3,375,0003.4M	$385M	6.92%	ADD 8%
3	PERCEPTIVE ADVISORS LLC	3,127,2003.1M	$357M	6.41%	—
4	RTW INVESTMENTS, LP	3,039,6213.0M	$347M	6.23%	ADD 452%
5	BlackRock, Inc.	2,711,5322.7M	$309M	5.56%	ADD 7%
6	NEA Management Company, LLC	2,285,5612.3M	$261M	4.69%	TRIM -35%
7	VANGUARD CAPITAL MANAGEMENT LLC	1,782,8941.8M	$203M	3.66%	NEW†
8	DEERFIELD MANAGEMENT COMPANY, L.P.	1,714,0001.7M	$196M	3.51%	—
9	STATE STREET CORP	1,518,7051.5M	$173M	3.11%	TRIM -7%
10	MORGAN STANLEY	1,345,7151.3M	$154M	2.76%	TRIM -4%
11	Soleus Capital Management, L.P.	1,284,3781.3M	$147M	2.63%	TRIM -29%
12	PRICE T ROWE ASSOCIATES INC /MD/	1,279,8161.3M	$146M	2.62%	ADD 3%
13	TANG CAPITAL MANAGEMENT LLC	1,050,0001.1M	$120M	2.15%	—
14	GEODE CAPITAL MANAGEMENT, LLC	891,070891,070	$102M	1.83%	ADD 7%
15	TORONTO DOMINION BANK	882,758882,758	$101M	1.81%	NEW
16	GOLDMAN SACHS GROUP INC	764,975764,975	$87M	1.57%	ADD 17%
17	BANK OF AMERICA CORP /DE/	714,329714,329	$82M	1.46%	TRIM -27%
18	Apis Capital Advisors, LLC	515,000515,000	$59M	1.06%	TRIM -14%
19	Nearwater Capital Markets, Ltd	473,100473,100	$54M	0.97%	TRIM -9%
20	Artisan Partners Limited Partnership	457,070457,070	$52M	0.94%	TRIM -16%
21	LORD, ABBETT & CO. LLC	439,221439,221	$50M	0.90%	ADD 142%
22	WELLINGTON MANAGEMENT GROUP LLP	428,952428,952	$49M	0.88%	ADD 16%
23	ALLIANCEBERNSTEIN L.P.	464,328464,328	$46M	0.95%	—
24	Holocene Advisors, LP	369,979369,979	$42M	0.76%	TRIM -47%
25	Sofinnova Investments, Inc.	366,175366,175	$42M	0.75%	ADD 22%
26	SILVERARC CAPITAL MANAGEMENT, LLC	357,903357,903	$41M	0.73%	TRIM -5%
27	NORTHERN TRUST CORP	318,766318,766	$36M	0.65%	ADD 11%
28	CAPITOLIS LIQUID GLOBAL MARKETS LLC	316,500316,500	$36M	0.65%	NEW
29	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	293,892293,892	$34M	0.60%	—
30	VANGUARD PORTFOLIO MANAGEMENT LLC	291,171291,171	$33M	0.60%	NEW
31	Saturn V Capital Management LP	281,904281,904	$32M	0.58%	TRIM -11%
32	Point72 Asset Management, L.P.	280,324280,324	$32M	0.57%	NEW
33	Pfizer Inc	295,652295,652	$31M	0.61%	TRIM -15%
34	VANGUARD FIDUCIARY TRUST CO	253,366253,366	$29M	0.52%	NEW
35	EVENTIDE ASSET MANAGEMENT, LLC	243,899243,899	$28M	0.50%	TRIM -22%
36	Driehaus Capital Management LLC	241,549241,549	$28M	0.50%	TRIM -3%
37	Focus Partners Wealth	233,390233,390	$27M	0.48%	—
38	JENNISON ASSOCIATES LLC	231,140231,140	$26M	0.47%	—
39	Candriam S.C.A.	230,603230,603	$26M	0.47%	TRIM -52%
40	Boxer Capital Management, LLC	225,000225,000	$26M	0.46%	—
41	UBS Group AG	220,163220,163	$25M	0.45%	ADD 170%
42	First Turn Management, LLC	210,578210,578	$24M	0.43%	NEW
43	Sio Capital Management, LLC	193,843193,843	$22M	0.40%	TRIM -59%
44	BNP PARIBAS FINANCIAL MARKETS	191,999191,999	$22M	0.39%	ADD 35%
45	Hennion & Walsh Asset Management, Inc.	182,601182,601	$21M	0.37%	TRIM -4%
46	Ensign Peak Advisors, Inc	148,994148,994	$17M	0.31%	—
47	Woodline Partners LP	145,033145,033	$17M	0.30%	ADD 11%
48	VOYA INVESTMENT MANAGEMENT LLC	133,191133,191	$15M	0.27%	ADD 27%
49	CITADEL ADVISORS LLC	131,906131,906	$15M	0.27%	ADD 180%
50	STEMPOINT CAPITAL LP	120,124120,124	$14M	0.25%	—
