WVE US Equity

Wave Life Sciences Ltd.

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Health Care · Pharmaceutical Preparations · CIK 1631574 · FYE 1231

$5.81

-0.08 (-1.36%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding WVE · 2026-Q1 methodology → sources →

229 holders

% of shares outstanding held

89.7%

Shares held (13F)

172,603,774

Reporting holders

229

Top holders

largest 100 of 229 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	RA CAPITAL MANAGEMENT, L.P.	26,975,50527.0M	$196M	14.02%	ADD 48%
2	GSK plc	18,245,69118.2M	$132M	9.48%	—
3	BlackRock, Inc.	14,117,41214.1M	$102M	7.34%	ADD 12%
4	MAVERICK CAPITAL LTD	10,161,39910.2M	$74M	5.28%	ADD 9%
5	PRICE T ROWE ASSOCIATES INC /MD/	8,704,5508.7M	$63M	4.52%	ADD 18%
6	Driehaus Capital Management LLC	5,431,0215.4M	$39M	2.82%	TRIM -17%
7	FEDERATED HERMES, INC.	5,317,4575.3M	$39M	2.76%	ADD 12%
8	FMR LLC	5,192,7615.2M	$38M	2.70%	TRIM -66%
9	683 Capital Management, LLC	4,900,0004.9M	$36M	2.55%	ADD 22%
10	PRIMECAP MANAGEMENT CO/CA/	4,832,9524.8M	$35M	2.51%	ADD 18%
11	M28 Capital Management LP	4,588,2844.6M	$33M	2.39%	TRIM -19%
12	STATE STREET CORP	3,674,0333.7M	$27M	1.91%	ADD 23%
13	GEODE CAPITAL MANAGEMENT, LLC	3,579,0993.6M	$26M	1.86%	ADD 13%
14	Siren, L.L.C.	2,450,0002.5M	$18M	1.27%	—
15	CITADEL ADVISORS LLC	2,202,8562.2M	$16M	1.15%	ADD 179%
16	TWO SIGMA INVESTMENTS, LP	1,878,1151.9M	$14M	0.98%	ADD 151%
17	First Light Asset Management, LLC	1,843,9681.8M	$13M	0.96%	—
18	MARSHALL WACE, LLP	1,789,8821.8M	$13M	0.93%	NEW
19	Pfizer Inc	1,875,0001.9M	$12M	0.97%	—
20	VANGUARD CAPITAL MANAGEMENT LLC	1,611,8531.6M	$12M	0.84%	NEW
21	Squarepoint Ops LLC	1,462,3901.5M	$11M	0.76%	ADD 66%
22	Affinity Asset Advisors, LLC	1,401,7271.4M	$10M	0.73%	TRIM -48%
23	GOLDMAN SACHS GROUP INC	1,383,5901.4M	$10M	0.72%	TRIM -52%
24	MORGAN STANLEY	1,361,0011.4M	$10M	0.71%	ADD 232%
25	RTW INVESTMENTS, LP	1,350,0001.4M	$10M	0.70%	—
26	SCHRODER INVESTMENT MANAGEMENT GROUP	1,441,0591.4M	$10M	0.75%	ADD 43%
27	ALGERT GLOBAL LLC	1,315,5891.3M	$10M	0.68%	ADD 974%
28	EMERALD ADVISERS, LLC	1,261,1831.3M	$9M	0.66%	TRIM -49%
29	NORTHERN TRUST CORP	1,189,2301.2M	$9M	0.62%	ADD 15%
30	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,179,2791.2M	$9M	0.61%	—
31	VANGUARD PORTFOLIO MANAGEMENT LLC	1,176,2071.2M	$9M	0.61%	NEW
32	Pictet Asset Management Holding SA	1,149,1271.1M	$8M	0.60%	ADD 43%
33	Trexquant Investment LP	1,089,6421.1M	$8M	0.57%	ADD 179%
34	ADAGE CAPITAL PARTNERS GP, L.L.C.	1,000,0001.0M	$7M	0.52%	TRIM -90%
35	MILLENNIUM MANAGEMENT LLC	972,241972,241	$7M	0.51%	ADD 66%
36	Kynam Capital Management, LP	965,193965,193	$7M	0.50%	TRIM -56%
37	VANGUARD FIDUCIARY TRUST CO	878,833878,833	$6M	0.46%	NEW
38	BAKER BROS. ADVISORS LP	822,638822,638	$6M	0.43%	ADD 139%
39	EMERALD MUTUAL FUND ADVISERS TRUST	814,529814,529	$6M	0.42%	TRIM -42%
40	SymBiosis Capital Partners, LLC	750,000750,000	$5M	0.39%	NEW
41	Nuveen, LLC	657,720657,720	$5M	0.34%	ADD 98%
42	Connor, Clark & Lunn Investment Management Ltd.	624,735624,735	$5M	0.32%	ADD 804%
43	JPMORGAN CHASE & CO	670,170670,170	$4M	0.35%	TRIM -25%
44	TANG CAPITAL MANAGEMENT LLC	600,000600,000	$4M	0.31%	—
45	RENAISSANCE TECHNOLOGIES LLC	597,220597,220	$4M	0.31%	ADD 153%
46	Aberdeen Group plc	550,000550,000	$4M	0.29%	NEW
47	SPHERA FUNDS MANAGEMENT LTD.	548,272548,272	$4M	0.28%	ADD 34%
48	UBS Group AG	538,997538,997	$4M	0.28%	ADD 101%
