INVA US Equity

Innoviva, Inc.

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Health Care · Pharmaceutical Preparations · CIK 1080014 · FYE 1231

$21.81

+0.51 (+2.39%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding INVA · 2026-Q1 methodology → sources →

284 holders

% of shares outstanding held

101.8%

Shares held (13F)

75,135,931

Reporting holders

284

Institutional 13F holdings sum to 101.8% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 6,282,273 shares (settlement 2026-04-30) accounts for the excess.

Top holders

largest 100 of 284 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	11,307,84511.3M	$263M	15.32%	ADD 6%
2	DIMENSIONAL FUND ADVISORS LP	4,436,4274.4M	$103M	6.01%	—
3	VANGUARD PORTFOLIO MANAGEMENT LLC	4,224,9514.2M	$98M	5.72%	NEW†
4	RENAISSANCE TECHNOLOGIES LLC	4,055,6324.1M	$94M	5.49%	TRIM -4%
5	VANGUARD CAPITAL MANAGEMENT LLC	3,141,5813.1M	$73M	4.26%	NEW†
6	STATE STREET CORP	3,060,3773.1M	$71M	4.15%	ADD 9%
7	MILLENNIUM MANAGEMENT LLC	2,279,4512.3M	$53M	3.09%	ADD 42%
8	Sarissa Capital Management LP	2,130,9502.1M	$50M	2.89%	TRIM -24%
9	SYSTEMATIC FINANCIAL MANAGEMENT LP	2,024,0822.0M	$47M	2.74%	TRIM -4%
10	GEODE CAPITAL MANAGEMENT, LLC	1,929,7181.9M	$45M	2.61%	ADD 10%
11	AMERICAN CENTURY COMPANIES INC	1,910,0211.9M	$45M	2.59%	TRIM -15%
12	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	1,887,5701.9M	$44M	2.56%	TRIM -20%
13	Boston Partners	1,718,8671.7M	$40M	2.33%	ADD 11%
14	BANK OF AMERICA CORP /DE/	1,619,9941.6M	$38M	2.19%	ADD 7%
15	GOLDMAN SACHS GROUP INC	1,593,3831.6M	$37M	2.16%	ADD 42%
16	MARSHALL WACE, LLP	1,504,4111.5M	$35M	2.04%	ADD 8%
17	TWO SIGMA INVESTMENTS, LP	1,484,2641.5M	$35M	2.01%	ADD 77%
18	MORGAN STANLEY	1,310,7501.3M	$31M	1.78%	TRIM -8%
19	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,163,7131.2M	$27M	1.58%	ADD 14%
20	ROYCE & ASSOCIATES LP	1,061,4481.1M	$25M	1.44%	ADD 15%
21	DEUTSCHE BANK AG\	908,067908,067	$21M	1.23%	ADD 7%
22	Invesco Ltd.	904,282904,282	$21M	1.23%	ADD 9%
23	DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	892,336892,336	$21M	1.21%	ADD 28%
24	Qube Research & Technologies Ltd	786,107786,107	$18M	1.07%	TRIM -35%
25	NORTHERN TRUST CORP	774,303774,303	$18M	1.05%	ADD 11%
26	Man Group plc	744,791744,791	$17M	1.01%	TRIM -12%
27	Nuveen, LLC	620,482620,482	$14M	0.84%	TRIM -4%
28	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	574,825574,825	$13M	0.78%	NEW
29	VICTORY CAPITAL MANAGEMENT INC	523,415523,415	$12M	0.71%	ADD 42%
30	Allianz Asset Management GmbH	519,017519,017	$12M	0.70%	ADD 54%
31	AQR CAPITAL MANAGEMENT LLC	495,841495,841	$12M	0.67%	ADD 34%
32	VANGUARD FIDUCIARY TRUST CO	493,373493,373	$11M	0.67%	NEW
33	Bank of New York Mellon Corp	489,497489,497	$11M	0.66%	—
34	Russell Investments Group, Ltd.	469,519469,519	$11M	0.64%	ADD 8%
35	Assenagon Asset Management S.A.	444,222444,222	$10M	0.60%	—
36	UBS Group AG	437,093437,093	$10M	0.59%	TRIM -14%
37	BARCLAYS PLC	430,879430,879	$10M	0.58%	TRIM -27%
38	PRINCIPAL FINANCIAL GROUP INC	418,731418,731	$10M	0.57%	ADD 23%
39	JPMORGAN CHASE & CO	350,571350,571	$8M	0.47%	ADD 134%
40	Balyasny Asset Management L.P.	322,009322,009	$8M	0.44%	ADD 32%
41	FIRST TRUST ADVISORS LP	278,340278,340	$6M	0.38%	ADD 135%
42	CX Institutional	277,532277,532	$6M	0.38%	NEW
43	FRANKLIN RESOURCES INC	257,607257,607	$6M	0.35%	TRIM -81%
44	Public Sector Pension Investment Board	254,164254,164	$6M	0.34%	ADD 3%
45	D. E. Shaw & Co., Inc.	248,819248,819	$6M	0.34%	TRIM -33%
46	VOLORIDGE INVESTMENT MANAGEMENT, LLC	234,359234,359	$5M	0.32%	TRIM -51%