51	FEDERATED HERMES, INC.	119,048119,048	$14M	0.24%	NEW
52	RAYMOND JAMES FINANCIAL INC	117,457117,457	$13M	0.24%	—
53	Walleye Capital LLC	105,688105,688	$12M	0.22%	TRIM -31%
54	NAN FUNG TRINITY (HK) LTD	103,775103,775	$12M	0.21%	ADD 28%
55	AMERIPRISE FINANCIAL INC	98,71698,716	$11M	0.20%	TRIM -20%
56	Patient Square Capital LP	95,00095,000	$11M	0.19%	TRIM -21%
57	Bank of New York Mellon Corp	94,01594,015	$11M	0.19%	ADD 6%
58	Russell Investments Group, Ltd.	92,22892,228	$11M	0.19%	ADD 8%
59	Clearbridge Investments, LLC	91,76391,763	$10M	0.19%	TRIM -14%
60	ACT CAPITAL MANAGEMENT, LLC	91,67591,675	$10M	0.19%	ADD 45%
61	Invesco Ltd.	90,97690,976	$10M	0.19%	TRIM -39%
62	Granahan Investment Management, LLC	88,83388,833	$10M	0.18%	ADD 2%
63	TD Asset Management Inc	83,75683,756	$10M	0.17%	TRIM -14%
64	Integral Health Asset Management, LLC	80,00080,000	$9M	0.16%	—
65	Nuveen, LLC	76,65476,654	$9M	0.16%	TRIM -10%
66	Atom Investors LP	76,32176,321	$9M	0.16%	TRIM -11%
67	Alyeska Investment Group, L.P.	75,18275,182	$9M	0.15%	NEW
68	Freestone Grove Partners LP	70,53670,536	$8M	0.14%	NEW
69	MANUFACTURERS LIFE INSURANCE COMPANY, THE	67,66367,663	$8M	0.14%	TRIM -6%
70	CITIGROUP INC	66,22866,228	$8M	0.14%	ADD 722%
71	Balyasny Asset Management L.P.	64,41964,419	$7M	0.13%	ADD 1738%
72	CAPTRUST FINANCIAL ADVISORS	61,06861,068	$7M	0.13%	—
73	Harvest Investment Services, LLC	54,40754,407	$6M	0.11%	ADD 28%
74	GAGNON SECURITIES LLC	53,34253,342	$6M	0.11%	—
75	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	53,02353,023	$6M	0.11%	ADD 1532%
76	Connor, Clark & Lunn Investment Management Ltd.	52,07052,070	$6M	0.11%	ADD 343%
77	JPMORGAN CHASE & CO	53,86653,866	$6M	0.11%	ADD 5%
78	PRUDENTIAL FINANCIAL INC	50,51550,515	$6M	0.10%	ADD 31%
79	NEW YORK STATE COMMON RETIREMENT FUND	49,49849,498	$6M	0.10%	—
80	E Fund Management Co., Ltd.	46,33746,337	$5M	0.10%	NEW
81	Tidal Investments LLC	45,72545,725	$5M	0.09%	NEW
82	Tema ETFs LLC	45,72545,725	$5M	0.09%	ADD 64%
83	Atle Fund Management AB	141,296141,296	$5M	0.29%	ADD 238%
84	Man Group plc	44,17144,171	$5M	0.09%	TRIM -29%
85	Informed Momentum Co LLC	43,59143,591	$5M	0.09%	TRIM -9%
86	RHUMBLINE ADVISERS	43,09043,090	$5M	0.09%	ADD 13%
87	Swiss National Bank	41,20041,200	$5M	0.08%	ADD 64%
88	Rafferty Asset Management, LLC	38,96338,963	$4M	0.08%	TRIM -32%
89	ALPS ADVISORS INC	37,66337,663	$4M	0.08%	—
90	FMR LLC	36,36036,360	$4M	0.07%	ADD 36%
91	JNBA Financial Advisors	35,75335,753	$4M	0.07%	TRIM -3%
92	Creative Planning	35,21935,219	$4M	0.07%	ADD 68%
93	VICTORY CAPITAL MANAGEMENT INC	34,75334,753	$4M	0.07%	TRIM -16%
94	Schonfeld Strategic Advisors LLC	34,61034,610	$4M	0.07%	NEW
95	Qube Research & Technologies Ltd	33,05133,051	$4M	0.07%	TRIM -84%
96	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	30,79530,795	$4M	0.06%	ADD 102%
97	DEUTSCHE BANK AG\	30,31630,316	$3M	0.06%	ADD 29%
98	BRAIDWELL LP	29,19829,198	$3M	0.06%	NEW
99	BARCLAYS PLC	28,53728,537	$3M	0.06%	TRIM -77%
100	Nan Fung Group Holdings Ltd	28,30028,300	$3M	0.06%	NEW

