AXSM US Equity

Axsome Therapeutics, Inc.

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Health Care · Pharmaceutical Preparations · CIK 1579428 · FYE 1231

$227.42

-6.78 (-2.89%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding AXSM · 2026-Q1 methodology → sources →

408 holders

% of shares outstanding held

73.7%

Shares held (13F)

37,911,100

Reporting holders

408

Top holders

largest 100 of 408 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	3,912,8443.9M	$661M	7.60%	—
2	VANGUARD PORTFOLIO MANAGEMENT LLC	2,058,1702.1M	$348M	4.00%	NEW†
3	VANGUARD CAPITAL MANAGEMENT LLC	1,937,7521.9M	$328M	3.77%	NEW†
4	FMR LLC	1,566,9951.6M	$265M	3.05%	ADD 33%
5	PRICE T ROWE ASSOCIATES INC /MD/	1,317,0591.3M	$223M	2.56%	TRIM -13%
6	Invesco Ltd.	1,297,6781.3M	$219M	2.52%	—
7	GEODE CAPITAL MANAGEMENT, LLC	1,162,9811.2M	$197M	2.26%	ADD 15%
8	WELLINGTON MANAGEMENT GROUP LLP	1,145,3061.1M	$194M	2.23%	TRIM -6%
9	Deep Track Capital, LP	1,100,0001.1M	$186M	2.14%	TRIM -4%
10	STATE STREET CORP	986,809986,809	$167M	1.92%	ADD 3%
11	Assenagon Asset Management S.A.	865,958865,958	$146M	1.68%	ADD 85%
12	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	812,809812,809	$137M	1.58%	TRIM -18%
13	ADAGE CAPITAL PARTNERS GP, L.L.C.	737,578737,578	$125M	1.43%	ADD 101%
14	ALETHEA CAPITAL MANAGEMENT, LLC	649,114649,114	$110M	1.26%	TRIM -3%
15	D. E. Shaw & Co., Inc.	603,465603,465	$102M	1.17%	ADD 10%
16	BANK OF AMERICA CORP /DE/	598,091598,091	$101M	1.16%	TRIM -3%
17	FIRST TRUST ADVISORS LP	577,479577,479	$98M	1.12%	ADD 1230%
18	UBS Group AG	547,195547,195	$92M	1.06%	ADD 54%
19	EVENTIDE ASSET MANAGEMENT, LLC	519,558519,558	$88M	1.01%	TRIM -9%
20	MORGAN STANLEY	476,701476,701	$81M	0.93%	TRIM -3%
21	FRANKLIN RESOURCES INC	438,490438,490	$74M	0.85%	ADD 28%
22	Point72 Asset Management, L.P.	424,750424,750	$72M	0.83%	ADD 2260%
23	GOLDMAN SACHS GROUP INC	421,447421,447	$71M	0.82%	ADD 40%
24	Pictet Asset Management Holding SA	415,983415,983	$70M	0.81%	TRIM -5%
25	NORTHERN TRUST CORP	401,459401,459	$68M	0.78%	ADD 3%
26	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	395,118395,118	$67M	0.77%	—
27	Hood River Capital Management LLC	371,503371,503	$63M	0.72%	—
28	PRINCIPAL FINANCIAL GROUP INC	350,488350,488	$59M	0.68%	TRIM -3%
29	Nuveen, LLC	335,737335,737	$57M	0.65%	TRIM -4%
30	Qube Research & Technologies Ltd	335,334335,334	$57M	0.65%	ADD 3%
31	TWO SIGMA INVESTMENTS, LP	322,778322,778	$55M	0.63%	ADD 122%
32	VANGUARD FIDUCIARY TRUST CO	295,139295,139	$50M	0.57%	NEW
33	Driehaus Capital Management LLC	292,370292,370	$49M	0.57%	ADD 33%
34	CITADEL ADVISORS LLC	281,503281,503	$48M	0.55%	ADD 104%
35	PFM Health Sciences, LP	264,304264,304	$45M	0.51%	ADD 5%
36	LOOMIS SAYLES & CO L P	256,625256,625	$43M	0.50%	TRIM -19%
37	JPMORGAN CHASE & CO	270,160270,160	$43M	0.52%	ADD 16%
38	ORBIMED ADVISORS LLC	213,921213,921	$36M	0.42%	TRIM -15%
39	Sofinnova Investments, Inc.	212,747212,747	$36M	0.41%	ADD 1634%
40	Bank of New York Mellon Corp	206,644206,644	$35M	0.40%	TRIM -19%
41	FRONTIER CAPITAL MANAGEMENT CO LLC	203,066203,066	$34M	0.39%	ADD 29%
42	First Turn Management, LLC	188,772188,772	$32M	0.37%	TRIM -9%
43	BNP PARIBAS FINANCIAL MARKETS	188,146188,146	$32M	0.37%	TRIM -38%
44	CITIGROUP INC	185,658185,658	$31M	0.36%	TRIM -9%
45	VOYA INVESTMENT MANAGEMENT LLC	183,967183,967	$31M	0.36%	ADD 6%
46	AMERIPRISE FINANCIAL INC	176,314176,314	$30M	0.34%	ADD 76%
