STTK US Equity

Shattuck Labs, Inc.

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Health Care · Pharmaceutical Preparations · CIK 1680367 · FYE 1231

$6.76

-0.06 (-0.88%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding STTK · 2026-Q1 methodology → sources →

84 holders

% of shares outstanding held

73.1%

Shares held (13F)

56,070,181

Reporting holders

Top holders

largest 84 of 84 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	T. Rowe Price Investment Management, Inc.	9,865,5589.9M	$63M	12.87%	ADD 430%
2	ORBIMED ADVISORS LLC	6,306,1276.3M	$41M	8.22%	—
3	Redmile Group, LLC	5,539,7245.5M	$36M	7.22%	—
4	Prosight Management, LP	5,004,4395.0M	$32M	6.53%	ADD 110%
5	ADAGE CAPITAL PARTNERS GP, L.L.C.	4,644,9574.6M	$30M	6.06%	TRIM -26%
6	NEXTBio Capital Management LP	3,149,9073.1M	$20M	4.11%	—
7	VANGUARD CAPITAL MANAGEMENT LLC	2,277,1762.3M	$15M	2.97%	NEW†
8	PRICE T ROWE ASSOCIATES INC /MD/	1,782,7881.8M	$11M	2.32%	TRIM -7%
9	CLARK ESTATES INC/NY	1,475,6481.5M	$9M	1.92%	—
10	PINNACLE ASSOCIATES LTD	1,368,2231.4M	$9M	1.78%	—
11	Aberdeen Group plc	1,159,3211.2M	$7M	1.51%	ADD 118%
12	Point72 Asset Management, L.P.	1,031,0491.0M	$7M	1.34%	TRIM -3%
13	AMERIPRISE FINANCIAL INC	905,707905,707	$6M	1.18%	ADD 7776%
14	683 Capital Management, LLC	800,000800,000	$5M	1.04%	TRIM -42%
15	MILLENNIUM MANAGEMENT LLC	763,745763,745	$5M	1.00%	ADD 60%
16	SUSQUEHANNA INTERNATIONAL GROUP, LLP	715,965715,965	$5M	0.93%	ADD 382%
17	GEODE CAPITAL MANAGEMENT, LLC	645,705645,705	$4M	0.84%	ADD 4%
18	RENAISSANCE TECHNOLOGIES LLC	604,500604,500	$4M	0.79%	ADD 77%
19	MARSHALL WACE, LLP	581,471581,471	$4M	0.76%	ADD 19%
20	BlackRock, Inc.	510,806510,806	$3M	0.67%	ADD 22%
21	S&G Foundation	435,749435,749	$3M	0.57%	NEW
22	JANE STREET GROUP, LLC	415,938415,938	$3M	0.54%	ADD 670%
23	FMR LLC	392,500392,500	$3M	0.51%	—
24	TD Asset Management Inc	382,648382,648	$2M	0.50%	ADD 52%
25	VANGUARD FIDUCIARY TRUST CO	324,588324,588	$2M	0.42%	NEW
26	TWO SIGMA INVESTMENTS, LP	316,012316,012	$2M	0.41%	TRIM -28%
27	DIADEMA PARTNERS LP	293,664293,664	$2M	0.38%	NEW
28	ALGERT GLOBAL LLC	286,072286,072	$2M	0.37%	NEW
29	SPHERA FUNDS MANAGEMENT LTD.	280,786280,786	$2M	0.37%	ADD 44%
30	STATE STREET CORP	263,768263,768	$2M	0.34%	ADD 22%
31	Hudson Bay Capital Management LP	228,817228,817	$1M	0.30%	NEW
32	MORGAN STANLEY	200,136200,136	$1M	0.26%	ADD 1005%
33	DEUTSCHE BANK AG\	194,773194,773	$1M	0.25%	NEW
34	GOLDMAN SACHS GROUP INC	191,442191,442	$1M	0.25%	ADD 49%
35	ACADIAN ASSET MANAGEMENT LLC	183,246183,246	$1M	0.24%	ADD 131%
36	DIMENSIONAL FUND ADVISORS LP	155,642155,642	$1M	0.20%	ADD 571%
37	CITADEL ADVISORS LLC	148,021148,021	$951,775	0.19%	ADD 115%
38	XTX Topco Ltd	142,466142,466	$916,056	0.19%	ADD 473%
39	MANUFACTURERS LIFE INSURANCE COMPANY, THE	142,300142,300	$914,989	0.19%	ADD 5%
40	Connor, Clark & Lunn Investment Management Ltd.	139,304139,304	$895,725	0.18%	ADD 112%