47	Uniplan Investment Counsel, Inc.	229,338229,338	$5M	0.31%	ADD 4%
48	ASSETMARK, INC	205,072205,072	$5M	0.28%	ADD 11%
49	TEACHER RETIREMENT SYSTEM OF TEXAS	200,082200,082	$5M	0.27%	NEW
50	RHUMBLINE ADVISERS	199,898199,898	$5M	0.27%	—
51	AMERIPRISE FINANCIAL INC	192,799192,799	$4M	0.26%	ADD 33%
52	Legal & General Group Plc	187,122187,122	$4M	0.25%	—
53	CITADEL ADVISORS LLC	176,077176,077	$4M	0.24%	—
54	Empowered Funds, LLC	168,055168,055	$4M	0.23%	ADD 125%
55	Integrated Wealth Concepts LLC	165,214165,214	$4M	0.22%	TRIM -10%
56	INTECH INVESTMENT MANAGEMENT LLC	163,301163,301	$4M	0.22%	TRIM -26%
57	EXCHANGE TRADED CONCEPTS, LLC	161,248161,248	$4M	0.22%	TRIM -6%
58	HUSSMAN STRATEGIC ADVISORS, INC.	147,000147,000	$3M	0.20%	ADD 40%
59	NOMURA HOLDINGS INC	144,087144,087	$3M	0.20%	TRIM -42%
60	Swiss National Bank	140,500140,500	$3M	0.19%	ADD 19%
61	PRUDENTIAL FINANCIAL INC	136,417136,417	$3M	0.18%	—
62	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	134,571134,571	$3M	0.18%	ADD 9%
63	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	134,239134,239	$3M	0.18%	—
64	Edgestream Partners, L.P.	132,225132,225	$3M	0.18%	NEW
65	SEI INVESTMENTS CO	131,205131,205	$3M	0.18%	ADD 51%
66	MARTINGALE ASSET MANAGEMENT L P	125,693125,693	$3M	0.17%	ADD 17%
67	Dauntless Investment Group, LLC	122,402122,402	$3M	0.17%	ADD 2110%
68	Gotham Asset Management, LLC	121,799121,799	$3M	0.17%	TRIM -6%
69	Universal- Beteiligungs- und Servicegesellschaft mbH	115,021115,021	$3M	0.16%	TRIM -34%
70	HSBC HOLDINGS PLC	101,608101,608	$2M	0.14%	TRIM -84%
71	QRG CAPITAL MANAGEMENT, INC.	101,311101,311	$2M	0.14%	ADD 27%
72	PRICE T ROWE ASSOCIATES INC /MD/	93,94093,940	$2M	0.13%	ADD 22%
73	O'SHAUGHNESSY ASSET MANAGEMENT, LLC	90,13390,133	$2M	0.12%	—
74	Janney Montgomery Scott LLC	90,00090,000	$2M	0.12%	ADD 20%
75	Orion Porfolio Solutions, LLC	89,97389,973	$2M	0.12%	TRIM -14%
76	Oliver Luxxe Assets LLC	84,96084,960	$2M	0.12%	—
77	Freestone Grove Partners LP	81,84681,846	$2M	0.11%	TRIM -11%
78	Creative Planning	79,77079,770	$2M	0.11%	ADD 14%
79	KLP KAPITALFORVALTNING AS	78,50078,500	$2M	0.11%	ADD 4%
80	JAMES INVESTMENT RESEARCH, INC.	77,22777,227	$2M	0.10%	—
81	NewEdge Wealth, LLC	77,13477,134	$2M	0.10%	ADD 53%
82	BNP PARIBAS FINANCIAL MARKETS	76,51476,514	$2M	0.10%	TRIM -10%
83	Synergy Asset Management, LLC	76,34076,340	$2M	0.10%	ADD 3%
84	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	74,46874,468	$2M	0.10%	ADD 42%
85	Susquehanna Portfolio Strategies, LLC	71,99571,995	$2M	0.10%	TRIM -44%
86	CHASE INVESTMENT COUNSEL CORP	70,00070,000	$2M	0.09%	—
87	JENNISON ASSOCIATES LLC	69,76769,767	$2M	0.09%	ADD 50%
88	LSV ASSET MANAGEMENT	69,32369,323	$2M	0.09%	ADD 20%
89	ALLIANCEBERNSTEIN L.P.	80,65180,651	$2M	0.11%	ADD 21%
90	FMR LLC	68,73068,730	$2M	0.09%	ADD 137%
91	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	68,00068,000	$2M	0.09%	TRIM -79%
92	VANGUARD ASSET MANAGEMENT, Ltd	62,55562,555	$1M	0.08%	NEW
93	ALGERT GLOBAL LLC	60,48060,480	$1M	0.08%	TRIM -49%
94	CANADA LIFE ASSURANCE Co	59,51459,514	$1M	0.08%	TRIM -6%
95	Aquatic Capital Management LLC	56,91356,913	$1M	0.08%	NEW
96	NEW YORK STATE TEACHERS RETIREMENT SYSTEM	54,86754,867	$1M	0.07%	—
97	LOS ANGELES CAPITAL MANAGEMENT LLC	53,53353,533	$1M	0.07%	TRIM -79%
98	RITHOLTZ WEALTH MANAGEMENT	53,18053,180	$1M	0.07%	—
99	HRT FINANCIAL LP	53,13653,136	$1M	0.07%	NEW
100	State of Alaska, Department of Revenue	50,63950,639	$1M	0.07%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

