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EXEL vs GILD

Exelixis, Inc. (EXEL) and Gilead Sciences, Inc. (GILD) are both filed with the SEC under Biological Products, (No Diagnostic Substances). GILD is 13.5× EXEL's size by market cap ($184.6B against $13.7B); EXEL trades at the higher fiscal-year P/E (31.4× against 22.0×); EXEL reports the higher net margin (33.7% against 28.9%); EXEL grew sales faster over three years (+12.9% against +2.6%); and over the past year EXEL returned +43.7% against GILD's +31.9%.

EXELGILD
Last close$54.45$145.68
Market cap$13.7B$184.6B
P/E (FY)31.4×22.0×
P/S5.9×6.3×
Operating margin37.6%34.0%
Net margin33.7%28.9%
Return on equity35.5%40.5%
Sales growth (3y)+12.9%+2.6%
EPS growth (3y)+70.6%+23.0%
Dividend yield2.2%
1-year return+43.7%+31.9%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year, and the two differ: EXEL FY2026 (ended 2026-01-02); GILD FY2025 (ended 2025-12-31). — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

EXELGILD
Institutional holders (13F)6932,295
Insider buyers − sellers (180d)-5-3
Congressional trades disclosed (180d)03
Executive-branch officials on file — trades disclosed (180d)010

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5.

EXEL vs GILD: common questions

Is EXEL bigger than GILD?
GILD carries the larger market cap — $184.6B against $13.7B, both struck on 2026-08-27.
Which trades at a higher P/E, EXEL or GILD?
EXEL, at a fiscal-year 31.4× against 22.0× for GILD. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have EXEL and GILD performed over the past year?
EXEL returned +43.7% and GILD +31.9%, measured on the trailing calendar year to the last close.
How many institutions hold EXEL and GILD?
693 13F filers report a position in EXEL and 2,295 in GILD, on the latest quarter in the panel.
Are EXEL and GILD in the same industry?
Both are filed with the SEC under Biological Products, (No Diagnostic Substances), which is the classification this pairing is built on.

EXEL overview · GILD overview · EXEL institutional ownership · GILD institutional ownership · Congress and GILD · Executive branch and GILD

More in Biological Products, (No Diagnostic Substances): AMGN vs BIIB · AMGN vs EXEL · AMGN vs GILD · AMGN vs HALO

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/exel-vs-gild