41	Qube Research & Technologies Ltd	126,798126,798	$815,311	0.17%	ADD 227%
42	NORTHERN TRUST CORP	126,061126,061	$810,572	0.16%	TRIM -13%
43	BARCLAYS PLC	119,879119,879	$770,822	0.16%	NEW
44	HRT FINANCIAL LP	90,69890,698	$583,000	0.12%	NEW
45	Bank of New York Mellon Corp	89,77489,774	$577,246	0.12%	TRIM -19%
46	BANK OF AMERICA CORP /DE/	79,92479,924	$513,911	0.10%	TRIM -93%
47	Brevan Howard Capital Management LP	79,47679,476	$511,031	0.10%	NEW
48	LBJ Family Wealth Advisors, Ltd.	82,17782,177	$490,000	0.11%	—
49	CITIGROUP INC	75,00575,005	$482,282	0.10%	ADD 202%
50	Persistent Asset Partners Ltd	74,22974,229	$477,292	0.10%	NEW
51	Pathstone Holdings, LLC	73,95673,956	$475,538	0.10%	TRIM -53%
52	Hillsdale Investment Management Inc.	65,40065,400	$420,522	0.09%	NEW
53	Davis Asset Management, L.P.	48,27648,276	$310,415	0.06%	NEW
54	AMERICAN CENTURY COMPANIES INC	48,12748,127	$309,457	0.06%	ADD 178%
55	BRIDGEWAY CAPITAL MANAGEMENT, LLC	42,30042,300	$271,989	0.06%	—
56	HSBC HOLDINGS PLC	42,44542,445	$268,677	0.06%	NEW
57	EP Wealth Advisors, LLC	41,16741,167	$264,704	0.05%	—
58	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	40,88140,881	$262,865	0.05%	ADD 96%
59	PIPER SANDLER & CO.	39,46739,467	$253,773	0.05%	—
60	Invesco Ltd.	36,93236,932	$237,473	0.05%	ADD 31%
61	UBS Group AG	36,28036,280	$233,281	0.05%	ADD 175%
62	OMERS ADMINISTRATION Corp	33,30033,300	$214,119	0.04%	ADD 26%
63	Squarepoint Ops LLC	31,16231,162	$200,372	0.04%	TRIM -52%
64	Dynamic Technology Lab Private Ltd	29,58829,588	$190,251	0.04%	NEW
65	Vanguard Global Advisers, LLC	26,29526,295	$169,077	0.03%	NEW
66	RITHOLTZ WEALTH MANAGEMENT	26,00026,000	$167,180	0.03%	—
67	Jump Financial, LLC	24,68624,686	$158,730	0.03%	NEW
68	BENJAMIN EDWARDS INC	23,40023,400	$150,462	0.03%	NEW
69	Mallini Complete Financial Planning LLC	22,63222,632	$145,523	0.03%	—
70	CHOREO, LLC	27,25127,251	$130,182	0.04%	—
71	Diametric Capital, LP	18,43418,434	$118,530	0.02%	NEW
72	Catalyst Funds Management Pty Ltd	17,90017,900	$115,097	0.02%	NEW
73	Engineers Gate Manager LP	16,08716,087	$103,439	0.02%	ADD 18%
74	Verdad Advisers, LP	13,37813,378	$86,021	0.02%	NEW
75	Creative Planning	12,33512,335	$79,314	0.02%	—
76	Quadrature Capital Ltd	12,13412,134	$78,022	0.02%	NEW
77	Schonfeld Strategic Advisors LLC	11,53311,533	$74,156	0.02%	NEW
78	US BANCORP \DE\	8,0108,010	$51,504	0.01%	NEW
79	BNP PARIBAS FINANCIAL MARKETS	5,6405,640	$36,265	0.01%	ADD 944%
80	JPMORGAN CHASE & CO	248248	$1,478	0.00%	TRIM -28%
81	Optiver Holding B.V.	6666	$424	0.00%	—
82	SBI Securities Co., Ltd.	5050	$322	0.00%	TRIM -46%
83	CWM, LLC	3939	$251	0.00%	TRIM -9%
84	ROYAL BANK OF CANADA	7373	$0	0.00%	ADD 14%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

T. Rowe Price Investment Management, Inc.

—

1.9M

9.9M

$63M

ORBIMED ADVISORS LLC

—

6.3M

$41M

Redmile Group, LLC

5.5M

$36M

Prosight Management, LP

6.6M

5.5M

2.4M

5.0M

$32M

ADAGE CAPITAL PARTNERS GP, L.L.C.

