FULC US Equity

Fulcrum Therapeutics, Inc.

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Health Care · Pharmaceutical Preparations · CIK 1680581 · FYE 1231

$3.72

-0.01 (-0.27%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding FULC · 2026-Q1 methodology → sources →

168 holders

% of shares outstanding held

107.6%

Shares held (13F)

71,717,059

Reporting holders

168

Institutional 13F holdings sum to 107.6% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 7,967,121 shares (settlement 2026-04-30) accounts for the excess.

Top holders

largest 100 of 168 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	SUVRETTA CAPITAL MANAGEMENT, LLC	6,561,1116.6M	$50M	9.85%	—
2	RA CAPITAL MANAGEMENT, L.P.	6,053,9606.1M	$46M	9.09%	—
3	BlackRock, Inc.	5,390,5935.4M	$41M	8.09%	ADD 26%
4	TCG Crossover Management, LLC	5,250,0005.3M	$40M	7.88%	—
5	BRAIDWELL LP	3,134,9223.1M	$24M	4.70%	ADD 2%
6	Nantahala Capital Management, LLC	3,050,0403.1M	$23M	4.58%	TRIM -29%
7	VANGUARD CAPITAL MANAGEMENT LLC	2,692,9482.7M	$21M	4.04%	NEW†
8	Siren, L.L.C.	2,350,0002.4M	$18M	3.53%	ADD 21%
9	First Turn Management, LLC	2,256,1092.3M	$17M	3.39%	ADD 19%
10	Aberdeen Group plc	2,211,9532.2M	$17M	3.32%	ADD 76%
11	Point72 Asset Management, L.P.	2,074,8552.1M	$16M	3.11%	TRIM -13%
12	GSK plc	1,785,7141.8M	$14M	2.68%	—
13	Balyasny Asset Management L.P.	1,779,9461.8M	$14M	2.67%	ADD 83%
14	Jones Hill Capital LP	1,771,9261.8M	$14M	2.66%	NEW†
15	D. E. Shaw & Co., Inc.	1,623,2811.6M	$12M	2.44%	TRIM -15%
16	STATE STREET CORP	1,549,8511.5M	$12M	2.33%	ADD 54%
17	GEODE CAPITAL MANAGEMENT, LLC	1,486,5421.5M	$11M	2.23%	ADD 34%
18	Alyeska Investment Group, L.P.	1,328,4491.3M	$10M	1.99%	NEW
19	CITADEL ADVISORS LLC	1,292,4861.3M	$10M	1.94%	ADD 7%
20	Assenagon Asset Management S.A.	1,193,8731.2M	$9M	1.79%	NEW
21	DIMENSIONAL FUND ADVISORS LP	1,130,2811.1M	$9M	1.70%	ADD 8%
22	Vestal Point Capital, LP	1,100,0001.1M	$8M	1.65%	ADD 16%
23	Ikarian Capital, LLC	1,049,1611.0M	$8M	1.57%	TRIM -24%
24	Qube Research & Technologies Ltd	974,739974,739	$7M	1.46%	ADD 148%
25	Connor, Clark & Lunn Investment Management Ltd.	736,684736,684	$6M	1.11%	ADD 26%
26	ACADIAN ASSET MANAGEMENT LLC	727,315727,315	$6M	1.09%	—
27	VANGUARD PORTFOLIO MANAGEMENT LLC	599,379599,379	$5M	0.90%	NEW
28	GOLDMAN SACHS GROUP INC	571,909571,909	$4M	0.86%	ADD 77%
29	AQR CAPITAL MANAGEMENT LLC	543,165543,165	$4M	0.82%	ADD 3404%
30	NORTHERN TRUST CORP	472,985472,985	$4M	0.71%	TRIM -14%
31	Trexquant Investment LP	453,529453,529	$3M	0.68%	ADD 28%
32	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	426,869426,869	$3M	0.64%	ADD 10%
33	SILVERARC CAPITAL MANAGEMENT, LLC	419,949419,949	$3M	0.63%	ADD 6%
34	ADAGE CAPITAL PARTNERS GP, L.L.C.	400,000400,000	$3M	0.60%	TRIM -76%
35	Jump Financial, LLC	369,805369,805	$3M	0.55%	ADD 301%
36	MILLENNIUM MANAGEMENT LLC	356,471356,471	$3M	0.53%	ADD 555%
37	VANGUARD FIDUCIARY TRUST CO	329,884329,884	$3M	0.50%	NEW
38	UBS Group AG	315,185315,185	$2M	0.47%	ADD 206%
39	JANE STREET GROUP, LLC	310,417310,417	$2M	0.47%	TRIM -37%
40	BOOTHBAY FUND MANAGEMENT, LLC	303,988303,988	$2M	0.46%	TRIM -41%
41	BESSEMER GROUP INC	286,988286,988	$2M	0.43%	—
42	PANAGORA ASSET MANAGEMENT INC	243,565243,565	$2M	0.37%	NEW
43	DAFNA Capital Management LLC	205,000205,000	$2M	0.31%	NEW
44	Squarepoint Ops LLC	175,944175,944	$1M	0.26%	ADD 167%
45	MORGAN STANLEY	173,337173,337	$1M	0.26%	ADD 5%
46	AMERICAN CENTURY COMPANIES INC	156,242156,242	$1M	0.23%	—
