ESPR US Equity

Esperion Therapeutics, Inc.

Nasdaqdelisted+ Compare

Health Care · Pharmaceutical Preparations · CIK 1434868 · FYE 1231

$3.18

—

USD · final close, as of 2026-07-13 · marketstack

Delisted — merged 2026-07-13

Switch Ticker

Institutional ownership· 13F filers holding ESPR · 2026-Q1 methodology → sources →

205 holders

% of shares outstanding held

67.7%

Shares held (13F)

174,393,746

Reporting holders

205

Top holders

largest 100 of 205 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	17,852,42717.9M	$49M	6.93%	—
2	WASATCH ADVISORS LP	15,768,89715.8M	$43M	6.13%	ADD 67%
3	Two Seas Capital LP	11,394,83311.4M	$31M	4.43%	TRIM -4%
4	ORBIMED ADVISORS LLC	10,570,30010.6M	$29M	4.11%	ADD 77%
5	VANGUARD CAPITAL MANAGEMENT LLC	10,433,76010.4M	$29M	4.05%	NEW†
6	TWO SIGMA INVESTMENTS, LP	9,458,7799.5M	$26M	3.67%	ADD 99%
7	MARSHALL WACE, LLP	7,075,0837.1M	$19M	2.75%	ADD 29%
8	STATE STREET CORP	7,055,7947.1M	$19M	2.74%	ADD 19%
9	D. E. Shaw & Co., Inc.	6,540,7856.5M	$18M	2.54%	TRIM -5%
10	GEODE CAPITAL MANAGEMENT, LLC	5,955,7396.0M	$16M	2.31%	ADD 4%
11	AIGH Capital Management LLC	4,400,0004.4M	$12M	1.71%	ADD 10%
12	UBS Group AG	4,291,7114.3M	$12M	1.67%	ADD 1270%
13	ARMISTICE CAPITAL, LLC	3,930,1253.9M	$11M	1.53%	NEW
14	PenderFund Capital Management Ltd.	3,891,9263.9M	$11M	1.51%	TRIM -11%
15	Nuveen, LLC	3,613,7093.6M	$10M	1.40%	—
16	VANGUARD PORTFOLIO MANAGEMENT LLC	3,532,5633.5M	$10M	1.37%	NEW
17	Privium Fund Management B.V.	3,299,4413.3M	$9M	1.28%	NEW
18	MORGAN STANLEY	2,735,6442.7M	$7M	1.06%	TRIM -22%
19	ROYCE & ASSOCIATES LP	2,626,9952.6M	$7M	1.02%	TRIM -27%
20	GOLDMAN SACHS GROUP INC	2,410,4542.4M	$7M	0.94%	TRIM -15%
21	JONES FINANCIAL COMPANIES LLLP	2,135,7412.1M	$6M	0.83%	—
22	NORTHERN TRUST CORP	2,104,0082.1M	$6M	0.82%	ADD 5%
23	Voleon Capital Management LP	1,916,6981.9M	$5M	0.74%	ADD 66%
24	Eversept Partners, LP	1,735,9631.7M	$5M	0.67%	TRIM -55%
25	Velan Capital Investment Management LP	1,720,0001.7M	$5M	0.67%	ADD 42%
26	Point72 Asset Management, L.P.	1,689,3721.7M	$5M	0.66%	NEW
27	RENAISSANCE TECHNOLOGIES LLC	1,620,1001.6M	$4M	0.63%	TRIM -26%
28	VANGUARD FIDUCIARY TRUST CO	1,564,2341.6M	$4M	0.61%	NEW
29	BARCLAYS PLC	1,301,9111.3M	$4M	0.51%	ADD 194%
30	DEUTSCHE BANK AG\	1,093,2911.1M	$3M	0.42%	—
31	Rhenman & Partners Asset Management AB	985,000985,000	$3M	0.38%	NEW
32	SUSQUEHANNA INTERNATIONAL GROUP, LLP	850,505850,505	$2M	0.33%	TRIM -9%
33	Invesco Ltd.	742,640742,640	$2M	0.29%	TRIM -3%
34	Squarepoint Ops LLC	700,153700,153	$2M	0.27%	NEW
35	WELLINGTON MANAGEMENT GROUP LLP	695,848695,848	$2M	0.27%	ADD 9%
36	Jump Financial, LLC	689,874689,874	$2M	0.27%	NEW
37	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	670,285670,285	$2M	0.26%	TRIM -6%
38	MACKENZIE FINANCIAL CORP	659,120659,120	$2M	0.26%	ADD 96%
39	JPMORGAN CHASE & CO	685,666685,666	$2M	0.27%	TRIM -29%
40	HRT FINANCIAL LP	626,922626,922	$2M	0.24%	ADD 162%
41	MILLENNIUM MANAGEMENT LLC	604,345604,345	$2M	0.23%	TRIM -85%
42	LAZARD ASSET MANAGEMENT LLC	580,705580,705	$2M	0.23%	ADD 1621%
43	Bank of New York Mellon Corp	555,177555,177	$2M	0.22%	—
44	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	521,081521,081	$1M	0.20%	NEW
45	CITADEL ADVISORS LLC	467,610467,610	$1M	0.18%	TRIM -38%
46	PRINCIPAL FINANCIAL GROUP INC	422,776422,776	$1M	0.16%	ADD 53%
47	Summit Wealth Group, LLC	405,369405,369	$1M	0.16%	ADD 19%
48	Burkehill Global Management, LP	400,000400,000	$1M	0.16%	—
