| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | GILEAD SCIENCES, INC. | 31,424,76031.4M | $679M | 25.07% | — |
| 2 | BlackRock, Inc. | 15,226,47515.2M | $329M | 12.15% | — |
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 6,089,5166.1M | $132M | 4.86% | ADD 17% |
| 4 | STATE STREET CORP | 5,412,9015.4M | $117M | 4.32% | ADD 18% |
| 5 | SUVRETTA CAPITAL MANAGEMENT, LLC | 5,030,9935.0M | $109M | 4.01% | TRIM -3% |
| 6 | VANGUARD PORTFOLIO MANAGEMENT LLC | 4,272,0564.3M | $92M | 3.41% | NEW† |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 3,856,7253.9M | $83M | 3.08% | NEW† |
| 8 | Woodline Partners LP | 3,777,7983.8M | $82M | 3.01% | — |
| 9 | MARSHALL WACE, LLP | 3,761,4373.8M | $81M | 3.00% | ADD 11% |
| 10 | Siren, L.L.C. | 3,007,0773.0M | $65M | 2.40% | — |
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 2,252,3672.3M | $49M | 1.80% | ADD 18% |
| 12 | Fisher Asset Management, LLC | 2,190,4042.2M | $47M | 1.75% | ADD 12% |
| 13 | SAMLYN CAPITAL, LLC | 1,908,4121.9M | $41M | 1.52% | ADD 19% |
| 14 | BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,654,7541.7M | $36M | 1.32% | — |
| 15 | DIMENSIONAL FUND ADVISORS LP | 1,426,2231.4M | $31M | 1.14% | TRIM -6% |
| 16 | CITADEL ADVISORS LLC | 1,329,9351.3M | $29M | 1.06% | ADD 1170% |
| 17 | Parkman Healthcare Partners LLC | 1,207,2741.2M | $26M | 0.96% | ADD 25% |
| 18 | Logos Global Management LP | 1,200,0001.2M | $26M | 0.96% | NEW |
| 19 | FMR LLC | 1,165,2521.2M | $25M | 0.93% | ADD 3% |
| 20 | MORGAN STANLEY | 1,113,5261.1M | $24M | 0.89% | TRIM -8% |
| 21 | Trails Edge Capital Partners, LP | 1,047,9351.0M | $23M | 0.84% | ADD 14% |
| 22 | GOLDMAN SACHS GROUP INC | 999,786999,786 | $22M | 0.80% | TRIM -14% |
| 23 | Sofinnova Investments, Inc. | 923,086923,086 | $20M | 0.74% | TRIM -16% |
| 24 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 903,638903,638 | $20M | 0.72% | TRIM -7% |
| 25 | NORTHERN TRUST CORP | 840,305840,305 | $18M | 0.67% | ADD 6% |
| 26 | Invesco Ltd. | 820,820820,820 | $18M | 0.65% | ADD 98% |
| 27 | Candriam S.C.A. | 790,613790,613 | $17M | 0.63% | — |
| 28 | Aberdeen Group plc | 769,787769,787 | $17M | 0.61% | ADD 100% |
| 29 | BANK OF AMERICA CORP /DE/ | 646,068646,068 | $14M | 0.52% | TRIM -35% |
| 30 | VANGUARD FIDUCIARY TRUST CO | 582,920582,920 | $13M | 0.47% | NEW |
| 31 | Bank of New York Mellon Corp | 511,166511,166 | $11M | 0.41% | — |
| 32 | Decheng Capital LLC | 477,819477,819 | $10M | 0.38% | TRIM -12% |
| 33 | Soleus Capital Management, L.P. | 451,983451,983 | $10M | 0.36% | TRIM -37% |
| 34 | DAFNA Capital Management LLC | 443,829443,829 | $10M | 0.35% | ADD 3% |
| 35 | JACOBS LEVY EQUITY MANAGEMENT, INC | 430,346430,346 | $9M | 0.34% | TRIM -54% |
| 36 | RENAISSANCE TECHNOLOGIES LLC | 424,700424,700 | $9M | 0.34% | ADD 1199% |
| 37 | BAKER BROS. ADVISORS LP | 415,621415,621 | $9M | 0.33% | ADD 54% |
| 38 | PRINCIPAL FINANCIAL GROUP INC | 413,778413,778 | $9M | 0.33% | — |
| 39 | PDT Partners, LLC | 388,338388,338 | $8M | 0.31% | — |
| 40 | BNP PARIBAS FINANCIAL MARKETS | 381,856381,856 | $8M | 0.30% | TRIM -10% |
