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ISRG vs ZBH

Intuitive Surgical Inc (ISRG) and Zimmer Biomet Holdings, Inc. (ZBH) are both filed with the SEC under Orthopedic, Prosthetic & Surgical Appliances & Supplies. ISRG is 6.8× ZBH's size by market cap ($129.7B against $19.0B); ISRG trades at the higher fiscal-year P/E (46.6× against 28.0×); ISRG reports the higher net margin (26.1% against 8.6%); ISRG grew sales faster over three years (+18.4% against +5.9%); and over the past year ZBH returned -2.9% against ISRG's -21.4%.

ISRGZBH
Last close$372.60$100.91
Market cap$129.7B$19.0B
P/E (FY)46.6×28.0×
P/S11.9×2.3×
EV/EBITDA11.8×
Gross margin60.7%
Operating margin26.9%13.3%
Net margin26.1%8.6%
Return on equity16.7%5.6%
Sales growth (3y)+18.4%+5.9%
EPS growth (3y)+29.2%+47.8%
Dividend yield1.0%
1-year return-21.4%-2.9%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year — FY2025 (ended 2025-12-31) for both. — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

ISRGZBH
Institutional holders (13F)2,290908
Insider buyers − sellers (180d)-5-2
Congressional trades disclosed (180d)11
Executive-branch officials on file — trades disclosed (180d)166

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5.

ISRG vs ZBH: common questions

Is ISRG bigger than ZBH?
ISRG carries the larger market cap — $129.7B against $19.0B, both struck on 2026-08-27.
Which trades at a higher P/E, ISRG or ZBH?
ISRG, at a fiscal-year 46.6× against 28.0× for ZBH. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have ISRG and ZBH performed over the past year?
ZBH returned -2.9% and ISRG -21.4%, measured on the trailing calendar year to the last close.
How many institutions hold ISRG and ZBH?
2,290 13F filers report a position in ISRG and 908 in ZBH, on the latest quarter in the panel.
Are ISRG and ZBH in the same industry?
Both are filed with the SEC under Orthopedic, Prosthetic & Surgical Appliances & Supplies, which is the classification this pairing is built on.

ISRG overview · ZBH overview · ISRG institutional ownership · ZBH institutional ownership · Congress and ISRG · Congress and ZBH · Executive branch and ISRG · Executive branch and ZBH

More in Orthopedic, Prosthetic & Surgical Appliances & Supplies: ALGN vs EW · ALGN vs ISRG · ALGN vs STE · ALGN vs ZBH

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/isrg-vs-zbh