49	KENNEDY CAPITAL MANAGEMENT LLC	519,768519,768	$4M	0.27%	ADD 6%
50	CITIGROUP INC	501,477501,477	$4M	0.26%	ADD 972%
51	Walleye Capital LLC	493,512493,512	$4M	0.26%	ADD 30%
52	AQR CAPITAL MANAGEMENT LLC	451,185451,185	$3M	0.23%	ADD 123%
53	Universal- Beteiligungs- und Servicegesellschaft mbH	415,458415,458	$3M	0.22%	—
54	WELLINGTON MANAGEMENT GROUP LLP	373,794373,794	$3M	0.19%	ADD 2%
55	Bank of New York Mellon Corp	361,204361,204	$3M	0.19%	ADD 12%
56	Jump Financial, LLC	360,054360,054	$3M	0.19%	ADD 15%
57	Woodline Partners LP	350,531350,531	$3M	0.18%	—
58	TD Asset Management Inc	338,826338,826	$2M	0.18%	ADD 34%
59	Aquatic Capital Management LLC	323,573323,573	$2M	0.17%	NEW
60	HRT FINANCIAL LP	321,376321,376	$2M	0.17%	ADD 7%
61	Newtyn Management, LLC	300,000300,000	$2M	0.16%	—
62	ALLIANCEBERNSTEIN L.P.	125,096125,096	$2M	0.07%	ADD 12%
63	VOLORIDGE INVESTMENT MANAGEMENT, LLC	288,502288,502	$2M	0.15%	TRIM -60%
64	GSA CAPITAL PARTNERS LLP	282,719282,719	$2M	0.15%	NEW
65	BNP PARIBAS FINANCIAL MARKETS	281,023281,023	$2M	0.15%	ADD 243%
66	PLATINUM INVESTMENT MANAGEMENT LTD	275,269275,269	$2M	0.14%	ADD 19%
67	Moody Aldrich Partners LLC	272,533272,533	$2M	0.14%	—
68	SUSQUEHANNA INTERNATIONAL GROUP, LLP	259,825259,825	$2M	0.14%	TRIM -31%
69	Privium Fund Management B.V.	241,010241,010	$2M	0.13%	ADD 25%
70	MANUFACTURERS LIFE INSURANCE COMPANY, THE	240,983240,983	$2M	0.13%	ADD 32%
71	BANK OF AMERICA CORP /DE/	236,760236,760	$2M	0.12%	ADD 29%
72	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	225,114225,114	$2M	0.12%	ADD 36%
73	Swiss National Bank	219,700219,700	$2M	0.11%	—
74	Balyasny Asset Management L.P.	211,074211,074	$2M	0.11%	NEW
75	Scientech Research LLC	200,331200,331	$1M	0.10%	ADD 1186%
76	Invesco Ltd.	199,740199,740	$1M	0.10%	ADD 11%
77	Susquehanna Portfolio Strategies, LLC	195,840195,840	$1M	0.10%	TRIM -15%
78	BARCLAYS PLC	189,865189,865	$1M	0.10%	TRIM -31%
79	Sofinnova Investments, Inc.	189,253189,253	$1M	0.10%	ADD 20%
80	CAPITAL FUND MANAGEMENT S.A.	183,331183,331	$1M	0.10%	NEW
81	Caitong International Asset Management Co., Ltd	180,980180,980	$1M	0.09%	ADD 1647%
82	Elmind Capital, LP	177,846177,846	$1M	0.09%	TRIM -60%
83	Duquesne Family Office LLC	173,000173,000	$1M	0.09%	—
84	RHUMBLINE ADVISERS	167,528167,528	$1M	0.09%	ADD 18%
85	F/m Investments LLC	164,921164,921	$1M	0.09%	TRIM -58%
86	BOOTHBAY FUND MANAGEMENT, LLC	160,311160,311	$1M	0.08%	TRIM -32%
87	Y-Intercept (Hong Kong) Ltd	157,013157,013	$1M	0.08%	NEW
88	Qube Research & Technologies Ltd	155,924155,924	$1M	0.08%	NEW
89	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	150,368150,368	$1M	0.08%	ADD 12%
90	Burkehill Global Management, LP	150,000150,000	$1M	0.08%	—
91	TWINBEECH CAPITAL LP	145,825145,825	$1M	0.08%	NEW
92	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	145,206145,206	$1M	0.08%	ADD 35%
93	Advisory Services Network, LLC	144,950144,950	$1M	0.08%	ADD 594%
94	Capstone Capital Management Ltd	144,029144,029	$1M	0.07%	NEW
95	FRED ALGER MANAGEMENT, LLC	139,218139,218	$1M	0.07%	NEW
96	WELLS FARGO & COMPANY/MN	136,173136,173	$987,255	0.07%	TRIM -32%
97	James J. Burns & Company, LLC	114,800114,800	$832,300	0.06%	ADD 9%
98	DEUTSCHE BANK AG\	114,110114,110	$827,298	0.06%	ADD 19%
99	XTX Topco Ltd	109,862109,862	$796,500	0.06%	NEW
100	STATE OF WISCONSIN INVESTMENT BOARD	108,164108,164	$784,189	0.06%	ADD 24%

