CGEM US Equity

Cullinan Therapeutics, Inc.

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Health Care · Biological Products, (No Diagnostic Substances) · CIK 1789972 · FYE 1231

$17.47

+0.04 (+0.23%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding CGEM · 2026-Q1 methodology → sources →

173 holders

% of shares outstanding held

106.7%

Shares held (13F)

65,558,928

Reporting holders

173

Institutional 13F holdings sum to 106.7% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 8,799,071 shares (settlement 2026-04-30) accounts for the excess.

Top holders

largest 100 of 173 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Lynx1 Capital Management LP	8,963,5009.0M	$127M	14.58%	—
2	MPM BIOIMPACT LLC	7,648,2687.6M	$109M	12.44%	—
3	BVF INC/IL	5,750,6835.8M	$82M	9.36%	—
4	BlackRock, Inc.	4,449,9664.4M	$63M	7.24%	—
5	Kynam Capital Management, LP	3,114,1323.1M	$44M	5.07%	—
6	STATE STREET CORP	2,544,1152.5M	$36M	4.14%	ADD 16%
7	VANGUARD CAPITAL MANAGEMENT LLC	2,483,0342.5M	$35M	4.04%	NEW†
8	PRICE T ROWE ASSOCIATES INC /MD/	2,029,7192.0M	$29M	3.30%	ADD 4201%
9	Blue Owl Capital Holdings LP	1,909,7641.9M	$27M	3.11%	TRIM -19%
10	RTW INVESTMENTS, LP	1,705,9601.7M	$24M	2.78%	—
11	Venrock Adviser, LLC	1,379,9651.4M	$20M	2.25%	—
12	GEODE CAPITAL MANAGEMENT, LLC	1,368,2681.4M	$19M	2.23%	ADD 5%
13	Siren, L.L.C.	1,193,4101.2M	$17M	1.94%	—
14	Nextech Invest, Ltd.	1,141,1451.1M	$16M	1.86%	—
15	BOOTHBAY FUND MANAGEMENT, LLC	1,112,8031.1M	$16M	1.81%	TRIM -10%
16	MARSHALL WACE, LLP	1,049,5811.0M	$15M	1.71%	ADD 153%
17	DIMENSIONAL FUND ADVISORS LP	906,028906,028	$13M	1.47%	ADD 7%
18	Point72 Asset Management, L.P.	905,376905,376	$13M	1.47%	ADD 151%
19	Nuveen, LLC	805,700805,700	$11M	1.31%	ADD 39%
20	Affinity Asset Advisors, LLC	781,260781,260	$11M	1.27%	TRIM -60%
21	TWIN FOCUS CAPITAL PARTNERS, LLC	595,489595,489	$8M	0.97%	—
22	MORGAN STANLEY	589,483589,483	$8M	0.96%	TRIM -23%
23	VANGUARD PORTFOLIO MANAGEMENT LLC	552,553552,553	$8M	0.90%	NEW
24	Elmind Capital, LP	530,000530,000	$8M	0.86%	ADD 71%
25	TWO SIGMA INVESTMENTS, LP	522,047522,047	$7M	0.85%	ADD 11%
26	BANK OF AMERICA CORP /DE/	516,724516,724	$7M	0.84%	ADD 49%
27	GOLDMAN SACHS GROUP INC	455,449455,449	$6M	0.74%	TRIM -37%
28	NORTHERN TRUST CORP	449,258449,258	$6M	0.73%	ADD 7%
29	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	432,893432,893	$6M	0.70%	—
30	Soleus Capital Management, L.P.	410,200410,200	$6M	0.67%	NEW
31	TCG Crossover Management, LLC	406,786406,786	$6M	0.66%	NEW
32	DEERFIELD MANAGEMENT COMPANY, L.P.	386,169386,169	$5M	0.63%	—
33	DEUTSCHE BANK AG\	367,906367,906	$5M	0.60%	TRIM -37%
34	AQR CAPITAL MANAGEMENT LLC	360,874360,874	$5M	0.59%	ADD 28%
35	MILLENNIUM MANAGEMENT LLC	346,582346,582	$5M	0.56%	TRIM -4%
36	VANGUARD FIDUCIARY TRUST CO	342,852342,852	$5M	0.56%	NEW
37	RENAISSANCE TECHNOLOGIES LLC	324,111324,111	$5M	0.53%	TRIM -49%
38	GREAT POINT PARTNERS LLC	300,000300,000	$4M	0.49%	TRIM -53%
39	Connor, Clark & Lunn Investment Management Ltd.	289,115289,115	$4M	0.47%	ADD 18%
40	JPMORGAN CHASE & CO	297,231297,231	$4M	0.48%	ADD 102%
41	CITADEL ADVISORS LLC	252,778252,778	$4M	0.41%	ADD 129%
42	Invesco Ltd.	244,150244,150	$3M	0.40%	ADD 87%
43	ORBIMED ADVISORS LLC	243,006243,006	$3M	0.40%	TRIM -10%
44	Susquehanna Portfolio Strategies, LLC	233,842233,842	$3M	0.38%	—
45	PFM Health Sciences, LP	227,406227,406	$3M	0.37%	—
46	UBS Group AG	202,385202,385	$3M	0.33%	TRIM -26%
47	Jump Financial, LLC	193,800193,800	$3M	0.32%	TRIM -47%