49	FMR LLC	374,481374,481	$1M	0.15%	ADD 366%
50	ALLIANCEBERNSTEIN L.P.	261,760261,760	$968,512	0.10%	—
51	Man Group plc	339,775339,775	$930,984	0.13%	NEW
52	AQR CAPITAL MANAGEMENT LLC	314,866314,866	$862,733	0.12%	ADD 8%
53	LPL Financial LLC	292,267292,267	$800,812	0.11%	ADD 897%
54	RHUMBLINE ADVISERS	276,401276,401	$757,329	0.11%	ADD 2%
55	STATE OF WISCONSIN INVESTMENT BOARD	260,029260,029	$712,479	0.10%	NEW
56	PRICE T ROWE ASSOCIATES INC /MD/	257,427257,427	$706,000	0.10%	ADD 36%
57	BANK OF AMERICA CORP /DE/	249,395249,395	$683,342	0.10%	TRIM -64%
58	Virtus Investment Advisers, LLC	219,293219,293	$600,863	0.09%	ADD 24%
59	XTX Topco Ltd	214,231214,231	$586,993	0.08%	ADD 32%
60	Gotham Asset Management, LLC	208,451208,451	$571,156	0.08%	NEW
61	Qube Research & Technologies Ltd	208,161208,161	$570,361	0.08%	NEW
62	Eleva Capital SAS	183,047183,047	$501,549	0.07%	NEW
63	Mariner, LLC	173,793173,793	$476,201	0.07%	TRIM -38%
64	UMB Bank, n.a.	170,000170,000	$465,800	0.07%	—
65	Engineers Gate Manager LP	164,773164,773	$451,478	0.06%	NEW
66	BNP PARIBAS FINANCIAL MARKETS	152,340152,340	$417,412	0.06%	TRIM -29%
67	Vanguard Global Advisers, LLC	148,790148,790	$407,685	0.06%	NEW
68	HighTower Advisors, LLC	141,152141,152	$386,756	0.05%	ADD 24%
69	CITIGROUP INC	133,596133,596	$366,053	0.05%	ADD 10%
70	SG Americas Securities, LLC	127,983127,983	$351,000	0.05%	ADD 151%
71	Woodline Partners LP	127,028127,028	$348,057	0.05%	—
72	FRANKLIN RESOURCES INC	126,374126,374	$346,265	0.05%	NEW
73	Summit Financial, LLC	126,373126,373	$346,262	0.05%	ADD 18%
74	ACADIAN ASSET MANAGEMENT LLC	125,942125,942	$343,000	0.05%	ADD 1033%
75	JANE STREET GROUP, LLC	124,140124,140	$340,144	0.05%	TRIM -89%
76	SEI INVESTMENTS CO	116,229116,229	$318,467	0.05%	ADD 53%
77	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	112,469112,469	$308,165	0.04%	ADD 4%
78	CANADA PENSION PLAN INVESTMENT BOARD	108,100108,100	$296,194	0.04%	NEW
79	State of Wyoming	105,182105,182	$288,199	0.04%	ADD 66%
80	Diametric Capital, LP	102,955102,955	$282,096	0.04%	TRIM -39%
81	Round Rock Advisors LLC	101,553101,553	$278,255	0.04%	—
82	Lido Advisors, LLC	99,13999,139	$271,641	0.04%	NEW
83	MetLife Investment Management, LLC	96,65296,652	$264,826	0.04%	TRIM -26%
84	Parallel Advisors, LLC	96,25496,254	$263,737	0.04%	TRIM -10%
85	AXQ CAPITAL, LP	94,15994,159	$257,996	0.04%	NEW
86	Creative Planning	93,49293,492	$256,168	0.04%	TRIM -20%
87	WELLS FARGO & COMPANY/MN	92,88092,880	$254,491	0.04%	TRIM -65%
88	PROFUND ADVISORS LLC	90,44490,444	$247,817	0.04%	ADD 30%
89	Capital Advisors Wealth Management, LLC	87,55587,555	$239,901	0.03%	ADD 30%
90	TOCQUEVILLE ASSET MANAGEMENT L.P.	87,00087,000	$238,380	0.03%	TRIM -19%
91	OSAIC HOLDINGS, INC.	84,43484,434	$231,350	0.03%	TRIM -2%
92	RAYMOND JAMES FINANCIAL INC	77,60777,607	$212,643	0.03%	—
93	Graham Capital Management, L.P.	71,06271,062	$194,710	0.03%	TRIM -56%
94	Police & Firemen's Retirement System of New Jersey	68,79868,798	$188,507	0.03%	ADD 19%
95	MANUFACTURERS LIFE INSURANCE COMPANY, THE	64,52364,523	$176,793	0.03%	TRIM -8%
96	NEW YORK STATE COMMON RETIREMENT FUND	63,90063,900	$175,086	0.02%	—
97	INTECH INVESTMENT MANAGEMENT LLC	62,62062,620	$171,579	0.02%	TRIM -40%
98	PRUDENTIAL FINANCIAL INC	60,33060,330	$165,304	0.02%	ADD 74%
99	Savvy Advisors, Inc.	60,00060,000	$164,400	0.02%	—
100	PINNACLE ASSOCIATES LTD	59,80759,807	$163,871	0.02%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

