SLDB US Equity

Solid Biosciences Inc.

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Health Care · Biological Products, (No Diagnostic Substances) · CIK 1707502 · FYE 1231

$8.04

+0.07 (+0.88%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding SLDB · 2026-Q1 methodology → sources →

149 holders

% of shares outstanding held

101.5%

Shares held (13F)

99,900,483

Reporting holders

149

Institutional 13F holdings sum to 101.5% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 8,809,823 shares (settlement 2026-04-30) accounts for the excess.

Top holders

largest 100 of 149 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	PERCEPTIVE ADVISORS LLC	11,906,64611.9M	$86M	12.09%	—
2	Bain Capital Life Sciences Investors, LLC	9,808,8199.8M	$71M	9.96%	ADD 24%
3	RA CAPITAL MANAGEMENT, L.P.	9,339,9789.3M	$67M	9.49%	ADD 61%
4	Siren, L.L.C.	7,690,4057.7M	$55M	7.81%	—
5	Vestal Point Capital, LP	5,000,0005.0M	$36M	5.08%	TRIM -14%
6	BlackRock, Inc.	4,958,3545.0M	$36M	5.04%	—
7	JANUS HENDERSON GROUP PLC	4,010,6954.0M	$29M	4.07%	NEW†
8	FMR LLC	3,606,4043.6M	$26M	3.66%	ADD 78%
9	Deep Track Capital, LP	3,565,0623.6M	$26M	3.62%	NEW†
10	ARMISTICE CAPITAL, LLC	3,200,0003.2M	$23M	3.25%	ADD 23%
11	VANGUARD CAPITAL MANAGEMENT LLC	2,674,6242.7M	$19M	2.72%	NEW†
12	CITADEL ADVISORS LLC	2,596,8002.6M	$19M	2.64%	TRIM -3%
13	AMERIPRISE FINANCIAL INC	2,438,8492.4M	$18M	2.48%	NEW†
14	Alyeska Investment Group, L.P.	2,280,1252.3M	$16M	2.32%	ADD 35%
15	FRANKLIN RESOURCES INC	2,192,9372.2M	$16M	2.23%	ADD 37%
16	Point72 Asset Management, L.P.	2,050,8432.1M	$15M	2.08%	TRIM -15%
17	Redmile Group, LLC	2,011,8952.0M	$14M	2.04%	ADD 8%
18	ADAGE CAPITAL PARTNERS GP, L.L.C.	1,756,5061.8M	$13M	1.78%	ADD 25%
19	Monashee Investment Management LLC	1,420,2951.4M	$10M	1.44%	ADD 5%
20	GEODE CAPITAL MANAGEMENT, LLC	1,295,9841.3M	$9M	1.32%	ADD 2%
21	Nantahala Capital Management, LLC	1,165,0781.2M	$8M	1.18%	TRIM -27%
22	STATE STREET CORP	1,125,4871.1M	$8M	1.14%	ADD 4%
23	DIMENSIONAL FUND ADVISORS LP	956,135956,135	$7M	0.97%	ADD 41%
24	GOLDMAN SACHS GROUP INC	935,535935,535	$7M	0.95%	TRIM -7%
25	Ally Bridge Group (NY) LLC	766,974766,974	$6M	0.78%	ADD 85%
26	BLAIR WILLIAM & CO/IL	651,216651,216	$5M	0.66%	NEW
27	Birchview Capital, LP	625,980625,980	$5M	0.64%	TRIM -11%
28	Woodline Partners LP	495,076495,076	$4M	0.50%	ADD 56%
29	NORTHERN TRUST CORP	418,199418,199	$3M	0.42%	—
30	Nuveen, LLC	400,292400,292	$3M	0.41%	—
31	STEMPOINT CAPITAL LP	390,806390,806	$3M	0.40%	NEW
32	BANK OF AMERICA CORP /DE/	386,793386,793	$3M	0.39%	ADD 12%
33	MILLENNIUM MANAGEMENT LLC	363,675363,675	$3M	0.37%	ADD 212%
34	Invesco Ltd.	340,940340,940	$2M	0.35%	ADD 124%
35	VANGUARD PORTFOLIO MANAGEMENT LLC	338,630338,630	$2M	0.34%	NEW
36	VANGUARD FIDUCIARY TRUST CO	325,979325,979	$2M	0.33%	NEW
37	MOORE CAPITAL MANAGEMENT, LP	324,749324,749	$2M	0.33%	NEW
38	Parkman Healthcare Partners LLC	308,844308,844	$2M	0.31%	TRIM -26%
39	Boxer Capital Management, LLC	300,000300,000	$2M	0.30%	—
40	J. Goldman & Co LP	284,467284,467	$2M	0.29%	NEW
41	SUSQUEHANNA INTERNATIONAL GROUP, LLP	269,731269,731	$2M	0.27%	TRIM -46%
42	Ikarian Capital, LLC	264,409264,409	$2M	0.27%	ADD 65%
43	MORGAN STANLEY	261,130261,130	$2M	0.27%	TRIM -34%
44	JPMORGAN CHASE & CO	276,412276,412	$2M	0.28%	ADD 770%
45	BNP PARIBAS FINANCIAL MARKETS	217,196217,196	$2M	0.22%	ADD 191%
46	Susquehanna Portfolio Strategies, LLC	197,571197,571	$1M	0.20%	—
47	Balyasny Asset Management L.P.	178,253178,253	$1M	0.18%	TRIM -51%
