| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | Alpha Wave Global, LP | 3,707,7573.7M | $83M | 10.57% | — |
| 2 | Commodore Capital LP | 2,723,1962.7M | $61M | 7.76% | ADD 49% |
| 3 | Vestal Point Capital, LP | 2,064,0752.1M | $46M | 5.88% | TRIM -17% |
| 4 | PERCEPTIVE ADVISORS LLC | 2,009,8932.0M | $45M | 5.73% | ADD 13% |
| 5 | Spruce Street Capital LP | 1,325,2101.3M | $29M | 3.78% | ADD 495% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 1,207,0251.2M | $27M | 3.44% | NEW† |
| 7 | FRANKLIN RESOURCES INC | 1,101,8741.1M | $25M | 3.14% | — |
| 8 | Vivo Capital, LLC | 1,035,5511.0M | $23M | 2.95% | — |
| 9 | ARMISTICE CAPITAL, LLC | 912,000912,000 | $21M | 2.60% | TRIM -41% |
| 10 | MILLENNIUM MANAGEMENT LLC | 821,982821,982 | $18M | 2.34% | ADD 30% |
| 11 | 72 Investment Holdings, LLC | 667,778667,778 | $15M | 1.90% | — |
| 12 | BlackRock, Inc. | 666,188666,188 | $15M | 1.90% | ADD 10% |
| 13 | Ikarian Capital, LLC | 515,000515,000 | $12M | 1.47% | — |
| 14 | Point72 Asset Management, L.P. | 503,087503,087 | $11M | 1.43% | TRIM -69% |
| 15 | Venrock Adviser, LLC | 500,000500,000 | $11M | 1.42% | NEW |
| 16 | Affinity Asset Advisors, LLC | 500,000500,000 | $11M | 1.42% | NEW |
| 17 | Integral Health Asset Management, LLC | 500,000500,000 | $11M | 1.42% | ADD 33% |
| 18 | Driehaus Capital Management LLC | 486,726486,726 | $11M | 1.39% | ADD 45% |
| 19 | NORTHERN TRUST CORP | 473,403473,403 | $11M | 1.35% | — |
| 20 | JENNISON ASSOCIATES LLC | 386,426386,426 | $9M | 1.10% | NEW |
| 21 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 385,000385,000 | $9M | 1.10% | NEW |
| 22 | PRICE T ROWE ASSOCIATES INC /MD/ | 371,208371,208 | $8M | 1.06% | ADD 1128% |
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 292,899292,899 | $7M | 0.83% | — |
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 238,498238,498 | $5M | 0.68% | ADD 102% |
| 25 | ALKEON CAPITAL MANAGEMENT LLC | 227,101227,101 | $5M | 0.65% | TRIM -52% |
| 26 | TWO SIGMA INVESTMENTS, LP | 216,099216,099 | $5M | 0.62% | ADD 54% |
| 27 | Qube Research & Technologies Ltd | 209,268209,268 | $5M | 0.60% | ADD 86% |
| 28 | STATE STREET CORP | 199,503199,503 | $4M | 0.57% | ADD 53% |
| 29 | MARSHALL WACE, LLP | 176,347176,347 | $4M | 0.50% | TRIM -9% |
| 30 | AWM Investment Company, Inc. | 170,000170,000 | $4M | 0.48% | TRIM -24% |
| 31 | ORBIMED ADVISORS LLC | 167,500167,500 | $4M | 0.48% | ADD 34% |
| 32 | VANGUARD FIDUCIARY TRUST CO | 165,272165,272 | $4M | 0.47% | NEW |
| 33 | BOOTHBAY FUND MANAGEMENT, LLC | 139,304139,304 | $3M | 0.40% | — |
| 34 | Eversept Partners, LP | 125,168125,168 | $3M | 0.36% | NEW |
| 35 | GOLDMAN SACHS GROUP INC | 104,717104,717 | $2M | 0.30% | TRIM -33% |
| 36 | RENAISSANCE TECHNOLOGIES LLC | 103,499103,499 | $2M | 0.29% | ADD 6% |
| 37 | Saturn V Capital Management LP | 88,99988,999 | $2M | 0.25% | NEW |
| 38 | STIFEL FINANCIAL CORP | 86,33586,335 | $2M | 0.25% | — |
| 39 | Almitas Capital LLC | 78,52078,520 | $2M | 0.22% | — |
| 40 | MORGAN STANLEY | 68,65468,654 | $2M | 0.20% | ADD 5% |
| 41 | ACADIAN ASSET MANAGEMENT LLC | 60,07660,076 | $1M | 0.17% | ADD 4% |
