ISRG vs STE
Intuitive Surgical Inc (ISRG) and STERIS plc (STE) are both filed with the SEC under Orthopedic, Prosthetic & Surgical Appliances & Supplies. ISRG is 5.7× STE's size by market cap ($129.7B against $22.7B); ISRG trades at the higher fiscal-year P/E (46.6× against 29.4×); ISRG reports the higher net margin (26.1% against 13.2%); ISRG grew sales faster over three years (+18.4% against +9.4%); and over the past year STE returned -3.5% against ISRG's -21.4%.
| ISRG | STE | |
|---|---|---|
| Last close | $372.60 | $233.78 |
| Market cap | $129.7B | $22.7B |
| P/E (FY) | 46.6× | 29.4× |
| P/S | 11.9× | 3.8× |
| Gross margin | 60.7% | 44.2% |
| Operating margin | 26.9% | 18.6% |
| Net margin | 26.1% | 13.2% |
| Return on equity | 16.7% | 11.3% |
| Sales growth (3y) | +18.4% | +9.4% |
| EPS growth (3y) | +29.2% | +95.0% |
| Dividend yield | — | 1.1% |
| 1-year return | -21.4% | -3.5% |
Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year, and the two differ: ISRG FY2025 (ended 2025-12-31); STE FY2026 (ended 2026-03-31). — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.
Who holds them, and who has traded them
| ISRG | STE | |
|---|---|---|
| Institutional holders (13F) | 2,290 | 836 |
| Insider buyers − sellers (180d) | -5 | -4 |
| Congressional trades disclosed (180d) | 1 | 10 |
| Executive-branch officials on file — trades disclosed (180d) | 16 | 3 |
Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5.
ISRG vs STE: common questions
- Is ISRG bigger than STE?
- ISRG carries the larger market cap — $129.7B against $22.7B, both struck on 2026-08-27.
- Which trades at a higher P/E, ISRG or STE?
- ISRG, at a fiscal-year 46.6× against 29.4× for STE. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
- How have ISRG and STE performed over the past year?
- STE returned -3.5% and ISRG -21.4%, measured on the trailing calendar year to the last close.
- How many institutions hold ISRG and STE?
- 2,290 13F filers report a position in ISRG and 836 in STE, on the latest quarter in the panel.
- Are ISRG and STE in the same industry?
- Both are filed with the SEC under Orthopedic, Prosthetic & Surgical Appliances & Supplies, which is the classification this pairing is built on.
ISRG overview → · STE overview → · ISRG institutional ownership → · STE institutional ownership → · Congress and ISRG → · Congress and STE → · Executive branch and ISRG → · Executive branch and STE →
More in Orthopedic, Prosthetic & Surgical Appliances & Supplies: ALGN vs EW · ALGN vs ISRG · ALGN vs STE · ALGN vs ZBH
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Source: SPZCO — https://spzco.com/vs/isrg-vs-ste