48	WELLINGTON MANAGEMENT GROUP LLP	161,278161,278	$1M	0.16%	TRIM -13%
49	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	160,730160,730	$1M	0.16%	—
50	Apis Capital Advisors, LLC	160,000160,000	$1M	0.16%	TRIM -18%
51	AQR CAPITAL MANAGEMENT LLC	151,541151,541	$1M	0.15%	ADD 15%
52	Bank of New York Mellon Corp	137,944137,944	$993,194	0.14%	TRIM -5%
53	D. E. Shaw & Co., Inc.	128,348128,348	$924,106	0.13%	—
54	RENAISSANCE TECHNOLOGIES LLC	124,272124,272	$894,758	0.13%	ADD 135%
55	Trexquant Investment LP	123,906123,906	$892,123	0.13%	NEW
56	AMERICAN CENTURY COMPANIES INC	114,392114,392	$823,622	0.12%	ADD 18%
57	Fisher Asset Management, LLC	103,481103,481	$745,063	0.11%	—
58	UBS Group AG	98,97898,978	$712,642	0.10%	TRIM -89%
59	JANE STREET GROUP, LLC	96,99396,993	$698,349	0.10%	TRIM -55%
60	TWO SIGMA INVESTMENTS, LP	92,20792,207	$663,890	0.09%	TRIM -40%
61	PANAGORA ASSET MANAGEMENT INC	91,09591,095	$655,884	0.09%	TRIM -60%
62	Quantum Private Wealth, LLC	90,23190,231	$649,663	0.09%	TRIM -4%
63	BOOTHBAY FUND MANAGEMENT, LLC	87,04987,049	$626,753	0.09%	ADD 65%
64	HRT FINANCIAL LP	86,90586,905	$625,000	0.09%	ADD 483%
65	RHUMBLINE ADVISERS	82,10382,103	$591,142	0.08%	—
66	XTX Topco Ltd	76,48576,485	$550,692	0.08%	ADD 115%
67	ALGERT GLOBAL LLC	72,65472,654	$523,000	0.07%	NEW
68	CITIGROUP INC	69,37669,376	$499,507	0.07%	ADD 1878%
69	Virtu Financial LLC	59,73959,739	$430,000	0.06%	NEW
70	BARCLAYS PLC	58,87758,877	$423,915	0.06%	TRIM -57%
71	ALLIANCEBERNSTEIN L.P.	69,26069,260	$390,626	0.07%	TRIM -15%
72	Knott David M Jr	47,14347,143	$339,430	0.05%	TRIM -71%
73	DEUTSCHE BANK AG\	46,27546,275	$333,180	0.05%	ADD 16%
74	STATE OF WISCONSIN INVESTMENT BOARD	45,60745,607	$328,370	0.05%	ADD 52%
75	Squarepoint Ops LLC	44,76944,769	$322,337	0.05%	TRIM -11%
76	PRICE T ROWE ASSOCIATES INC /MD/	40,34740,347	$291,000	0.04%	ADD 15%
77	HSBC HOLDINGS PLC	39,51139,511	$284,479	0.04%	TRIM -11%
78	LOS ANGELES CAPITAL MANAGEMENT LLC	37,42037,420	$269,424	0.04%	NEW
79	Vanguard Global Advisers, LLC	36,40236,402	$262,094	0.04%	NEW
80	Creative Planning	34,56634,566	$248,875	0.04%	ADD 39%
81	CIBC Bancorp USA Inc.	33,56933,569	$241,697	0.03%	NEW
82	WELLS FARGO & COMPANY/MN	32,28132,281	$232,423	0.03%	TRIM -58%
83	Schonfeld Strategic Advisors LLC	30,49330,493	$219,549	0.03%	TRIM -83%
84	GSA CAPITAL PARTNERS LLP	29,56929,569	$213,000	0.03%	NEW
85	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	28,02428,024	$201,773	0.03%	ADD 2%
86	Persistent Asset Partners Ltd	27,99027,990	$201,528	0.03%	NEW
87	MetLife Investment Management, LLC	26,48326,483	$190,678	0.03%	TRIM -20%
88	Brooklyn Investment Group	25,81125,811	$185,840	0.03%	NEW
89	FOX RUN MANAGEMENT, L.L.C.	27,22827,228	$176,710	0.03%	ADD 9%
90	BRIDGEWAY CAPITAL MANAGEMENT, LLC	23,46023,460	$168,912	0.02%	—
91	SFMG, LLC	22,15322,153	$159,502	0.02%	NEW
92	Engineers Gate Manager LP	21,50521,505	$154,836	0.02%	NEW
93	Scientech Research LLC	20,40920,409	$146,945	0.02%	NEW
94	MIRABELLA FINANCIAL SERVICES LLP	19,89719,897	$143,258	0.02%	NEW
95	Police & Firemen's Retirement System of New Jersey	17,38917,389	$125,201	0.02%	—
96	INTECH INVESTMENT MANAGEMENT LLC	16,57816,578	$119,362	0.02%	TRIM -52%
97	MANUFACTURERS LIFE INSURANCE COMPANY, THE	16,27316,273	$117,166	0.02%	TRIM -11%
98	Lido Advisors, LLC	16,00016,000	$115,200	0.02%	TRIM -21%
99	SIMPLEX TRADING, LLC	15,09715,097	$108,698	0.02%	TRIM -75%
100	Verdad Advisers, LP	14,87914,879	$107,129	0.02%	NEW

