% of shares outstanding not shown: no SEC cover-page share count falls within 120 days of the 2026-Q1 quarter end, so any percentage would rest on a count that cannot speak for this quarter. Holder share counts are shown as filed.
| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | Lynx1 Capital Management LP | 8,019,1488.0M | $8M | — | — |
| 2 | BVF INC/IL | 5,564,2905.6M | $6M | — | ADD 6% |
| 3 | BAKER BROS. ADVISORS LP | 2,784,7922.8M | $3M | — | — |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 2,154,2562.2M | $2M | — | NEW |
| 5 | BlackRock, Inc. | 1,840,9521.8M | $2M | — | — |
| 6 | MILLENNIUM MANAGEMENT LLC | 1,460,2851.5M | $1M | — | ADD 262% |
| 7 | RENAISSANCE TECHNOLOGIES LLC | 1,364,7831.4M | $1M | — | ADD 20% |
| 8 | Deer Management Co. LLC | 1,245,5041.2M | $1M | — | — |
| 9 | TWO SIGMA INVESTMENTS, LP | 1,209,0091.2M | $1M | — | ADD 86% |
| 10 | Aberdeen Group plc | 918,020918,020 | $927,200 | — | TRIM -49% |
| 11 | JACOBS LEVY EQUITY MANAGEMENT, INC | 808,356808,356 | $816,440 | — | ADD 330% |
| 12 | DC Funds, LP | 630,000630,000 | $630,000 | — | — |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 616,952616,952 | $623,340 | — | ADD 10% |
| 14 | GSA CAPITAL PARTNERS LLP | 378,960378,960 | $383,000 | — | ADD 68% |
| 15 | D. E. Shaw & Co., Inc. | 319,587319,587 | $322,783 | — | ADD 360% |
| 16 | CITADEL ADVISORS LLC | 318,411318,411 | $321,596 | — | ADD 95% |
| 17 | VANGUARD FIDUCIARY TRUST CO | 305,772305,772 | $308,830 | — | NEW |
| 18 | MARSHALL WACE, LLP | 237,346237,346 | $239,719 | — | TRIM -30% |
| 19 | STATE STREET CORP | 207,313207,313 | $209,386 | — | — |
| 20 | ACADIAN ASSET MANAGEMENT LLC | 201,987201,987 | $201,000 | — | ADD 584% |
| 21 | MORGAN STANLEY | 173,643173,643 | $175,379 | — | TRIM -23% |
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 157,228157,228 | $158,800 | — | TRIM -27% |
| 23 | JANE STREET GROUP, LLC | 144,421144,421 | $145,865 | — | TRIM -63% |
| 24 | BROWN BROTHERS HARRIMAN & CO | 143,051143,051 | $144,482 | — | — |
| 25 | Verdad Advisers, LP | 134,001134,001 | $135,341 | — | NEW |
| 26 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 111,900111,900 | $113,019 | — | TRIM -3% |
| 27 | NORTHERN TRUST CORP | 97,44897,448 | $98,422 | — | — |
| 28 | LETKO, BROSSEAU & ASSOCIATES INC | 95,87595,875 | $96,834 | — | — |
| 29 | NewEdge Wealth, LLC | 91,46391,463 | $92,378 | — | — |
| 30 | STIFEL FINANCIAL CORP | 69,40069,400 | $70,094 | — | TRIM -4% |
| 31 | DIMENSIONAL FUND ADVISORS LP | 65,33565,335 | $65,815 | — | TRIM -12% |
| 32 | Kestra Advisory Services, LLC | 62,52562,525 | $63,150 | — | NEW |
| 33 | XTX Topco Ltd | 60,72060,720 | $61,327 | — | TRIM -72% |
| 34 | BANK OF AMERICA CORP /DE/ | 57,52957,529 | $58,104 | — | ADD 49% |
| 35 | AMERIPRISE FINANCIAL INC | 52,63552,635 | $53,161 | — | NEW |
| 36 | NINE MASTS CAPITAL Ltd | 41,74041,740 | $42,157 | — | NEW |
| 37 | GOLDMAN SACHS GROUP INC | 37,26737,267 | $37,640 | — | TRIM -57% |
| 38 | DC Investments Management, LLC | 35,56335,563 | $35,919 | — | — |
| 39 | UBS Group AG | 32,48432,484 | $32,809 | — | TRIM -41% |
| 40 | PRUDENTIAL FINANCIAL INC | 29,80029,800 | $30,098 | — | ADD 22% |
| 41 | PANAGORA ASSET MANAGEMENT INC | 28,79728,797 | $29,085 | — | ADD 14% |
| 42 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 27,70027,700 | $27,977 | — | NEW |
| 43 | HSBC HOLDINGS PLC | 24,57424,574 | $24,439 | — | TRIM -50% |
| 44 | LPL Financial LLC | 22,50022,500 | $22,725 | — | — |
| 45 | Vanguard Personalized Indexing Management, LLC | 21,35921,359 | $21,573 | — | ADD 46% |
| 46 | Virtu Financial LLC | 18,14018,140 | $18,000 | — | NEW |
| 47 | BARCLAYS PLC | 17,08017,080 | $17,251 | — | TRIM -26% |
| 48 | Vanguard Global Advisers, LLC | 15,70515,705 | $15,862 | — | NEW |
| 49 | JPMORGAN CHASE & CO | 16,43616,436 | $15,456 | — | TRIM -51% |
| 50 | Aries Wealth Management | 10,00010,000 | $10,100 | — | — |
| 51 | OSAIC HOLDINGS, INC. | 9,7569,756 | $9,853 | — | TRIM -20% |
| 52 | Tower Research Capital LLC (TRC) | 5,0635,063 | $5,114 | — | TRIM -25% |
| 53 | FEDERATED HERMES, INC. | 4,2954,295 | $4,338 | — | TRIM -14% |