4.7M

6.3M

4.6M

$30M

NEXTBio Capital Management LP

—

3.1M

$20M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.3M

$15M

PRICE T ROWE ASSOCIATES INC /MD/

13K

—

1.9M

1.8M

$11M

CLARK ESTATES INC/NY

1.5M

$9M

PINNACLE ASSOCIATES LTD

1.3M

1.4M

$9M

Aberdeen Group plc

—

95K

531K

1.2M

$7M

Point72 Asset Management, L.P.

—

1.1M

1.0M

$7M

AMERIPRISE FINANCIAL INC

—

12K

906K

$6M

683 Capital Management, LLC

1.1M

1.5M

1.4M

800K

$5M

MILLENNIUM MANAGEMENT LLC

201K

303K

843K

691K

477K

764K

$5M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	84	56,070,181	73.1%	$360M
2025-Q4	65	42,533,435	55.5%	$155M
2025-Q3	56	36,388,147	47.5%	$87M
2025-Q2	61	28,687,807	37.4%	$23M
2025-Q1	75	31,188,157	40.7%	$30M
2024-Q4	75	31,632,725	41.3%	$38M
2024-Q3	78	36,319,843	47.4%	$125M
2024-Q2	74	34,194,939	44.6%	$132M
2024-Q1	70	31,671,856	41.3%	$283M
2023-Q4	57	29,157,153	38.0%	$208M

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · STTK

Activists — 13D, active intent

Redmile Group, LLC9.9%NEWSCHEDULE 13D/A · Amd 6 · event 2026-07-15SEC →

10,019,421 shares · 3 reporting persons

Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).

Institutional ownership· 13F filers holding STTK · 2026-Q1 methodology → sources →

84 holders

% of shares outstanding held

73.1%

Shares held (13F)