9.5M

9.2M

9.1M

9.4M

10.7M

11.3M

$263M

DIMENSIONAL FUND ADVISORS LP

4.9M

4.7M

4.3M

4.4M

$103M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

4.2M

$98M

RENAISSANCE TECHNOLOGIES LLC

4.3M

4.6M

4.8M

4.6M

4.2M

4.1M

$94M

VANGUARD CAPITAL MANAGEMENT LLC

—

3.1M

$73M

STATE STREET CORP

2.5M

2.4M

2.5M

2.6M

2.8M

3.1M

$71M

MILLENNIUM MANAGEMENT LLC

401K

1.7M

2.0M

1.6M

2.3M

$53M

Sarissa Capital Management LP

7.3M

2.8M

2.1M

$50M

SYSTEMATIC FINANCIAL MANAGEMENT LP

2.0M

2.1M

2.0M

$47M

GEODE CAPITAL MANAGEMENT, LLC

1.4M

1.5M

1.6M

1.8M

1.9M

$45M

AMERICAN CENTURY COMPANIES INC

1.4M

1.7M

2.1M

2.4M

2.2M

1.9M

$45M

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

1.1M

922K

1.7M

2.4M

1.9M

$44M

Boston Partners

490K

623K

875K

1.4M

1.5M

1.7M

$40M

BANK OF AMERICA CORP /DE/

1.1M

1.4M

1.5M

1.6M

$38M

GOLDMAN SACHS GROUP INC

1.7M

1.4M

1.5M

1.2M

1.1M

1.6M

$37M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	284	75,135,931	101.8%	$1.8B
2025-Q4	281	75,624,071	102.5%	$1.5B
2025-Q3	264	75,973,698	102.9%	$1.4B
2025-Q2	267	74,681,901	101.2%	$1.5B
2025-Q1

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · INVA

Activists — 13D, active intent

Sarissa Capital Management LP4.7%▼ -3.7ppSCHEDULE 13D/A · Amd 5 · event 2025-03-13SEC →

2,966,022 shares · 2 reporting persons

Large holders — 13G, passive (top 5 of 8 by % of class)

Holder	% of class	Type	As of
BlackRock, Inc.	14%	QII	2025-03-31	SEC →
DIMENSIONAL FUND ADVISORS LP	5.8%	QII	2025-12-31	SEC →
VANGUARD PORTFOLIO MANAGEMENT LLC	5.79%	QII	2026-03-31	SEC →

