VOR US Equity

Vor Biopharma Inc.

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Health Care · Biological Products, (No Diagnostic Substances) · CIK 1817229 · FYE 1231

$20.00

+0.56 (+2.88%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding VOR · 2026-Q1 methodology → sources →

80 holders

% of shares outstanding held

74.6%

Shares held (13F)

40,448,699

Reporting holders

Top holders

largest 80 of 80 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	TCG Crossover Management, LLC	5,673,0785.7M	$96M	10.47%	NEW†
2	RA CAPITAL MANAGEMENT, L.P.	5,404,9985.4M	$96M	9.97%	—
3	FCPM III SERVICES B.V.	4,117,3544.1M	$73M	7.60%	ADD 14%
4	Venrock Adviser, LLC	3,041,7193.0M	$54M	5.61%	ADD 56%
5	Frazier Life Sciences Management, L.P.	2,543,9392.5M	$45M	4.69%	—
6	Caligan Partners LP	1,925,0661.9M	$34M	3.55%	ADD 108%
7	GREAT POINT PARTNERS LLC	1,750,0001.8M	$31M	3.23%	ADD 28%
8	Paradigm Biocapital Advisors LP	1,750,0001.8M	$31M	3.23%	—
9	FMR LLC	1,539,6701.5M	$27M	2.84%	TRIM -39%
10	VANGUARD CAPITAL MANAGEMENT LLC	1,433,2801.4M	$26M	2.65%	NEW†
11	MARSHALL WACE, LLP	1,153,2761.2M	$21M	2.13%	NEW†
12	STATE STREET CORP	1,118,4581.1M	$20M	2.06%	ADD 1128%
13	NEXTBio Capital Management LP	999,967999,967	$18M	1.85%	—
14	BlackRock, Inc.	794,759794,759	$14M	1.47%	ADD 71%
15	Logos Global Management LP	750,000750,000	$13M	1.38%	ADD 650%
16	Rosalind Advisors, Inc.	700,000700,000	$12M	1.29%	NEW
17	BOOTHBAY FUND MANAGEMENT, LLC	555,702555,702	$10M	1.03%	NEW
18	UBS Group AG	488,368488,368	$9M	0.90%	ADD 67%
19	BRAIDWELL LP	466,774466,774	$8M	0.86%	NEW
20	GEODE CAPITAL MANAGEMENT, LLC	342,573342,573	$6M	0.63%	ADD 84%
21	Clearline Capital LP	326,168326,168	$6M	0.60%	NEW
22	SPHERA FUNDS MANAGEMENT LTD.	321,917321,917	$6M	0.59%	TRIM -22%
23	Laurion Capital Management LP	318,670318,670	$6M	0.59%	—
24	Propel Bio Management, LLC	314,543314,543	$6M	0.58%	NEW
25	GOLDMAN SACHS GROUP INC	261,891261,891	$5M	0.48%	ADD 80%
26	MILLENNIUM MANAGEMENT LLC	258,587258,587	$5M	0.48%	ADD 15%
27	SUSQUEHANNA INTERNATIONAL GROUP, LLP	232,608232,608	$4M	0.43%	ADD 1470%
28	VANGUARD FIDUCIARY TRUST CO	185,511185,511	$3M	0.34%	NEW
29	Jump Financial, LLC	173,028173,028	$3M	0.32%	NEW
30	TUDOR INVESTMENT CORP ET AL	152,571152,571	$3M	0.28%	TRIM -9%
31	CITADEL ADVISORS LLC	148,768148,768	$3M	0.27%	TRIM -66%
32	RENAISSANCE TECHNOLOGIES LLC	128,839128,839	$2M	0.24%	NEW
33	MORGAN STANLEY	116,721116,721	$2M	0.22%	ADD 310%
34	BANK OF AMERICA CORP /DE/	112,892112,892	$2M	0.21%	ADD 28408%
35	AXIOM INVESTORS LLC /DE	95,74595,745	$2M	0.18%	NEW
36	Quadrature Capital Ltd	76,63076,630	$1M	0.14%	ADD 186%
37	JANE STREET GROUP, LLC	75,89075,890	$1M	0.14%	TRIM -17%