56,070,181

Reporting holders

Top holders

largest 84 of 84 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	T. Rowe Price Investment Management, Inc.	9,865,5589.9M	$63M	12.87%	ADD 430%
2	ORBIMED ADVISORS LLC	6,306,1276.3M	$41M	8.22%	—
3	Redmile Group, LLC	5,539,7245.5M	$36M	7.22%	—
4	Prosight Management, LP	5,004,4395.0M	$32M	6.53%	ADD 110%
5	ADAGE CAPITAL PARTNERS GP, L.L.C.	4,644,9574.6M	$30M	6.06%	TRIM -26%
6	NEXTBio Capital Management LP	3,149,9073.1M	$20M	4.11%	—
7	VANGUARD CAPITAL MANAGEMENT LLC	2,277,1762.3M	$15M	2.97%	NEW†
8	PRICE T ROWE ASSOCIATES INC /MD/	1,782,7881.8M	$11M	2.32%	TRIM -7%
9	CLARK ESTATES INC/NY	1,475,6481.5M	$9M	1.92%	—
10	PINNACLE ASSOCIATES LTD	1,368,2231.4M	$9M	1.78%	—
11	Aberdeen Group plc	1,159,3211.2M	$7M	1.51%	ADD 118%
12	Point72 Asset Management, L.P.	1,031,0491.0M	$7M	1.34%	TRIM -3%
13	AMERIPRISE FINANCIAL INC	905,707905,707	$6M	1.18%	ADD 7776%
14	683 Capital Management, LLC	800,000800,000	$5M	1.04%	TRIM -42%
15	MILLENNIUM MANAGEMENT LLC	763,745763,745	$5M	1.00%	ADD 60%
16	SUSQUEHANNA INTERNATIONAL GROUP, LLP	715,965715,965	$5M	0.93%	ADD 382%
17	GEODE CAPITAL MANAGEMENT, LLC	645,705645,705	$4M	0.84%	ADD 4%
18	RENAISSANCE TECHNOLOGIES LLC	604,500604,500	$4M	0.79%	ADD 77%
19	MARSHALL WACE, LLP	581,471581,471	$4M	0.76%	ADD 19%
20	BlackRock, Inc.	510,806510,806	$3M	0.67%	ADD 22%
21	S&G Foundation	435,749435,749	$3M	0.57%	NEW
22	JANE STREET GROUP, LLC	415,938415,938	$3M	0.54%	ADD 670%
23	FMR LLC	392,500392,500	$3M	0.51%	—
24	TD Asset Management Inc	382,648382,648	$2M	0.50%	ADD 52%
25	VANGUARD FIDUCIARY TRUST CO	324,588324,588	$2M	0.42%	NEW
26	TWO SIGMA INVESTMENTS, LP	316,012316,012	$2M	0.41%	TRIM -28%
27	DIADEMA PARTNERS LP	293,664293,664	$2M	0.38%	NEW
28	ALGERT GLOBAL LLC	286,072286,072	$2M	0.37%	NEW
29	SPHERA FUNDS MANAGEMENT LTD.	280,786280,786	$2M	0.37%	ADD 44%
30	STATE STREET CORP	263,768263,768	$2M	0.34%	ADD 22%
31	Hudson Bay Capital Management LP	228,817228,817	$1M	0.30%	NEW
32	MORGAN STANLEY	200,136200,136	$1M	0.26%	ADD 1005%
33	DEUTSCHE BANK AG\	194,773194,773	$1M	0.25%	NEW
34	GOLDMAN SACHS GROUP INC	191,442191,442	$1M	0.25%	ADD 49%
35	ACADIAN ASSET MANAGEMENT LLC	183,246183,246	$1M	0.24%	ADD 131%
36	DIMENSIONAL FUND ADVISORS LP	155,642155,642	$1M	0.20%	ADD 571%
37	CITADEL ADVISORS LLC	148,021148,021	$951,775	0.19%	ADD 115%
38	XTX Topco Ltd	142,466142,466	$916,056	0.19%	ADD 473%
39	MANUFACTURERS LIFE INSURANCE COMPANY, THE	142,300142,300	$914,989	0.19%	ADD 5%
40	Connor, Clark & Lunn Investment Management Ltd.	139,304139,304	$895,725	0.18%	ADD 112%
41	Qube Research & Technologies Ltd	126,798126,798	$815,311	0.17%	ADD 227%
42	NORTHERN TRUST CORP	126,061126,061	$810,572	0.16%	TRIM -13%
43	BARCLAYS PLC	119,879119,879	$770,822	0.16%	NEW
44	HRT FINANCIAL LP	90,69890,698	$583,000	0.12%	NEW
45	Bank of New York Mellon Corp	89,77489,774	$577,246	0.12%	TRIM -19%
46	BANK OF AMERICA CORP /DE/	79,92479,924	$513,911	0.10%	TRIM -93%
47	Brevan Howard Capital Management LP	79,47679,476	$511,031	0.10%	NEW
48	LBJ Family Wealth Advisors, Ltd.	82,17782,177	$490,000	0.11%	—
49	CITIGROUP INC	75,00575,005	$482,282	0.10%	ADD 202%
50	Persistent Asset Partners Ltd	74,22974,229	$477,292	0.10%	NEW
51	Pathstone Holdings, LLC	73,95673,956	$475,538	0.10%	TRIM -53%
52	Hillsdale Investment Management Inc.	65,40065,400	$420,522	0.09%	NEW
53	Davis Asset Management, L.P.	48,27648,276	$310,415	0.06%	NEW
54	AMERICAN CENTURY COMPANIES INC	48,12748,127	$309,457	0.06%	ADD 178%
55	BRIDGEWAY CAPITAL MANAGEMENT, LLC	42,30042,300	$271,989	0.06%	—
56	HSBC HOLDINGS PLC	42,44542,445	$268,677	0.06%	NEW
57	EP Wealth Advisors, LLC	41,16741,167	$264,704	0.05%	—
58	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	40,88140,881	$262,865	0.05%	ADD 96%
59	PIPER SANDLER & CO.	39,46739,467	$253,773	0.05%	—
60	Invesco Ltd.	36,93236,932	$237,473	0.05%	ADD 31%
61	UBS Group AG	36,28036,280	$233,281	0.05%	ADD 175%
62	OMERS ADMINISTRATION Corp	33,30033,300	$214,119	0.04%	ADD 26%
63	Squarepoint Ops LLC	31,16231,162	$200,372	0.04%	TRIM -52%
64	Dynamic Technology Lab Private Ltd	29,58829,588	$190,251	0.04%	NEW
65	Vanguard Global Advisers, LLC	26,29526,295	$169,077	0.03%	NEW
66	RITHOLTZ WEALTH MANAGEMENT	26,00026,000	$167,180	0.03%	—
67	Jump Financial, LLC	24,68624,686	$158,730	0.03%	NEW
68	BENJAMIN EDWARDS INC	23,40023,400	$150,462	0.03%	NEW
69	Mallini Complete Financial Planning LLC	22,63222,632	$145,523	0.03%	—
70	CHOREO, LLC	27,25127,251	$130,182	0.04%	—
71	Diametric Capital, LP	18,43418,434	$118,530	0.02%	NEW
72	Catalyst Funds Management Pty Ltd	17,90017,900	$115,097	0.02%	NEW
73	Engineers Gate Manager LP	16,08716,087	$103,439	0.02%	ADD 18%
74	Verdad Advisers, LP	13,37813,378	$86,021	0.02%	NEW
75	Creative Planning	12,33512,335	$79,314	0.02%	—
76	Quadrature Capital Ltd	12,13412,134	$78,022	0.02%	NEW
77	Schonfeld Strategic Advisors LLC	11,53311,533	$74,156	0.02%	NEW
78	US BANCORP \DE\	8,0108,010	$51,504	0.01%	NEW
79	BNP PARIBAS FINANCIAL MARKETS	5,6405,640	$36,265	0.01%	ADD 944%
80	JPMORGAN CHASE & CO	248248	$1,478	0.00%	TRIM -28%
81	Optiver Holding B.V.	6666	$424	0.00%	—
82	SBI Securities Co., Ltd.	5050	$322	0.00%	TRIM -46%
83	CWM, LLC	3939	$251	0.00%	TRIM -9%
84	ROYAL BANK OF CANADA	7373	$0	0.00%	ADD 14%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