Institutional ownership· 13F filers holding INVA · 2026-Q1 methodology → sources →

284 holders

% of shares outstanding held

101.8%

Shares held (13F)

75,135,931

Reporting holders

284

Top holders

largest 100 of 284 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	11,307,84511.3M	$263M	15.32%	ADD 6%
2	DIMENSIONAL FUND ADVISORS LP	4,436,4274.4M	$103M	6.01%	—
3	VANGUARD PORTFOLIO MANAGEMENT LLC	4,224,9514.2M	$98M	5.72%	NEW†
4	RENAISSANCE TECHNOLOGIES LLC	4,055,6324.1M	$94M	5.49%	TRIM -4%
5	VANGUARD CAPITAL MANAGEMENT LLC	3,141,5813.1M	$73M	4.26%	NEW†
6	STATE STREET CORP	3,060,3773.1M	$71M	4.15%	ADD 9%
7	MILLENNIUM MANAGEMENT LLC	2,279,4512.3M	$53M	3.09%	ADD 42%
8	Sarissa Capital Management LP	2,130,9502.1M	$50M	2.89%	TRIM -24%
9	SYSTEMATIC FINANCIAL MANAGEMENT LP	2,024,0822.0M	$47M	2.74%	TRIM -4%
10	GEODE CAPITAL MANAGEMENT, LLC	1,929,7181.9M	$45M	2.61%	ADD 10%
11	AMERICAN CENTURY COMPANIES INC	1,910,0211.9M	$45M	2.59%	TRIM -15%
12	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	1,887,5701.9M	$44M	2.56%	TRIM -20%
13	Boston Partners	1,718,8671.7M	$40M	2.33%	ADD 11%
14	BANK OF AMERICA CORP /DE/	1,619,9941.6M	$38M	2.19%	ADD 7%
15	GOLDMAN SACHS GROUP INC	1,593,3831.6M	$37M	2.16%	ADD 42%
16	MARSHALL WACE, LLP	1,504,4111.5M	$35M	2.04%	ADD 8%
17	TWO SIGMA INVESTMENTS, LP	1,484,2641.5M	$35M	2.01%	ADD 77%
18	MORGAN STANLEY	1,310,7501.3M	$31M	1.78%	TRIM -8%
19	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,163,7131.2M	$27M	1.58%	ADD 14%
20	ROYCE & ASSOCIATES LP	1,061,4481.1M	$25M	1.44%	ADD 15%
21	DEUTSCHE BANK AG\	908,067908,067	$21M	1.23%	ADD 7%
22	Invesco Ltd.	904,282904,282	$21M	1.23%	ADD 9%
23	DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	892,336892,336	$21M	1.21%	ADD 28%
24	Qube Research & Technologies Ltd	786,107786,107	$18M	1.07%	TRIM -35%
25	NORTHERN TRUST CORP	774,303774,303	$18M	1.05%	ADD 11%
26	Man Group plc	744,791744,791	$17M	1.01%	TRIM -12%
27	Nuveen, LLC	620,482620,482	$14M	0.84%	TRIM -4%
28	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	574,825574,825	$13M	0.78%	NEW
29	VICTORY CAPITAL MANAGEMENT INC	523,415523,415	$12M	0.71%	ADD 42%
30	Allianz Asset Management GmbH	519,017519,017	$12M	0.70%	ADD 54%
31	AQR CAPITAL MANAGEMENT LLC	495,841495,841	$12M	0.67%	ADD 34%
32	VANGUARD FIDUCIARY TRUST CO	493,373493,373	$11M	0.67%	NEW
33	Bank of New York Mellon Corp	489,497489,497	$11M	0.66%	—
34	Russell Investments Group, Ltd.	469,519469,519	$11M	0.64%	ADD 8%
35	Assenagon Asset Management S.A.	444,222444,222	$10M	0.60%	—
36	UBS Group AG	437,093437,093	$10M	0.59%	TRIM -14%
37	BARCLAYS PLC	430,879430,879	$10M	0.58%	TRIM -27%
38	PRINCIPAL FINANCIAL GROUP INC	418,731418,731	$10M	0.57%	ADD 23%
39	JPMORGAN CHASE & CO	350,571350,571	$8M	0.47%	ADD 134%
40	Balyasny Asset Management L.P.	322,009322,009	$8M	0.44%	ADD 32%
41	FIRST TRUST ADVISORS LP	278,340278,340	$6M	0.38%	ADD 135%
42	CX Institutional	277,532277,532	$6M	0.38%	NEW
43	FRANKLIN RESOURCES INC	257,607257,607	$6M	0.35%	TRIM -81%
44	Public Sector Pension Investment Board	254,164254,164	$6M	0.34%	ADD 3%
45	D. E. Shaw & Co., Inc.	248,819248,819	$6M	0.34%	TRIM -33%
46	VOLORIDGE INVESTMENT MANAGEMENT, LLC	234,359234,359	$5M	0.32%	TRIM -51%
47	Uniplan Investment Counsel, Inc.	229,338229,338	$5M	0.31%	ADD 4%
48	ASSETMARK, INC	205,072205,072	$5M	0.28%	ADD 11%
