TRDA US Equity

Entrada Therapeutics, Inc.

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Health Care · Pharmaceutical Preparations · CIK 1689375 · FYE 1231

$6.55

+0.72 (+12.35%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding TRDA · 2026-Q1 methodology → sources →

119 holders

% of shares outstanding held

65.6%

Shares held (13F)

25,477,280

Reporting holders

119

Top holders

largest 100 of 119 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BAKER BROS. ADVISORS LP	5,072,7305.1M	$64M	13.07%	—
2	5AM Venture Management, LLC	4,056,3794.1M	$51M	10.45%	—
3	BlackRock, Inc.	2,358,7932.4M	$30M	6.08%	ADD 10%
4	TCG Crossover Management, LLC	2,287,5002.3M	$29M	5.89%	ADD 10%
5	VANGUARD CAPITAL MANAGEMENT LLC	1,256,0131.3M	$16M	3.24%	NEW†
6	WELLINGTON MANAGEMENT GROUP LLP	1,034,7821.0M	$13M	2.67%	—
7	StepStone Group LP	761,277761,277	$10M	1.96%	—
8	GEODE CAPITAL MANAGEMENT, LLC	667,347667,347	$8M	1.72%	ADD 4%
9	STATE STREET CORP	533,798533,798	$7M	1.38%	ADD 5%
10	PRICE T ROWE ASSOCIATES INC /MD/	526,043526,043	$7M	1.36%	ADD 61%
11	MILLENNIUM MANAGEMENT LLC	519,356519,356	$7M	1.34%	ADD 4%
12	Jones Hill Capital LP	374,010374,010	$5M	0.96%	NEW
13	JACOBS LEVY EQUITY MANAGEMENT, INC	333,914333,914	$4M	0.86%	TRIM -8%
14	ACADIAN ASSET MANAGEMENT LLC	333,169333,169	$4M	0.86%	ADD 7%
15	DIMENSIONAL FUND ADVISORS LP	324,471324,471	$4M	0.84%	ADD 19%
16	NORTHERN TRUST CORP	234,992234,992	$3M	0.61%	ADD 4%
17	VANGUARD PORTFOLIO MANAGEMENT LLC	220,494220,494	$3M	0.57%	NEW
18	Woodline Partners LP	215,977215,977	$3M	0.56%	ADD 52%
19	CITADEL ADVISORS LLC	215,018215,018	$3M	0.55%	TRIM -27%
20	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	214,751214,751	$3M	0.55%	TRIM -3%
21	GOLDMAN SACHS GROUP INC	212,780212,780	$3M	0.55%	ADD 4%
22	Lynx1 Capital Management LP	211,689211,689	$3M	0.55%	ADD 310%
23	Longaeva Partners L.P.	204,978204,978	$3M	0.53%	NEW
24	RENAISSANCE TECHNOLOGIES LLC	202,084202,084	$3M	0.52%	TRIM -20%
25	BNP PARIBAS FINANCIAL MARKETS	181,148181,148	$2M	0.47%	—
26	MORGAN STANLEY	176,126176,126	$2M	0.45%	TRIM -32%
27	Nuveen, LLC	175,648175,648	$2M	0.45%	ADD 211%
28	Nantahala Capital Management, LLC	159,332159,332	$2M	0.41%	NEW
29	VANGUARD FIDUCIARY TRUST CO	156,861156,861	$2M	0.40%	NEW
30	XTX Topco Ltd	129,562129,562	$2M	0.33%	ADD 10%
31	ROYCE & ASSOCIATES LP	120,845120,845	$2M	0.31%	TRIM -51%
32	MOORE CAPITAL MANAGEMENT, LP	105,000105,000	$1M	0.27%	—
33	ACUTA CAPITAL PARTNERS, LLC	89,35889,358	$1M	0.23%	NEW
34	Qube Research & Technologies Ltd	87,45387,453	$1M	0.23%	TRIM -50%
35	Trexquant Investment LP	82,73382,733	$1M	0.21%	TRIM -32%
36	AQR CAPITAL MANAGEMENT LLC	79,49379,493	$1M	0.20%	ADD 203%
37	D. E. Shaw & Co., Inc.	79,04779,047	$997,573	0.20%	ADD 18%
38	AMERICAN CENTURY COMPANIES INC	77,97177,971	$983,994	0.20%	ADD 4%
39	Bank of New York Mellon Corp	76,42776,427	$964,509	0.20%	TRIM -4%
40	Quantinno Capital Management LP	71,01871,018	$896,247	0.18%	ADD 5%
41	MANUFACTURERS LIFE INSURANCE COMPANY, THE	70,65670,656	$891,679	0.18%	ADD 25%
42	AMERIPRISE FINANCIAL INC	70,28070,280	$886,934	0.18%	TRIM -17%
43	MARSHALL WACE, LLP	53,76453,764	$678,501	0.14%	ADD 160%
44	TD Asset Management Inc	53,58853,588	$676,281	0.14%	ADD 42%
45	Nan Fung Group Holdings Ltd	49,08249,082	$619,415	0.13%	—
46	CANTOR FITZGERALD, L. P.	47,00047,000	$593,140	0.12%	TRIM -18%
47	TWO SIGMA INVESTMENTS, LP	44,60244,602	$562,877	0.11%	TRIM -10%
48	Invesco Ltd.	41,92641,926	$529,106	0.11%	ADD 2%