47	STATE OF WISCONSIN INVESTMENT BOARD	154,435154,435	$1M	0.23%	ADD 79%
48	Y-Intercept (Hong Kong) Ltd	153,344153,344	$1M	0.23%	ADD 130%
49	Bank of New York Mellon Corp	149,942149,942	$1M	0.23%	ADD 28%
50	TWO SIGMA INVESTMENTS, LP	139,000139,000	$1M	0.21%	NEW
51	GSA CAPITAL PARTNERS LLP	136,664136,664	$1M	0.21%	ADD 37%
52	Fiduciary Trust Co	136,555136,555	$1M	0.20%	—
53	ADAR1 Capital Management, LLC	130,560130,560	$1M	0.20%	TRIM -90%
54	Nuveen, LLC	129,618129,618	$994,170	0.19%	ADD 16%
55	BANK OF AMERICA CORP /DE/	126,559126,559	$970,708	0.19%	TRIM -45%
56	Engineers Gate Manager LP	126,109126,109	$967,256	0.19%	NEW
57	WELLINGTON MANAGEMENT GROUP LLP	118,600118,600	$909,662	0.18%	TRIM -19%
58	Simplify Asset Management Inc.	115,994115,994	$889,674	0.17%	TRIM -27%
59	Invesco Ltd.	111,125111,125	$852,329	0.17%	TRIM -73%
60	SUSQUEHANNA INTERNATIONAL GROUP, LLP	101,336101,336	$777,247	0.15%	ADD 15%
61	BARCLAYS PLC	88,45888,458	$678,473	0.13%	TRIM -33%
62	PRICE T ROWE ASSOCIATES INC /MD/	80,16980,169	$615,000	0.12%	ADD 26%
63	Russell Investments Group, Ltd.	79,15779,157	$607,139	0.12%	ADD 2115%
64	XTX Topco Ltd	71,60371,603	$549,195	0.11%	ADD 38%
65	RBF Capital, LLC	70,00070,000	$536,900	0.11%	TRIM -57%
66	Atom Investors LP	69,15569,155	$530,419	0.10%	ADD 14%
67	RHUMBLINE ADVISERS	66,17566,175	$507,551	0.10%	ADD 19%
68	Creative Planning	64,08964,089	$491,563	0.10%	ADD 190%
69	FMR LLC	61,04161,041	$468,184	0.09%	ADD 694%
70	HSBC HOLDINGS PLC	58,63658,636	$441,529	0.09%	TRIM -32%
71	FRANKLIN RESOURCES INC	54,66654,666	$419,288	0.08%	ADD 24%
72	GROUP ONE TRADING LLC	53,75653,756	$412,309	0.08%	ADD 55%
73	ALLIANCEBERNSTEIN L.P.	34,57034,570	$390,987	0.05%	ADD 126%
74	Burkehill Global Management, LP	50,00050,000	$383,500	0.08%	—
75	STRS OHIO	49,30049,300	$378,131	0.07%	—
76	DEUTSCHE BANK AG\	48,82848,828	$374,511	0.07%	TRIM -83%
77	Man Group plc	46,11946,119	$353,733	0.07%	ADD 202%
78	EntryPoint Capital, LLC	45,24845,248	$347,052	0.07%	ADD 200%
79	Graham Capital Management, L.P.	42,74142,741	$327,823	0.06%	TRIM -12%
80	Marex Group plc	42,00042,000	$322,140	0.06%	NEW
81	SIMPLEX TRADING, LLC	41,94041,940	$321,679	0.06%	ADD 423%
82	COMMONWEALTH EQUITY SERVICES, LLC	40,29040,290	$309,020	0.06%	—
83	BIT Capital GmbH	40,00040,000	$306,800	0.06%	NEW
84	Matisse Capital	39,64939,649	$304,108	0.06%	ADD 195%
85	Brevan Howard Capital Management LP	39,44439,444	$302,535	0.06%	TRIM -19%
86	Vanguard Global Advisers, LLC	38,51938,519	$295,441	0.06%	NEW
87	Seven Fleet Capital Management LP	38,10038,100	$292,227	0.06%	NEW
88	MetLife Investment Management, LLC	33,16433,164	$254,368	0.05%	ADD 46%
89	ALGERT GLOBAL LLC	33,05033,050	$253,000	0.05%	NEW
90	Woodline Partners LP	30,79330,793	$236,182	0.05%	—
91	COUNTRY TRUST BANK	30,04130,041	$230,414	0.05%	—
92	LMR Partners LLP	30,00030,000	$230,100	0.05%	—
93	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	28,08028,080	$215,374	0.04%	ADD 40%
94	Pale Fire Capital SE	26,10026,100	$200,187	0.04%	NEW
95	Quantinno Capital Management LP	25,66925,669	$196,881	0.04%	TRIM -12%
96	JPMORGAN CHASE & CO	29,79229,792	$196,031	0.04%	ADD 43%
97	CITIGROUP INC	23,43523,435	$179,746	0.04%	TRIM -65%
98	Mariner, LLC	23,26023,260	$178,400	0.03%	NEW
99	ExodusPoint Capital Management, LP	23,17223,172	$177,729	0.03%	NEW
100	WELLS FARGO & COMPANY/MN	22,55122,551	$172,966	0.03%	TRIM -86%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

