NAUT US Equity

Nautilus Biotechnology, Inc.

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Health Care · Laboratory Analytical Instruments · CIK 1808805 · FYE 1231

$1.03

-0.01 (-0.96%)

USD · as of 2026-07-30 · marketstack

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Institutional ownership· 13F filers holding NAUT · 2026-Q1 methodology → sources →

81 holders

% of shares outstanding held

42.9%

Shares held (13F)

54,340,710

Reporting holders

Active share of register92.1%73 active filers

Index / screened out7.9%8 filers

Reporting holders812026-Q1

Top-10 concentration89.7%

HHI0.1846

Effective holders5.4

Crowding percentile35.7of 800 same-size names

Top holders

largest 81 of 81 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	a16z Capital Management, L.L.C.	17,653,91717.7M	$68M	13.95%	—
2	PERCEPTIVE ADVISORS LLC	12,594,21112.6M	$49M	9.95%	—
3	Cercano Management LLC	7,172,9857.2M	$28M	5.67%	—
4	VANGUARD CAPITAL MANAGEMENT LLC	2,545,5972.5M	$10M	2.01%	NEW†
5	Clearstead Advisors, LLC	2,329,7842.3M	$9M	1.84%	NEW
6	Comprehensive Financial Management LLC	2,207,6192.2M	$9M	1.74%	—
7	AMAZON COM INC	1,457,0551.5M	$6M	1.15%	—
8	MILLENNIUM MANAGEMENT LLC	1,273,3831.3M	$5M	1.01%	ADD 25%
9	SENTINEL TRUST CO LBA	750,000750,000	$3M	0.59%	—
10	ACADIAN ASSET MANAGEMENT LLC	741,246741,246	$3M	0.59%	ADD 21%
11	Tikvah Management LLC	726,895726,895	$3M	0.57%	—
12	GEODE CAPITAL MANAGEMENT, LLC	603,524603,524	$2M	0.48%	ADD 8%
13	GOLDMAN SACHS GROUP INC	390,768390,768	$2M	0.31%	ADD 31%
14	DIMENSIONAL FUND ADVISORS LP	329,123329,123	$1M	0.26%	ADD 15%
15	MARSHALL WACE, LLP	319,882319,882	$1M	0.25%	ADD 173%
16	VANGUARD FIDUCIARY TRUST CO	305,526305,526	$1M	0.24%	NEW
17	RENAISSANCE TECHNOLOGIES LLC	265,700265,700	$1M	0.21%	ADD 2%
18	STATE STREET CORP	216,270216,270	$839,128	0.17%	ADD 7%
19	HILLMAN CO	200,000200,000	$776,000	0.16%	—
20	BlackRock, Inc.	187,671187,671	$728,163	0.15%	—
21	Crewe Advisors LLC	136,052136,052	$527,882	0.11%	—
22	BRIDGEWAY CAPITAL MANAGEMENT, LLC	130,000130,000	$504,400	0.10%	—
23	Corient Private Wealth LLC	114,788114,788	$445,377	0.09%	TRIM -50%
24	NORTHERN TRUST CORP	107,011107,011	$415,203	0.08%	—
25	CROWN ADVISORS MANAGEMENT, INC.	100,000100,000	$388,000	0.08%	NEW
26	Point72 Asset Management, L.P.	83,04383,043	$322,207	0.07%	ADD 37%
27	Qube Research & Technologies Ltd	79,62379,623	$308,937	0.06%	TRIM -35%
28	BARCLAYS PLC	73,32573,325	$284,501	0.06%	ADD 52%
29	Palumbo Wealth Management LLC	65,23165,231	$253,097	0.05%	ADD 59%
30	HRT FINANCIAL LP	65,25465,254	$253,000	0.05%	NEW
31	BANK OF AMERICA CORP /DE/	63,14763,147	$245,010	0.05%	ADD 213%
32	JANE STREET GROUP, LLC	61,80261,802	$239,792	0.05%	TRIM -70%
33	Brevan Howard Capital Management LP	60,50160,501	$234,744	0.05%	NEW
34	GSA CAPITAL PARTNERS LLP	54,69954,699	$212,000	0.04%	TRIM -56%
35	CITIZENS FINANCIAL GROUP INC/RI	50,00050,000	$194,000	0.04%	NEW