48	Longaeva Partners L.P.	183,691183,691	$3M	0.30%	NEW
49	Trexquant Investment LP	168,473168,473	$2M	0.27%	TRIM -56%
50	SCHRODER INVESTMENT MANAGEMENT GROUP	173,740173,740	$2M	0.28%	TRIM -49%
51	WELLINGTON MANAGEMENT GROUP LLP	149,626149,626	$2M	0.24%	TRIM -6%
52	PRUDENTIAL FINANCIAL INC	149,445149,445	$2M	0.24%	NEW
53	CITIGROUP INC	144,111144,111	$2M	0.23%	TRIM -40%
54	AMERICAN CENTURY COMPANIES INC	144,107144,107	$2M	0.23%	—
55	Bank of New York Mellon Corp	143,708143,708	$2M	0.23%	—
56	BARCLAYS PLC	140,295140,295	$2M	0.23%	TRIM -48%
57	Assenagon Asset Management S.A.	138,705138,705	$2M	0.23%	TRIM -13%
58	TD Asset Management Inc	114,400114,400	$2M	0.19%	NEW
59	ALGERT GLOBAL LLC	109,731109,731	$2M	0.18%	TRIM -32%
60	MOORE CAPITAL MANAGEMENT, LP	105,960105,960	$2M	0.17%	NEW
61	Bleichroeder LP	100,000100,000	$1M	0.16%	NEW
62	Y-Intercept (Hong Kong) Ltd	95,41795,417	$1M	0.16%	NEW
63	Cinctive Capital Management LP	94,44494,444	$1M	0.15%	NEW
64	Qube Research & Technologies Ltd	90,31690,316	$1M	0.15%	TRIM -24%
65	MANUFACTURERS LIFE INSURANCE COMPANY, THE	75,31075,310	$1M	0.12%	ADD 348%
66	Quantinno Capital Management LP	72,28272,282	$1M	0.12%	ADD 51%
67	Rafferty Asset Management, LLC	69,48569,485	$987,382	0.11%	ADD 13%
68	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	67,65667,656	$961,392	0.11%	ADD 41%
69	RHUMBLINE ADVISERS	67,51667,516	$959,392	0.11%	—
70	Engineers Gate Manager LP	66,28866,288	$941,953	0.11%	TRIM -4%
71	Mariner, LLC	62,71862,718	$891,100	0.10%	ADD 28%
72	Tidal Investments LLC	62,42162,421	$887,002	0.10%	NEW
73	Tema ETFs LLC	62,42162,421	$887,002	0.10%	ADD 69%
74	Apis Capital Advisors, LLC	60,00060,000	$852,600	0.10%	NEW
75	Creative Planning	59,97459,974	$852,231	0.10%	ADD 50%
76	SUPERSTRING CAPITAL MANAGEMENT LP	59,48459,484	$845,268	0.10%	NEW
77	Swiss National Bank	58,30058,300	$828,443	0.09%	—
78	KENNEDY CAPITAL MANAGEMENT LLC	51,49151,491	$731,687	0.08%	ADD 9%
79	ADAR1 Capital Management, LLC	50,00050,000	$710,500	0.08%	—
80	SUSQUEHANNA INTERNATIONAL GROUP, LLP	47,37747,377	$673,227	0.08%	ADD 19%
81	GSA CAPITAL PARTNERS LLP	43,33943,339	$616,000	0.07%	ADD 59%
82	HRT FINANCIAL LP	38,58638,586	$548,000	0.06%	TRIM -54%
83	ALLIANCEBERNSTEIN L.P.	47,63047,630	$492,971	0.08%	—
84	PROFUND ADVISORS LLC	31,25131,251	$444,077	0.05%	ADD 34%
85	MetLife Investment Management, LLC	30,81630,816	$437,895	0.05%	—
86	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	30,39730,397	$431,941	0.05%	—
87	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	30,15130,151	$424,627	0.05%	ADD 5%
88	BNP PARIBAS FINANCIAL MARKETS	29,54329,543	$419,806	0.05%	TRIM -25%
89	TUDOR INVESTMENT CORP ET AL	28,98828,988	$411,919	0.05%	ADD 186%
90	Optimize Financial Inc	28,15828,158	$400,125	0.05%	NEW
91	Corient Private Wealth LLC	27,88527,885	$396,247	0.05%	NEW
92	IEQ CAPITAL, LLC	27,73627,736	$394,129	0.05%	NEW
93	Vanguard Global Advisers, LLC	27,06627,066	$384,608	0.04%	NEW
94	XTX Topco Ltd	26,32426,324	$374,064	0.04%	TRIM -78%
95	Knott David M Jr	24,20024,200	$343,882	0.04%	NEW
96	Voleon Capital Management LP	24,09224,092	$342,347	0.04%	TRIM -51%
97	Brevan Howard Capital Management LP	24,07824,078	$342,148	0.04%	ADD 119%
98	Virtus Investment Advisers, LLC	22,87522,875	$325,054	0.04%	ADD 2%
99	JANE STREET GROUP, LLC	22,81222,812	$324,159	0.04%	TRIM -88%
100	WELLS FARGO & COMPANY/MN	20,93920,939	$297,543	0.03%	TRIM -65%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Lynx1 Capital Management LP