49	MARTINGALE ASSET MANAGEMENT L P	41,76341,763	$527,050	0.11%	ADD 13%
50	GREAT LAKES ADVISORS, LLC	41,53141,531	$524,121	0.11%	TRIM -4%
51	BANK OF AMERICA CORP /DE/	39,21239,212	$494,855	0.10%	TRIM -41%
52	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	37,50237,502	$473,275	0.10%	—
53	HSBC HOLDINGS PLC	38,13738,137	$471,755	0.10%	TRIM -8%
54	JANE STREET GROUP, LLC	37,21337,213	$469,628	0.10%	TRIM -57%
55	RHUMBLINE ADVISERS	35,93835,938	$453,528	0.09%	—
56	UBS Group AG	31,98131,981	$403,600	0.08%	ADD 68%
57	ADAR1 Capital Management, LLC	30,50030,500	$384,910	0.08%	NEW
58	BARCLAYS PLC	28,67628,676	$361,892	0.07%	TRIM -57%
59	Brevan Howard Capital Management LP	26,34926,349	$332,524	0.07%	TRIM -45%
60	BRIDGEWAY CAPITAL MANAGEMENT, LLC	25,00025,000	$315,500	0.06%	TRIM -38%
61	DEUTSCHE BANK AG\	24,67924,679	$311,449	0.06%	ADD 19%
62	Creative Planning	22,23022,230	$280,543	0.06%	—
63	Shay Capital LLC	21,54821,548	$271,936	0.06%	NEW
64	SUSQUEHANNA INTERNATIONAL GROUP, LLP	20,31520,315	$256,375	0.05%	ADD 32%
65	ALLIANCEBERNSTEIN L.P.	24,32024,320	$250,010	0.06%	—
66	Allspring Global Investments Holdings, LLC	19,46519,465	$245,648	0.05%	ADD 11%
67	Vanguard Global Advisers, LLC	18,39818,398	$232,183	0.05%	NEW
68	HARBOR CAPITAL ADVISORS, INC.	18,17518,175	$229,000	0.05%	NEW
69	MetLife Investment Management, LLC	17,80217,802	$224,661	0.05%	—
70	CANADA PENSION PLAN INVESTMENT BOARD	17,70017,700	$223,374	0.05%	TRIM -31%
71	Quadrature Capital Ltd	17,53817,538	$221,330	0.05%	TRIM -14%
72	FMR LLC	16,94316,943	$213,820	0.04%	—
73	Dynamic Technology Lab Private Ltd	16,47416,474	$207,902	0.04%	TRIM -35%
74	JPMORGAN CHASE & CO	14,84714,847	$174,749	0.04%	TRIM -79%
75	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	13,57713,577	$171,342	0.03%	ADD 2%
76	ExodusPoint Capital Management, LP	12,06712,067	$152,286	0.03%	TRIM -68%
77	Inscription Capital, LLC	11,83511,835	$149,358	0.03%	—
78	Russell Investments Group, Ltd.	11,63311,633	$146,806	0.03%	—
79	FRANKLIN RESOURCES INC	11,10211,102	$140,107	0.03%	NEW
80	IHT Wealth Management, LLC	11,10011,100	$140,082	0.03%	—
81	WELLS FARGO & COMPANY/MN	11,01111,011	$138,959	0.03%	TRIM -66%
82	Police & Firemen's Retirement System of New Jersey	9,4719,471	$119,524	0.02%	—
83	NEW YORK STATE COMMON RETIREMENT FUND	8,8778,877	$112,028	0.02%	—
84	China Universal Asset Management Co., Ltd.	6,7946,794	$85,740	0.02%	ADD 9%
85	CWM, LLC	6,7886,788	$85,665	0.02%	ADD 221%
86	CITIGROUP INC	4,8534,853	$61,245	0.01%	ADD 18%
87	Versant Capital Management, Inc	4,0464,046	$51,061	0.01%	—
88	Legal & General Group Plc	2,5572,557	$32,269	0.01%	—
89	Ameritas Investment Partners, Inc.	2,4172,417	$30,503	0.01%	—
90	Mirae Asset Global Investments Co., Ltd.	1,9971,997	$25,202	0.01%	ADD 8%
91	Tower Research Capital LLC (TRC)	1,6701,670	$21,075	0.00%	TRIM -14%
92	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	1,5401,540	$19,435	0.00%	TRIM -12%
93	Zurcher Kantonalbank (Zurich Cantonalbank)	1,4171,417	$17,883	0.00%	ADD 228%
94	PNC FINANCIAL SERVICES GROUP, INC.	1,1411,141	$14,400	0.00%	—
95	Sterling Capital Management LLC	943943	$11,901	0.00%	TRIM -43%
96	Arax Advisory Partners	919919	$11,598	0.00%	—
97	GF FUND MANAGEMENT CO. LTD.	852852	$10,752	0.00%	ADD 13%
98	GAMMA Investing LLC	480480	$6,058	0.00%	ADD 405%
99	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	435435	$5,490	0.00%	ADD 1877%
100	EverSource Wealth Advisors, LLC	420420	$5,301	0.00%	ADD 12%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BAKER BROS. ADVISORS LP