36	MORGAN STANLEY	49,50349,503	$192,072	0.04%	ADD 28%
37	HSBC HOLDINGS PLC	49,44949,449	$189,884	0.04%	TRIM -50%
38	JACOBS LEVY EQUITY MANAGEMENT, INC	46,39446,394	$180,009	0.04%	NEW
39	Catalyst Funds Management Pty Ltd	46,32846,328	$179,753	0.04%	NEW
40	Fayez Sarofim & Co	45,00045,000	$174,600	0.04%	—
41	Ashton Thomas Private Wealth, LLC	45,00045,000	$174,600	0.04%	—
42	Caprock Group, LLC	44,09044,090	$171,069	0.03%	—
43	POLEN CAPITAL MANAGEMENT LLCtracked	40,34540,345	$156,539	0.03%	NEW
44	SEI INVESTMENTS CO	38,64338,643	$149,935	0.03%	NEW
45	Presidio Capital Management, LLC	34,66434,664	$134,496	0.03%	—
46	CAPTRUST FINANCIAL ADVISORS	34,00334,003	$131,932	0.03%	—
47	Badgley Phelps Wealth Managers, LLC	30,00030,000	$116,400	0.02%	—
48	Hudson Bay Capital Management LP	29,59429,594	$114,825	0.02%	ADD 55%
49	UBS Group AG	26,90326,903	$104,384	0.02%	ADD 421%
50	Callan Family Office, LLC	25,97025,970	$100,764	0.02%	—
51	OMERS ADMINISTRATION Corp	24,50024,500	$95,060	0.02%	TRIM -77%
52	Diametric Capital, LP	22,80622,806	$88,487	0.02%	NEW
53	CITIGROUP INC	21,14221,142	$82,031	0.02%	TRIM -66%
54	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	19,30019,300	$74,884	0.02%	NEW
55	Vanguard Global Advisers, LLC	16,60716,607	$64,435	0.01%	NEW
56	BLAIR WILLIAM & CO/IL	15,00015,000	$58,200	0.01%	NEW
57	FNY Investment Advisers, LLC	14,00014,000	$54,000	0.01%	—
58	Engineers Gate Manager LP	13,87813,878	$53,847	0.01%	NEW
59	BNP PARIBAS FINANCIAL MARKETS	13,37213,372	$51,883	0.01%	TRIM -52%
60	Vanguard Capital Wealth Advisors	13,00013,000	$50,440	0.01%	—
61	CTC Alternative Strategies, Ltd.	12,39712,397	$48,100	0.01%	NEW
62	Schonfeld Strategic Advisors LLC	12,01012,010	$46,598	0.01%	NEW
63	Garde Capital, Inc.	11,00011,000	$42,680	0.01%	TRIM -39%
64	NINE MASTS CAPITAL Ltd	10,39510,395	$40,333	0.01%	NEW
65	BFSG, LLC	6,7006,700	$25,996	0.01%	NEW
66	Rockefeller Capital Management L.P.	6,2006,200	$24,056	0.00%	ADD 24%
67	FMR LLC	3,3433,343	$12,971	0.00%	TRIM -4%
68	Federation des caisses Desjardins du Quebec	1,0001,000	$3,880	0.00%	NEW
69	TD Waterhouse Canada Inc.	1,0001,000	$3,350	0.00%	—
70	NATIONAL BANK OF CANADA /FI/	300300	$1,164	0.00%	NEW
71	OSAIC HOLDINGS, INC.	295295	$1,144	0.00%	TRIM -59%
72	WELLS FARGO & COMPANY/MN	260260	$1,009	0.00%	TRIM -54%
73	GILL CAPITAL PARTNERS, LLC	250250	$970	0.00%	NEW
74	Your Advocates Ltd., LLP	150150	$582	0.00%	—
75	SBI Securities Co., Ltd.	100100	$388	0.00%	NEW
76	Optiver Holding B.V.	4040	$155	0.00%	—
77	CWM, LLC	2929	$113	0.00%	TRIM -47%
78	EverSource Wealth Advisors, LLC	1818	$70	0.00%	TRIM -63%
79	Caitong International Asset Management Co., Ltd	11	$4	0.00%	NEW
80	ROYAL BANK OF CANADA	9191	$0	0.00%	TRIM -97%
81	Covestor Ltd	88	$0	0.00%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Buyers & sellers2026-Q1 vs 2025-Q4 · 41 bought / 29 sold · net −4,120,207 shares · 3.7d of ADV