14.2M

14.5M

14.7M

14.8M

17.7M

17.9M

$49M

WASATCH ADVISORS LP

24.5M

10.9M

10.3M

7.1M

9.4M

15.8M

$43M

Two Seas Capital LP

6.2M

6.9M

10.0M

9.7M

11.9M

11.4M

$31M

ORBIMED ADVISORS LLC

—

6.0M

10.6M

$29M

VANGUARD CAPITAL MANAGEMENT LLC

—

10.4M

$29M

TWO SIGMA INVESTMENTS, LP

3.5M

2.7M

1.8M

2.2M

4.7M

9.5M

$26M

MARSHALL WACE, LLP

—

3.6M

5.3M

2.5M

5.5M

7.1M

$19M

STATE STREET CORP

4.5M

3.8M

4.5M

5.9M

7.1M

$19M

D. E. Shaw & Co., Inc.

252K

276K

—

209K

6.9M

6.5M

$18M

GEODE CAPITAL MANAGEMENT, LLC

4.3M

4.4M

4.6M

4.8M

5.7M

6.0M

$16M

AIGH Capital Management LLC

—

3.0M

4.0M

4.4M

$12M

UBS Group AG

877K

670K

1.5M

1.2M

313K

4.3M

$12M

ARMISTICE CAPITAL, LLC

—

3.9M

$11M

PenderFund Capital Management Ltd.

—

2.0M

6.7M

4.4M

3.9M

$11M

Nuveen, LLC

—

3.1M

423K

3.7M

3.6M

$10M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	205	174,393,746	67.7%	$478M
2025-Q4	200	151,287,354

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · ESPR

Large holders — 13G, passive (top 5 by % of class)

Holder	% of class	Type	As of
GLAZER CAPITAL, LLC	8.15%	Passive	2026-06-01	SEC →
BB BIOTECH AG	4.89973%	Passive	2025-03-04	SEC →
Two Seas Capital LP	4.7%	QII	2025-09-30	SEC →
WASATCH ADVISORS LP	0.7%	QII	2026-06-30	SEC →
VANGUARD GROUP INC	0%	QII	2026-03-13

