Skip to content
KStart free
AI InfrastructureDefenseQuantumAll studies →

AMGN vs GILD

Amgen Inc (AMGN) and Gilead Sciences, Inc. (GILD) are both filed with the SEC under Biological Products, (No Diagnostic Substances). AMGN is 1.3× GILD's size by market cap ($236.3B against $184.6B); AMGN trades at the higher fiscal-year P/E (30.7× against 22.0×); GILD reports the higher net margin (28.9% against 21.0%); AMGN grew sales faster over three years (+11.8% against +2.6%); and over the past year AMGN returned +54.7% against GILD's +31.9%.

AMGNGILD
Last close$432.42$145.68
Market cap$236.3B$184.6B
P/E (FY)30.7×22.0×
P/S6.4×6.3×
EV/EBITDA19.8×
Operating margin24.7%34.0%
Net margin21.0%28.9%
Return on equity106.1%40.5%
Sales growth (3y)+11.8%+2.6%
EPS growth (3y)+5.5%+23.0%
Dividend yield2.2%2.2%
1-year return+54.7%+31.9%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year — FY2025 (ended 2025-12-31) for both. A return on equity past ±100% — AMGN at 106.1% — divides earnings by an average filed equity base smaller in magnitude than the earnings themselves; the two columns are not on one scale. — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

AMGNGILD
Institutional holders (13F)3,1072,295
Insider buyers − sellers (180d)-1-3
Congressional trades disclosed (180d)43
Executive-branch officials on file — trades disclosed (180d)1110

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5.

AMGN vs GILD: common questions

Is AMGN bigger than GILD?
AMGN carries the larger market cap — $236.3B against $184.6B, both struck on 2026-08-27.
Which trades at a higher P/E, AMGN or GILD?
AMGN, at a fiscal-year 30.7× against 22.0× for GILD. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have AMGN and GILD performed over the past year?
AMGN returned +54.7% and GILD +31.9%, measured on the trailing calendar year to the last close.
How many institutions hold AMGN and GILD?
3,107 13F filers report a position in AMGN and 2,295 in GILD, on the latest quarter in the panel.
Are AMGN and GILD in the same industry?
Both are filed with the SEC under Biological Products, (No Diagnostic Substances), which is the classification this pairing is built on.

AMGN overview · GILD overview · AMGN institutional ownership · GILD institutional ownership · Congress and AMGN · Congress and GILD · Executive branch and AMGN · Executive branch and GILD

More in Biological Products, (No Diagnostic Substances): AMGN vs BIIB · AMGN vs EXEL · AMGN vs HALO · AMGN vs NBIX

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/amgn-vs-gild