38	NORTHERN TRUST CORP	64,54964,549	$1M	0.12%	ADD 66%
39	JOHNSON & JOHNSON	53,73253,732	$958,579	0.10%	—
40	Simplify Asset Management Inc.	53,51053,510	$954,618	0.10%	NEW
41	Rafferty Asset Management, LLC	50,50550,505	$901,009	0.09%	NEW
42	Brevan Howard Capital Management LP	42,21742,217	$753,151	0.08%	NEW
43	Irenic Capital Management LP	32,66332,663	$582,708	0.06%	NEW
44	Engineers Gate Manager LP	26,88026,880	$479,539	0.05%	TRIM -5%
45	Squarepoint Ops LLC	25,48225,482	$454,599	0.05%	ADD 38%
46	Sarissa Capital Management LP	25,39925,399	$453,118	0.05%	—
47	Bollard Group LLC	23,98723,987	$428,000	0.04%	—
48	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	22,21622,216	$396,333	0.04%	NEW
49	PROFUND ADVISORS LLC	22,01522,015	$392,748	0.04%	NEW
50	Scientech Research LLC	15,04715,047	$268,438	0.03%	NEW
51	AXQ CAPITAL, LP	15,01915,019	$267,939	0.03%	NEW
52	INDEPENDENT FINANCIAL GROUP, LLC	13,97513,975	$249,314	0.03%	TRIM -18%
53	SEI INVESTMENTS CO	13,71613,716	$244,529	0.03%	NEW
54	Vanguard Global Advisers, LLC	12,87512,875	$229,690	0.02%	NEW
55	WINTON GROUP Ltd	11,87011,870	$211,761	0.02%	NEW
56	Cannon Global Investment Management, LLC	11,70011,700	$208,728	0.02%	NEW
57	Invesco Ltd.	11,60011,600	$206,944	0.02%	NEW
58	Diametric Capital, LP	10,07010,070	$179,648	0.02%	NEW
59	GROUP ONE TRADING LLC	9,0659,065	$161,720	0.02%	NEW
60	China Universal Asset Management Co., Ltd.	7,3687,368	$131,445	0.01%	ADD 168%
61	CITIGROUP INC	5,3735,373	$95,854	0.01%	TRIM -15%
62	JPMORGAN CHASE & CO	4,3644,364	$64,151	0.01%	ADD 89%
63	Tower Research Capital LLC (TRC)	3,4663,466	$61,833	0.01%	ADD 100%
64	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	3,5133,513	$51,641	0.01%	NEW
65	BNP PARIBAS FINANCIAL MARKETS	2,8442,844	$50,737	0.01%	ADD 877%
66	Mirae Asset Global Investments Co., Ltd.	2,1662,166	$38,641	0.00%	ADD 164%
67	GF FUND MANAGEMENT CO. LTD.	372372	$6,636	0.00%	ADD 13%
68	Quantbot Technologies LP	307307	$5,477	0.00%	NEW
69	PNC FINANCIAL SERVICES GROUP, INC.	246246	$4,389	0.00%	NEW
70	ROYAL BANK OF CANADA	199199	$4,000	0.00%	ADD 2743%
71	BARCLAYS PLC	136136	$2,426	0.00%	TRIM -90%
72	Allworth Financial LP	7373	$1,303	0.00%	ADD 2333%
73	Parallel Advisors, LLC	4848	$856	0.00%	NEW
74	MAI Capital Management	4040	$714	0.00%	—
75	SIGNATUREFD, LLC	3939	$696	0.00%	NEW
76	Ameritas Advisory Services, LLC	3737	$660	0.00%	NEW
77	Fortitude Family Office, LLC	3131	$553	0.00%	NEW
78	WPG Advisers, LLC	2121	$375	0.00%	NEW
79	SBI Securities Co., Ltd.	33	$54	0.00%	—
80	WELLS FARGO & COMPANY/MN	11	$18	0.00%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

TCG Crossover Management, LLC

—

5.7M

$96M

RA CAPITAL MANAGEMENT, L.P.