Institutional ownership· 13F filers holding ESPR · 2026-Q1 methodology → sources →

205 holders

% of shares outstanding held

67.7%

Shares held (13F)

174,393,746

Reporting holders

205

Top holders

largest 100 of 205 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	17,852,42717.9M	$49M	6.93%	—
2	WASATCH ADVISORS LP	15,768,89715.8M	$43M	6.13%	ADD 67%
3	Two Seas Capital LP	11,394,83311.4M	$31M	4.43%	TRIM -4%
4	ORBIMED ADVISORS LLC	10,570,30010.6M	$29M	4.11%	ADD 77%
5	VANGUARD CAPITAL MANAGEMENT LLC	10,433,76010.4M	$29M	4.05%	NEW†
6	TWO SIGMA INVESTMENTS, LP	9,458,7799.5M	$26M	3.67%	ADD 99%
7	MARSHALL WACE, LLP	7,075,0837.1M	$19M	2.75%	ADD 29%
8	STATE STREET CORP	7,055,7947.1M	$19M	2.74%	ADD 19%
9	D. E. Shaw & Co., Inc.	6,540,7856.5M	$18M	2.54%	TRIM -5%
10	GEODE CAPITAL MANAGEMENT, LLC	5,955,7396.0M	$16M	2.31%	ADD 4%
11	AIGH Capital Management LLC	4,400,0004.4M	$12M	1.71%	ADD 10%
12	UBS Group AG	4,291,7114.3M	$12M	1.67%	ADD 1270%
13	ARMISTICE CAPITAL, LLC	3,930,1253.9M	$11M	1.53%	NEW
14	PenderFund Capital Management Ltd.	3,891,9263.9M	$11M	1.51%	TRIM -11%
15	Nuveen, LLC	3,613,7093.6M	$10M	1.40%	—
16	VANGUARD PORTFOLIO MANAGEMENT LLC	3,532,5633.5M	$10M	1.37%	NEW
17	Privium Fund Management B.V.	3,299,4413.3M	$9M	1.28%	NEW
18	MORGAN STANLEY	2,735,6442.7M	$7M	1.06%	TRIM -22%
19	ROYCE & ASSOCIATES LP	2,626,9952.6M	$7M	1.02%	TRIM -27%
20	GOLDMAN SACHS GROUP INC	2,410,4542.4M	$7M	0.94%	TRIM -15%
21	JONES FINANCIAL COMPANIES LLLP	2,135,7412.1M	$6M	0.83%	—
22	NORTHERN TRUST CORP	2,104,0082.1M	$6M	0.82%	ADD 5%
23	Voleon Capital Management LP	1,916,6981.9M	$5M	0.74%	ADD 66%
24	Eversept Partners, LP	1,735,9631.7M	$5M	0.67%	TRIM -55%
25	Velan Capital Investment Management LP	1,720,0001.7M	$5M	0.67%	ADD 42%
26	Point72 Asset Management, L.P.	1,689,3721.7M	$5M	0.66%	NEW
27	RENAISSANCE TECHNOLOGIES LLC	1,620,1001.6M	$4M	0.63%	TRIM -26%
28	VANGUARD FIDUCIARY TRUST CO	1,564,2341.6M	$4M	0.61%	NEW
29	BARCLAYS PLC	1,301,9111.3M	$4M	0.51%	ADD 194%
30	DEUTSCHE BANK AG\	1,093,2911.1M	$3M	0.42%	—
31	Rhenman & Partners Asset Management AB	985,000985,000	$3M	0.38%	NEW
32	SUSQUEHANNA INTERNATIONAL GROUP, LLP	850,505850,505	$2M	0.33%	TRIM -9%
33	Invesco Ltd.	742,640742,640	$2M	0.29%	TRIM -3%
34	Squarepoint Ops LLC	700,153700,153	$2M	0.27%	NEW
35	WELLINGTON MANAGEMENT GROUP LLP	695,848695,848	$2M	0.27%	ADD 9%
36	Jump Financial, LLC	689,874689,874	$2M	0.27%	NEW
37	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	670,285670,285	$2M	0.26%	TRIM -6%
38	MACKENZIE FINANCIAL CORP	659,120659,120	$2M	0.26%	ADD 96%
39	JPMORGAN CHASE & CO	685,666685,666	$2M	0.27%	TRIM -29%
40	HRT FINANCIAL LP	626,922626,922	$2M	0.24%	ADD 162%
41	MILLENNIUM MANAGEMENT LLC	604,345604,345	$2M	0.23%	TRIM -85%
42	LAZARD ASSET MANAGEMENT LLC	580,705580,705	$2M	0.23%	ADD 1621%
43	Bank of New York Mellon Corp	555,177555,177	$2M	0.22%	—
44	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	521,081521,081	$1M	0.20%	NEW
45	CITADEL ADVISORS LLC	467,610467,610	$1M	0.18%	TRIM -38%
46	PRINCIPAL FINANCIAL GROUP INC	422,776422,776	$1M	0.16%	ADD 53%
47	Summit Wealth Group, LLC	405,369405,369	$1M	0.16%	ADD 19%
48	Burkehill Global Management, LP	400,000400,000	$1M	0.16%	—
49	FMR LLC	374,481374,481	$1M	0.15%	ADD 366%
50	ALLIANCEBERNSTEIN L.P.	261,760261,760	$968,512	0.10%	—
51	Man Group plc	339,775339,775	$930,984	0.13%	NEW