47	RENAISSANCE TECHNOLOGIES LLC	164,300164,300	$28M	0.32%	TRIM -3%
48	Woodline Partners LP	162,221162,221	$27M	0.32%	ADD 8%
49	MetLife Investment Management, LLC	152,645152,645	$26M	0.30%	TRIM -7%
50	PERCEPTIVE ADVISORS LLC	149,950149,950	$25M	0.29%	—
51	Aberdeen Group plc	149,688149,688	$25M	0.29%	ADD 54%
52	Voleon Capital Management LP	147,867147,867	$25M	0.29%	ADD 34%
53	RAYMOND JAMES FINANCIAL INC	147,766147,766	$24M	0.29%	—
54	1832 Asset Management L.P.	143,800143,800	$24M	0.28%	ADD 950%
55	Man Group plc	142,271142,271	$24M	0.28%	TRIM -38%
56	MARSHALL WACE, LLP	141,236141,236	$24M	0.27%	TRIM -56%
57	ALGERT GLOBAL LLC	135,460135,460	$23M	0.26%	TRIM -9%
58	Connor, Clark & Lunn Investment Management Ltd.	134,792134,792	$23M	0.26%	TRIM -28%
59	US BANCORP \DE\	131,414131,414	$22M	0.26%	—
60	MANUFACTURERS LIFE INSURANCE COMPANY, THE	117,093117,093	$20M	0.23%	TRIM -13%
61	Squarepoint Ops LLC	114,102114,102	$19M	0.22%	TRIM -26%
62	FEDERATED HERMES, INC.	108,571108,571	$18M	0.21%	ADD 24%
63	EMERALD ADVISERS, LLC	107,610107,610	$18M	0.21%	—
64	DEUTSCHE BANK AG\	104,266104,266	$18M	0.20%	ADD 6%
65	AQR CAPITAL MANAGEMENT LLC	104,059104,059	$18M	0.20%	—
66	WCM INVESTMENT MANAGEMENT, LLC	107,817107,817	$17M	0.21%	TRIM -4%
67	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	97,55097,550	$16M	0.19%	NEW
68	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	94,93794,937	$16M	0.18%	ADD 9%
69	ROYCE & ASSOCIATES LP	94,01794,017	$16M	0.18%	—
70	CANADA PENSION PLAN INVESTMENT BOARD	91,40091,400	$15M	0.18%	TRIM -11%
71	M&G PLC	91,33991,339	$15M	0.18%	—
72	DNB Asset Management AS	90,08890,088	$15M	0.18%	TRIM -11%
73	Cannell & Spears LLC	84,15484,154	$14M	0.16%	—
74	Nicholas Investment Partners, LP	81,47881,478	$14M	0.16%	TRIM -11%
75	Granite Investment Partners, LLC	80,29980,299	$14M	0.16%	TRIM -5%
76	Universal- Beteiligungs- und Servicegesellschaft mbH	70,72570,725	$12M	0.14%	ADD 3%
77	SEI INVESTMENTS CO	70,06470,064	$12M	0.14%	ADD 47%
78	Swiss National Bank	69,10069,100	$12M	0.13%	—
79	HSBC HOLDINGS PLC	68,45368,453	$12M	0.13%	NEW
80	ALLIANCEBERNSTEIN L.P.	62,82262,822	$11M	0.12%	ADD 18%
81	IRIDIAN ASSET MANAGEMENT LLC/CT	67,49167,491	$11M	0.13%	TRIM -9%
82	EMERALD MUTUAL FUND ADVISERS TRUST	67,05467,054	$11M	0.13%	—
83	Summit Financial, LLC	65,24965,249	$11M	0.13%	TRIM -8%
84	Rhenman & Partners Asset Management AB	63,80063,800	$11M	0.12%	TRIM -44%
85	Tri Locum Partners LP	62,11662,116	$10M	0.12%	TRIM -69%
86	WELLS FARGO & COMPANY/MN	61,40561,405	$10M	0.12%	TRIM -32%
87	IFP Advisors, Inc	60,99460,994	$10M	0.12%	TRIM -2%
88	NEUBERGER BERMAN GROUP LLC	60,75960,759	$10M	0.12%	TRIM -13%
89	Privium Fund Management B.V.	58,72958,729	$10M	0.11%	ADD 3%
90	Bridgewater Associates, LP	56,95156,951	$10M	0.11%	ADD 20%
91	HighTower Advisors, LLC	56,63356,633	$10M	0.11%	—
92	AXIOM INVESTORS LLC /DE	56,52956,529	$10M	0.11%	TRIM -11%
93	Hillsdale Investment Management Inc.	53,36353,363	$9M	0.10%	NEW
94	RHUMBLINE ADVISERS	51,61951,619	$9M	0.10%	—
95	California Public Employees Retirement System	50,87950,879	$9M	0.10%	NEW
96	HB Wealth Management, LLC	50,23750,237	$8M	0.10%	ADD 47%
97	NEW YORK STATE COMMON RETIREMENT FUND	50,11350,113	$8M	0.10%	ADD 18%
98	Cormorant Asset Management, LP	50,00050,000	$8M	0.10%	TRIM -33%
99	PEREGRINE CAPITAL MANAGEMENT LLC	47,29647,296	$8M	0.09%	—
100	SUSQUEHANNA INTERNATIONAL GROUP, LLP	47,19847,198	$8M	0.09%	ADD 58%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