39.6M

2.0M

5.4M

$96M

FCPM III SERVICES B.V.

—

380K

3.6M

4.1M

$73M

Venrock Adviser, LLC

—

500K

1.9M

3.0M

$54M

Frazier Life Sciences Management, L.P.

—

2.5M

$45M

Caligan Partners LP

—

925K

1.9M

$34M

Paradigm Biocapital Advisors LP

—

1.8M

$31M

GREAT POINT PARTNERS LLC

—

1.4M

1.8M

$31M

FMR LLC

6.4M

2.1M

237K

2.5M

1.5M

$27M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.4M

$26M

MARSHALL WACE, LLP

37K

19K

—

1.2M

$21M

STATE STREET CORP

116K

91K

1.1M

$20M

NEXTBio Capital Management LP

—

1000K

$18M

BlackRock, Inc.

488K

485K

375K

35K

466K

795K

$14M

Logos Global Management LP

—

100K

750K

$13M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	80	40,448,699	74.6%	$717M
2025-Q4	55	25,547,123	47.1%	$332M
2025-Q3	37	3,764,150	6.9%	$183M
2025-Q2	35	57,082,659	105.3%	$92M
2025-Q1	46	60,145,955	—	$43M
2024-Q4	52	60,946,660	—	$68M
2024-Q3	54	47,845,810	88.3%	$33M
2024-Q2	71	54,532,520	100.6%	$55M
2024-Q1	69	59,219,087	109.3%	$140M
2023-Q4	60	59,799,560	—	$135M
2023-Q3	59

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · VOR

Activists — 13D, active intent

RA CAPITAL MANAGEMENT, L.P.19.9%NEWSCHEDULE 13D/A · Amd 18 · event 2026-07-16SEC →

12,937,855 shares · 4 reporting persons

“Item 4 of the Statement is hereby amended and supplemented as follows: Effective July 6, 2026, Andrew Levin resigned from the Board of Directors of the Issuer.”

Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).

Institutional ownership· 13F filers holding VOR · 2026-Q1 methodology → sources →

80 holders

% of shares outstanding held

74.6%

Shares held (13F)