52	AQR CAPITAL MANAGEMENT LLC	314,866314,866	$862,733	0.12%	ADD 8%
53	LPL Financial LLC	292,267292,267	$800,812	0.11%	ADD 897%
54	RHUMBLINE ADVISERS	276,401276,401	$757,329	0.11%	ADD 2%
55	STATE OF WISCONSIN INVESTMENT BOARD	260,029260,029	$712,479	0.10%	NEW
56	PRICE T ROWE ASSOCIATES INC /MD/	257,427257,427	$706,000	0.10%	ADD 36%
57	BANK OF AMERICA CORP /DE/	249,395249,395	$683,342	0.10%	TRIM -64%
58	Virtus Investment Advisers, LLC	219,293219,293	$600,863	0.09%	ADD 24%
59	XTX Topco Ltd	214,231214,231	$586,993	0.08%	ADD 32%
60	Gotham Asset Management, LLC	208,451208,451	$571,156	0.08%	NEW
61	Qube Research & Technologies Ltd	208,161208,161	$570,361	0.08%	NEW
62	Eleva Capital SAS	183,047183,047	$501,549	0.07%	NEW
63	Mariner, LLC	173,793173,793	$476,201	0.07%	TRIM -38%
64	UMB Bank, n.a.	170,000170,000	$465,800	0.07%	—
65	Engineers Gate Manager LP	164,773164,773	$451,478	0.06%	NEW
66	BNP PARIBAS FINANCIAL MARKETS	152,340152,340	$417,412	0.06%	TRIM -29%
67	Vanguard Global Advisers, LLC	148,790148,790	$407,685	0.06%	NEW
68	HighTower Advisors, LLC	141,152141,152	$386,756	0.05%	ADD 24%
69	CITIGROUP INC	133,596133,596	$366,053	0.05%	ADD 10%
70	SG Americas Securities, LLC	127,983127,983	$351,000	0.05%	ADD 151%
71	Woodline Partners LP	127,028127,028	$348,057	0.05%	—
72	FRANKLIN RESOURCES INC	126,374126,374	$346,265	0.05%	NEW
73	Summit Financial, LLC	126,373126,373	$346,262	0.05%	ADD 18%
74	ACADIAN ASSET MANAGEMENT LLC	125,942125,942	$343,000	0.05%	ADD 1033%
75	JANE STREET GROUP, LLC	124,140124,140	$340,144	0.05%	TRIM -89%
76	SEI INVESTMENTS CO	116,229116,229	$318,467	0.05%	ADD 53%
77	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	112,469112,469	$308,165	0.04%	ADD 4%
78	CANADA PENSION PLAN INVESTMENT BOARD	108,100108,100	$296,194	0.04%	NEW
79	State of Wyoming	105,182105,182	$288,199	0.04%	ADD 66%
80	Diametric Capital, LP	102,955102,955	$282,096	0.04%	TRIM -39%
81	Round Rock Advisors LLC	101,553101,553	$278,255	0.04%	—
82	Lido Advisors, LLC	99,13999,139	$271,641	0.04%	NEW
83	MetLife Investment Management, LLC	96,65296,652	$264,826	0.04%	TRIM -26%
84	Parallel Advisors, LLC	96,25496,254	$263,737	0.04%	TRIM -10%
85	AXQ CAPITAL, LP	94,15994,159	$257,996	0.04%	NEW
86	Creative Planning	93,49293,492	$256,168	0.04%	TRIM -20%
87	WELLS FARGO & COMPANY/MN	92,88092,880	$254,491	0.04%	TRIM -65%
88	PROFUND ADVISORS LLC	90,44490,444	$247,817	0.04%	ADD 30%
89	Capital Advisors Wealth Management, LLC	87,55587,555	$239,901	0.03%	ADD 30%
90	TOCQUEVILLE ASSET MANAGEMENT L.P.	87,00087,000	$238,380	0.03%	TRIM -19%
91	OSAIC HOLDINGS, INC.	84,43484,434	$231,350	0.03%	TRIM -2%
92	RAYMOND JAMES FINANCIAL INC	77,60777,607	$212,643	0.03%	—
93	Graham Capital Management, L.P.	71,06271,062	$194,710	0.03%	TRIM -56%
94	Police & Firemen's Retirement System of New Jersey	68,79868,798	$188,507	0.03%	ADD 19%
95	MANUFACTURERS LIFE INSURANCE COMPANY, THE	64,52364,523	$176,793	0.03%	TRIM -8%
96	NEW YORK STATE COMMON RETIREMENT FUND	63,90063,900	$175,086	0.02%	—
97	INTECH INVESTMENT MANAGEMENT LLC	62,62062,620	$171,579	0.02%	TRIM -40%
98	PRUDENTIAL FINANCIAL INC	60,33060,330	$165,304	0.02%	ADD 74%
99	Savvy Advisors, Inc.	60,00060,000	$164,400	0.02%	—
100	PINNACLE ASSOCIATES LTD	59,80759,807	$163,871	0.02%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