| 54 | FMR LLC | 1,3001,300 | $1,313 | — | ADD 160% |
| 55 | BNP PARIBAS FINANCIAL MARKETS | 713713 | $720 | — | TRIM -97% |
| 56 | SBI Securities Co., Ltd. | 392392 | $396 | — | — |
| 57 | Strategic Wealth Partners, Ltd. | 311311 | $314 | — | — |
| 58 | Caitong International Asset Management Co., Ltd | 22 | $2 | — | NEW |
| 59 | CITIGROUP INC | 11 | $1 | — | NEW |
| 60 | ROYAL BANK OF CANADA | 7373 | $0 | — | TRIM -80% |
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| Lynx1 Capital Management LP | 5.4M | 5.4M | 7.9M | 7.9M | 8.0M | 8.0M | $8M |
| BVF INC/IL | 3.0M | 4.9M | 5.2M | 5.2M | 5.2M | 5.6M | $6M |
| BAKER BROS. ADVISORS LP | 2.8M | 2.8M | 2.8M | 2.8M | 2.8M | 2.8M | $3M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 2.2M | $2M |
| BlackRock, Inc. | 5.0M | 4.9M | 2.6M | 2.4M | 1.8M | 1.8M | $2M |
| MILLENNIUM MANAGEMENT LLC | — | 231K | 630K | 466K | 404K | 1.5M | $1M |
| RENAISSANCE TECHNOLOGIES LLC | 11K | 170K | 792K | 830K | 1.1M | 1.4M | $1M |
| Deer Management Co. LLC | 1.2M | 1.2M | 1.2M | 1.2M | 1.2M | 1.2M | $1M |
| TWO SIGMA INVESTMENTS, LP | — | 90K | 365K | 419K | 651K | 1.2M | $1M |
| Aberdeen Group plc | 884K | 891K | 891K | 1.4M | 1.8M | 918K | $927,200 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 19K | — | — | — | 188K | 808K | $816,440 |
| DC Funds, LP | 630K | 630K | 630K | 630K | 630K | 630K | $630,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 963K | 1.0M | 566K | 568K | 562K | 617K | $623,340 |
| GSA CAPITAL PARTNERS LLP | — | 42K | — | — | 226K | 379K | $383,000 |
| D. E. Shaw & Co., Inc. | — | — | — | — | 69K | 320K | $322,783 |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding divides each quarter's as-filed 13F shares by the SEC cover-page share count dated to that same quarter (split-adjusted), not by today's count — so splits and buybacks don't move the line.
| Quarter | Holders | Shares held | % shares out |
|---|
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
| Biggest buyers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD CAPITAL MANAGEMENT LLC | +2,154,256 | $2M | OPEN |
| MILLENNIUM MANAGEMENT LLC | +1,056,667 | $1M | ADD |
| JACOBS LEVY EQUITY MANAGEMENT, INC | +620,204 | $626,406 | ADD |
| TWO SIGMA INVESTMENTS, LP | +557,830 | $563,408 | ADD |
| BVF INC/IL | +338,216 | $341,598 | ADD |
| Biggest sellers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD GROUP INC | −2,475,733 | $3M | CLOSE |
| Aberdeen Group plc | −867,221 | $875,893 | TRIM |
| TWO SIGMA ADVISERS, LP | −353,900 | $357,439 | CLOSE |
| JANE STREET GROUP, LLC | −243,863 | $246,302 | TRIM |
| XTX Topco Ltd | −158,281 | $159,864 | TRIM |
The 2025-Q4 register is as-filed in ITS OWN share basis; every count below was rebased into the 2026-Q1 basis (no split in between, factor 1). Dollar figures value the SHARE delta at one price — the 2026-03-31 close — rather than differencing two filings' own reported values, which would mix the quarter's price move into the trade figure.
13Fs disclose LONG US-listed positions only — shorts, most derivatives, bonds and non-US listings are invisible here, and a filer's quarter-over-quarter change is not necessarily a trade (index rebalances, in-kind transfers and entity successions all read as flow).
| Value held |
|---|
| 2026-Q1 | 60 | 32,503,948 | — | $33M |
| 2025-Q4 | 61 | 30,718,552 | — | $31M |
| 2025-Q3 | 73 | 34,941,091 | — | $64M |
| 2025-Q2 | 81 | 35,725,028 | — | $52M |
| 2025-Q1 | 92 | 40,135,892 | — | $55M |
| 2024-Q4 | 89 | 41,522,870 | — | $126M |
| 2024-Q3 | 89 | 41,867,329 | — | $209M |
| 2024-Q2 | 80 | 41,467,503 | — | $243M |
| 2024-Q1 | 66 | 34,807,858 | — | $276M |
| 2023-Q4 | 54 | 32,180,822 | — | $188M |
| 2023-Q3 | 32 | 28,588,231 | — | $73M |
| 2023-Q2 | 28 | 27,951,619 | — | $70M |
| 2023-Q1 | 28 | 9,667,555 | — | $20M |
| 2022-Q4 | 28 | 9,519,313 | — | $15M |
| 2022-Q3 | 26 | 9,508,348 | — | $29M |
| 2022-Q2 | 24 | 9,682,128 | 7.5% | $30M |
| 2022-Q1 | 25 | 9,407,737 | 7.2% | $26M |
| 2021-Q4 | 29 | 9,861,992 | 7.6% | $44M |
| 2021-Q3 | 27 | 10,134,980 | — | $83M |