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

PERCEPTIVE ADVISORS LLC

6.9M

11.9M

11.8M

11.9M

$86M

Bain Capital Life Sciences Investors, LLC

4.0M

7.9M

9.8M

$71M

RA CAPITAL MANAGEMENT, L.P.

4.3M

5.8M

9.3M

$67M

Siren, L.L.C.

3.7M

7.4M

7.7M

$55M

Vestal Point Capital, LP

2.9M

1.8M

1.5M

3.0M

5.8M

5.0M

$36M

BlackRock, Inc.

1.9M

2.2M

4.9M

4.7M

4.9M

5.0M

$36M

JANUS HENDERSON GROUP PLC

—

4.0M

$29M

FMR LLC

47K

3.5M

3.2M

2.9M

2.0M

3.6M

$26M

Deep Track Capital, LP

—

3.6M

$26M

ARMISTICE CAPITAL, LLC

—

400K

936K

2.6M

3.2M

$23M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.7M

$19M

CITADEL ADVISORS LLC

948K

1.9M

2.5M

2.6M

2.7M

2.6M

$19M

AMERIPRISE FINANCIAL INC

—

2.4M

$18M

Alyeska Investment Group, L.P.

346K

1.6M

1.7M

2.3M

$16M

FRANKLIN RESOURCES INC

—

1.2M

1.6M

2.2M

$16M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	149	99,900,483	101.5%	$719M
2025-Q4	131	81,430,609	82.7%	$459M
2025-Q3	129	81,927,175	83.2%	$505M
2025-Q2	116	83,215,566	84.5%	$405M
2025-Q1	125	79,202,748	80.5%	$293M
2024-Q4	90	36,331,913	36.9%	$145M
2024-Q3	92	35,855,143	36.4%

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · SLDB

Activists — 13D, active intent

PERCEPTIVE ADVISORS LLC12.9%▼ -2.7ppSCHEDULE 13D/A · Amd 9 · event 2026-03-09SEC →

11,969,079 shares · 4 reporting persons

“The information set forth in Item 6 below in this Amendment No. 9 to Schedule 13D is incorporated by reference.”

