HALO vs NBIX
Halozyme Therapeutics, Inc. (HALO) and Neurocrine Biosciences Inc (NBIX) are both filed with the SEC under Biological Products, (No Diagnostic Substances). NBIX is 1.3× HALO's size by market cap ($15.8B against $12.1B); HALO trades at the higher fiscal-year P/E (41.8× against 33.4×); HALO reports the higher net margin (22.7% against 16.7%); HALO grew sales faster over three years (+28.4% against +24.3%); and over the past year HALO returned +44.7% against NBIX's +10.9%.
| HALO | NBIX | |
|---|---|---|
| Last close | $105.35 | $154.06 |
| Market cap | $12.1B | $15.8B |
| P/E (FY) | 41.8× | 33.4× |
| P/S | 8.7× | 5.5× |
| EV/EBITDA | 29.4× | — |
| Operating margin | 33.6% | 21.6% |
| Net margin | 22.7% | 16.7% |
| Return on equity | 153.6% | 16.4% |
| Sales growth (3y) | +28.4% | +24.3% |
| EPS growth (3y) | +21.1% | +44.1% |
| 1-year return | +44.7% | +10.9% |
Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year — FY2025 (ended 2025-12-31) for both. A return on equity past ±100% — HALO at 153.6% — divides earnings by an average filed equity base smaller in magnitude than the earnings themselves; the two columns are not on one scale. — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.
Who holds them, and who has traded them
| HALO | NBIX | |
|---|---|---|
| Institutional holders (13F) | 633 | 691 |
| Insider buyers − sellers (180d) | -4 | -5 |
| Congressional trades disclosed (180d) | 1 | 0 |
| Executive-branch officials on file — trades disclosed (180d) | 0 | 0 |
Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5.
HALO vs NBIX: common questions
- Is HALO bigger than NBIX?
- NBIX carries the larger market cap — $15.8B against $12.1B, both struck on 2026-08-27.
- Which trades at a higher P/E, HALO or NBIX?
- HALO, at a fiscal-year 41.8× against 33.4× for NBIX. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
- How have HALO and NBIX performed over the past year?
- HALO returned +44.7% and NBIX +10.9%, measured on the trailing calendar year to the last close.
- How many institutions hold HALO and NBIX?
- 633 13F filers report a position in HALO and 691 in NBIX, on the latest quarter in the panel.
- Are HALO and NBIX in the same industry?
- Both are filed with the SEC under Biological Products, (No Diagnostic Substances), which is the classification this pairing is built on.
HALO overview → · NBIX overview → · HALO institutional ownership → · NBIX institutional ownership → · Congress and HALO →
More in Biological Products, (No Diagnostic Substances): AMGN vs BIIB · AMGN vs EXEL · AMGN vs GILD · AMGN vs HALO
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Source: SPZCO — https://spzco.com/vs/halo-vs-nbix