14.2M

14.5M

14.7M

14.8M

17.7M

17.9M

$49M

WASATCH ADVISORS LP

24.5M

10.9M

10.3M

7.1M

9.4M

15.8M

$43M

Two Seas Capital LP

6.2M

6.9M

10.0M

9.7M

11.9M

11.4M

$31M

ORBIMED ADVISORS LLC

—

6.0M

10.6M

$29M

VANGUARD CAPITAL MANAGEMENT LLC

—

10.4M

$29M

TWO SIGMA INVESTMENTS, LP

3.5M

2.7M

1.8M

2.2M

4.7M

9.5M

$26M

MARSHALL WACE, LLP

—

3.6M

5.3M

2.5M

5.5M

7.1M

$19M

STATE STREET CORP

4.5M

3.8M

4.5M

5.9M

7.1M

$19M

D. E. Shaw & Co., Inc.

252K

276K

—

209K

6.9M

6.5M

$18M

GEODE CAPITAL MANAGEMENT, LLC

4.3M

4.4M

4.6M

4.8M

5.7M

6.0M

$16M

AIGH Capital Management LLC

—

3.0M

4.0M

4.4M

$12M

UBS Group AG

877K

670K

1.5M

1.2M

313K

4.3M

$12M

ARMISTICE CAPITAL, LLC

—

3.9M

$11M

PenderFund Capital Management Ltd.

—

2.0M

6.7M

4.4M

3.9M

$11M

Nuveen, LLC

—

3.1M

423K

3.7M

3.6M

$10M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	205	174,393,746	67.7%	$478M
2025-Q4	200	151,287,354

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · ESPR

Large holders — 13G, passive (top 5 by % of class)

Holder	% of class	Type	As of
GLAZER CAPITAL, LLC	8.15%	Passive	2026-06-01	SEC →
BB BIOTECH AG	4.89973%	Passive	2025-03-04	SEC →
Two Seas Capital LP	4.7%	QII	2025-09-30	SEC →
WASATCH ADVISORS LP	0.7%	QII	2026-06-30	SEC →
VANGUARD GROUP INC	0%	QII	2026-03-13

ESPR US Equity☆

Institutional ownership· 13F filers holding ESPR · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · ESPR

Institutional ownership· 13F filers holding ESPR · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · ESPR

ESPR US Equity