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GILD vs HALO

Gilead Sciences, Inc. (GILD) and Halozyme Therapeutics, Inc. (HALO) are both filed with the SEC under Biological Products, (No Diagnostic Substances). GILD is 15.2× HALO's size by market cap ($184.6B against $12.1B); HALO trades at the higher fiscal-year P/E (41.8× against 22.0×); GILD reports the higher net margin (28.9% against 22.7%); HALO grew sales faster over three years (+28.4% against +2.6%); and over the past year HALO returned +44.7% against GILD's +31.9%.

GILDHALO
Last close$145.68$105.35
Market cap$184.6B$12.1B
P/E (FY)22.0×41.8×
P/S6.3×8.7×
EV/EBITDA29.4×
Operating margin34.0%33.6%
Net margin28.9%22.7%
Return on equity40.5%153.6%
Sales growth (3y)+2.6%+28.4%
EPS growth (3y)+23.0%+21.1%
Dividend yield2.2%
1-year return+31.9%+44.7%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year — FY2025 (ended 2025-12-31) for both. A return on equity past ±100% — HALO at 153.6% — divides earnings by an average filed equity base smaller in magnitude than the earnings themselves; the two columns are not on one scale. — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

GILDHALO
Institutional holders (13F)2,295633
Insider buyers − sellers (180d)-3-4
Congressional trades disclosed (180d)31
Executive-branch officials on file — trades disclosed (180d)100

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5.

GILD vs HALO: common questions

Is GILD bigger than HALO?
GILD carries the larger market cap — $184.6B against $12.1B, both struck on 2026-08-27.
Which trades at a higher P/E, GILD or HALO?
HALO, at a fiscal-year 41.8× against 22.0× for GILD. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have GILD and HALO performed over the past year?
HALO returned +44.7% and GILD +31.9%, measured on the trailing calendar year to the last close.
How many institutions hold GILD and HALO?
2,295 13F filers report a position in GILD and 633 in HALO, on the latest quarter in the panel.
Are GILD and HALO in the same industry?
Both are filed with the SEC under Biological Products, (No Diagnostic Substances), which is the classification this pairing is built on.

GILD overview · HALO overview · GILD institutional ownership · HALO institutional ownership · Congress and GILD · Congress and HALO · Executive branch and GILD

More in Biological Products, (No Diagnostic Substances): AMGN vs BIIB · AMGN vs EXEL · AMGN vs GILD · AMGN vs HALO

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/gild-vs-halo