RA CAPITAL MANAGEMENT, L.P.11.9%▲ +2ppSCHEDULE 13D/A · Amd 13 · event 2026-06-22SEC →

12,036,126 shares · 4 reporting persons

BCLS SB Investco, LP8.8%▲ +1ppSCHEDULE 13D/A · Amd 11 · event 2026-03-06SEC →

8,604,852 shares · 6 reporting persons

Large holders — 13G, passive (top 5 of 6 by % of class)

Holder

% of class

Type

As of

Invus Global Management, LLC

Institutional ownership· 13F filers holding SLDB · 2026-Q1 methodology → sources →

149 holders

% of shares outstanding held

101.5%

Shares held (13F)

99,900,483

Reporting holders

149

Top holders

largest 100 of 149 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	PERCEPTIVE ADVISORS LLC	11,906,64611.9M	$86M	12.09%	—
2	Bain Capital Life Sciences Investors, LLC	9,808,8199.8M	$71M	9.96%	ADD 24%
3	RA CAPITAL MANAGEMENT, L.P.	9,339,9789.3M	$67M	9.49%	ADD 61%
4	Siren, L.L.C.	7,690,4057.7M	$55M	7.81%	—
5	Vestal Point Capital, LP	5,000,0005.0M	$36M	5.08%	TRIM -14%
6	BlackRock, Inc.	4,958,3545.0M	$36M	5.04%	—
7	JANUS HENDERSON GROUP PLC	4,010,6954.0M	$29M	4.07%	NEW†
8	FMR LLC	3,606,4043.6M	$26M	3.66%	ADD 78%
9	Deep Track Capital, LP	3,565,0623.6M	$26M	3.62%	NEW†
10	ARMISTICE CAPITAL, LLC	3,200,0003.2M	$23M	3.25%	ADD 23%
11	VANGUARD CAPITAL MANAGEMENT LLC	2,674,6242.7M	$19M	2.72%	NEW†
12	CITADEL ADVISORS LLC	2,596,8002.6M	$19M	2.64%	TRIM -3%
13	AMERIPRISE FINANCIAL INC	2,438,8492.4M	$18M	2.48%	NEW†
14	Alyeska Investment Group, L.P.	2,280,1252.3M	$16M	2.32%	ADD 35%
15	FRANKLIN RESOURCES INC	2,192,9372.2M	$16M	2.23%	ADD 37%
16	Point72 Asset Management, L.P.	2,050,8432.1M	$15M	2.08%	TRIM -15%
17	Redmile Group, LLC	2,011,8952.0M	$14M	2.04%	ADD 8%
18	ADAGE CAPITAL PARTNERS GP, L.L.C.	1,756,5061.8M	$13M	1.78%	ADD 25%
19	Monashee Investment Management LLC	1,420,2951.4M	$10M	1.44%	ADD 5%
20	GEODE CAPITAL MANAGEMENT, LLC	1,295,9841.3M	$9M	1.32%	ADD 2%
21	Nantahala Capital Management, LLC	1,165,0781.2M	$8M	1.18%	TRIM -27%
22	STATE STREET CORP	1,125,4871.1M	$8M	1.14%	ADD 4%
23	DIMENSIONAL FUND ADVISORS LP	956,135956,135	$7M	0.97%	ADD 41%
24	GOLDMAN SACHS GROUP INC	935,535935,535	$7M	0.95%	TRIM -7%
25	Ally Bridge Group (NY) LLC	766,974766,974	$6M	0.78%	ADD 85%
26	BLAIR WILLIAM & CO/IL	651,216651,216	$5M	0.66%	NEW
27	Birchview Capital, LP	625,980625,980	$5M	0.64%	TRIM -11%
28	Woodline Partners LP	495,076495,076	$4M	0.50%	ADD 56%
29	NORTHERN TRUST CORP	418,199418,199	$3M	0.42%	—
30	Nuveen, LLC	400,292400,292	$3M	0.41%	—
31	STEMPOINT CAPITAL LP	390,806390,806	$3M	0.40%	NEW
32	BANK OF AMERICA CORP /DE/	386,793386,793	$3M	0.39%	ADD 12%
33	MILLENNIUM MANAGEMENT LLC	363,675363,675	$3M	0.37%	ADD 212%
34	Invesco Ltd.	340,940340,940	$2M	0.35%	ADD 124%
35	VANGUARD PORTFOLIO MANAGEMENT LLC	338,630338,630	$2M	0.34%	NEW
36	VANGUARD FIDUCIARY TRUST CO	325,979325,979	$2M	0.33%	NEW
37	MOORE CAPITAL MANAGEMENT, LP	324,749324,749	$2M	0.33%	NEW
38	Parkman Healthcare Partners LLC	308,844308,844	$2M	0.31%	TRIM -26%
39	Boxer Capital Management, LLC	300,000300,000	$2M	0.30%	—
40	J. Goldman & Co LP	284,467284,467	$2M	0.29%	NEW
41	SUSQUEHANNA INTERNATIONAL GROUP, LLP	269,731269,731	$2M	0.27%	TRIM -46%
42	Ikarian Capital, LLC	264,409264,409	$2M	0.27%	ADD 65%
43	MORGAN STANLEY	261,130261,130	$2M	0.27%	TRIM -34%
44	JPMORGAN CHASE & CO	276,412276,412	$2M	0.28%	ADD 770%
45	BNP PARIBAS FINANCIAL MARKETS	217,196217,196	$2M	0.22%	ADD 191%
46	Susquehanna Portfolio Strategies, LLC	197,571197,571	$1M	0.20%	—
47	Balyasny Asset Management L.P.	178,253178,253	$1M	0.18%	TRIM -51%