| 42 | WELLINGTON MANAGEMENT GROUP LLP | 59,79959,799 | $1M | 0.17% | TRIM -13% |
| 43 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 52,65352,653 | $1M | 0.15% | TRIM -32% |
| 44 | D. E. Shaw & Co., Inc. | 45,34345,343 | $1M | 0.13% | TRIM -64% |
| 45 | TD Asset Management Inc | 43,80043,800 | $984,624 | 0.12% | NEW |
| 46 | Hudson Bay Capital Management LP | 43,76243,762 | $983,770 | 0.12% | ADD 26% |
| 47 | AdvisorShares Investments LLC | 41,02341,023 | $922,197 | 0.12% | TRIM -7% |
| 48 | 683 Capital Management, LLC | 40,00040,000 | $899,200 | 0.11% | TRIM -38% |
| 49 | XTX Topco Ltd | 39,84139,841 | $895,626 | 0.11% | ADD 91% |
| 50 | DIMENSIONAL FUND ADVISORS LP | 39,32439,324 | $884,004 | 0.11% | ADD 26% |
| 51 | Brevan Howard Capital Management LP | 38,78238,782 | $871,819 | 0.11% | NEW |
| 52 | Quantinno Capital Management LP | 36,06936,069 | $810,831 | 0.10% | — |
| 53 | Balyasny Asset Management L.P. | 32,11132,111 | $721,855 | 0.09% | ADD 189% |
| 54 | JANE STREET GROUP, LLC | 30,05830,058 | $675,704 | 0.09% | TRIM -85% |
| 55 | Squarepoint Ops LLC | 29,96129,961 | $673,523 | 0.09% | NEW |
| 56 | Allianz Asset Management GmbH | 28,50028,500 | $640,680 | 0.08% | TRIM -34% |
| 57 | BANK OF AMERICA CORP /DE/ | 25,67725,677 | $577,219 | 0.07% | ADD 131% |
| 58 | ALPS ADVISORS INC | 25,28825,288 | $568,474 | 0.07% | — |
| 59 | BARCLAYS PLC | 25,03625,036 | $562,809 | 0.07% | TRIM -18% |
| 60 | BROWN ADVISORY INC | 25,00025,000 | $562,000 | 0.07% | — |
| 61 | Y-Intercept (Hong Kong) Ltd | 23,94523,945 | $538,284 | 0.07% | NEW |
| 62 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 23,74723,747 | $533,833 | 0.07% | NEW |
| 63 | IEQ CAPITAL, LLC | 23,72723,727 | $533,383 | 0.07% | TRIM -68% |
| 64 | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 22,17522,175 | $498,494 | 0.06% | — |
| 65 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 18,08318,083 | $406,505 | 0.05% | NEW |
| 66 | UBS Group AG | 17,25017,250 | $387,780 | 0.05% | TRIM -7% |
| 67 | Revisor Wealth Management LLC | 17,13017,130 | $385,082 | 0.05% | NEW |
| 68 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 17,01817,018 | $382,565 | 0.05% | — |
| 69 | SCS Capital Management LLC | 16,84016,840 | $378,563 | 0.05% | TRIM -50% |
| 70 | POLEN CAPITAL MANAGEMENT LLCtracked | 16,61316,613 | $373,460 | 0.05% | NEW |
| 71 | Vanguard Personalized Indexing Management, LLC | 15,64615,646 | $351,722 | 0.04% | TRIM -5% |
| 72 | AMERICAN CENTURY COMPANIES INC | 14,18614,186 | $318,901 | 0.04% | ADD 37% |
| 73 | TORONTO DOMINION BANK | 13,43413,434 | $301,996 | 0.04% | NEW |
| 74 | AMERIPRISE FINANCIAL INC | 13,32413,324 | $299,524 | 0.04% | — |
| 75 | Clearstead Advisors, LLC | 13,31213,312 | $299,254 | 0.04% | NEW |
| 76 | Catalyst Funds Management Pty Ltd | 11,40011,400 | $256,272 | 0.03% | NEW |
| 77 | BANK OF MONTREAL /CAN/ | 11,34311,343 | $254,991 | 0.03% | — |
| 78 | Vanguard Global Advisers, LLC | 10,64910,649 | $239,390 | 0.03% | NEW |
| 79 | Diametric Capital, LP | 10,31510,315 | $231,881 | 0.03% | NEW |
| 80 | OMERS ADMINISTRATION Corp | 9,7009,700 | $218,056 | 0.03% | TRIM -22% |