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

RA CAPITAL MANAGEMENT, L.P.

18.2M

27.0M

$196M

GSK plc

—

18.2M

$132M

BlackRock, Inc.

9.4M

9.6M

10.4M

12.6M

14.1M

$102M

MAVERICK CAPITAL LTD

8.3M

8.4M

9.3M

10.2M

$74M

PRICE T ROWE ASSOCIATES INC /MD/

5.1M

4.1M

5.2M

4.0M

7.4M

8.7M

$63M

Driehaus Capital Management LLC

6.7M

6.4M

6.5M

6.3M

6.6M

5.4M

$39M

FEDERATED HERMES, INC.

68K

56K

553

3.8M

4.7M

5.3M

$39M

FMR LLC

1.8M

2.1M

619K

5.1M

15.1M

5.2M

$38M

683 Capital Management, LLC

3.8M

3.9M

4.1M

4.2M

4.0M

4.9M

$36M

PRIMECAP MANAGEMENT CO/CA/

2.5M

1.9M

4.1M

4.8M

$35M

M28 Capital Management LP

5.7M

4.6M

$33M

STATE STREET CORP

2.4M

2.8M

3.0M

3.7M

$27M

GEODE CAPITAL MANAGEMENT, LLC

2.5M

2.6M

2.8M

2.9M

3.2M

3.6M

$26M

Siren, L.L.C.

3.8M

3.7M

2.5M

$18M

CITADEL ADVISORS LLC

62K

32K

—

790K

2.2M

$16M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	229	172,603,774	89.7%	$1.2B
2025-Q4	218	182,765,438	95.0%	$3.1B
2025-Q3	189	144,540,375	75.1%	$1.1B
2025-Q2	177	138,966,011	72.2%	$903M
2025-Q1

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · WVE

Activists — 13D, active intent

RA CAPITAL MANAGEMENT, L.P.17.1%▼ -0.4ppSCHEDULE 13D/A · Amd 10 · event 2026-04-15SEC →

34,225,506 shares · 4 reporting persons

“Item 4 of the Statement is hereby amended and supplemented as follows: On April 15, 2026, the Issuer into an Implementation Agreement, dated as of April 15, 2026 (the "Implementation Agreement"), with a newly established Delaware corporation, Wave Life Sciences, Inc. ("Wave-Delaware"). The Implementation Agreement provides for a statutory procedure known as a Scheme of Arrangement (the "Scheme of Arrangement") to be implemented by the Issuer and Wave-Delaware under Singapore law, subject to appr”