4.9M

5.1M

$64M

5AM Venture Management, LLC

4.4M

4.3M

4.1M

$51M

BlackRock, Inc.

2.0M

2.1M

2.4M

$30M

TCG Crossover Management, LLC

585K

2.1M

2.3M

$29M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.3M

$16M

WELLINGTON MANAGEMENT GROUP LLP

1.0M

1.1M

954K

1.0M

$13M

StepStone Group LP

761K

$10M

GEODE CAPITAL MANAGEMENT, LLC

574K

589K

632K

645K

640K

667K

$8M

STATE STREET CORP

505K

494K

496K

499K

509K

534K

$7M

PRICE T ROWE ASSOCIATES INC /MD/

2.9M

2.7M

2.6M

361K

327K

526K

$7M

MILLENNIUM MANAGEMENT LLC

13K

—

170K

837K

498K

519K

$7M

Jones Hill Capital LP

—

374K

$5M

JACOBS LEVY EQUITY MANAGEMENT, INC

213K

211K

221K

316K

363K

334K

$4M

ACADIAN ASSET MANAGEMENT LLC

51K

21K

46K

298K

311K

333K

$4M

DIMENSIONAL FUND ADVISORS LP

217K

327K

424K

394K

273K

324K

$4M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	119	25,477,280	65.6%	$321M
2025-Q4	113	24,448,949	63.0%	$251M
2025-Q3	116	28,609,874	73.7%	$169M
2025-Q2	107	29,603,196	76.3%	$199M
2025-Q1	110	30,241,830	77.9%	$275M
2024-Q4	102	30,666,008	79.0%	$530M
2024-Q3	97	30,110,808	77.6%	$481M
2024-Q2	83	29,678,772	76.5%	$423M
2024-Q1	77	26,250,982	67.6%	$372M
2023-Q4	62	26,345,408	67.9%	$398M
2023-Q3	55	26,035,608	67.1%	$411M

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · TRDA

Activists — 13D, active intent

5AM Ventures V, L.P.10.8%NEWSCHEDULE 13D/A · Amd 1 · event 2025-11-14SEC →

4,123,849 shares · 7 reporting persons

Large holders — 13G, passive (top 5 by % of class)

Holder

% of class

Type

As of

ROCHE FINANCE LTD

6.9%

Exempt

2024-12-31

SEC →

BlackRock, Inc.