SUVRETTA CAPITAL MANAGEMENT, LLC

3.3M

5.1M

5.4M

6.6M

$50M

RA CAPITAL MANAGEMENT, L.P.

10.2M

6.1M

$46M

BlackRock, Inc.

5.2M

4.7M

4.4M

3.7M

4.3M

5.4M

$41M

TCG Crossover Management, LLC

5.3M

$40M

BRAIDWELL LP

—

219K

3.1M

$24M

Nantahala Capital Management, LLC

4.8M

4.3M

4.7M

4.3M

3.1M

$23M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.7M

$21M

Siren, L.L.C.

—

1.9M

2.4M

$18M

First Turn Management, LLC

—

1.9M

2.3M

$17M

Aberdeen Group plc

—

59K

138K

1.3M

2.2M

$17M

Point72 Asset Management, L.P.

—

498K

—

2.4M

2.1M

$16M

GSK plc

—

1.8M

$14M

Balyasny Asset Management L.P.

—

1.3M

1.5M

970K

1.8M

$14M

Jones Hill Capital LP

—

1.8M

$14M

D. E. Shaw & Co., Inc.

583K

581K

1.2M

1.4M

1.9M

1.6M

$12M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	168	71,717,059	107.6%	$550M
2025-Q4	172	67,568,151	101.4%	$764M
2025-Q3	129	53,809,194	80.8%	$496M
2025-Q2	122	54,404,866	81.6%	$375M
2025-Q1	117	51,385,780	77.1%	$148M
2024-Q4	119	51,962,447	78.0%	$244M
2024-Q3	130	55,104,871	82.7%	$197M
2024-Q2	121	64,845,453	97.3%	$402M
2024-Q1	126

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · FULC

Large holders — 13G, passive (top 5 of 10 by % of class)

Holder

% of class

Type

As of

TANG CAPITAL MANAGEMENT LLC

10.4%

Passive

2026-07-13

SEC →

RA CAPITAL MANAGEMENT, L.P.

