Institutional holders Insiders (Form 4) Congress
% of shares outstanding held
45.9%
Shares held (13F)
16,130,046
Top holders largest 39 of 39 · Δ vs 2025-Q4 # Holder Shares Value % of shares out Δ QoQ 1 1 5AM Venture Management, LLC 9,681,763 9.7M $6M 27.55% — 2 2 Versant Venture Management, LLC 2,007,704 2.0M $1M 5.71% — 3 3 BAKER BROS. ADVISORS LP 1,575,243 1.6M $968,144 4.48% ADD 9% 4 4 VANGUARD CAPITAL MANAGEMENT LLC 764,457 764,457 $470,141 2.18% NEW † 5 5 SPHERA FUNDS MANAGEMENT LTD. 678,928 678,928 $417,269 1.93% ADD 42% 6 6 BlackRock, Inc. 286,131 286,131 $175,855 0.81% — 7 7 GEODE CAPITAL MANAGEMENT, LLC 277,256 277,256 $170,447 0.79% ADD 32% 8 8 MILLENNIUM MANAGEMENT LLC 258,200 258,200 $158,690 0.73% TRIM -32% 9 9 PLATINUM INVESTMENT MANAGEMENT LTD 233,095 233,095 $143,260 0.66% — 10 10 VANGUARD FIDUCIARY TRUST CO 104,229 104,229 $64,101 0.30% NEW 11 11 STATE STREET CORP 75,326 75,326 $46,295 0.21% — 12 12 UBS Group AG 45,762 45,762 $28,143 0.13% ADD 244% 13 13 XTX Topco Ltd 40,919 40,919 $25,149 0.12% TRIM -23% 14 14 TWO SIGMA INVESTMENTS, LP 25,684 25,684 $15,785 0.07% TRIM -50% 15 15 Engineers Gate Manager LP 20,194 20,194 $12,411 0.06% TRIM -13% 16 16 NORTHERN TRUST CORP 20,142 20,142 $12,379 0.06% — 17 17 BARCLAYS PLC 18,089 18,089 $11,117 0.05% TRIM -15% 18 18 GROUP ONE TRADING LLC 7,205 7,205 $4,428 0.02% TRIM -59% 19 19 Vanguard Global Advisers, LLC 4,557 4,557 $2,803 0.01% NEW 20 20 MORGAN STANLEY 2,549 2,549 $1,567 0.01% TRIM -40% 21 21 FEDERATED HERMES, INC. 1,158 1,158 $712 0.00% — 22 22 OSAIC HOLDINGS, INC. 600 600 $364 0.00% ADD 29900% 23 23 NATIONAL BANK OF CANADA /FI/ 400 400 $242 0.00% — 24 24 TD Waterhouse Canada Inc. 79 79 $51 0.00% ADD 216% 25 25 JPMORGAN CHASE & CO 66 66 $39 0.00% — 26 26 Zurcher Kantonalbank (Zurich Cantonalbank) 52 52 $32 0.00% — 27 27 Federation des caisses Desjardins du Quebec 51 51 $31 0.00% — 28 28 Rockefeller Capital Management L.P. 39 39 $24 0.00% — 29 29 Optiver Holding B.V. 20 20 $12 0.00% — 30 30 CoreCap Advisors, LLC 8 8 $5 0.00% — 31 31 Plante Moran Financial Advisors, LLC 3 3 $2 0.00% — 32 32 HARBOUR INVESTMENTS, INC. 1 1 $1 0.00% — 33 33 CITIGROUP INC 2 2 $1 0.00% NEW 34 34 IFP Advisors, Inc 2 2 $1 0.00% ADD 100% 35 35 NFSG Corp 1 1 $1 0.00% TRIM -94% 36 36 Leo H. Evart, Inc. 1 1 $1 0.00% NEW 37 37 PFS Partners, LLC 1 1 $1 0.00% — 38 38 MCGUIRE CAPITAL ADVISORS INC 2 2 $1 0.00% — 39 39 ROYAL BANK OF CANADA 127 127 $0 0.00% ADD 2%
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
Holder trends· top 15 holders · shares held over 6 quarters green added · red trimmed6 12 24 Max
Holder 2024-Q4 2025-Q1 2025-Q2 2025-Q3 2025-Q4 2026-Q1 Latest value 5AM Venture Management, LLC 9.9M 9.9M 9.9M 9.7M 9.7M 9.7M $6M Versant Venture Management, LLC 2.0M 2.0M 2.0M 2.0M 2.0M 2.0M $1M BAKER BROS. ADVISORS LP 1.5M 1.5M 1.5M 1.5M 1.5M 1.6M $968,144 VANGUARD CAPITAL MANAGEMENT LLC — — — — — 764K $470,141 SPHERA FUNDS MANAGEMENT LTD. 1.6M 1.5M 538K 479K 479K 679K $417,269 BlackRock, Inc. 1.2M 1.2M 413K 280K 282K 286K $175,855 GEODE CAPITAL MANAGEMENT, LLC 406K 441K 202K 209K 210K 277K $170,447 MILLENNIUM MANAGEMENT LLC — — 471K 402K 380K 258K $158,690 PLATINUM INVESTMENT MANAGEMENT LTD 434K 293K 293K 233K 233K 233K $143,260 VANGUARD FIDUCIARY TRUST CO — — — — — 104K $64,101 STATE STREET CORP 375K 370K 67K 75K 75K 75K $46,295 UBS Group AG 60K 152K 42K 30K 13K 46K $28,143 XTX Topco Ltd — — — — 53K 41K $25,149 TWO SIGMA INVESTMENTS, LP — 17K 63K 92K 52K 26K $15,785 Engineers Gate Manager LP — — — — 23K 20K $12,411
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Institutional footprint by quarter % of shares outstanding held 73.5% 0.0% reporting 13F holders 75 1 2021-Q1 2026-Q1 2021-Q1 · 1 holders · 0.1% of shares out 2022-Q4 · 3 holders · 0.1% of shares out 2023-Q1 · 1 holders · 0.0% of shares out 2023-Q2 · 1 holders · 0.0% of shares out 2023-Q4 · 1 holders · 0.0% of shares out 2024-Q1 · 3 holders · 5.7% of shares out 2024-Q2 · 62 holders · 73.5% of shares out 2024-Q3 · 74 holders · 73.2% of shares out 2024-Q4 · 73 holders · 71.7% of shares out 2025-Q1 · 75 holders · 70.3% of shares out 2025-Q2 · 58 holders · 58.0% of shares out 2025-Q3 · 58 holders · 56.6% of shares out 2025-Q4 · 50 holders · 45.9% of shares out 2026-Q1 · 39 holders · 45.9% of shares out Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).
Quarter Holders Shares held % shares out Value held 2026-Q1 39 16,130,046 45.9% $10M 2025-Q4 50 16,131,790 45.9% $12M 2025-Q3 58 19,883,381 56.6% $78M 2025-Q2 58 20,399,797 58.0% $85M 2025-Q1 75 24,700,758 70.3% $39M 2024-Q4 73 25,208,465 71.7% $71M 2024-Q3 74 25,741,482 73.2% $101M 2024-Q2 62 25,813,223 73.5% $207M 2024-Q1 3 2,010,903 5.7% $31M 2023-Q4 1 1,600 0.0% $4,352 2023-Q2 1 11,900 0.0% $253 2023-Q1 1 11,900 0.0% $207 2022-Q4 3
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