Large holders — 13G, passive (top 4 by % of class)

Holder	% of class	Type	As of
BlackRock, Inc.	6.1%	QII	2024-12-31	SEC →
MAVERICK CAPITAL LTD	5.4%	Passive	2024-12-31	SEC →

Institutional ownership· 13F filers holding WVE · 2026-Q1 methodology → sources →

229 holders

% of shares outstanding held

89.7%

Shares held (13F)

172,603,774

Reporting holders

229

Top holders

largest 100 of 229 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	RA CAPITAL MANAGEMENT, L.P.	26,975,50527.0M	$196M	14.02%	ADD 48%
2	GSK plc	18,245,69118.2M	$132M	9.48%	—
3	BlackRock, Inc.	14,117,41214.1M	$102M	7.34%	ADD 12%
4	MAVERICK CAPITAL LTD	10,161,39910.2M	$74M	5.28%	ADD 9%
5	PRICE T ROWE ASSOCIATES INC /MD/	8,704,5508.7M	$63M	4.52%	ADD 18%
6	Driehaus Capital Management LLC	5,431,0215.4M	$39M	2.82%	TRIM -17%
7	FEDERATED HERMES, INC.	5,317,4575.3M	$39M	2.76%	ADD 12%
8	FMR LLC	5,192,7615.2M	$38M	2.70%	TRIM -66%
9	683 Capital Management, LLC	4,900,0004.9M	$36M	2.55%	ADD 22%
10	PRIMECAP MANAGEMENT CO/CA/	4,832,9524.8M	$35M	2.51%	ADD 18%
11	M28 Capital Management LP	4,588,2844.6M	$33M	2.39%	TRIM -19%
12	STATE STREET CORP	3,674,0333.7M	$27M	1.91%	ADD 23%
13	GEODE CAPITAL MANAGEMENT, LLC	3,579,0993.6M	$26M	1.86%	ADD 13%
14	Siren, L.L.C.	2,450,0002.5M	$18M	1.27%	—
15	CITADEL ADVISORS LLC	2,202,8562.2M	$16M	1.15%	ADD 179%
16	TWO SIGMA INVESTMENTS, LP	1,878,1151.9M	$14M	0.98%	ADD 151%
17	First Light Asset Management, LLC	1,843,9681.8M	$13M	0.96%	—
18	MARSHALL WACE, LLP	1,789,8821.8M	$13M	0.93%	NEW
19	Pfizer Inc	1,875,0001.9M	$12M	0.97%	—
20	VANGUARD CAPITAL MANAGEMENT LLC	1,611,8531.6M	$12M	0.84%	NEW
21	Squarepoint Ops LLC	1,462,3901.5M	$11M	0.76%	ADD 66%
22	Affinity Asset Advisors, LLC	1,401,7271.4M	$10M	0.73%	TRIM -48%
23	GOLDMAN SACHS GROUP INC	1,383,5901.4M	$10M	0.72%	TRIM -52%
24	MORGAN STANLEY	1,361,0011.4M	$10M	0.71%	ADD 232%
25	RTW INVESTMENTS, LP	1,350,0001.4M	$10M	0.70%	—
26	SCHRODER INVESTMENT MANAGEMENT GROUP	1,441,0591.4M	$10M	0.75%	ADD 43%
27	ALGERT GLOBAL LLC	1,315,5891.3M	$10M	0.68%	ADD 974%
28	EMERALD ADVISERS, LLC	1,261,1831.3M	$9M	0.66%	TRIM -49%
29	NORTHERN TRUST CORP	1,189,2301.2M	$9M	0.62%	ADD 15%
30	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,179,2791.2M	$9M	0.61%	—
31	VANGUARD PORTFOLIO MANAGEMENT LLC	1,176,2071.2M	$9M	0.61%	NEW
32	Pictet Asset Management Holding SA	1,149,1271.1M	$8M	0.60%	ADD 43%
33	Trexquant Investment LP	1,089,6421.1M	$8M	0.57%	ADD 179%
34	ADAGE CAPITAL PARTNERS GP, L.L.C.	1,000,0001.0M	$7M	0.52%	TRIM -90%
35	MILLENNIUM MANAGEMENT LLC	972,241972,241	$7M	0.51%	ADD 66%
36	Kynam Capital Management, LP	965,193965,193	$7M	0.50%	TRIM -56%
37	VANGUARD FIDUCIARY TRUST CO	878,833878,833	$6M	0.46%	NEW
38	BAKER BROS. ADVISORS LP	822,638822,638	$6M	0.43%	ADD 139%
39	EMERALD MUTUAL FUND ADVISERS TRUST	814,529814,529	$6M	0.42%	TRIM -42%
40	SymBiosis Capital Partners, LLC	750,000750,000	$5M	0.39%	NEW
41	Nuveen, LLC	657,720657,720	$5M	0.34%	ADD 98%
42	Connor, Clark & Lunn Investment Management Ltd.	624,735624,735	$5M	0.32%	ADD 804%
43	JPMORGAN CHASE & CO	670,170670,170	$4M	0.35%	TRIM -25%
44	TANG CAPITAL MANAGEMENT LLC	600,000600,000	$4M	0.31%	—
45	RENAISSANCE TECHNOLOGIES LLC	597,220597,220	$4M	0.31%	ADD 153%
46	Aberdeen Group plc	550,000550,000	$4M	0.29%	NEW
47	SPHERA FUNDS MANAGEMENT LTD.	548,272548,272	$4M	0.28%	ADD 34%
48	UBS Group AG	538,997538,997	$4M	0.28%	ADD 101%