Bought41 filers

Shares: 6,703,783
Value: $26M
Opened: 25 · 5,759,116 sh
Days of ADV: 6.0d

Sold29 filers

Shares: 10,823,990
Value: $42M
Closed: 12 · 10,253,803 sh
Days of ADV: 9.7d

Net (all filers) −4,120,207 sh · $16M · −7.0% of the prior register

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

a16z Capital Management, L.L.C.

17.7M

$68M

PERCEPTIVE ADVISORS LLC

12.6M

$49M

Cercano Management LLC

7.2M

$28M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.5M

$10M

Clearstead Advisors, LLC

—

2.3M

$9M

Comprehensive Financial Management LLC

2.2M

$9M

AMAZON COM INC

1.5M

$6M

MILLENNIUM MANAGEMENT LLC

38K

90K

1.1M

968K

1.0M

1.3M

$5M

SENTINEL TRUST CO LBA

255K

280K

—

750K

$3M

ACADIAN ASSET MANAGEMENT LLC

11K

62K

69K

243K

612K

741K

$3M

Tikvah Management LLC

727K

$3M

GEODE CAPITAL MANAGEMENT, LLC

1.1M

1.2M

554K

561K

604K

$2M

GOLDMAN SACHS GROUP INC

196K

172K

315K

118K

297K

391K

$2M

DIMENSIONAL FUND ADVISORS LP

770K

660K

551K

365K

285K

329K

$1M

MARSHALL WACE, LLP

—

117K

320K

$1M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding divides each quarter's as-filed 13F shares by the SEC cover-page share count dated to that same quarter (split-adjusted), not by today's count — so splits and buybacks don't move the line.

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	81	54,340,710	42.9%	$211M
2025-Q4	68	58,460,917

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

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13F

Institutional ownership· 13F filers holding NAUT · 2026-Q1 methodology → sources →

81 holders

% of shares outstanding held

42.9%

Shares held (13F)