48	WELLINGTON MANAGEMENT GROUP LLP	161,278161,278	$1M	0.16%	TRIM -13%
49	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	160,730160,730	$1M	0.16%	—
50	Apis Capital Advisors, LLC	160,000160,000	$1M	0.16%	TRIM -18%
51	AQR CAPITAL MANAGEMENT LLC	151,541151,541	$1M	0.15%	ADD 15%
52	Bank of New York Mellon Corp	137,944137,944	$993,194	0.14%	TRIM -5%
53	D. E. Shaw & Co., Inc.	128,348128,348	$924,106	0.13%	—
54	RENAISSANCE TECHNOLOGIES LLC	124,272124,272	$894,758	0.13%	ADD 135%
55	Trexquant Investment LP	123,906123,906	$892,123	0.13%	NEW
56	AMERICAN CENTURY COMPANIES INC	114,392114,392	$823,622	0.12%	ADD 18%
57	Fisher Asset Management, LLC	103,481103,481	$745,063	0.11%	—
58	UBS Group AG	98,97898,978	$712,642	0.10%	TRIM -89%
59	JANE STREET GROUP, LLC	96,99396,993	$698,349	0.10%	TRIM -55%
60	TWO SIGMA INVESTMENTS, LP	92,20792,207	$663,890	0.09%	TRIM -40%
61	PANAGORA ASSET MANAGEMENT INC	91,09591,095	$655,884	0.09%	TRIM -60%
62	Quantum Private Wealth, LLC	90,23190,231	$649,663	0.09%	TRIM -4%
63	BOOTHBAY FUND MANAGEMENT, LLC	87,04987,049	$626,753	0.09%	ADD 65%
64	HRT FINANCIAL LP	86,90586,905	$625,000	0.09%	ADD 483%
65	RHUMBLINE ADVISERS	82,10382,103	$591,142	0.08%	—
66	XTX Topco Ltd	76,48576,485	$550,692	0.08%	ADD 115%
67	ALGERT GLOBAL LLC	72,65472,654	$523,000	0.07%	NEW
68	CITIGROUP INC	69,37669,376	$499,507	0.07%	ADD 1878%
69	Virtu Financial LLC	59,73959,739	$430,000	0.06%	NEW
70	BARCLAYS PLC	58,87758,877	$423,915	0.06%	TRIM -57%
71	ALLIANCEBERNSTEIN L.P.	69,26069,260	$390,626	0.07%	TRIM -15%
72	Knott David M Jr	47,14347,143	$339,430	0.05%	TRIM -71%
73	DEUTSCHE BANK AG\	46,27546,275	$333,180	0.05%	ADD 16%
74	STATE OF WISCONSIN INVESTMENT BOARD	45,60745,607	$328,370	0.05%	ADD 52%
75	Squarepoint Ops LLC	44,76944,769	$322,337	0.05%	TRIM -11%
76	PRICE T ROWE ASSOCIATES INC /MD/	40,34740,347	$291,000	0.04%	ADD 15%
77	HSBC HOLDINGS PLC	39,51139,511	$284,479	0.04%	TRIM -11%
78	LOS ANGELES CAPITAL MANAGEMENT LLC	37,42037,420	$269,424	0.04%	NEW
79	Vanguard Global Advisers, LLC	36,40236,402	$262,094	0.04%	NEW
80	Creative Planning	34,56634,566	$248,875	0.04%	ADD 39%
81	CIBC Bancorp USA Inc.	33,56933,569	$241,697	0.03%	NEW
82	WELLS FARGO & COMPANY/MN	32,28132,281	$232,423	0.03%	TRIM -58%
83	Schonfeld Strategic Advisors LLC	30,49330,493	$219,549	0.03%	TRIM -83%
84	GSA CAPITAL PARTNERS LLP	29,56929,569	$213,000	0.03%	NEW
85	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	28,02428,024	$201,773	0.03%	ADD 2%
86	Persistent Asset Partners Ltd	27,99027,990	$201,528	0.03%	NEW
87	MetLife Investment Management, LLC	26,48326,483	$190,678	0.03%	TRIM -20%
88	Brooklyn Investment Group	25,81125,811	$185,840	0.03%	NEW
89	FOX RUN MANAGEMENT, L.L.C.	27,22827,228	$176,710	0.03%	ADD 9%
90	BRIDGEWAY CAPITAL MANAGEMENT, LLC	23,46023,460	$168,912	0.02%	—
91	SFMG, LLC	22,15322,153	$159,502	0.02%	NEW
92	Engineers Gate Manager LP	21,50521,505	$154,836	0.02%	NEW
93	Scientech Research LLC	20,40920,409	$146,945	0.02%	NEW
94	MIRABELLA FINANCIAL SERVICES LLP	19,89719,897	$143,258	0.02%	NEW
95	Police & Firemen's Retirement System of New Jersey	17,38917,389	$125,201	0.02%	—
96	INTECH INVESTMENT MANAGEMENT LLC	16,57816,578	$119,362	0.02%	TRIM -52%
97	MANUFACTURERS LIFE INSURANCE COMPANY, THE	16,27316,273	$117,166	0.02%	TRIM -11%
98	Lido Advisors, LLC	16,00016,000	$115,200	0.02%	TRIM -21%
99	SIMPLEX TRADING, LLC	15,09715,097	$108,698	0.02%	TRIM -75%
100	Verdad Advisers, LP	14,87914,879	$107,129	0.02%	NEW