40,448,699

Reporting holders

Top holders

largest 80 of 80 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	TCG Crossover Management, LLC	5,673,0785.7M	$96M	10.47%	NEW†
2	RA CAPITAL MANAGEMENT, L.P.	5,404,9985.4M	$96M	9.97%	—
3	FCPM III SERVICES B.V.	4,117,3544.1M	$73M	7.60%	ADD 14%
4	Venrock Adviser, LLC	3,041,7193.0M	$54M	5.61%	ADD 56%
5	Frazier Life Sciences Management, L.P.	2,543,9392.5M	$45M	4.69%	—
6	Caligan Partners LP	1,925,0661.9M	$34M	3.55%	ADD 108%
7	GREAT POINT PARTNERS LLC	1,750,0001.8M	$31M	3.23%	ADD 28%
8	Paradigm Biocapital Advisors LP	1,750,0001.8M	$31M	3.23%	—
9	FMR LLC	1,539,6701.5M	$27M	2.84%	TRIM -39%
10	VANGUARD CAPITAL MANAGEMENT LLC	1,433,2801.4M	$26M	2.65%	NEW†
11	MARSHALL WACE, LLP	1,153,2761.2M	$21M	2.13%	NEW†
12	STATE STREET CORP	1,118,4581.1M	$20M	2.06%	ADD 1128%
13	NEXTBio Capital Management LP	999,967999,967	$18M	1.85%	—
14	BlackRock, Inc.	794,759794,759	$14M	1.47%	ADD 71%
15	Logos Global Management LP	750,000750,000	$13M	1.38%	ADD 650%
16	Rosalind Advisors, Inc.	700,000700,000	$12M	1.29%	NEW
17	BOOTHBAY FUND MANAGEMENT, LLC	555,702555,702	$10M	1.03%	NEW
18	UBS Group AG	488,368488,368	$9M	0.90%	ADD 67%
19	BRAIDWELL LP	466,774466,774	$8M	0.86%	NEW
20	GEODE CAPITAL MANAGEMENT, LLC	342,573342,573	$6M	0.63%	ADD 84%
21	Clearline Capital LP	326,168326,168	$6M	0.60%	NEW
22	SPHERA FUNDS MANAGEMENT LTD.	321,917321,917	$6M	0.59%	TRIM -22%
23	Laurion Capital Management LP	318,670318,670	$6M	0.59%	—
24	Propel Bio Management, LLC	314,543314,543	$6M	0.58%	NEW
25	GOLDMAN SACHS GROUP INC	261,891261,891	$5M	0.48%	ADD 80%
26	MILLENNIUM MANAGEMENT LLC	258,587258,587	$5M	0.48%	ADD 15%
27	SUSQUEHANNA INTERNATIONAL GROUP, LLP	232,608232,608	$4M	0.43%	ADD 1470%
28	VANGUARD FIDUCIARY TRUST CO	185,511185,511	$3M	0.34%	NEW
29	Jump Financial, LLC	173,028173,028	$3M	0.32%	NEW
30	TUDOR INVESTMENT CORP ET AL	152,571152,571	$3M	0.28%	TRIM -9%
31	CITADEL ADVISORS LLC	148,768148,768	$3M	0.27%	TRIM -66%
32	RENAISSANCE TECHNOLOGIES LLC	128,839128,839	$2M	0.24%	NEW
33	MORGAN STANLEY	116,721116,721	$2M	0.22%	ADD 310%
34	BANK OF AMERICA CORP /DE/	112,892112,892	$2M	0.21%	ADD 28408%
35	AXIOM INVESTORS LLC /DE	95,74595,745	$2M	0.18%	NEW
36	Quadrature Capital Ltd	76,63076,630	$1M	0.14%	ADD 186%
37	JANE STREET GROUP, LLC	75,89075,890	$1M	0.14%	TRIM -17%
38	NORTHERN TRUST CORP	64,54964,549	$1M	0.12%	ADD 66%
39	JOHNSON & JOHNSON	53,73253,732	$958,579	0.10%	—
40	Simplify Asset Management Inc.	53,51053,510	$954,618	0.10%	NEW
41	Rafferty Asset Management, LLC	50,50550,505	$901,009	0.09%	NEW
42	Brevan Howard Capital Management LP	42,21742,217	$753,151	0.08%	NEW
43	Irenic Capital Management LP	32,66332,663	$582,708	0.06%	NEW
44	Engineers Gate Manager LP	26,88026,880	$479,539	0.05%	TRIM -5%
45	Squarepoint Ops LLC	25,48225,482	$454,599	0.05%	ADD 38%
46	Sarissa Capital Management LP	25,39925,399	$453,118	0.05%	—
47	Bollard Group LLC	23,98723,987	$428,000	0.04%	—
48	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	22,21622,216	$396,333	0.04%	NEW
49	PROFUND ADVISORS LLC	22,01522,015	$392,748	0.04%	NEW
50	Scientech Research LLC	15,04715,047	$268,438	0.03%	NEW
51	AXQ CAPITAL, LP	15,01915,019	$267,939	0.03%	NEW
52	INDEPENDENT FINANCIAL GROUP, LLC	13,97513,975	$249,314	0.03%	TRIM -18%
53	SEI INVESTMENTS CO	13,71613,716	$244,529	0.03%	NEW
54	Vanguard Global Advisers, LLC	12,87512,875	$229,690	0.02%	NEW
55	WINTON GROUP Ltd	11,87011,870	$211,761	0.02%	NEW
56	Cannon Global Investment Management, LLC	11,70011,700	$208,728	0.02%	NEW
57	Invesco Ltd.	11,60011,600	$206,944	0.02%	NEW
58	Diametric Capital, LP	10,07010,070	$179,648	0.02%	NEW
59	GROUP ONE TRADING LLC	9,0659,065	$161,720	0.02%	NEW
60	China Universal Asset Management Co., Ltd.	7,3687,368	$131,445	0.01%	ADD 168%
61	CITIGROUP INC	5,3735,373	$95,854	0.01%	TRIM -15%
62	JPMORGAN CHASE & CO	4,3644,364	$64,151	0.01%	ADD 89%
63	Tower Research Capital LLC (TRC)	3,4663,466	$61,833	0.01%	ADD 100%
64	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	3,5133,513	$51,641	0.01%	NEW
65	BNP PARIBAS FINANCIAL MARKETS	2,8442,844	$50,737	0.01%	ADD 877%
66	Mirae Asset Global Investments Co., Ltd.	2,1662,166	$38,641	0.00%	ADD 164%
67	GF FUND MANAGEMENT CO. LTD.	372372	$6,636	0.00%	ADD 13%
68	Quantbot Technologies LP	307307	$5,477	0.00%	NEW
69	PNC FINANCIAL SERVICES GROUP, INC.	246246	$4,389	0.00%	NEW
70	ROYAL BANK OF CANADA	199199	$4,000	0.00%	ADD 2743%
71	BARCLAYS PLC	136136	$2,426	0.00%	TRIM -90%
72	Allworth Financial LP	7373	$1,303	0.00%	ADD 2333%
73	Parallel Advisors, LLC	4848	$856	0.00%	NEW
74	MAI Capital Management	4040	$714	0.00%	—
75	SIGNATUREFD, LLC	3939	$696	0.00%	NEW
76	Ameritas Advisory Services, LLC	3737	$660	0.00%	NEW
77	Fortitude Family Office, LLC	3131	$553	0.00%	NEW
78	WPG Advisers, LLC	2121	$375	0.00%	NEW
79	SBI Securities Co., Ltd.	33	$54	0.00%	—
80	WELLS FARGO & COMPANY/MN	11	$18	0.00%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

