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Clinical trials
catalyst calendar across sponsors →Studies where MMM is the lead sponsor, as filed with ClinicalTrials.gov. Completion dates are the sponsor's own projected windows and are revised as a study runs. Active studies first, then completed and stopped — newest readout first within each.
7 interventional · 5 observational · 6 with posted results
Held by 22 tracked-famous managers (D. E. Shaw & Co., Inc., Holocene Advisors, LP, Balyasny Asset Management L.P., Qube Research & Technologies Ltd, CITADEL ADVISORS LLC, +17 more) · FINRA short interest 2.1 days to cover (settled 2026-07-31) · government filings 180d: 2 congress / 2 executive
| Study | Phase | Status | Interventions | Conditions | Enrollment | Primary completion | Updated |
|---|---|---|---|---|---|---|---|
| EXD-959 Orthodontic Brackets and EXD-961 Related Instruments TrialNCT03606551observationalPerformance and functionality of the EXD-959 Bracket System and Related EXD-961 instruments in correcting dental malocclusions. | — | Unknown status | Device: EXD-959 Bracket System | Malocclusion | 78 | 2021-12-30 | 2021-02-21 |
| Evaluation of V.A.C. VERAFLO CLEANSE CHOICE™ Dressing Using Normal Saline to Promote Increased Healthy Wound Bed TissueNCT04026334Percent change in wound bed surface area (cm2) of clean, healthy, viable tissueOpen-label · Treatment | Not applicable | Terminatedsponsor's stated reason: Insufficient subject accrual rate | Device: V.A.C. VERAFLO CLEANSE CHOICE™ dressing with Normal Saline | Wound, Wound Heal, Wounds and Injuries, Granulation Tissue, Negative-pressure Wound Therapy | 8 | 2020-08-28actual | 2022-08-01 |
| Clinical Study of Filtek™ Bulk Fill Posterior Restorative in Class I and II RestorationsNCT03764059results2023-07-21Clinical Acceptance Rate of Restoration at 1 Year After ReplacementRandomized · Double-masked · TreatmentStudy Protocol ↗ · Statistical Analysis Plan ↗ | Not applicable | Completed | Device: Filtek™ Bulk Fill Posterior Restorative, Filtek™ Z350XT Universal Restorative | Dental Caries Class I, Dental Caries Class II | 240 | 2019-11-14actual | 2023-07-21 |
| A Clinical Study to Assess a Compression Device in Patients With Venous Leg UlcersNCT02561013The primary efficacy endpoint is the number of ulcers achieving complete closure (100% epithelialization) after 12 weeksRandomized · Open-label · Treatment | Not applicable | Withdrawnsponsor's stated reason: Business reasons | Device: 3M™ Coban™ Custom Fit Compression System, Profore | Varicose Ulcer | 0 | Mar 2016 | 2015-11-25 |
| In Vivo Efficacy Study of Patient Preoperative PrepsNCT02203591results2020-11-23Responder RateRandomized · Single-masked · Prevention | Phase 3 | Completed | Drug: 3M CHG/IPA Prep C, 3M CHG/IPA Prep CH, ChloraPrep, Normal Saline | Bacterial Reduction Post-product Application | 738 | Mar 2015actual | 2020-11-23 |
| Clinical Evaluation of the SNaP Wound Care SystemNCT01113658Frequency of complaints about device use and operationOpen-label · Treatment | Not applicable | Withdrawnsponsor's stated reason: The study was terminated by Spiracur (original sponsor). Efforts were made to contact the PI/study team members, but were unsuccessful. | Device: SNaP Wound Care System | Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers, Venous Stasis Ulcers | 0 | Apr 2014 | 2022-08-01 |
| Zero Heat Flux Thermometry System Comparison TrialNCT01670760results2020-08-21Body Temperature Difference in Degrees CelsiusOpen-label · Basic science | Not applicable | Completed | Device: Zero-heat-flux thermometry | Body Temperature, Thermosensing, Temperature | 20 | Jun 2013actual | 2020-09-22 |
| Post-Market Clinical Evaluation of the Spiracur SNaP Wound Care System for Treatment of Acute Trauma and Acute Surgical Excision WoundsNCT01417234results2020-11-06observationalWound Closure | — | Completed | Device: SNaP® Wound Care System | Trauma-related Wound, Surgical Wound, Recent | 30 | Oct 2012actual | 2022-08-01 |
| Impact of Pre-surgical Nasal Bacterial Reduction on Postoperative Surgical Site Infections / Standard Care ChangeNCT01148030observationalSurgical Site Infection | — | Terminatedsponsor's stated reason: Outcome measures for pre-intervention were much lower than anticipated. | Drug: 3M Skin and Nasal Antiseptic | Surgical Site Infection | 333 | Jul 2012actual | 2014-03-03 |
| Comparison Study of Core Temperature Thermometry SystemsNCT01255865results2020-08-25observationalTemperature Agreement in Degrees Celsius. | — | Completed | — | Thermometry Device Comparisons | 111 | Aug 2011actual | 2020-08-25 |
| SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic WoundsNCT00951080results2020-10-19Percent Change in Wound AreaRandomized · Open-label · Treatment | Not applicable | Completed | Device: Traditional NPWT System, SNaP Wound Care System | Ulcers, Wounds | 132 | Mar 2011actual | 2022-08-01 |
| Human Tissue Repository for Wound CareNCT01432054observationalThe study design is a collection of human biological specimens in Subjects with various wound classifications and types for the purpose of a Human Tissue Repository to be used as a resource for future tissue repair research at KCI USA, Inc | — | Withdrawnsponsor's stated reason: business decision | — | Human Tissue Repository | 0 | — | 2022-08-01 |
Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.
Source: ClinicalTrials.gov, retrieved 2026-08-19