3.5M

3.8M

3.9M

$661M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

2.1M

$348M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.9M

$328M

FMR LLC

1.0M

1.2M

977K

928K

1.2M

1.6M

$265M

PRICE T ROWE ASSOCIATES INC /MD/

31K

32K

613K

1.0M

1.5M

1.3M

$223M

Invesco Ltd.

692K

857K

572K

991K

1.3M

$219M

GEODE CAPITAL MANAGEMENT, LLC

913K

935K

989K

998K

1.0M

1.2M

$197M

WELLINGTON MANAGEMENT GROUP LLP

673K

703K

725K

1.3M

1.2M

1.1M

$194M

Deep Track Capital, LP

—

801K

900K

1.1M

$186M

STATE STREET CORP

947K

906K

959K

943K

958K

987K

$167M

Assenagon Asset Management S.A.

627K

181K

295K

468K

866K

$146M

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

—

989K

813K

$137M

ADAGE CAPITAL PARTNERS GP, L.L.C.

60K

48K

447K

445K

368K

738K

$125M

ALETHEA CAPITAL MANAGEMENT, LLC

734K

667K

671K

669K

649K

$110M

D. E. Shaw & Co., Inc.

20K

548K

201K

296K

549K

603K

$102M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	408	37,911,100	73.7%	$6.4B
2025-Q4	397	37,651,591	73.2%	$6.9B
2025-Q3	355	37,447,876	72.8%	$4.5B
2025-Q2	348	37,862,386	73.6%	$4.0B
2025-Q1

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · AXSM

Large holders — 13G, passive (top 3 by % of class)

Holder	% of class	Type	As of
BlackRock, Inc.	5.3%	QII	2026-06-30	SEC →
RTW INVESTMENTS, LP	3.1%	QII	2025-06-30	SEC →
VANGUARD GROUP INC	0%	QII	2026-03-13	SEC →

Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).