TCG Crossover Management, LLC

—

5.7M

$96M

RA CAPITAL MANAGEMENT, L.P.

39.6M

2.0M

5.4M

$96M

FCPM III SERVICES B.V.

—

380K

3.6M

4.1M

$73M

Venrock Adviser, LLC

—

500K

1.9M

3.0M

$54M

Frazier Life Sciences Management, L.P.

—

2.5M

$45M

Caligan Partners LP

—

925K

1.9M

$34M

Paradigm Biocapital Advisors LP

—

1.8M

$31M

GREAT POINT PARTNERS LLC

—

1.4M

1.8M

$31M

FMR LLC

6.4M

2.1M

237K

2.5M

1.5M

$27M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.4M

$26M

MARSHALL WACE, LLP

37K

19K

—

1.2M

$21M

STATE STREET CORP

116K

91K

1.1M

$20M

NEXTBio Capital Management LP

—

1000K

$18M

BlackRock, Inc.

488K

485K

375K

35K

466K

795K

$14M

Logos Global Management LP

—

100K

750K

$13M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	80	40,448,699	74.6%	$717M
2025-Q4	55	25,547,123	47.1%	$332M
2025-Q3	37	3,764,150	6.9%	$183M
2025-Q2	35	57,082,659	105.3%	$92M
2025-Q1	46	60,145,955	—	$43M
2024-Q4	52	60,946,660	—	$68M
2024-Q3	54	47,845,810	88.3%	$33M
2024-Q2	71	54,532,520	100.6%	$55M
2024-Q1	69	59,219,087	109.3%	$140M
2023-Q4	60	59,799,560	—	$135M
2023-Q3	59

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · VOR

Activists — 13D, active intent

RA CAPITAL MANAGEMENT, L.P.19.9%NEWSCHEDULE 13D/A · Amd 18 · event 2026-07-16SEC →

12,937,855 shares · 4 reporting persons

“Item 4 of the Statement is hereby amended and supplemented as follows: Effective July 6, 2026, Andrew Levin resigned from the Board of Directors of the Issuer.”

VOR US Equity☆

Institutional ownership· 13F filers holding VOR · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · VOR

Institutional ownership· 13F filers holding VOR · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · VOR

VOR US Equity