| 41 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 379,100379,100 | $8M | 0.30% | — |
| 42 | Hudson Bay Capital Management LP | 356,535356,535 | $8M | 0.28% | ADD 49% |
| 43 | TWO SIGMA INVESTMENTS, LP | 312,690312,690 | $7M | 0.25% | ADD 124% |
| 44 | Public Sector Pension Investment Board | 303,316303,316 | $7M | 0.24% | ADD 3% |
| 45 | UBS Group AG | 288,857288,857 | $6M | 0.23% | TRIM -30% |
| 46 | Connor, Clark & Lunn Investment Management Ltd. | 281,681281,681 | $6M | 0.22% | ADD 39% |
| 47 | D. E. Shaw & Co., Inc. | 259,400259,400 | $6M | 0.21% | ADD 203% |
| 48 | Ensign Peak Advisors, Inc | 252,933252,933 | $5M | 0.20% | NEW |
| 49 | RHUMBLINE ADVISERS | 241,492241,492 | $5M | 0.19% | ADD 6% |
| 50 | Susquehanna Portfolio Strategies, LLC | 239,966239,966 | $5M | 0.19% | — |
| 51 | DIADEMA PARTNERS LP | 238,142238,142 | $5M | 0.19% | NEW |
| 52 | Nuveen, LLC | 221,710221,710 | $5M | 0.18% | ADD 57% |
| 53 | TUDOR INVESTMENT CORP ET AL | 216,311216,311 | $5M | 0.17% | ADD 4% |
| 54 | Patient Square Capital LP | 195,000195,000 | $4M | 0.16% | ADD 15% |
| 55 | Schonfeld Strategic Advisors LLC | 193,561193,561 | $4M | 0.15% | ADD 99% |
| 56 | Legal & General Group Plc | 188,650188,650 | $4M | 0.15% | TRIM -8% |
| 57 | Rock Springs Capital Management LP | 180,000180,000 | $4M | 0.14% | — |
| 58 | Swiss National Bank | 171,296171,296 | $4M | 0.14% | — |
| 59 | AMERIPRISE FINANCIAL INC | 160,082160,082 | $3M | 0.13% | TRIM -29% |
| 60 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 158,292158,292 | $3M | 0.13% | ADD 10% |
| 61 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 143,371143,371 | $3M | 0.11% | TRIM -58% |
| 62 | ALLIANCEBERNSTEIN L.P. | 124,085124,085 | $3M | 0.10% | TRIM -7% |
| 63 | Jump Financial, LLC | 135,800135,800 | $3M | 0.11% | NEW |
| 64 | PLATINUM INVESTMENT MANAGEMENT LTD | 134,217134,217 | $3M | 0.11% | — |
| 65 | Point72 Asset Management, L.P. | 129,273129,273 | $3M | 0.10% | TRIM -96% |
| 66 | Rafferty Asset Management, LLC | 115,134115,134 | $2M | 0.09% | ADD 24% |
| 67 | JANE STREET GROUP, LLC | 107,979107,979 | $2M | 0.09% | ADD 132% |
| 68 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 105,776105,776 | $2M | 0.08% | ADD 17% |
| 69 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 89,62589,625 | $2M | 0.07% | TRIM -3% |
| 70 | PRUDENTIAL FINANCIAL INC | 87,97387,973 | $2M | 0.07% | ADD 11% |
| 71 | Parallel Advisors, LLC | 86,55786,557 | $2M | 0.07% | — |
| 72 | Tidal Investments LLC | 86,34286,342 | $2M | 0.07% | NEW |
| 73 | AQR CAPITAL MANAGEMENT LLC | 86,29486,294 | $2M | 0.07% | — |
| 74 | Y-Intercept (Hong Kong) Ltd | 86,19286,192 | $2M | 0.07% | NEW |
| 75 | Knott David M Jr | 81,24181,241 | $2M | 0.06% | TRIM -33% |
| 76 | Man Group plc | 80,86680,866 | $2M | 0.06% | NEW |
| 77 | Russell Investments Group, Ltd. | 80,83380,833 | $2M | 0.06% | TRIM -41% |
| 78 | JPMORGAN CHASE & CO | 80,81780,817 | $2M | 0.06% | ADD 11% |
| 79 | PRICE T ROWE ASSOCIATES INC /MD/ | 75,81675,816 | $2M | 0.06% | ADD 29% |
| 80 | Tema ETFs LLC | 75,21375,213 | $2M | 0.06% | ADD 108% |
