Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-22 | Pena Luis C. | Director,Officer | −Sell | 7,438 | $22.71 | $168,917 |
| 2026-06-22 | Patel Jeegar Pravinkumar | Officer | −Sell | 1,488 | $22.50 | $33,480 |
| 2026-06-22 | Patel Jeegar Pravinkumar | Officer | +Exercise | 1,488 | $3.84 | $5,714 |
| 2026-06-22 | Drew Janice Suzann | Officer | +Exercise | 3,839 | $3.84 | $14,742 |
| 2026-06-22 | Drew Janice Suzann | Officer | −Sell | 20,000 | $22.63 | $452,600 |
| 2026-06-22 | Drew Janice Suzann | Officer | +Exercise | 16,161 | $2.99 | $48,321 |
| 2026-06-02 | Cohen David E | Director | −Sell | 600 | $21.38 | $12,828 |
| 2026-06-02 | Cohen David E | Director | −Sell | 5,456 | $20.21 | $110,266 |
| 2026-06-01 | Pena Luis C. | Director,Officer | −Sell | 16,787 | $22.74 | $381,736 |
| 2026-06-01 | Patel Jeegar Pravinkumar | Officer | −Sell | 16,687 | $22.74 | $379,462 |
| 2026-06-01 | Patel Jeegar Pravinkumar | Officer | +Exercise | 13,512 | $3.84 | $51,886 |
| 2026-05-28 | Carver Kyle | Officer | −Sell | 18,175 | $22.84 | $415,117 |
| 2026-05-28 | Carver Kyle | Officer | +Exercise | 15,000 | $2.99 | $44,850 |
| 2026-05-28 | Moss Gregory S. | Officer | −Sell | 14,223 | $22.83 | $324,711 |
| 2026-05-28 | Moss Gregory S. | Officer | +Exercise | 14,223 | $1.71 | $24,321 |
| 2026-02-17 | RA Capital Healthcare Fund LP | Director | +Grant | 35,868 | $27.88 | $1,000,000 |
| 2026-02-17 | Verduyn-van Weegen Felice Isabel | Director,TenPercentOwner | +Grant | 358,680 | $27.88 | $10M |
| 2026-02-17 | LSP 7 Cooperative UA | Director,TenPercentOwner | +Grant | 358,680 | $27.88 | $10M |
| 2025-12-19 | Hopfner Robert Lorne | Director,TenPercentOwner | +Buy | 1,000 | $17.35 | $17,350 |
| 2025-12-09 | Bauer Eugene | Director,Officer | −Tax w/h | 1,478 | $17.84 | $26,368 |
| 2025-12-09 | Carver Kyle | Officer | −Tax w/h | 13,290 | $17.84 | $237,094 |
| 2025-12-09 | Drew Janice Suzann | Officer | −Tax w/h | 5,074 | $17.84 | $90,520 |
| 2025-12-09 | Moss Gregory S. | Officer | −Tax w/h | 13,624 | $17.84 | $243,052 |
| 2025-12-09 | Patel Jeegar Pravinkumar | Officer | −Tax w/h | 7,513 | $17.84 | $134,032 |
| 2025-12-09 | Pena Luis C. | Director,Officer | −Tax w/h | 28,138 | $17.84 | $501,982 |
| 2025-11-07 | Bauer Eugene | Director,Officer | +Conversion | 25,812 | — | — |
| 2025-11-07 | Carver Kyle | Officer | +Conversion | 3,175 | — | — |
| 2025-11-07 | Cohen David E | Director | +Conversion | 6,056 | — | — |
| 2025-11-07 | Drew Janice Suzann | Officer | +Conversion | 1,587 | — | — |
| 2025-11-07 | Hopfner Robert Lorne | Director,TenPercentOwner | +Conversion | 1,632,441 | — | — |
| 2025-11-07 | Hopfner Robert Lorne | Director,TenPercentOwner | +Conversion | 294,502 | — | — |
| 2025-11-07 | Hopfner Robert Lorne | Director,TenPercentOwner | +Conversion | 1,441,032 | — | — |
| 2025-11-07 | Hopfner Robert Lorne | Director,TenPercentOwner | +Conversion | 3,026 | — | — |
| 2025-11-07 | Moss Gregory S. | Officer | +Conversion | 3,175 | — | — |
| 2025-11-07 | Patel Jeegar Pravinkumar | Officer | +Conversion | 3,175 | — | — |
| 2025-11-07 | Pena Luis C. | Director,Officer | +Conversion | 24,225 | — | — |
| 2025-11-07 | Verduyn-van Weegen Felice Isabel | Director,TenPercentOwner | +Buy | 1,562,500 | $16.00 | $25M |
| 2025-11-07 | Verduyn-van Weegen Felice Isabel | Director,TenPercentOwner | +Conversion | 3,367,133 | — | — |
| 2025-11-07 | LSP 7 Cooperative UA | TenPercentOwner | +Buy | 1,562,500 | $16.00 | $25M |
| 2025-11-07 | LSP 7 Cooperative UA | TenPercentOwner | +Conversion | 3,367,133 | — | — |
| 2025-11-07 | RA CAPITAL MANAGEMENT, L.P. | Director,TenPercentOwner | +Buy | 92,904 | $16.00 | $1M |
| 2025-11-07 | RA CAPITAL MANAGEMENT, L.P. | Director,TenPercentOwner | +Buy | 1,157,096 | $16.00 | $19M |
| 2025-11-07 | RA CAPITAL MANAGEMENT, L.P. | Director,TenPercentOwner | +Conversion | 691,441 | — | — |
| 2025-11-07 | RA CAPITAL MANAGEMENT, L.P. | Director,TenPercentOwner | +Conversion | 1,517,329 | — | — |
| 2025-11-07 | Pivotal bioVenture Partners Fund I G.P., L.P. | Director,TenPercentOwner | +Conversion | 294,502 | — | — |
| 2025-11-07 | Pivotal bioVenture Partners Fund I G.P., L.P. | Director,TenPercentOwner | +Conversion | 1,441,032 | — | — |
| 2025-11-07 | Pivotal bioVenture Partners Fund I G.P., L.P. | Director,TenPercentOwner | +Conversion | 1,632,441 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
