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BIIB vs NBIX

Biogen Inc. (BIIB) and Neurocrine Biosciences Inc (NBIX) are both filed with the SEC under Biological Products, (No Diagnostic Substances). BIIB is 2.1× NBIX's size by market cap ($32.7B against $15.8B); NBIX trades at the higher fiscal-year P/E (33.4× against 25.2×); NBIX reports the higher net margin (16.7% against 13.1%); NBIX grew sales faster over three years (+24.3% against -0.9%); and over the past year BIIB returned +64.7% against NBIX's +10.9%.

BIIBNBIX
Last close$218.50$154.06
Market cap$32.7B$15.8B
P/E (FY)25.2×33.4×
P/S3.3×5.5×
Operating margin28.7%21.6%
Net margin13.1%16.7%
Return on equity16.4%
Sales growth (3y)-0.9%+24.3%
EPS growth (3y)-25.0%+44.1%
1-year return+64.7%+10.9%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year — FY2025 (ended 2025-12-31) for both. — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

BIIBNBIX
Institutional holders (13F)997691
Insider buyers − sellers (180d)-5
Congressional trades disclosed (180d)60
Executive-branch officials on file — trades disclosed (180d)30

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5. — no open-market Form 4 purchases or sales in the window.

BIIB vs NBIX: common questions

Is BIIB bigger than NBIX?
BIIB carries the larger market cap — $32.7B against $15.8B, both struck on 2026-08-27.
Which trades at a higher P/E, BIIB or NBIX?
NBIX, at a fiscal-year 33.4× against 25.2× for BIIB. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have BIIB and NBIX performed over the past year?
BIIB returned +64.7% and NBIX +10.9%, measured on the trailing calendar year to the last close.
How many institutions hold BIIB and NBIX?
997 13F filers report a position in BIIB and 691 in NBIX, on the latest quarter in the panel.
Are BIIB and NBIX in the same industry?
Both are filed with the SEC under Biological Products, (No Diagnostic Substances), which is the classification this pairing is built on.

BIIB overview · NBIX overview · BIIB institutional ownership · NBIX institutional ownership · Congress and BIIB · Executive branch and BIIB

More in Biological Products, (No Diagnostic Substances): AMGN vs BIIB · AMGN vs EXEL · AMGN vs GILD · AMGN vs HALO

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/biib-vs-nbix