| 81 | CITIGROUP INC | 9,4309,430 | $211,986 | 0.03% | TRIM -25% |
| 82 | FMR LLC | 6,3146,314 | $141,934 | 0.02% | — |
| 83 | WHITTIER TRUST CO OF NEVADA INC | 2,4822,482 | $55,919 | 0.01% | — |
| 84 | ROTHSCHILD INVESTMENT LLC | 1,6851,685 | $37,879 | 0.00% | TRIM -42% |
| 85 | PNC FINANCIAL SERVICES GROUP, INC. | 1,2061,206 | $27,111 | 0.00% | TRIM -8% |
| 86 | Advisory Services Network, LLC | 802802 | $18,029 | 0.00% | NEW |
| 87 | WELLS FARGO & COMPANY/MN | 790790 | $17,759 | 0.00% | ADD 3% |
| 88 | FEDERATED HERMES, INC. | 654654 | $14,702 | 0.00% | TRIM -15% |
| 89 | EverSource Wealth Advisors, LLC | 628628 | $14,117 | 0.00% | TRIM -5% |
| 90 | Torren Management, LLC | 558558 | $12,544 | 0.00% | TRIM -84% |
| 91 | JONES FINANCIAL COMPANIES LLLP | 533533 | $10,927 | 0.00% | ADD 1515% |
| 92 | SIMPLEX TRADING, LLC | 450450 | $10,116 | 0.00% | NEW |
| 93 | GROUP ONE TRADING LLC | 400400 | $8,992 | 0.00% | TRIM -72% |
| 94 | NISA INVESTMENT ADVISORS, LLC | 338338 | $7,598 | 0.00% | — |
| 95 | BNP PARIBAS FINANCIAL MARKETS | 314314 | $7,059 | 0.00% | TRIM -99% |
| 96 | Russell Investments Group, Ltd. | 306306 | $6,879 | 0.00% | — |
| 97 | Accent Capital Management, LLC | 275275 | $6,182 | 0.00% | NEW |
| 98 | US BANCORP \DE\ | 110110 | $2,473 | 0.00% | TRIM -3% |
| 99 | CWM, LLC | 102102 | $2,293 | 0.00% | TRIM -34% |
| 100 | Cornerstone Financial Management LLC | 6969 | $1,551 | 0.00% | — |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| Alpha Wave Global, LP | 3.7M | 3.7M | 3.7M | 3.7M | 3.7M | 3.7M | $83M |
| Commodore Capital LP | — | — | — | — | 1.8M | 2.7M | $61M |
| Vestal Point Capital, LP | 915K | 915K | 950K | 950K | 2.5M | 2.1M | $46M |
| PERCEPTIVE ADVISORS LLC | — | — | — | 155K | 1.8M | 2.0M | $45M |
| Spruce Street Capital LP | — | — | — | — | 223K | 1.3M | $29M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 1.2M | $27M |
| FRANKLIN RESOURCES INC | 1.2M | 1.2M | 1.2M | 1.2M | 1.1M | 1.1M | $25M |
| Vivo Capital, LLC | — | — | — | — | 1.0M | 1.0M | $23M |
| ARMISTICE CAPITAL, LLC | 650K | 1.6M | 1.6M | 1.6M | 1.5M | 912K | $21M |
| MILLENNIUM MANAGEMENT LLC | — | 16K | 303K | 316K | 630K | 822K | $18M |
| 72 Investment Holdings, LLC | 668K | 668K | 668K | 668K | 668K | 668K | $15M |
| BlackRock, Inc. | 1.5M | 1.5M | 562K | 368K | 608K | 666K | $15M |
| Ikarian Capital, LLC | 350K | 175K | 110K | 110K | 515K | 515K | $12M |
| Point72 Asset Management, L.P. | 1.7M | 1.2M | 1.3M | 1.3M | 1.6M | 503K | $11M |
| Venrock Adviser, LLC | — | — | — | — | — | 500K | $11M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).
| Quarter | Holders | Shares held | % shares out | Value held |
|---|---|---|---|---|
| 2026-Q1 | 110 | 26,830,701 | 76.5% | $602M |
| 2025-Q4 | 97 | 24,487,036 | 69.8% | $436M |
| 2025-Q3 | 77 | 16,952,921 | 48.3% | $68M |
| 2025-Q2 | 80 | 17,308,497 | 49.3% | $38M |
| 2025-Q1 | 83 | 20,845,493 | 59.4% | $45M |
| 2024-Q4 | 77 | 22,530,140 | 64.2% | $95M |
| 2024-Q3 | 75 | 22,963,889 | 65.4% | $266M |
| 2024-Q2 | 58 | 18,604,453 | 53.0% | $199M |
| 2024-Q1 | 53 | 16,046,027 | 45.7% | $246M |
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).