Institutional ownership· 13F filers holding AXSM · 2026-Q1 methodology → sources →

408 holders

% of shares outstanding held

73.7%

Shares held (13F)

37,911,100

Reporting holders

408

Top holders

largest 100 of 408 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	3,912,8443.9M	$661M	7.60%	—
2	VANGUARD PORTFOLIO MANAGEMENT LLC	2,058,1702.1M	$348M	4.00%	NEW†
3	VANGUARD CAPITAL MANAGEMENT LLC	1,937,7521.9M	$328M	3.77%	NEW†
4	FMR LLC	1,566,9951.6M	$265M	3.05%	ADD 33%
5	PRICE T ROWE ASSOCIATES INC /MD/	1,317,0591.3M	$223M	2.56%	TRIM -13%
6	Invesco Ltd.	1,297,6781.3M	$219M	2.52%	—
7	GEODE CAPITAL MANAGEMENT, LLC	1,162,9811.2M	$197M	2.26%	ADD 15%
8	WELLINGTON MANAGEMENT GROUP LLP	1,145,3061.1M	$194M	2.23%	TRIM -6%
9	Deep Track Capital, LP	1,100,0001.1M	$186M	2.14%	TRIM -4%
10	STATE STREET CORP	986,809986,809	$167M	1.92%	ADD 3%
11	Assenagon Asset Management S.A.	865,958865,958	$146M	1.68%	ADD 85%
12	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	812,809812,809	$137M	1.58%	TRIM -18%
13	ADAGE CAPITAL PARTNERS GP, L.L.C.	737,578737,578	$125M	1.43%	ADD 101%
14	ALETHEA CAPITAL MANAGEMENT, LLC	649,114649,114	$110M	1.26%	TRIM -3%
15	D. E. Shaw & Co., Inc.	603,465603,465	$102M	1.17%	ADD 10%
16	BANK OF AMERICA CORP /DE/	598,091598,091	$101M	1.16%	TRIM -3%
17	FIRST TRUST ADVISORS LP	577,479577,479	$98M	1.12%	ADD 1230%
18	UBS Group AG	547,195547,195	$92M	1.06%	ADD 54%
19	EVENTIDE ASSET MANAGEMENT, LLC	519,558519,558	$88M	1.01%	TRIM -9%
20	MORGAN STANLEY	476,701476,701	$81M	0.93%	TRIM -3%
21	FRANKLIN RESOURCES INC	438,490438,490	$74M	0.85%	ADD 28%
22	Point72 Asset Management, L.P.	424,750424,750	$72M	0.83%	ADD 2260%
23	GOLDMAN SACHS GROUP INC	421,447421,447	$71M	0.82%	ADD 40%
24	Pictet Asset Management Holding SA	415,983415,983	$70M	0.81%	TRIM -5%
25	NORTHERN TRUST CORP	401,459401,459	$68M	0.78%	ADD 3%
26	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	395,118395,118	$67M	0.77%	—
27	Hood River Capital Management LLC	371,503371,503	$63M	0.72%	—
28	PRINCIPAL FINANCIAL GROUP INC	350,488350,488	$59M	0.68%	TRIM -3%
29	Nuveen, LLC	335,737335,737	$57M	0.65%	TRIM -4%
30	Qube Research & Technologies Ltd	335,334335,334	$57M	0.65%	ADD 3%
31	TWO SIGMA INVESTMENTS, LP	322,778322,778	$55M	0.63%	ADD 122%
32	VANGUARD FIDUCIARY TRUST CO	295,139295,139	$50M	0.57%	NEW
33	Driehaus Capital Management LLC	292,370292,370	$49M	0.57%	ADD 33%
34	CITADEL ADVISORS LLC	281,503281,503	$48M	0.55%	ADD 104%
35	PFM Health Sciences, LP	264,304264,304	$45M	0.51%	ADD 5%
36	LOOMIS SAYLES & CO L P	256,625256,625	$43M	0.50%	TRIM -19%
37	JPMORGAN CHASE & CO	270,160270,160	$43M	0.52%	ADD 16%
38	ORBIMED ADVISORS LLC	213,921213,921	$36M	0.42%	TRIM -15%
39	Sofinnova Investments, Inc.	212,747212,747	$36M	0.41%	ADD 1634%
40	Bank of New York Mellon Corp	206,644206,644	$35M	0.40%	TRIM -19%
41	FRONTIER CAPITAL MANAGEMENT CO LLC	203,066203,066	$34M	0.39%	ADD 29%
42	First Turn Management, LLC	188,772188,772	$32M	0.37%	TRIM -9%
43	BNP PARIBAS FINANCIAL MARKETS	188,146188,146	$32M	0.37%	TRIM -38%
44	CITIGROUP INC	185,658185,658	$31M	0.36%	TRIM -9%
45	VOYA INVESTMENT MANAGEMENT LLC	183,967183,967	$31M	0.36%	ADD 6%
46	AMERIPRISE FINANCIAL INC	176,314176,314	$30M	0.34%	ADD 76%
47	RENAISSANCE TECHNOLOGIES LLC	164,300164,300	$28M	0.32%	TRIM -3%
48	Woodline Partners LP	162,221162,221	$27M	0.32%	ADD 8%
