Clinical trials
catalyst calendar across sponsors →Studies where MED is the lead sponsor, as filed with ClinicalTrials.gov. Completion dates are the sponsor's own projected windows and are revised as a study runs. Active studies first, then completed and stopped — newest readout first within each.
3 interventional · 3 observational · 2 with posted results
Held by 12 tracked-famous managers (RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, MARSHALL WACE, LLP, AQR CAPITAL MANAGEMENT LLC, JANE STREET GROUP, LLC, +7 more) · FINRA short interest 9.2 days to cover (settled 2026-07-31) · government filings 180d: none disclosed
| Study | Phase | Status | Interventions | Conditions | Enrollment | Primary completion | Updated |
|---|---|---|---|---|---|---|---|
| Weight Loss Using the Take Shape For Life Program or the Medifast Direct Program Versus a Self-Directed DietNCT02835092results2019-01-07Body Weight ChangeRandomized · Open-label · TreatmentStatistical Analysis Plan ↗ · Study Protocol ↗ | Not applicable | Completed | Other: Take Shape For Life Program, Medifast Direct Program, Self-directed Control | Overweight, Obesity | 198 | Feb 2017actual | 2019-01-22 |
| SUCCESS Tracking StudyNCT01021917observationalTo compare change in body weight among subjects in Medifast Direct, Take Shape For Life, and Other Dieters. | — | Terminatedsponsor's stated reason: Given the length of time data was collected (i.e. 5 1/3 years), we do not anticipate a change any potential conclusions by completing the final survey. | — | Obesity | 332 | Jul 2014actual | 2017-08-29 |
| Retrospective Chart Review of the 5 & 2 & 2 and 4 & 2 & 1 PlansNCT02150837results2019-09-13observationalBody Weight | — | Completed | Other: 5 & 2 & 2 Plan, 4 & 2 & 1 Plan | Obesity | 372 | May 2014actual | 2019-09-13 |
| A Retrospective Chart Review of Three Medifast Weight Control CentersNCT01662830observationalChanges in weight | — | Completed | — | Obesity | 446 | Mar 2012actual | 2012-08-10 |
| Comparison of Medifast's 5 & 1 Plan to a Food-based Plan of Equal CaloriesNCT01011491Weight change (in kilograms) from week 0Randomized · Open-label · Treatment | Not applicable | Completed | Other: Medifast 5 & 1 Plan for weight loss and weight maintenance, Food-based diet plan for weight loss and weight maintenance | Obesity | 90 | Sep 2009actual | 2009-11-11 |
| Evaluation of Metabolism-Boosting BeveragesNCT01029236To assess the effect of MBBs on REE by performing indirect calorimetryOpen-label · Basic science | Not applicable | Completed | Other: Medifast Metabolism-boosting Beverages | Energy Expenditure, Appetite | 30 | Dec 2007actual | 2009-12-09 |
Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.
Source: ClinicalTrials.gov, retrieved 2026-08-19