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BAKER BROS. ADVISORS LP

2.7M

4.3M

5.5M

7.9M

$904M

Avoro Capital Advisors LLC

—

3.1M

3.4M

$385M

PERCEPTIVE ADVISORS LLC

2.4M

1.6M

3.0M

3.2M

3.1M

$357M

RTW INVESTMENTS, LP

—

550K

3.0M

$347M

BlackRock, Inc.

2.2M

2.1M

2.2M

2.5M

2.7M

$309M

NEA Management Company, LLC

1.3M

2.3M

2.1M

3.5M

2.3M

$261M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.8M

$203M

DEERFIELD MANAGEMENT COMPANY, L.P.

—

734K

1.7M

$196M

STATE STREET CORP

880K

585K

587K

723K

1.6M

1.5M

$173M

MORGAN STANLEY

877K

837K

784K

1.5M

1.4M

1.3M

$154M

Soleus Capital Management, L.P.

2.6M

3.0M

1.2M

1.8M

1.3M

$147M

PRICE T ROWE ASSOCIATES INC /MD/

13K

14K

15K

598K

1.2M

1.3M

$146M

TANG CAPITAL MANAGEMENT LLC

—

1.1M

$120M

GEODE CAPITAL MANAGEMENT, LLC

692K

720K

677K

766K

831K

891K

$102M

TORONTO DOMINION BANK

—

883K

$101M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	275	49,097,982	100.7%	$5.6B
2025-Q4	237	48,092,879	98.6%	$4.8B
2025-Q3	176	39,150,372	80.3%	$1.9B
2025-Q2	96	31,713,984	65.0%	$423M
2025-Q1	95	30,900,273	63.4%	$312M
2024-Q4	104	30,441,695	62.4%	$403M
2024-Q3

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · CELC

Activists — 13D, active intent

Growth Equity Opportunities 18 VGE, LLC4.9%▼ -1.4ppSCHEDULE 13D/A · Amd 4 · event 2026-03-05SEC →

2,285,561 shares · 12 reporting persons

“The information provided and incorporated by reference in Item 5(c) is hereby incorporated by reference. Depending on market conditions and other factors, GEO and other Reporting Persons may dispose of additional shares of the Issuer.”

Large holders — 13G, passive (top 5 of 11 by % of class)

Holder

% of class

Type

As of

BAKER BROS. ADVISORS LP

9.99%

QII

2026-07-14

SEC →

Soleus Capital Master Fund, L.P.

9.9%

Passive

2024-12-31

SEC →

Sullivan Brian F.