9.9%

Passive

2025-12-31

SEC →

SUVRETTA CAPITAL MANAGEMENT, LLC

9.4%

Passive

2025-03-31

SEC →

EcoR1 Capital, LLC

QII

2026-06-17

SEC →

TCG Crossover GP II, LLC

7.9%

Passive

Institutional ownership· 13F filers holding FULC · 2026-Q1 methodology → sources →

168 holders

% of shares outstanding held

107.6%

Shares held (13F)

71,717,059

Reporting holders

168

Top holders

largest 100 of 168 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	SUVRETTA CAPITAL MANAGEMENT, LLC	6,561,1116.6M	$50M	9.85%	—
2	RA CAPITAL MANAGEMENT, L.P.	6,053,9606.1M	$46M	9.09%	—
3	BlackRock, Inc.	5,390,5935.4M	$41M	8.09%	ADD 26%
4	TCG Crossover Management, LLC	5,250,0005.3M	$40M	7.88%	—
5	BRAIDWELL LP	3,134,9223.1M	$24M	4.70%	ADD 2%
6	Nantahala Capital Management, LLC	3,050,0403.1M	$23M	4.58%	TRIM -29%
7	VANGUARD CAPITAL MANAGEMENT LLC	2,692,9482.7M	$21M	4.04%	NEW†
8	Siren, L.L.C.	2,350,0002.4M	$18M	3.53%	ADD 21%
9	First Turn Management, LLC	2,256,1092.3M	$17M	3.39%	ADD 19%
10	Aberdeen Group plc	2,211,9532.2M	$17M	3.32%	ADD 76%
11	Point72 Asset Management, L.P.	2,074,8552.1M	$16M	3.11%	TRIM -13%
12	GSK plc	1,785,7141.8M	$14M	2.68%	—
13	Balyasny Asset Management L.P.	1,779,9461.8M	$14M	2.67%	ADD 83%
14	Jones Hill Capital LP	1,771,9261.8M	$14M	2.66%	NEW†
15	D. E. Shaw & Co., Inc.	1,623,2811.6M	$12M	2.44%	TRIM -15%
16	STATE STREET CORP	1,549,8511.5M	$12M	2.33%	ADD 54%
17	GEODE CAPITAL MANAGEMENT, LLC	1,486,5421.5M	$11M	2.23%	ADD 34%
18	Alyeska Investment Group, L.P.	1,328,4491.3M	$10M	1.99%	NEW
19	CITADEL ADVISORS LLC	1,292,4861.3M	$10M	1.94%	ADD 7%
20	Assenagon Asset Management S.A.	1,193,8731.2M	$9M	1.79%	NEW
21	DIMENSIONAL FUND ADVISORS LP	1,130,2811.1M	$9M	1.70%	ADD 8%
22	Vestal Point Capital, LP	1,100,0001.1M	$8M	1.65%	ADD 16%
23	Ikarian Capital, LLC	1,049,1611.0M	$8M	1.57%	TRIM -24%
24	Qube Research & Technologies Ltd	974,739974,739	$7M	1.46%	ADD 148%
25	Connor, Clark & Lunn Investment Management Ltd.	736,684736,684	$6M	1.11%	ADD 26%
26	ACADIAN ASSET MANAGEMENT LLC	727,315727,315	$6M	1.09%	—
27	VANGUARD PORTFOLIO MANAGEMENT LLC	599,379599,379	$5M	0.90%	NEW
28	GOLDMAN SACHS GROUP INC	571,909571,909	$4M	0.86%	ADD 77%
29	AQR CAPITAL MANAGEMENT LLC	543,165543,165	$4M	0.82%	ADD 3404%
30	NORTHERN TRUST CORP	472,985472,985	$4M	0.71%	TRIM -14%
31	Trexquant Investment LP	453,529453,529	$3M	0.68%	ADD 28%
32	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	426,869426,869	$3M	0.64%	ADD 10%
33	SILVERARC CAPITAL MANAGEMENT, LLC	419,949419,949	$3M	0.63%	ADD 6%
34	ADAGE CAPITAL PARTNERS GP, L.L.C.	400,000400,000	$3M	0.60%	TRIM -76%
35	Jump Financial, LLC	369,805369,805	$3M	0.55%	ADD 301%
36	MILLENNIUM MANAGEMENT LLC	356,471356,471	$3M	0.53%	ADD 555%
37	VANGUARD FIDUCIARY TRUST CO	329,884329,884	$3M	0.50%	NEW
38	UBS Group AG	315,185315,185	$2M	0.47%	ADD 206%
39	JANE STREET GROUP, LLC	310,417310,417	$2M	0.47%	TRIM -37%
40	BOOTHBAY FUND MANAGEMENT, LLC	303,988303,988	$2M	0.46%	TRIM -41%
41	BESSEMER GROUP INC	286,988286,988	$2M	0.43%	—
42	PANAGORA ASSET MANAGEMENT INC	243,565243,565	$2M	0.37%	NEW
43	DAFNA Capital Management LLC	205,000205,000	$2M	0.31%	NEW
44	Squarepoint Ops LLC	175,944175,944	$1M	0.26%	ADD 167%
45	MORGAN STANLEY	173,337173,337	$1M	0.26%	ADD 5%
46	AMERICAN CENTURY COMPANIES INC	156,242156,242	$1M	0.23%	—
47	STATE OF WISCONSIN INVESTMENT BOARD	154,435154,435	$1M	0.23%	ADD 79%