49	TEACHER RETIREMENT SYSTEM OF TEXAS	200,082200,082	$5M	0.27%	NEW
50	RHUMBLINE ADVISERS	199,898199,898	$5M	0.27%	—
51	AMERIPRISE FINANCIAL INC	192,799192,799	$4M	0.26%	ADD 33%
52	Legal & General Group Plc	187,122187,122	$4M	0.25%	—
53	CITADEL ADVISORS LLC	176,077176,077	$4M	0.24%	—
54	Empowered Funds, LLC	168,055168,055	$4M	0.23%	ADD 125%
55	Integrated Wealth Concepts LLC	165,214165,214	$4M	0.22%	TRIM -10%
56	INTECH INVESTMENT MANAGEMENT LLC	163,301163,301	$4M	0.22%	TRIM -26%
57	EXCHANGE TRADED CONCEPTS, LLC	161,248161,248	$4M	0.22%	TRIM -6%
58	HUSSMAN STRATEGIC ADVISORS, INC.	147,000147,000	$3M	0.20%	ADD 40%
59	NOMURA HOLDINGS INC	144,087144,087	$3M	0.20%	TRIM -42%
60	Swiss National Bank	140,500140,500	$3M	0.19%	ADD 19%
61	PRUDENTIAL FINANCIAL INC	136,417136,417	$3M	0.18%	—
62	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	134,571134,571	$3M	0.18%	ADD 9%
63	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	134,239134,239	$3M	0.18%	—
64	Edgestream Partners, L.P.	132,225132,225	$3M	0.18%	NEW
65	SEI INVESTMENTS CO	131,205131,205	$3M	0.18%	ADD 51%
66	MARTINGALE ASSET MANAGEMENT L P	125,693125,693	$3M	0.17%	ADD 17%
67	Dauntless Investment Group, LLC	122,402122,402	$3M	0.17%	ADD 2110%
68	Gotham Asset Management, LLC	121,799121,799	$3M	0.17%	TRIM -6%
69	Universal- Beteiligungs- und Servicegesellschaft mbH	115,021115,021	$3M	0.16%	TRIM -34%
70	HSBC HOLDINGS PLC	101,608101,608	$2M	0.14%	TRIM -84%
71	QRG CAPITAL MANAGEMENT, INC.	101,311101,311	$2M	0.14%	ADD 27%
72	PRICE T ROWE ASSOCIATES INC /MD/	93,94093,940	$2M	0.13%	ADD 22%
73	O'SHAUGHNESSY ASSET MANAGEMENT, LLC	90,13390,133	$2M	0.12%	—
74	Janney Montgomery Scott LLC	90,00090,000	$2M	0.12%	ADD 20%
75	Orion Porfolio Solutions, LLC	89,97389,973	$2M	0.12%	TRIM -14%
76	Oliver Luxxe Assets LLC	84,96084,960	$2M	0.12%	—
77	Freestone Grove Partners LP	81,84681,846	$2M	0.11%	TRIM -11%
78	Creative Planning	79,77079,770	$2M	0.11%	ADD 14%
79	KLP KAPITALFORVALTNING AS	78,50078,500	$2M	0.11%	ADD 4%
80	JAMES INVESTMENT RESEARCH, INC.	77,22777,227	$2M	0.10%	—
81	NewEdge Wealth, LLC	77,13477,134	$2M	0.10%	ADD 53%
82	BNP PARIBAS FINANCIAL MARKETS	76,51476,514	$2M	0.10%	TRIM -10%
83	Synergy Asset Management, LLC	76,34076,340	$2M	0.10%	ADD 3%
84	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	74,46874,468	$2M	0.10%	ADD 42%
85	Susquehanna Portfolio Strategies, LLC	71,99571,995	$2M	0.10%	TRIM -44%
86	CHASE INVESTMENT COUNSEL CORP	70,00070,000	$2M	0.09%	—
87	JENNISON ASSOCIATES LLC	69,76769,767	$2M	0.09%	ADD 50%
88	LSV ASSET MANAGEMENT	69,32369,323	$2M	0.09%	ADD 20%
89	ALLIANCEBERNSTEIN L.P.	80,65180,651	$2M	0.11%	ADD 21%
90	FMR LLC	68,73068,730	$2M	0.09%	ADD 137%
91	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	68,00068,000	$2M	0.09%	TRIM -79%
92	VANGUARD ASSET MANAGEMENT, Ltd	62,55562,555	$1M	0.08%	NEW
93	ALGERT GLOBAL LLC	60,48060,480	$1M	0.08%	TRIM -49%
94	CANADA LIFE ASSURANCE Co	59,51459,514	$1M	0.08%	TRIM -6%
95	Aquatic Capital Management LLC	56,91356,913	$1M	0.08%	NEW
96	NEW YORK STATE TEACHERS RETIREMENT SYSTEM	54,86754,867	$1M	0.07%	—
97	LOS ANGELES CAPITAL MANAGEMENT LLC	53,53353,533	$1M	0.07%	TRIM -79%
98	RITHOLTZ WEALTH MANAGEMENT	53,18053,180	$1M	0.07%	—
99	HRT FINANCIAL LP	53,13653,136	$1M	0.07%	NEW
100	State of Alaska, Department of Revenue	50,63950,639	$1M	0.07%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