9.1%

Exempt

Institutional ownership· 13F filers holding CELC · 2026-Q1 methodology → sources →

275 holders

% of shares outstanding held

100.7%

Shares held (13F)

49,097,982

Reporting holders

275

Top holders

largest 100 of 275 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BAKER BROS. ADVISORS LP	7,915,7927.9M	$904M	16.23%	—
2	Avoro Capital Advisors LLC	3,375,0003.4M	$385M	6.92%	ADD 8%
3	PERCEPTIVE ADVISORS LLC	3,127,2003.1M	$357M	6.41%	—
4	RTW INVESTMENTS, LP	3,039,6213.0M	$347M	6.23%	ADD 452%
5	BlackRock, Inc.	2,711,5322.7M	$309M	5.56%	ADD 7%
6	NEA Management Company, LLC	2,285,5612.3M	$261M	4.69%	TRIM -35%
7	VANGUARD CAPITAL MANAGEMENT LLC	1,782,8941.8M	$203M	3.66%	NEW†
8	DEERFIELD MANAGEMENT COMPANY, L.P.	1,714,0001.7M	$196M	3.51%	—
9	STATE STREET CORP	1,518,7051.5M	$173M	3.11%	TRIM -7%
10	MORGAN STANLEY	1,345,7151.3M	$154M	2.76%	TRIM -4%
11	Soleus Capital Management, L.P.	1,284,3781.3M	$147M	2.63%	TRIM -29%
12	PRICE T ROWE ASSOCIATES INC /MD/	1,279,8161.3M	$146M	2.62%	ADD 3%
13	TANG CAPITAL MANAGEMENT LLC	1,050,0001.1M	$120M	2.15%	—
14	GEODE CAPITAL MANAGEMENT, LLC	891,070891,070	$102M	1.83%	ADD 7%
15	TORONTO DOMINION BANK	882,758882,758	$101M	1.81%	NEW
16	GOLDMAN SACHS GROUP INC	764,975764,975	$87M	1.57%	ADD 17%
17	BANK OF AMERICA CORP /DE/	714,329714,329	$82M	1.46%	TRIM -27%
18	Apis Capital Advisors, LLC	515,000515,000	$59M	1.06%	TRIM -14%
19	Nearwater Capital Markets, Ltd	473,100473,100	$54M	0.97%	TRIM -9%
20	Artisan Partners Limited Partnership	457,070457,070	$52M	0.94%	TRIM -16%
21	LORD, ABBETT & CO. LLC	439,221439,221	$50M	0.90%	ADD 142%
22	WELLINGTON MANAGEMENT GROUP LLP	428,952428,952	$49M	0.88%	ADD 16%
23	ALLIANCEBERNSTEIN L.P.	464,328464,328	$46M	0.95%	—
24	Holocene Advisors, LP	369,979369,979	$42M	0.76%	TRIM -47%
25	Sofinnova Investments, Inc.	366,175366,175	$42M	0.75%	ADD 22%
26	SILVERARC CAPITAL MANAGEMENT, LLC	357,903357,903	$41M	0.73%	TRIM -5%
27	NORTHERN TRUST CORP	318,766318,766	$36M	0.65%	ADD 11%
28	CAPITOLIS LIQUID GLOBAL MARKETS LLC	316,500316,500	$36M	0.65%	NEW
29	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	293,892293,892	$34M	0.60%	—
30	VANGUARD PORTFOLIO MANAGEMENT LLC	291,171291,171	$33M	0.60%	NEW
31	Saturn V Capital Management LP	281,904281,904	$32M	0.58%	TRIM -11%
32	Point72 Asset Management, L.P.	280,324280,324	$32M	0.57%	NEW
33	Pfizer Inc	295,652295,652	$31M	0.61%	TRIM -15%
34	VANGUARD FIDUCIARY TRUST CO	253,366253,366	$29M	0.52%	NEW
35	EVENTIDE ASSET MANAGEMENT, LLC	243,899243,899	$28M	0.50%	TRIM -22%
36	Driehaus Capital Management LLC	241,549241,549	$28M	0.50%	TRIM -3%
37	Focus Partners Wealth	233,390233,390	$27M	0.48%	—
38	JENNISON ASSOCIATES LLC	231,140231,140	$26M	0.47%	—
39	Candriam S.C.A.	230,603230,603	$26M	0.47%	TRIM -52%
40	Boxer Capital Management, LLC	225,000225,000	$26M	0.46%	—
41	UBS Group AG	220,163220,163	$25M	0.45%	ADD 170%
42	First Turn Management, LLC	210,578210,578	$24M	0.43%	NEW
43	Sio Capital Management, LLC	193,843193,843	$22M	0.40%	TRIM -59%
44	BNP PARIBAS FINANCIAL MARKETS	191,999191,999	$22M	0.39%	ADD 35%
45	Hennion & Walsh Asset Management, Inc.	182,601182,601	$21M	0.37%	TRIM -4%
46	Ensign Peak Advisors, Inc	148,994148,994	$17M	0.31%	—
47	Woodline Partners LP	145,033145,033	$17M	0.30%	ADD 11%