49	KENNEDY CAPITAL MANAGEMENT LLC	519,768519,768	$4M	0.27%	ADD 6%
50	CITIGROUP INC	501,477501,477	$4M	0.26%	ADD 972%
51	Walleye Capital LLC	493,512493,512	$4M	0.26%	ADD 30%
52	AQR CAPITAL MANAGEMENT LLC	451,185451,185	$3M	0.23%	ADD 123%
53	Universal- Beteiligungs- und Servicegesellschaft mbH	415,458415,458	$3M	0.22%	—
54	WELLINGTON MANAGEMENT GROUP LLP	373,794373,794	$3M	0.19%	ADD 2%
55	Bank of New York Mellon Corp	361,204361,204	$3M	0.19%	ADD 12%
56	Jump Financial, LLC	360,054360,054	$3M	0.19%	ADD 15%
57	Woodline Partners LP	350,531350,531	$3M	0.18%	—
58	TD Asset Management Inc	338,826338,826	$2M	0.18%	ADD 34%
59	Aquatic Capital Management LLC	323,573323,573	$2M	0.17%	NEW
60	HRT FINANCIAL LP	321,376321,376	$2M	0.17%	ADD 7%
61	Newtyn Management, LLC	300,000300,000	$2M	0.16%	—
62	ALLIANCEBERNSTEIN L.P.	125,096125,096	$2M	0.07%	ADD 12%
63	VOLORIDGE INVESTMENT MANAGEMENT, LLC	288,502288,502	$2M	0.15%	TRIM -60%
64	GSA CAPITAL PARTNERS LLP	282,719282,719	$2M	0.15%	NEW
65	BNP PARIBAS FINANCIAL MARKETS	281,023281,023	$2M	0.15%	ADD 243%
66	PLATINUM INVESTMENT MANAGEMENT LTD	275,269275,269	$2M	0.14%	ADD 19%
67	Moody Aldrich Partners LLC	272,533272,533	$2M	0.14%	—
68	SUSQUEHANNA INTERNATIONAL GROUP, LLP	259,825259,825	$2M	0.14%	TRIM -31%
69	Privium Fund Management B.V.	241,010241,010	$2M	0.13%	ADD 25%
70	MANUFACTURERS LIFE INSURANCE COMPANY, THE	240,983240,983	$2M	0.13%	ADD 32%
71	BANK OF AMERICA CORP /DE/	236,760236,760	$2M	0.12%	ADD 29%
72	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	225,114225,114	$2M	0.12%	ADD 36%
73	Swiss National Bank	219,700219,700	$2M	0.11%	—
74	Balyasny Asset Management L.P.	211,074211,074	$2M	0.11%	NEW
75	Scientech Research LLC	200,331200,331	$1M	0.10%	ADD 1186%
76	Invesco Ltd.	199,740199,740	$1M	0.10%	ADD 11%
77	Susquehanna Portfolio Strategies, LLC	195,840195,840	$1M	0.10%	TRIM -15%
78	BARCLAYS PLC	189,865189,865	$1M	0.10%	TRIM -31%
79	Sofinnova Investments, Inc.	189,253189,253	$1M	0.10%	ADD 20%
80	CAPITAL FUND MANAGEMENT S.A.	183,331183,331	$1M	0.10%	NEW
81	Caitong International Asset Management Co., Ltd	180,980180,980	$1M	0.09%	ADD 1647%
82	Elmind Capital, LP	177,846177,846	$1M	0.09%	TRIM -60%
83	Duquesne Family Office LLC	173,000173,000	$1M	0.09%	—
84	RHUMBLINE ADVISERS	167,528167,528	$1M	0.09%	ADD 18%
85	F/m Investments LLC	164,921164,921	$1M	0.09%	TRIM -58%
86	BOOTHBAY FUND MANAGEMENT, LLC	160,311160,311	$1M	0.08%	TRIM -32%
87	Y-Intercept (Hong Kong) Ltd	157,013157,013	$1M	0.08%	NEW
88	Qube Research & Technologies Ltd	155,924155,924	$1M	0.08%	NEW
89	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	150,368150,368	$1M	0.08%	ADD 12%
90	Burkehill Global Management, LP	150,000150,000	$1M	0.08%	—
91	TWINBEECH CAPITAL LP	145,825145,825	$1M	0.08%	NEW
92	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	145,206145,206	$1M	0.08%	ADD 35%
93	Advisory Services Network, LLC	144,950144,950	$1M	0.08%	ADD 594%
94	Capstone Capital Management Ltd	144,029144,029	$1M	0.07%	NEW
95	FRED ALGER MANAGEMENT, LLC	139,218139,218	$1M	0.07%	NEW
96	WELLS FARGO & COMPANY/MN	136,173136,173	$987,255	0.07%	TRIM -32%
97	James J. Burns & Company, LLC	114,800114,800	$832,300	0.06%	ADD 9%
98	DEUTSCHE BANK AG\	114,110114,110	$827,298	0.06%	ADD 19%
99	XTX Topco Ltd	109,862109,862	$796,500	0.06%	NEW
100	STATE OF WISCONSIN INVESTMENT BOARD	108,164108,164	$784,189	0.06%	ADD 24%