| 81 | BARCLAYS PLC | 74,97774,977 | $2M | 0.06% | TRIM -93% |
| 82 | DEUTSCHE BANK AG\ | 73,84773,847 | $2M | 0.06% | ADD 18% |
| 83 | CANADA LIFE ASSURANCE Co | 70,51870,518 | $2M | 0.06% | TRIM -5% |
| 84 | Thrivent Financial for Lutherans | 69,87569,875 | $2M | 0.06% | TRIM -13% |
| 85 | Squarepoint Ops LLC | 66,67466,674 | $1M | 0.05% | NEW |
| 86 | Persistent Asset Partners Ltd | 60,20360,203 | $1M | 0.05% | NEW |
| 87 | STATE OF WISCONSIN INVESTMENT BOARD | 59,19759,197 | $1M | 0.05% | — |
| 88 | VANGUARD ASSET MANAGEMENT, Ltd | 55,90855,908 | $1M | 0.04% | NEW |
| 89 | PROFUND ADVISORS LLC | 54,16354,163 | $1M | 0.04% | ADD 37% |
| 90 | Zurcher Kantonalbank (Zurich Cantonalbank) | 51,02451,024 | $1M | 0.04% | ADD 38% |
| 91 | Burkehill Global Management, LP | 50,00050,000 | $1M | 0.04% | — |
| 92 | SECTORAL ASSET MANAGEMENT INC | 45,07045,070 | $1M | 0.04% | TRIM -21% |
| 93 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 47,51147,511 | $1M | 0.04% | ADD 13% |
| 94 | CANTOR FITZGERALD, L. P. | 45,00045,000 | $972,000 | 0.04% | NEW |
| 95 | MetLife Investment Management, LLC | 44,80944,809 | $967,874 | 0.04% | ADD 3% |
| 96 | JANUS HENDERSON GROUP PLC | 42,33842,338 | $916,406 | 0.03% | — |
| 97 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 42,17042,170 | $910,872 | 0.03% | — |
| 98 | SG Americas Securities, LLC | 42,05542,055 | $908,000 | 0.03% | TRIM -8% |
| 99 | Vanguard Global Advisers, LLC | 41,99641,996 | $907,114 | 0.03% | NEW |
| 100 | State of Alaska, Department of Revenue | 41,86541,865 | $904,000 | 0.03% | TRIM -4% |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| GILEAD SCIENCES, INC. | 30.1M | 31.4M | 31.4M | 31.4M | 31.4M | 31.4M | $679M |
| BlackRock, Inc. | 9.7M | 10.9M | 11.5M | 11.8M | 15.0M | 15.2M | $329M |
| WELLINGTON MANAGEMENT GROUP LLP | — | 1.1M | 936K | 1.3M | 5.2M | 6.1M | $132M |
| STATE STREET CORP | 3.0M | 3.7M | 3.6M | 3.4M | 4.6M | 5.4M | $117M |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 576K | 2.6M | 3.7M | 3.7M | 5.2M | 5.0M | $109M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | — | — | — | — | — | 4.3M | $92M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 3.9M | $83M |
| Woodline Partners LP | 3.5M | 5.1M | 4.0M | 3.8M | 3.8M | 3.8M | $82M |
| MARSHALL WACE, LLP | — | 112K | — | — | 3.4M | 3.8M | $81M |
| Siren, L.L.C. | 1.6M | 1.6M | 1.6M | 2.9M | 3.0M | 3.0M | $65M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.2M | 1.4M | 1.6M | 1.6M | 1.9M | 2.3M | $49M |
| Fisher Asset Management, LLC | — | 138K | 88K | 729K | 1.9M | 2.2M | $47M |
| SAMLYN CAPITAL, LLC | — | — | — | — | 1.6M | 1.9M | $41M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1.5M | 1.6M | 1.4M | 1.4M | 1.7M | 1.7M | $36M |
| DIMENSIONAL FUND ADVISORS LP | 1.7M | 1.7M | 1.7M | 1.5M | 1.5M | 1.4M | $31M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding divides each quarter's as-filed 13F shares by the SEC cover-page share count dated to that same quarter (split-adjusted), not by today's count — so splits and buybacks don't move the line.