48	VOYA INVESTMENT MANAGEMENT LLC	133,191133,191	$15M	0.27%	ADD 27%
49	CITADEL ADVISORS LLC	131,906131,906	$15M	0.27%	ADD 180%
50	STEMPOINT CAPITAL LP	120,124120,124	$14M	0.25%	—
51	FEDERATED HERMES, INC.	119,048119,048	$14M	0.24%	NEW
52	RAYMOND JAMES FINANCIAL INC	117,457117,457	$13M	0.24%	—
53	Walleye Capital LLC	105,688105,688	$12M	0.22%	TRIM -31%
54	NAN FUNG TRINITY (HK) LTD	103,775103,775	$12M	0.21%	ADD 28%
55	AMERIPRISE FINANCIAL INC	98,71698,716	$11M	0.20%	TRIM -20%
56	Patient Square Capital LP	95,00095,000	$11M	0.19%	TRIM -21%
57	Bank of New York Mellon Corp	94,01594,015	$11M	0.19%	ADD 6%
58	Russell Investments Group, Ltd.	92,22892,228	$11M	0.19%	ADD 8%
59	Clearbridge Investments, LLC	91,76391,763	$10M	0.19%	TRIM -14%
60	ACT CAPITAL MANAGEMENT, LLC	91,67591,675	$10M	0.19%	ADD 45%
61	Invesco Ltd.	90,97690,976	$10M	0.19%	TRIM -39%
62	Granahan Investment Management, LLC	88,83388,833	$10M	0.18%	ADD 2%
63	TD Asset Management Inc	83,75683,756	$10M	0.17%	TRIM -14%
64	Integral Health Asset Management, LLC	80,00080,000	$9M	0.16%	—
65	Nuveen, LLC	76,65476,654	$9M	0.16%	TRIM -10%
66	Atom Investors LP	76,32176,321	$9M	0.16%	TRIM -11%
67	Alyeska Investment Group, L.P.	75,18275,182	$9M	0.15%	NEW
68	Freestone Grove Partners LP	70,53670,536	$8M	0.14%	NEW
69	MANUFACTURERS LIFE INSURANCE COMPANY, THE	67,66367,663	$8M	0.14%	TRIM -6%
70	CITIGROUP INC	66,22866,228	$8M	0.14%	ADD 722%
71	Balyasny Asset Management L.P.	64,41964,419	$7M	0.13%	ADD 1738%
72	CAPTRUST FINANCIAL ADVISORS	61,06861,068	$7M	0.13%	—
73	Harvest Investment Services, LLC	54,40754,407	$6M	0.11%	ADD 28%
74	GAGNON SECURITIES LLC	53,34253,342	$6M	0.11%	—
75	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	53,02353,023	$6M	0.11%	ADD 1532%
76	Connor, Clark & Lunn Investment Management Ltd.	52,07052,070	$6M	0.11%	ADD 343%
77	JPMORGAN CHASE & CO	53,86653,866	$6M	0.11%	ADD 5%
78	PRUDENTIAL FINANCIAL INC	50,51550,515	$6M	0.10%	ADD 31%
79	NEW YORK STATE COMMON RETIREMENT FUND	49,49849,498	$6M	0.10%	—
80	E Fund Management Co., Ltd.	46,33746,337	$5M	0.10%	NEW
81	Tidal Investments LLC	45,72545,725	$5M	0.09%	NEW
82	Tema ETFs LLC	45,72545,725	$5M	0.09%	ADD 64%
83	Atle Fund Management AB	141,296141,296	$5M	0.29%	ADD 238%
84	Man Group plc	44,17144,171	$5M	0.09%	TRIM -29%
85	Informed Momentum Co LLC	43,59143,591	$5M	0.09%	TRIM -9%
86	RHUMBLINE ADVISERS	43,09043,090	$5M	0.09%	ADD 13%
87	Swiss National Bank	41,20041,200	$5M	0.08%	ADD 64%
88	Rafferty Asset Management, LLC	38,96338,963	$4M	0.08%	TRIM -32%
89	ALPS ADVISORS INC	37,66337,663	$4M	0.08%	—
90	FMR LLC	36,36036,360	$4M	0.07%	ADD 36%
91	JNBA Financial Advisors	35,75335,753	$4M	0.07%	TRIM -3%
92	Creative Planning	35,21935,219	$4M	0.07%	ADD 68%
93	VICTORY CAPITAL MANAGEMENT INC	34,75334,753	$4M	0.07%	TRIM -16%
94	Schonfeld Strategic Advisors LLC	34,61034,610	$4M	0.07%	NEW
95	Qube Research & Technologies Ltd	33,05133,051	$4M	0.07%	TRIM -84%
96	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	30,79530,795	$4M	0.06%	ADD 102%
97	DEUTSCHE BANK AG\	30,31630,316	$3M	0.06%	ADD 29%
98	BRAIDWELL LP	29,19829,198	$3M	0.06%	NEW
99	BARCLAYS PLC	28,53728,537	$3M	0.06%	TRIM -77%
100	Nan Fung Group Holdings Ltd	28,30028,300	$3M	0.06%	NEW