54,340,710

Reporting holders

Active share of register92.1%73 active filers

Index / screened out7.9%8 filers

Reporting holders812026-Q1

Top-10 concentration89.7%

HHI0.1846

Effective holders5.4

Crowding percentile35.7of 800 same-size names

Top holders

largest 81 of 81 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	a16z Capital Management, L.L.C.	17,653,91717.7M	$68M	13.95%	—
2	PERCEPTIVE ADVISORS LLC	12,594,21112.6M	$49M	9.95%	—
3	Cercano Management LLC	7,172,9857.2M	$28M	5.67%	—
4	VANGUARD CAPITAL MANAGEMENT LLC	2,545,5972.5M	$10M	2.01%	NEW†
5	Clearstead Advisors, LLC	2,329,7842.3M	$9M	1.84%	NEW
6	Comprehensive Financial Management LLC	2,207,6192.2M	$9M	1.74%	—
7	AMAZON COM INC	1,457,0551.5M	$6M	1.15%	—
8	MILLENNIUM MANAGEMENT LLC	1,273,3831.3M	$5M	1.01%	ADD 25%
9	SENTINEL TRUST CO LBA	750,000750,000	$3M	0.59%	—
10	ACADIAN ASSET MANAGEMENT LLC	741,246741,246	$3M	0.59%	ADD 21%
11	Tikvah Management LLC	726,895726,895	$3M	0.57%	—
12	GEODE CAPITAL MANAGEMENT, LLC	603,524603,524	$2M	0.48%	ADD 8%
13	GOLDMAN SACHS GROUP INC	390,768390,768	$2M	0.31%	ADD 31%
14	DIMENSIONAL FUND ADVISORS LP	329,123329,123	$1M	0.26%	ADD 15%
15	MARSHALL WACE, LLP	319,882319,882	$1M	0.25%	ADD 173%
16	VANGUARD FIDUCIARY TRUST CO	305,526305,526	$1M	0.24%	NEW
17	RENAISSANCE TECHNOLOGIES LLC	265,700265,700	$1M	0.21%	ADD 2%
18	STATE STREET CORP	216,270216,270	$839,128	0.17%	ADD 7%
19	HILLMAN CO	200,000200,000	$776,000	0.16%	—
20	BlackRock, Inc.	187,671187,671	$728,163	0.15%	—
21	Crewe Advisors LLC	136,052136,052	$527,882	0.11%	—
22	BRIDGEWAY CAPITAL MANAGEMENT, LLC	130,000130,000	$504,400	0.10%	—
23	Corient Private Wealth LLC	114,788114,788	$445,377	0.09%	TRIM -50%
24	NORTHERN TRUST CORP	107,011107,011	$415,203	0.08%	—
25	CROWN ADVISORS MANAGEMENT, INC.	100,000100,000	$388,000	0.08%	NEW
26	Point72 Asset Management, L.P.	83,04383,043	$322,207	0.07%	ADD 37%
27	Qube Research & Technologies Ltd	79,62379,623	$308,937	0.06%	TRIM -35%
28	BARCLAYS PLC	73,32573,325	$284,501	0.06%	ADD 52%
29	Palumbo Wealth Management LLC	65,23165,231	$253,097	0.05%	ADD 59%
30	HRT FINANCIAL LP	65,25465,254	$253,000	0.05%	NEW
31	BANK OF AMERICA CORP /DE/	63,14763,147	$245,010	0.05%	ADD 213%
32	JANE STREET GROUP, LLC	61,80261,802	$239,792	0.05%	TRIM -70%
33	Brevan Howard Capital Management LP	60,50160,501	$234,744	0.05%	NEW
34	GSA CAPITAL PARTNERS LLP	54,69954,699	$212,000	0.04%	TRIM -56%
35	CITIZENS FINANCIAL GROUP INC/RI	50,00050,000	$194,000	0.04%	NEW
36	MORGAN STANLEY	49,50349,503	$192,072	0.04%	ADD 28%
37	HSBC HOLDINGS PLC	49,44949,449	$189,884	0.04%	TRIM -50%
38	JACOBS LEVY EQUITY MANAGEMENT, INC	46,39446,394	$180,009	0.04%	NEW
39	Catalyst Funds Management Pty Ltd	46,32846,328	$179,753	0.04%	NEW
40	Fayez Sarofim & Co	45,00045,000	$174,600	0.04%	—
41	Ashton Thomas Private Wealth, LLC	45,00045,000	$174,600	0.04%	—
42	Caprock Group, LLC	44,09044,090	$171,069	0.03%	—
43	POLEN CAPITAL MANAGEMENT LLCtracked	40,34540,345	$156,539	0.03%	NEW
44	SEI INVESTMENTS CO	38,64338,643	$149,935	0.03%	NEW
45	Presidio Capital Management, LLC	34,66434,664	$134,496	0.03%	—
46	CAPTRUST FINANCIAL ADVISORS	34,00334,003	$131,932	0.03%	—
47	Badgley Phelps Wealth Managers, LLC	30,00030,000	$116,400	0.02%	—
48	Hudson Bay Capital Management LP	29,59429,594	$114,825	0.02%	ADD 55%
49	UBS Group AG	26,90326,903	$104,384	0.02%	ADD 421%
50	Callan Family Office, LLC	25,97025,970	$100,764	0.02%	—
51	OMERS ADMINISTRATION Corp	24,50024,500	$95,060	0.02%	TRIM -77%
52	Diametric Capital, LP	22,80622,806	$88,487	0.02%	NEW
53	CITIGROUP INC	21,14221,142	$82,031	0.02%	TRIM -66%
54	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	19,30019,300	$74,884	0.02%	NEW
55	Vanguard Global Advisers, LLC	16,60716,607	$64,435	0.01%	NEW
56	BLAIR WILLIAM & CO/IL	15,00015,000	$58,200	0.01%	NEW
57	FNY Investment Advisers, LLC	14,00014,000	$54,000	0.01%	—
58	Engineers Gate Manager LP	13,87813,878	$53,847	0.01%	NEW
59	BNP PARIBAS FINANCIAL MARKETS	13,37213,372	$51,883	0.01%	TRIM -52%
60	Vanguard Capital Wealth Advisors	13,00013,000	$50,440	0.01%	—
61	CTC Alternative Strategies, Ltd.	12,39712,397	$48,100	0.01%	NEW
62	Schonfeld Strategic Advisors LLC	12,01012,010	$46,598	0.01%	NEW
63	Garde Capital, Inc.	11,00011,000	$42,680	0.01%	TRIM -39%
64	NINE MASTS CAPITAL Ltd	10,39510,395	$40,333	0.01%	NEW
65	BFSG, LLC	6,7006,700	$25,996	0.01%	NEW
66	Rockefeller Capital Management L.P.	6,2006,200	$24,056	0.00%	ADD 24%
67	FMR LLC	3,3433,343	$12,971	0.00%	TRIM -4%
68	Federation des caisses Desjardins du Quebec	1,0001,000	$3,880	0.00%	NEW
69	TD Waterhouse Canada Inc.	1,0001,000	$3,350	0.00%	—
70	NATIONAL BANK OF CANADA /FI/	300300	$1,164	0.00%	NEW
71	OSAIC HOLDINGS, INC.	295295	$1,144	0.00%	TRIM -59%
72	WELLS FARGO & COMPANY/MN	260260	$1,009	0.00%	TRIM -54%
73	GILL CAPITAL PARTNERS, LLC	250250	$970	0.00%	NEW
74	Your Advocates Ltd., LLP	150150	$582	0.00%	—
75	SBI Securities Co., Ltd.	100100	$388	0.00%	NEW
76	Optiver Holding B.V.	4040	$155	0.00%	—
77	CWM, LLC	2929	$113	0.00%	TRIM -47%
78	EverSource Wealth Advisors, LLC	1818	$70	0.00%	TRIM -63%
79	Caitong International Asset Management Co., Ltd	11	$4	0.00%	NEW
80	ROYAL BANK OF CANADA	9191	$0	0.00%	TRIM -97%
81	Covestor Ltd	88	$0	0.00%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Buyers & sellers2026-Q1 vs 2025-Q4 · 41 bought / 29 sold · net −4,120,207 shares · 3.7d of ADV