5.3%

QII

2024-12-31

SEC →

TCG Crossover GP I, LLC

Passive

2025-11-19

SEC →

JANUS HENDERSON GROUP PLC

Institutional ownership· 13F filers holding TRDA · 2026-Q1 methodology → sources →

119 holders

% of shares outstanding held

65.6%

Shares held (13F)

25,477,280

Reporting holders

119

Top holders

largest 100 of 119 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BAKER BROS. ADVISORS LP	5,072,7305.1M	$64M	13.07%	—
2	5AM Venture Management, LLC	4,056,3794.1M	$51M	10.45%	—
3	BlackRock, Inc.	2,358,7932.4M	$30M	6.08%	ADD 10%
4	TCG Crossover Management, LLC	2,287,5002.3M	$29M	5.89%	ADD 10%
5	VANGUARD CAPITAL MANAGEMENT LLC	1,256,0131.3M	$16M	3.24%	NEW†
6	WELLINGTON MANAGEMENT GROUP LLP	1,034,7821.0M	$13M	2.67%	—
7	StepStone Group LP	761,277761,277	$10M	1.96%	—
8	GEODE CAPITAL MANAGEMENT, LLC	667,347667,347	$8M	1.72%	ADD 4%
9	STATE STREET CORP	533,798533,798	$7M	1.38%	ADD 5%
10	PRICE T ROWE ASSOCIATES INC /MD/	526,043526,043	$7M	1.36%	ADD 61%
11	MILLENNIUM MANAGEMENT LLC	519,356519,356	$7M	1.34%	ADD 4%
12	Jones Hill Capital LP	374,010374,010	$5M	0.96%	NEW
13	JACOBS LEVY EQUITY MANAGEMENT, INC	333,914333,914	$4M	0.86%	TRIM -8%
14	ACADIAN ASSET MANAGEMENT LLC	333,169333,169	$4M	0.86%	ADD 7%
15	DIMENSIONAL FUND ADVISORS LP	324,471324,471	$4M	0.84%	ADD 19%
16	NORTHERN TRUST CORP	234,992234,992	$3M	0.61%	ADD 4%
17	VANGUARD PORTFOLIO MANAGEMENT LLC	220,494220,494	$3M	0.57%	NEW
18	Woodline Partners LP	215,977215,977	$3M	0.56%	ADD 52%
19	CITADEL ADVISORS LLC	215,018215,018	$3M	0.55%	TRIM -27%
20	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	214,751214,751	$3M	0.55%	TRIM -3%
21	GOLDMAN SACHS GROUP INC	212,780212,780	$3M	0.55%	ADD 4%
22	Lynx1 Capital Management LP	211,689211,689	$3M	0.55%	ADD 310%
23	Longaeva Partners L.P.	204,978204,978	$3M	0.53%	NEW
24	RENAISSANCE TECHNOLOGIES LLC	202,084202,084	$3M	0.52%	TRIM -20%
25	BNP PARIBAS FINANCIAL MARKETS	181,148181,148	$2M	0.47%	—
26	MORGAN STANLEY	176,126176,126	$2M	0.45%	TRIM -32%
27	Nuveen, LLC	175,648175,648	$2M	0.45%	ADD 211%
28	Nantahala Capital Management, LLC	159,332159,332	$2M	0.41%	NEW
29	VANGUARD FIDUCIARY TRUST CO	156,861156,861	$2M	0.40%	NEW
30	XTX Topco Ltd	129,562129,562	$2M	0.33%	ADD 10%
31	ROYCE & ASSOCIATES LP	120,845120,845	$2M	0.31%	TRIM -51%
32	MOORE CAPITAL MANAGEMENT, LP	105,000105,000	$1M	0.27%	—
33	ACUTA CAPITAL PARTNERS, LLC	89,35889,358	$1M	0.23%	NEW
34	Qube Research & Technologies Ltd	87,45387,453	$1M	0.23%	TRIM -50%
35	Trexquant Investment LP	82,73382,733	$1M	0.21%	TRIM -32%
36	AQR CAPITAL MANAGEMENT LLC	79,49379,493	$1M	0.20%	ADD 203%
37	D. E. Shaw & Co., Inc.	79,04779,047	$997,573	0.20%	ADD 18%
38	AMERICAN CENTURY COMPANIES INC	77,97177,971	$983,994	0.20%	ADD 4%
39	Bank of New York Mellon Corp	76,42776,427	$964,509	0.20%	TRIM -4%
40	Quantinno Capital Management LP	71,01871,018	$896,247	0.18%	ADD 5%
41	MANUFACTURERS LIFE INSURANCE COMPANY, THE	70,65670,656	$891,679	0.18%	ADD 25%
42	AMERIPRISE FINANCIAL INC	70,28070,280	$886,934	0.18%	TRIM -17%
43	MARSHALL WACE, LLP	53,76453,764	$678,501	0.14%	ADD 160%
44	TD Asset Management Inc	53,58853,588	$676,281	0.14%	ADD 42%
45	Nan Fung Group Holdings Ltd	49,08249,082	$619,415	0.13%	—
46	CANTOR FITZGERALD, L. P.	47,00047,000	$593,140	0.12%	TRIM -18%
47	TWO SIGMA INVESTMENTS, LP	44,60244,602	$562,877	0.11%	TRIM -10%
48	Invesco Ltd.	41,92641,926	$529,106	0.11%	ADD 2%
49	MARTINGALE ASSET MANAGEMENT L P	41,76341,763	$527,050	0.11%	ADD 13%