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

PERCEPTIVE ADVISORS LLC

6.9M

11.9M

11.8M

11.9M

$86M

Bain Capital Life Sciences Investors, LLC

4.0M

7.9M

9.8M

$71M

RA CAPITAL MANAGEMENT, L.P.

4.3M

5.8M

9.3M

$67M

Siren, L.L.C.

3.7M

7.4M

7.7M

$55M

Vestal Point Capital, LP

2.9M

1.8M

1.5M

3.0M

5.8M

5.0M

$36M

BlackRock, Inc.

1.9M

2.2M

4.9M

4.7M

4.9M

5.0M

$36M

JANUS HENDERSON GROUP PLC

—

4.0M

$29M

FMR LLC

47K

3.5M

3.2M

2.9M

2.0M

3.6M

$26M

Deep Track Capital, LP

—

3.6M

$26M

ARMISTICE CAPITAL, LLC

—

400K

936K

2.6M

3.2M

$23M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.7M

$19M

CITADEL ADVISORS LLC

948K

1.9M

2.5M

2.6M

2.7M

2.6M

$19M

AMERIPRISE FINANCIAL INC

—

2.4M

$18M

Alyeska Investment Group, L.P.

346K

1.6M

1.7M

2.3M

$16M

FRANKLIN RESOURCES INC

—

1.2M

1.6M

2.2M

$16M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	149	99,900,483	101.5%	$719M
2025-Q4	131	81,430,609	82.7%	$459M
2025-Q3	129	81,927,175	83.2%	$505M
2025-Q2	116	83,215,566	84.5%	$405M
2025-Q1	125	79,202,748	80.5%	$293M
2024-Q4	90	36,331,913	36.9%	$145M
2024-Q3	92	35,855,143	36.4%

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · SLDB

Activists — 13D, active intent

PERCEPTIVE ADVISORS LLC12.9%▼ -2.7ppSCHEDULE 13D/A · Amd 9 · event 2026-03-09SEC →

11,969,079 shares · 4 reporting persons

“The information set forth in Item 6 below in this Amendment No. 9 to Schedule 13D is incorporated by reference.”

RA CAPITAL MANAGEMENT, L.P.11.9%▲ +2ppSCHEDULE 13D/A · Amd 13 · event 2026-06-22SEC →

12,036,126 shares · 4 reporting persons

BCLS SB Investco, LP8.8%▲ +1ppSCHEDULE 13D/A · Amd 11 · event 2026-03-06SEC →

8,604,852 shares · 6 reporting persons

Large holders — 13G, passive (top 5 of 6 by % of class)

Holder

% of class

Type

As of

Invus Global Management, LLC

SLDB US Equity☆

Institutional ownership· 13F filers holding SLDB · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · SLDB

Institutional ownership· 13F filers holding SLDB · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · SLDB

SLDB US Equity