Bought41 filers

Shares: 6,703,783
Value: $26M
Opened: 25 · 5,759,116 sh
Days of ADV: 6.0d

Sold29 filers

Shares: 10,823,990
Value: $42M
Closed: 12 · 10,253,803 sh
Days of ADV: 9.7d

Net (all filers) −4,120,207 sh · $16M · −7.0% of the prior register

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

a16z Capital Management, L.L.C.

17.7M

$68M

PERCEPTIVE ADVISORS LLC

12.6M

$49M

Cercano Management LLC

7.2M

$28M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.5M

$10M

Clearstead Advisors, LLC

—

2.3M

$9M

Comprehensive Financial Management LLC

2.2M

$9M

AMAZON COM INC

1.5M

$6M

MILLENNIUM MANAGEMENT LLC

38K

90K

1.1M

968K

1.0M

1.3M

$5M

SENTINEL TRUST CO LBA

255K

280K

—

750K

$3M

ACADIAN ASSET MANAGEMENT LLC

11K

62K

69K

243K

612K

741K

$3M

Tikvah Management LLC

727K

$3M

GEODE CAPITAL MANAGEMENT, LLC

1.1M

1.2M

554K

561K

604K

$2M

GOLDMAN SACHS GROUP INC

196K

172K

315K

118K

297K

391K

$2M

DIMENSIONAL FUND ADVISORS LP

770K

660K

551K

365K

285K

329K

$1M

MARSHALL WACE, LLP

—

117K

320K

$1M

Institutional footprint by quarter

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	81	54,340,710	42.9%	$211M
2025-Q4	68	58,460,917

Short interest has its own tab now — open SI →

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13F

NAUT US Equity☆

Institutional ownership· 13F filers holding NAUT · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

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Institutional ownership· 13F filers holding NAUT · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

▸Register gapwho owns your peers and not you

NAUT US Equity