49	MetLife Investment Management, LLC	152,645152,645	$26M	0.30%	TRIM -7%
50	PERCEPTIVE ADVISORS LLC	149,950149,950	$25M	0.29%	—
51	Aberdeen Group plc	149,688149,688	$25M	0.29%	ADD 54%
52	Voleon Capital Management LP	147,867147,867	$25M	0.29%	ADD 34%
53	RAYMOND JAMES FINANCIAL INC	147,766147,766	$24M	0.29%	—
54	1832 Asset Management L.P.	143,800143,800	$24M	0.28%	ADD 950%
55	Man Group plc	142,271142,271	$24M	0.28%	TRIM -38%
56	MARSHALL WACE, LLP	141,236141,236	$24M	0.27%	TRIM -56%
57	ALGERT GLOBAL LLC	135,460135,460	$23M	0.26%	TRIM -9%
58	Connor, Clark & Lunn Investment Management Ltd.	134,792134,792	$23M	0.26%	TRIM -28%
59	US BANCORP \DE\	131,414131,414	$22M	0.26%	—
60	MANUFACTURERS LIFE INSURANCE COMPANY, THE	117,093117,093	$20M	0.23%	TRIM -13%
61	Squarepoint Ops LLC	114,102114,102	$19M	0.22%	TRIM -26%
62	FEDERATED HERMES, INC.	108,571108,571	$18M	0.21%	ADD 24%
63	EMERALD ADVISERS, LLC	107,610107,610	$18M	0.21%	—
64	DEUTSCHE BANK AG\	104,266104,266	$18M	0.20%	ADD 6%
65	AQR CAPITAL MANAGEMENT LLC	104,059104,059	$18M	0.20%	—
66	WCM INVESTMENT MANAGEMENT, LLC	107,817107,817	$17M	0.21%	TRIM -4%
67	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	97,55097,550	$16M	0.19%	NEW
68	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	94,93794,937	$16M	0.18%	ADD 9%
69	ROYCE & ASSOCIATES LP	94,01794,017	$16M	0.18%	—
70	CANADA PENSION PLAN INVESTMENT BOARD	91,40091,400	$15M	0.18%	TRIM -11%
71	M&G PLC	91,33991,339	$15M	0.18%	—
72	DNB Asset Management AS	90,08890,088	$15M	0.18%	TRIM -11%
73	Cannell & Spears LLC	84,15484,154	$14M	0.16%	—
74	Nicholas Investment Partners, LP	81,47881,478	$14M	0.16%	TRIM -11%
75	Granite Investment Partners, LLC	80,29980,299	$14M	0.16%	TRIM -5%
76	Universal- Beteiligungs- und Servicegesellschaft mbH	70,72570,725	$12M	0.14%	ADD 3%
77	SEI INVESTMENTS CO	70,06470,064	$12M	0.14%	ADD 47%
78	Swiss National Bank	69,10069,100	$12M	0.13%	—
79	HSBC HOLDINGS PLC	68,45368,453	$12M	0.13%	NEW
80	ALLIANCEBERNSTEIN L.P.	62,82262,822	$11M	0.12%	ADD 18%
81	IRIDIAN ASSET MANAGEMENT LLC/CT	67,49167,491	$11M	0.13%	TRIM -9%
82	EMERALD MUTUAL FUND ADVISERS TRUST	67,05467,054	$11M	0.13%	—
83	Summit Financial, LLC	65,24965,249	$11M	0.13%	TRIM -8%
84	Rhenman & Partners Asset Management AB	63,80063,800	$11M	0.12%	TRIM -44%
85	Tri Locum Partners LP	62,11662,116	$10M	0.12%	TRIM -69%
86	WELLS FARGO & COMPANY/MN	61,40561,405	$10M	0.12%	TRIM -32%
87	IFP Advisors, Inc	60,99460,994	$10M	0.12%	TRIM -2%
88	NEUBERGER BERMAN GROUP LLC	60,75960,759	$10M	0.12%	TRIM -13%
89	Privium Fund Management B.V.	58,72958,729	$10M	0.11%	ADD 3%
90	Bridgewater Associates, LP	56,95156,951	$10M	0.11%	ADD 20%
91	HighTower Advisors, LLC	56,63356,633	$10M	0.11%	—
92	AXIOM INVESTORS LLC /DE	56,52956,529	$10M	0.11%	TRIM -11%
93	Hillsdale Investment Management Inc.	53,36353,363	$9M	0.10%	NEW
94	RHUMBLINE ADVISERS	51,61951,619	$9M	0.10%	—
95	California Public Employees Retirement System	50,87950,879	$9M	0.10%	NEW
96	HB Wealth Management, LLC	50,23750,237	$8M	0.10%	ADD 47%
97	NEW YORK STATE COMMON RETIREMENT FUND	50,11350,113	$8M	0.10%	ADD 18%
98	Cormorant Asset Management, LP	50,00050,000	$8M	0.10%	TRIM -33%
99	PEREGRINE CAPITAL MANAGEMENT LLC	47,29647,296	$8M	0.09%	—
100	SUSQUEHANNA INTERNATIONAL GROUP, LLP	47,19847,198	$8M	0.09%	ADD 58%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