50	GREAT LAKES ADVISORS, LLC	41,53141,531	$524,121	0.11%	TRIM -4%
51	BANK OF AMERICA CORP /DE/	39,21239,212	$494,855	0.10%	TRIM -41%
52	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	37,50237,502	$473,275	0.10%	—
53	HSBC HOLDINGS PLC	38,13738,137	$471,755	0.10%	TRIM -8%
54	JANE STREET GROUP, LLC	37,21337,213	$469,628	0.10%	TRIM -57%
55	RHUMBLINE ADVISERS	35,93835,938	$453,528	0.09%	—
56	UBS Group AG	31,98131,981	$403,600	0.08%	ADD 68%
57	ADAR1 Capital Management, LLC	30,50030,500	$384,910	0.08%	NEW
58	BARCLAYS PLC	28,67628,676	$361,892	0.07%	TRIM -57%
59	Brevan Howard Capital Management LP	26,34926,349	$332,524	0.07%	TRIM -45%
60	BRIDGEWAY CAPITAL MANAGEMENT, LLC	25,00025,000	$315,500	0.06%	TRIM -38%
61	DEUTSCHE BANK AG\	24,67924,679	$311,449	0.06%	ADD 19%
62	Creative Planning	22,23022,230	$280,543	0.06%	—
63	Shay Capital LLC	21,54821,548	$271,936	0.06%	NEW
64	SUSQUEHANNA INTERNATIONAL GROUP, LLP	20,31520,315	$256,375	0.05%	ADD 32%
65	ALLIANCEBERNSTEIN L.P.	24,32024,320	$250,010	0.06%	—
66	Allspring Global Investments Holdings, LLC	19,46519,465	$245,648	0.05%	ADD 11%
67	Vanguard Global Advisers, LLC	18,39818,398	$232,183	0.05%	NEW
68	HARBOR CAPITAL ADVISORS, INC.	18,17518,175	$229,000	0.05%	NEW
69	MetLife Investment Management, LLC	17,80217,802	$224,661	0.05%	—
70	CANADA PENSION PLAN INVESTMENT BOARD	17,70017,700	$223,374	0.05%	TRIM -31%
71	Quadrature Capital Ltd	17,53817,538	$221,330	0.05%	TRIM -14%
72	FMR LLC	16,94316,943	$213,820	0.04%	—
73	Dynamic Technology Lab Private Ltd	16,47416,474	$207,902	0.04%	TRIM -35%
74	JPMORGAN CHASE & CO	14,84714,847	$174,749	0.04%	TRIM -79%
75	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	13,57713,577	$171,342	0.03%	ADD 2%
76	ExodusPoint Capital Management, LP	12,06712,067	$152,286	0.03%	TRIM -68%
77	Inscription Capital, LLC	11,83511,835	$149,358	0.03%	—
78	Russell Investments Group, Ltd.	11,63311,633	$146,806	0.03%	—
79	FRANKLIN RESOURCES INC	11,10211,102	$140,107	0.03%	NEW
80	IHT Wealth Management, LLC	11,10011,100	$140,082	0.03%	—
81	WELLS FARGO & COMPANY/MN	11,01111,011	$138,959	0.03%	TRIM -66%
82	Police & Firemen's Retirement System of New Jersey	9,4719,471	$119,524	0.02%	—
83	NEW YORK STATE COMMON RETIREMENT FUND	8,8778,877	$112,028	0.02%	—
84	China Universal Asset Management Co., Ltd.	6,7946,794	$85,740	0.02%	ADD 9%
85	CWM, LLC	6,7886,788	$85,665	0.02%	ADD 221%
86	CITIGROUP INC	4,8534,853	$61,245	0.01%	ADD 18%
87	Versant Capital Management, Inc	4,0464,046	$51,061	0.01%	—
88	Legal & General Group Plc	2,5572,557	$32,269	0.01%	—
89	Ameritas Investment Partners, Inc.	2,4172,417	$30,503	0.01%	—
90	Mirae Asset Global Investments Co., Ltd.	1,9971,997	$25,202	0.01%	ADD 8%
91	Tower Research Capital LLC (TRC)	1,6701,670	$21,075	0.00%	TRIM -14%
92	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	1,5401,540	$19,435	0.00%	TRIM -12%
93	Zurcher Kantonalbank (Zurich Cantonalbank)	1,4171,417	$17,883	0.00%	ADD 228%
94	PNC FINANCIAL SERVICES GROUP, INC.	1,1411,141	$14,400	0.00%	—
95	Sterling Capital Management LLC	943943	$11,901	0.00%	TRIM -43%
96	Arax Advisory Partners	919919	$11,598	0.00%	—
97	GF FUND MANAGEMENT CO. LTD.	852852	$10,752	0.00%	ADD 13%
98	GAMMA Investing LLC	480480	$6,058	0.00%	ADD 405%
99	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	435435	$5,490	0.00%	ADD 1877%
100	EverSource Wealth Advisors, LLC	420420	$5,301	0.00%	ADD 12%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BAKER BROS. ADVISORS LP