48	Y-Intercept (Hong Kong) Ltd	153,344153,344	$1M	0.23%	ADD 130%
49	Bank of New York Mellon Corp	149,942149,942	$1M	0.23%	ADD 28%
50	TWO SIGMA INVESTMENTS, LP	139,000139,000	$1M	0.21%	NEW
51	GSA CAPITAL PARTNERS LLP	136,664136,664	$1M	0.21%	ADD 37%
52	Fiduciary Trust Co	136,555136,555	$1M	0.20%	—
53	ADAR1 Capital Management, LLC	130,560130,560	$1M	0.20%	TRIM -90%
54	Nuveen, LLC	129,618129,618	$994,170	0.19%	ADD 16%
55	BANK OF AMERICA CORP /DE/	126,559126,559	$970,708	0.19%	TRIM -45%
56	Engineers Gate Manager LP	126,109126,109	$967,256	0.19%	NEW
57	WELLINGTON MANAGEMENT GROUP LLP	118,600118,600	$909,662	0.18%	TRIM -19%
58	Simplify Asset Management Inc.	115,994115,994	$889,674	0.17%	TRIM -27%
59	Invesco Ltd.	111,125111,125	$852,329	0.17%	TRIM -73%
60	SUSQUEHANNA INTERNATIONAL GROUP, LLP	101,336101,336	$777,247	0.15%	ADD 15%
61	BARCLAYS PLC	88,45888,458	$678,473	0.13%	TRIM -33%
62	PRICE T ROWE ASSOCIATES INC /MD/	80,16980,169	$615,000	0.12%	ADD 26%
63	Russell Investments Group, Ltd.	79,15779,157	$607,139	0.12%	ADD 2115%
64	XTX Topco Ltd	71,60371,603	$549,195	0.11%	ADD 38%
65	RBF Capital, LLC	70,00070,000	$536,900	0.11%	TRIM -57%
66	Atom Investors LP	69,15569,155	$530,419	0.10%	ADD 14%
67	RHUMBLINE ADVISERS	66,17566,175	$507,551	0.10%	ADD 19%
68	Creative Planning	64,08964,089	$491,563	0.10%	ADD 190%
69	FMR LLC	61,04161,041	$468,184	0.09%	ADD 694%
70	HSBC HOLDINGS PLC	58,63658,636	$441,529	0.09%	TRIM -32%
71	FRANKLIN RESOURCES INC	54,66654,666	$419,288	0.08%	ADD 24%
72	GROUP ONE TRADING LLC	53,75653,756	$412,309	0.08%	ADD 55%
73	ALLIANCEBERNSTEIN L.P.	34,57034,570	$390,987	0.05%	ADD 126%
74	Burkehill Global Management, LP	50,00050,000	$383,500	0.08%	—
75	STRS OHIO	49,30049,300	$378,131	0.07%	—
76	DEUTSCHE BANK AG\	48,82848,828	$374,511	0.07%	TRIM -83%
77	Man Group plc	46,11946,119	$353,733	0.07%	ADD 202%
78	EntryPoint Capital, LLC	45,24845,248	$347,052	0.07%	ADD 200%
79	Graham Capital Management, L.P.	42,74142,741	$327,823	0.06%	TRIM -12%
80	Marex Group plc	42,00042,000	$322,140	0.06%	NEW
81	SIMPLEX TRADING, LLC	41,94041,940	$321,679	0.06%	ADD 423%
82	COMMONWEALTH EQUITY SERVICES, LLC	40,29040,290	$309,020	0.06%	—
83	BIT Capital GmbH	40,00040,000	$306,800	0.06%	NEW
84	Matisse Capital	39,64939,649	$304,108	0.06%	ADD 195%
85	Brevan Howard Capital Management LP	39,44439,444	$302,535	0.06%	TRIM -19%
86	Vanguard Global Advisers, LLC	38,51938,519	$295,441	0.06%	NEW
87	Seven Fleet Capital Management LP	38,10038,100	$292,227	0.06%	NEW
88	MetLife Investment Management, LLC	33,16433,164	$254,368	0.05%	ADD 46%
89	ALGERT GLOBAL LLC	33,05033,050	$253,000	0.05%	NEW
90	Woodline Partners LP	30,79330,793	$236,182	0.05%	—
91	COUNTRY TRUST BANK	30,04130,041	$230,414	0.05%	—
92	LMR Partners LLP	30,00030,000	$230,100	0.05%	—
93	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	28,08028,080	$215,374	0.04%	ADD 40%
94	Pale Fire Capital SE	26,10026,100	$200,187	0.04%	NEW
95	Quantinno Capital Management LP	25,66925,669	$196,881	0.04%	TRIM -12%
96	JPMORGAN CHASE & CO	29,79229,792	$196,031	0.04%	ADD 43%
97	CITIGROUP INC	23,43523,435	$179,746	0.04%	TRIM -65%
98	Mariner, LLC	23,26023,260	$178,400	0.03%	NEW
99	ExodusPoint Capital Management, LP	23,17223,172	$177,729	0.03%	NEW
100	WELLS FARGO & COMPANY/MN	22,55122,551	$172,966	0.03%	TRIM -86%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