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

RA CAPITAL MANAGEMENT, L.P.

18.2M

27.0M

$196M

GSK plc

—

18.2M

$132M

BlackRock, Inc.

9.4M

9.6M

10.4M

12.6M

14.1M

$102M

MAVERICK CAPITAL LTD

8.3M

8.4M

9.3M

10.2M

$74M

PRICE T ROWE ASSOCIATES INC /MD/

5.1M

4.1M

5.2M

4.0M

7.4M

8.7M

$63M

Driehaus Capital Management LLC

6.7M

6.4M

6.5M

6.3M

6.6M

5.4M

$39M

FEDERATED HERMES, INC.

68K

56K

553

3.8M

4.7M

5.3M

$39M

FMR LLC

1.8M

2.1M

619K

5.1M

15.1M

5.2M

$38M

683 Capital Management, LLC

3.8M

3.9M

4.1M

4.2M

4.0M

4.9M

$36M

PRIMECAP MANAGEMENT CO/CA/

2.5M

1.9M

4.1M

4.8M

$35M

M28 Capital Management LP

5.7M

4.6M

$33M

STATE STREET CORP

2.4M

2.8M

3.0M

3.7M

$27M

GEODE CAPITAL MANAGEMENT, LLC

2.5M

2.6M

2.8M

2.9M

3.2M

3.6M

$26M

Siren, L.L.C.

3.8M

3.7M

2.5M

$18M

CITADEL ADVISORS LLC

62K

32K

—

790K

2.2M

$16M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	229	172,603,774	89.7%	$1.2B
2025-Q4	218	182,765,438	95.0%	$3.1B
2025-Q3	189	144,540,375	75.1%	$1.1B
2025-Q2	177	138,966,011	72.2%	$903M
2025-Q1

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · WVE

Activists — 13D, active intent

RA CAPITAL MANAGEMENT, L.P.17.1%▼ -0.4ppSCHEDULE 13D/A · Amd 10 · event 2026-04-15SEC →

34,225,506 shares · 4 reporting persons

Large holders — 13G, passive (top 4 by % of class)

Holder	% of class	Type	As of
BlackRock, Inc.	6.1%	QII	2024-12-31	SEC →
MAVERICK CAPITAL LTD	5.4%	Passive	2024-12-31	SEC →

WVE US Equity☆

Institutional ownership· 13F filers holding WVE · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · WVE

Institutional ownership· 13F filers holding WVE · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · WVE

WVE US Equity