4.9M

5.1M

$64M

5AM Venture Management, LLC

4.4M

4.3M

4.1M

$51M

BlackRock, Inc.

2.0M

2.1M

2.4M

$30M

TCG Crossover Management, LLC

585K

2.1M

2.3M

$29M

VANGUARD CAPITAL MANAGEMENT LLC

—

1.3M

$16M

WELLINGTON MANAGEMENT GROUP LLP

1.0M

1.1M

954K

1.0M

$13M

StepStone Group LP

761K

$10M

GEODE CAPITAL MANAGEMENT, LLC

574K

589K

632K

645K

640K

667K

$8M

STATE STREET CORP

505K

494K

496K

499K

509K

534K

$7M

PRICE T ROWE ASSOCIATES INC /MD/

2.9M

2.7M

2.6M

361K

327K

526K

$7M

MILLENNIUM MANAGEMENT LLC

13K

—

170K

837K

498K

519K

$7M

Jones Hill Capital LP

—

374K

$5M

JACOBS LEVY EQUITY MANAGEMENT, INC

213K

211K

221K

316K

363K

334K

$4M

ACADIAN ASSET MANAGEMENT LLC

51K

21K

46K

298K

311K

333K

$4M

DIMENSIONAL FUND ADVISORS LP

217K

327K

424K

394K

273K

324K

$4M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	119	25,477,280	65.6%	$321M
2025-Q4	113	24,448,949	63.0%	$251M
2025-Q3	116	28,609,874	73.7%	$169M
2025-Q2	107	29,603,196	76.3%	$199M
2025-Q1	110	30,241,830	77.9%	$275M
2024-Q4	102	30,666,008	79.0%	$530M
2024-Q3	97	30,110,808	77.6%	$481M
2024-Q2	83	29,678,772	76.5%	$423M
2024-Q1	77	26,250,982	67.6%	$372M
2023-Q4	62	26,345,408	67.9%	$398M
2023-Q3	55	26,035,608	67.1%	$411M

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · TRDA

Activists — 13D, active intent

5AM Ventures V, L.P.10.8%NEWSCHEDULE 13D/A · Amd 1 · event 2025-11-14SEC →

4,123,849 shares · 7 reporting persons

Large holders — 13G, passive (top 5 by % of class)

Holder

% of class

Type

As of

ROCHE FINANCE LTD

6.9%

Exempt

2024-12-31

SEC →

BlackRock, Inc.

5.3%

QII

2024-12-31

SEC →

TCG Crossover GP I, LLC

Passive

2025-11-19

SEC →

JANUS HENDERSON GROUP PLC

TRDA US Equity☆

Institutional ownership· 13F filers holding TRDA · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · TRDA

Institutional ownership· 13F filers holding TRDA · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · TRDA

TRDA US Equity