| Date | Event | What happened / filer | Source |
|---|---|---|---|
| 2026-07-02 | 13D/A | Schedule 13D amendment — ≥5% beneficial owner (active intent) · by McDonald Ian | sec.gov ↗ |
| 2026-05-15 | 13G | Schedule 13G filed — ≥5% beneficial owner (passive) · by Vestal Point Capital, LP | sec.gov ↗ |
| 2026-05-15 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by JANUS HENDERSON GROUP PLC | sec.gov ↗ |
| 2026-05-15 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by JANUS HENDERSON GROUP PLC | sec.gov ↗ |
| 2026-05-13 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by Vivo Opportunity Fund Holdings, L.P. | sec.gov ↗ |
| 2026-04-30 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by Cormorant Asset Management, LP | sec.gov ↗ |
| 2026-02-17 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by JANUS HENDERSON GROUP PLC | sec.gov ↗ |
| 2026-02-17 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by Commodore Capital LP | sec.gov ↗ |
| 2026-02-17 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by PERCEPTIVE ADVISORS LLC | sec.gov ↗ |
| 2026-02-06 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by Cormorant Asset Management, LP | sec.gov ↗ |
| 2025-11-14 | 13G | Schedule 13G filed — ≥5% beneficial owner (passive) · by Vivo Opportunity Fund Holdings, L.P. | sec.gov ↗ |
| 2025-11-13 | 13G | Schedule 13G filed — ≥5% beneficial owner (passive) · by Adage Capital Management, L.P. | sec.gov ↗ |
| 2025-11-12 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by Sio Capital Management, LLC | sec.gov ↗ |
| 2025-08-14 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by JANUS HENDERSON GROUP PLC | sec.gov ↗ |
| 2025-08-13 | 13G/A | Schedule 13G amendment — ≥5% beneficial owner (passive) · by Sio Capital Management, LLC | sec.gov ↗ |
8-K item codes from the filing header; 13D/G subject and filer verified against the filing index page.