T. Rowe Price Investment Management, Inc.

—

1.9M

9.9M

$63M

ORBIMED ADVISORS LLC

—

6.3M

$41M

Redmile Group, LLC

5.5M

$36M

Prosight Management, LP

6.6M

5.5M

2.4M

5.0M

$32M

ADAGE CAPITAL PARTNERS GP, L.L.C.

4.7M

6.3M

4.6M

$30M

NEXTBio Capital Management LP

—

3.1M

$20M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.3M

$15M

PRICE T ROWE ASSOCIATES INC /MD/

13K

—

1.9M

1.8M

$11M

CLARK ESTATES INC/NY

1.5M

$9M

PINNACLE ASSOCIATES LTD

1.3M

1.4M

$9M

Aberdeen Group plc

—

95K

531K

1.2M

$7M

Point72 Asset Management, L.P.

—

1.1M

1.0M

$7M

AMERIPRISE FINANCIAL INC

—

12K

906K

$6M

683 Capital Management, LLC

1.1M

1.5M

1.4M

800K

$5M

MILLENNIUM MANAGEMENT LLC

201K

303K

843K

691K

477K

764K

$5M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	84	56,070,181	73.1%	$360M
2025-Q4	65	42,533,435	55.5%	$155M
2025-Q3	56	36,388,147	47.5%	$87M
2025-Q2	61	28,687,807	37.4%	$23M
2025-Q1	75	31,188,157	40.7%	$30M
2024-Q4	75	31,632,725	41.3%	$38M
2024-Q3	78	36,319,843	47.4%	$125M
2024-Q2	74	34,194,939	44.6%	$132M
2024-Q1	70	31,671,856	41.3%	$283M
2023-Q4	57	29,157,153	38.0%	$208M

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · STTK

Activists — 13D, active intent

Redmile Group, LLC9.9%NEWSCHEDULE 13D/A · Amd 6 · event 2026-07-15SEC →

10,019,421 shares · 3 reporting persons

STTK US Equity☆

Institutional ownership· 13F filers holding STTK · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · STTK

Institutional ownership· 13F filers holding STTK · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · STTK

STTK US Equity