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
| Biggest buyers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD PORTFOLIO MANAGEMENT LLC | +4,272,056 | $92M | OPEN |
| VANGUARD CAPITAL MANAGEMENT LLC | +3,856,725 | $83M | OPEN |
| CITADEL ADVISORS LLC | +1,225,234 | $26M | ADD |
| Logos Global Management LP | +1,200,000 | $26M | OPEN |
| WELLINGTON MANAGEMENT GROUP LLP | +905,007 | $20M | ADD |
| Biggest sellers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD GROUP INC | −7,962,874 | $172M | CLOSE |
| Point72 Asset Management, L.P. | −3,150,727 | $68M | TRIM |
| TORONTO DOMINION BANK | −1,484,699 | $32M | CLOSE |
| BARCLAYS PLC | −1,037,281 | $22M | TRIM |
| FRANKLIN RESOURCES INC | −853,491 | $18M | CLOSE |
The 2025-Q4 register is as-filed in ITS OWN share basis; every count below was rebased into the 2026-Q1 basis (no split in between, factor 1). Dollar figures value the SHARE delta at one price — the 2026-03-31 close — rather than differencing two filings' own reported values, which would mix the quarter's price move into the trade figure.
13Fs disclose LONG US-listed positions only — shorts, most derivatives, bonds and non-US listings are invisible here, and a filer's quarter-over-quarter change is not necessarily a trade (index rebalances, in-kind transfers and entity successions all read as flow).
| Quarter | Holders | Shares held | % shares out | Value held |
|---|---|---|---|---|
| 2026-Q1 | 210 | 119,078,229 | 95.0% | $2.6B |
| 2025-Q4 | 208 | 121,446,514 | — | $2.9B |
| 2025-Q3 | 190 | 100,677,127 | 94.6% | $1.4B |
| 2025-Q2 | 186 | 99,802,448 | 94.3% | $812M |
| 2025-Q1 | 187 | 97,252,387 | 91.9% | $764M |
| 2024-Q4 | 186 | 83,922,968 | 91.7% | $1.2B |
| 2024-Q3 | 187 | 53,382,616 | 58.4% | $816M |
| 2024-Q2 | 193 | 52,203,293 | 57.4% | $795M |
| 2024-Q1 | 172 | 54,641,731 | 60.1% | $1.0B |
| 2023-Q4 | 185 | 53,858,491 | 71.9% | $1.0B |
| 2023-Q3 | 187 | 52,891,159 | 71.0% | $949M |
| 2023-Q2 | 181 | 54,703,574 | 74.8% | $1.1B |
| 2023-Q1 | 179 | 58,906,712 | 80.7% | $1.1B |
| 2022-Q4 | 199 | 53,779,638 | 74.3% | $1.1B |
| 2022-Q3 | 184 | 52,635,330 | 72.9% | $1.4B |
| 2022-Q2 | 173 | 52,636,765 | 73.4% | $1.3B |
| 2022-Q1 | 157 | 50,792,220 | 71.5% | $1.6B |
| 2021-Q4 | 142 | 50,943,583 | 72.5% | $2.1B |
| 2021-Q3 | 131 | 48,272,090 | 67.6% | $1.7B |
| 2021-Q2 | 130 | 45,167,252 | 63.6% | $1.2B |
| 2021-Q1 | 148 | 44,736,529 | 63.1% | $1.3B |
| 2020-Q4 | 148 | 44,674,440 | 68.8% | $1.2B |
| 2020-Q3 | 128 | 44,389,594 | 68.4% | $761M |
| 2020-Q2 | 139 | 41,841,089 | 90.9% | $1.0B |
| 2020-Q1 | 92 | 26,997,645 | 58.7% | $375M |
| 2019-Q4 | 75 | 27,496,653 | 60.0% | $278M |
| 2019-Q3 | 75 | 25,809,955 | 56.3% | $235M |
| 2019-Q2 | 78 | 26,456,210 | 59.4% | $210M |
| 2019-Q1 | 64 | 25,799,373 | 57.9% | $322M |
| 2018-Q4 | 67 | 27,100,341 | 61.0% | $292M |
| 2018-Q3 | 57 | 22,486,491 | 50.6% | $313M |
| 2018-Q2 | 64 | 22,402,208 | 50.4% | $274M |
| 2018-Q1 | 57 | 19,855,682 | 44.7% | $293M |
Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).