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BAKER BROS. ADVISORS LP

2.7M

4.3M

5.5M

7.9M

$904M

Avoro Capital Advisors LLC

—

3.1M

3.4M

$385M

PERCEPTIVE ADVISORS LLC

2.4M

1.6M

3.0M

3.2M

3.1M

$357M

RTW INVESTMENTS, LP

—

550K

3.0M

$347M

BlackRock, Inc.

2.2M

2.1M

2.2M

2.5M

2.7M

$309M

NEA Management Company, LLC

1.3M

2.3M

2.1M

3.5M

2.3M

$261M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.8M

$203M

DEERFIELD MANAGEMENT COMPANY, L.P.

—

734K

1.7M

$196M

STATE STREET CORP

880K

585K

587K

723K

1.6M

1.5M

$173M

MORGAN STANLEY

877K

837K

784K

1.5M

1.4M

1.3M

$154M

Soleus Capital Management, L.P.

2.6M

3.0M

1.2M

1.8M

1.3M

$147M

PRICE T ROWE ASSOCIATES INC /MD/

13K

14K

15K

598K

1.2M

1.3M

$146M

TANG CAPITAL MANAGEMENT LLC

—

1.1M

$120M

GEODE CAPITAL MANAGEMENT, LLC

692K

720K

677K

766K

831K

891K

$102M

TORONTO DOMINION BANK

—

883K

$101M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	275	49,097,982	100.7%	$5.6B
2025-Q4	237	48,092,879	98.6%	$4.8B
2025-Q3	176	39,150,372	80.3%	$1.9B
2025-Q2	96	31,713,984	65.0%	$423M
2025-Q1	95	30,900,273	63.4%	$312M
2024-Q4	104	30,441,695	62.4%	$403M
2024-Q3

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · CELC

Activists — 13D, active intent

Growth Equity Opportunities 18 VGE, LLC4.9%▼ -1.4ppSCHEDULE 13D/A · Amd 4 · event 2026-03-05SEC →

2,285,561 shares · 12 reporting persons

Large holders — 13G, passive (top 5 of 11 by % of class)

Holder

% of class

Type

As of

BAKER BROS. ADVISORS LP

9.99%

QII

2026-07-14

SEC →

Soleus Capital Master Fund, L.P.

9.9%

Passive

2024-12-31

SEC →

Sullivan Brian F.

9.1%

Exempt

CELC US Equity☆

Institutional ownership· 13F filers holding CELC · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · CELC

Institutional ownership· 13F filers holding CELC · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · CELC

CELC US Equity