3.5M

3.8M

3.9M

$661M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

2.1M

$348M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.9M

$328M

FMR LLC

1.0M

1.2M

977K

928K

1.2M

1.6M

$265M

PRICE T ROWE ASSOCIATES INC /MD/

31K

32K

613K

1.0M

1.5M

1.3M

$223M

Invesco Ltd.

692K

857K

572K

991K

1.3M

$219M

GEODE CAPITAL MANAGEMENT, LLC

913K

935K

989K

998K

1.0M

1.2M

$197M

WELLINGTON MANAGEMENT GROUP LLP

673K

703K

725K

1.3M

1.2M

1.1M

$194M

Deep Track Capital, LP

—

801K

900K

1.1M

$186M

STATE STREET CORP

947K

906K

959K

943K

958K

987K

$167M

Assenagon Asset Management S.A.

627K

181K

295K

468K

866K

$146M

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

—

989K

813K

$137M

ADAGE CAPITAL PARTNERS GP, L.L.C.

60K

48K

447K

445K

368K

738K

$125M

ALETHEA CAPITAL MANAGEMENT, LLC

734K

667K

671K

669K

649K

$110M

D. E. Shaw & Co., Inc.

20K

548K

201K

296K

549K

603K

$102M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	408	37,911,100	73.7%	$6.4B
2025-Q4	397	37,651,591	73.2%	$6.9B
2025-Q3	355	37,447,876	72.8%	$4.5B
2025-Q2	348	37,862,386	73.6%	$4.0B
2025-Q1

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · AXSM

Large holders — 13G, passive (top 3 by % of class)

Holder	% of class	Type	As of
BlackRock, Inc.	5.3%	QII	2026-06-30	SEC →
RTW INVESTMENTS, LP	3.1%	QII	2025-06-30	SEC →
VANGUARD GROUP INC	0%	QII	2026-03-13	SEC →

AXSM US Equity☆

Institutional ownership· 13F filers holding AXSM · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · AXSM

Institutional ownership· 13F filers holding AXSM · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · AXSM

AXSM US Equity