SUVRETTA CAPITAL MANAGEMENT, LLC

3.3M

5.1M

5.4M

6.6M

$50M

RA CAPITAL MANAGEMENT, L.P.

10.2M

6.1M

$46M

BlackRock, Inc.

5.2M

4.7M

4.4M

3.7M

4.3M

5.4M

$41M

TCG Crossover Management, LLC

5.3M

$40M

BRAIDWELL LP

—

219K

3.1M

$24M

Nantahala Capital Management, LLC

4.8M

4.3M

4.7M

4.3M

3.1M

$23M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.7M

$21M

Siren, L.L.C.

—

1.9M

2.4M

$18M

First Turn Management, LLC

—

1.9M

2.3M

$17M

Aberdeen Group plc

—

59K

138K

1.3M

2.2M

$17M

Point72 Asset Management, L.P.

—

498K

—

2.4M

2.1M

$16M

GSK plc

—

1.8M

$14M

Balyasny Asset Management L.P.

—

1.3M

1.5M

970K

1.8M

$14M

Jones Hill Capital LP

—

1.8M

$14M

D. E. Shaw & Co., Inc.

583K

581K

1.2M

1.4M

1.9M

1.6M

$12M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	168	71,717,059	107.6%	$550M
2025-Q4	172	67,568,151	101.4%	$764M
2025-Q3	129	53,809,194	80.8%	$496M
2025-Q2	122	54,404,866	81.6%	$375M
2025-Q1	117	51,385,780	77.1%	$148M
2024-Q4	119	51,962,447	78.0%	$244M
2024-Q3	130	55,104,871	82.7%	$197M
2024-Q2	121	64,845,453	97.3%	$402M
2024-Q1	126

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · FULC

Large holders — 13G, passive (top 5 of 10 by % of class)

Holder

% of class

Type

As of

TANG CAPITAL MANAGEMENT LLC

10.4%

Passive

2026-07-13

SEC →

RA CAPITAL MANAGEMENT, L.P.

9.9%

Passive

2025-12-31

SEC →

SUVRETTA CAPITAL MANAGEMENT, LLC

9.4%

Passive

2025-03-31

SEC →

EcoR1 Capital, LLC

QII

2026-06-17

SEC →

TCG Crossover GP II, LLC

7.9%

Passive

FULC US Equity☆

Institutional ownership· 13F filers holding FULC · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · FULC

Institutional ownership· 13F filers holding FULC · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · FULC

FULC US Equity