9.5M

9.2M

9.1M

9.4M

10.7M

11.3M

$263M

DIMENSIONAL FUND ADVISORS LP

4.9M

4.7M

4.3M

4.4M

$103M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

4.2M

$98M

RENAISSANCE TECHNOLOGIES LLC

4.3M

4.6M

4.8M

4.6M

4.2M

4.1M

$94M

VANGUARD CAPITAL MANAGEMENT LLC

—

3.1M

$73M

STATE STREET CORP

2.5M

2.4M

2.5M

2.6M

2.8M

3.1M

$71M

MILLENNIUM MANAGEMENT LLC

401K

1.7M

2.0M

1.6M

2.3M

$53M

Sarissa Capital Management LP

7.3M

2.8M

2.1M

$50M

SYSTEMATIC FINANCIAL MANAGEMENT LP

2.0M

2.1M

2.0M

$47M

GEODE CAPITAL MANAGEMENT, LLC

1.4M

1.5M

1.6M

1.8M

1.9M

$45M

AMERICAN CENTURY COMPANIES INC

1.4M

1.7M

2.1M

2.4M

2.2M

1.9M

$45M

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

1.1M

922K

1.7M

2.4M

1.9M

$44M

Boston Partners

490K

623K

875K

1.4M

1.5M

1.7M

$40M

BANK OF AMERICA CORP /DE/

1.1M

1.4M

1.5M

1.6M

$38M

GOLDMAN SACHS GROUP INC

1.7M

1.4M

1.5M

1.2M

1.1M

1.6M

$37M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	284	75,135,931	101.8%	$1.8B
2025-Q4	281	75,624,071	102.5%	$1.5B
2025-Q3	264	75,973,698	102.9%	$1.4B
2025-Q2	267	74,681,901	101.2%	$1.5B
2025-Q1

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · INVA

Activists — 13D, active intent

Sarissa Capital Management LP4.7%▼ -3.7ppSCHEDULE 13D/A · Amd 5 · event 2025-03-13SEC →

2,966,022 shares · 2 reporting persons

Large holders — 13G, passive (top 5 of 8 by % of class)

Holder	% of class	Type	As of
BlackRock, Inc.	14%	QII	2025-03-31	SEC →
DIMENSIONAL FUND ADVISORS LP	5.8%	QII	2025-12-31	SEC →
VANGUARD PORTFOLIO MANAGEMENT LLC	5.79%	QII	2026-03-31	SEC →

INVA US Equity☆

Institutional ownership· 13F filers holding INVA · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · INVA

Institutional ownership· 13F filers holding INVA · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · INVA

INVA US Equity