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AMGN vs BIIB

Amgen Inc (AMGN) and Biogen Inc. (BIIB) are both filed with the SEC under Biological Products, (No Diagnostic Substances). AMGN is 7.2× BIIB's size by market cap ($236.3B against $32.7B); AMGN trades at the higher fiscal-year P/E (30.7× against 25.2×); AMGN reports the higher net margin (21.0% against 13.1%); AMGN grew sales faster over three years (+11.8% against -0.9%); and over the past year BIIB returned +64.7% against AMGN's +54.7%.

AMGNBIIB
Last close$432.42$218.50
Market cap$236.3B$32.7B
P/E (FY)30.7×25.2×
P/S6.4×3.3×
EV/EBITDA19.8×
Operating margin24.7%28.7%
Net margin21.0%13.1%
Return on equity106.1%
Sales growth (3y)+11.8%-0.9%
EPS growth (3y)+5.5%-25.0%
Dividend yield2.2%
1-year return+54.7%+64.7%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year — FY2025 (ended 2025-12-31) for both. A return on equity past ±100% — AMGN at 106.1% — divides earnings by an average filed equity base smaller in magnitude than the earnings themselves; the two columns are not on one scale. — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

AMGNBIIB
Institutional holders (13F)3,107997
Insider buyers − sellers (180d)-1
Congressional trades disclosed (180d)46
Executive-branch officials on file — trades disclosed (180d)113

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5. — no open-market Form 4 purchases or sales in the window.

AMGN vs BIIB: common questions

Is AMGN bigger than BIIB?
AMGN carries the larger market cap — $236.3B against $32.7B, both struck on 2026-08-27.
Which trades at a higher P/E, AMGN or BIIB?
AMGN, at a fiscal-year 30.7× against 25.2× for BIIB. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have AMGN and BIIB performed over the past year?
BIIB returned +64.7% and AMGN +54.7%, measured on the trailing calendar year to the last close.
How many institutions hold AMGN and BIIB?
3,107 13F filers report a position in AMGN and 997 in BIIB, on the latest quarter in the panel.
Are AMGN and BIIB in the same industry?
Both are filed with the SEC under Biological Products, (No Diagnostic Substances), which is the classification this pairing is built on.

AMGN overview · BIIB overview · AMGN institutional ownership · BIIB institutional ownership · Congress and AMGN · Congress and BIIB · Executive branch and AMGN · Executive branch and BIIB

More in Biological Products, (No Diagnostic Substances): AMGN vs EXEL · AMGN vs GILD · AMGN vs HALO · AMGN vs NBIX

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/amgn-vs-biib