Innoviva, Inc. (Nasdaq: INVA), an SEC filer in Pharmaceutical Preparations, closed at $20.97, +0.0%, on 2026-08-28, with a market cap of $1.5B as of 2026-08-27, a trailing P/E of 6.4, a return on equity of 29.1%, a net margin of 65.9% and 3-year sales growth of 7.5%. Institutional ownership, earnings history and filed financials are on the tabs below.
Institutional 13F holdings sum to 102.0% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them.
| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 11,307,84511.3M | $263M | 15.27% | ADD 6% |
| 2 | DIMENSIONAL FUND ADVISORS LP | 4,436,4274.4M | $103M | 5.99% | — |
| 3 | VANGUARD PORTFOLIO MANAGEMENT LLC | 4,224,9514.2M | $98M | 5.70% | NEW† |
| 4 | RENAISSANCE TECHNOLOGIES LLC | 4,055,6324.1M | $94M | 5.48% | TRIM -4% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 3,141,5813.1M | $73M | 4.24% | NEW† |
| 6 | STATE STREET CORP | 3,060,3773.1M | $71M | 4.13% | ADD 9% |
| 7 | MILLENNIUM MANAGEMENT LLC | 2,279,4512.3M | $53M | 3.08% | ADD 42% |
| 8 | Sarissa Capital Management LP | 2,130,9502.1M | $50M | 2.88% | TRIM -24% |
| 9 | SYSTEMATIC FINANCIAL MANAGEMENT LP | 2,024,0822.0M | $47M | 2.73% | TRIM -4% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 1,929,7181.9M | $45M | 2.61% | ADD 10% |
† NEW this big is usually a rename.
Ranked by each filer’s own reported value, not shares.
1 holder — The filer reported no value for this line, so it carries no dollar figure and is left out of the percentage and value columns.
| Biggest buyers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD PORTFOLIO MANAGEMENT LLC | +4,224,951 | $98M | OPEN |
| VANGUARD CAPITAL MANAGEMENT LLC | +3,141,581 | $73M | OPEN |
| MILLENNIUM MANAGEMENT LLC | +669,146 | $16M | ADD |
| TWO SIGMA INVESTMENTS, LP | +644,399 | $15M | ADD |
| BlackRock, Inc. | +631,070 | $15M | ADD |
| Biggest sellers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD GROUP INC | −7,917,103 | $184M | CLOSE |
| FRANKLIN RESOURCES INC | −1,134,734 | $26M | TRIM |
| Sarissa Capital Management LP | −685,072 | $16M | TRIM |
| HSBC HOLDINGS PLC | −545,684 | $13M | TRIM |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | −470,165 | $11M | TRIM |
Prior quarter split-rebased · 13Fs are long, US-listed only.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 9.5M | 9.2M | 9.1M | 9.4M | 10.7M | 11.3M | $263M |
| DIMENSIONAL FUND ADVISORS LP | 4.9M | 4.7M | 4.3M | 4.3M | 4.4M | 4.4M | $103M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | — | — | — | — | — | 4.2M | $98M |
| RENAISSANCE TECHNOLOGIES LLC | 4.3M | 4.6M | 4.8M | 4.6M | 4.2M | 4.1M | $94M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 3.1M | $73M |
| STATE STREET CORP | 2.5M | 2.4M | 2.5M | 2.6M | 2.8M | 3.1M | $71M |
| MILLENNIUM MANAGEMENT LLC | 401K | 1.7M | 2.0M | 1.6M | 1.6M | 2.3M | $53M |
| Sarissa Capital Management LP | 7.3M | 2.8M | 2.8M | 2.8M | 2.8M | 2.1M | $50M |
| SYSTEMATIC FINANCIAL MANAGEMENT LP | 2.0M | 2.1M | 2.1M | 2.1M | 2.1M | 2.0M | $47M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.4M | 1.4M | 1.5M | 1.6M | 1.8M | 1.9M | $45M |
Green = added, red = trimmed, grey = held; a dash is a quarter with no 13F on file — a gap, not an exit.
Breaks = no 13F that quarter.
Short interest has its own tab now — open SI →
SEC Form 13F · ~10,250 filers, 10y · long-only, US-listed, filed ≤45d after quarter-end.
SEC Schedule 13D/G XML · group aggregate.