1.3M

3.2M

4.4M

5.8M

9.0M

$127M

MPM BIOIMPACT LLC

7.6M

$109M

BVF INC/IL

5.8M

$82M

BlackRock, Inc.

4.4M

4.2M

4.4M

$63M

Kynam Capital Management, LP

1.3M

2.3M

2.1M

2.3M

3.1M

$44M

STATE STREET CORP

2.1M

1.8M

1.6M

1.7M

2.2M

2.5M

$36M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.5M

$35M

PRICE T ROWE ASSOCIATES INC /MD/

29K

32K

36K

43K

47K

2.0M

$29M

Blue Owl Capital Holdings LP

2.4M

2.5M

2.4M

1.9M

$27M

RTW INVESTMENTS, LP

1.7M

$24M

Venrock Adviser, LLC

1.4M

$20M

GEODE CAPITAL MANAGEMENT, LLC

1.2M

1.3M

1.4M

$19M

Siren, L.L.C.

1.2M

$17M

Nextech Invest, Ltd.

—

1.1M

$16M

BOOTHBAY FUND MANAGEMENT, LLC

—

1.2M

1.1M

$16M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	173	65,558,928	106.7%	$931M
2025-Q4	153	63,187,651	102.8%	$654M
2025-Q3	145	61,111,186	99.4%	$363M
2025-Q2	144	62,614,695	101.9%	$471M
2025-Q1	149	64,683,974	105.2%	$490M
2024-Q4	147	65,600,623	106.7%	$799M
2024-Q3	137	65,049,846	105.8%	$1.1B
2024-Q2	135	62,964,046	102.5%	$1.1B
2024-Q1	113	41,722,918	67.9%	$711M
2023-Q4	113	37,829,637	61.6%	$385M

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · CGEM

Large holders — 13G, passive (top 5 of 7 by % of class)

Holder

% of class

Type

As of

Lynx1 Capital Management LP

14.5%

Passive

2025-10-08

SEC →

BIOTECHNOLOGY VALUE FUND L P

9.99%

Passive

2026-03-31

SEC →

Kynam Capital Management, LP

5.27%

QII

2025-12-31

SEC →

Flynn James E

4.95%

Passive

2025-09-30

SEC →

FRANKLIN RESOURCES INC

3.8%

QII

Institutional ownership· 13F filers holding CGEM · 2026-Q1 methodology → sources →

173 holders

% of shares outstanding held

106.7%

Shares held (13F)

65,558,928

Reporting holders

173

Top holders

largest 100 of 173 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Lynx1 Capital Management LP	8,963,5009.0M	$127M	14.58%	—
2	MPM BIOIMPACT LLC	7,648,2687.6M	$109M	12.44%	—
3	BVF INC/IL	5,750,6835.8M	$82M	9.36%	—
4	BlackRock, Inc.	4,449,9664.4M	$63M	7.24%	—
5	Kynam Capital Management, LP	3,114,1323.1M	$44M	5.07%	—
6	STATE STREET CORP	2,544,1152.5M	$36M	4.14%	ADD 16%
7	VANGUARD CAPITAL MANAGEMENT LLC	2,483,0342.5M	$35M	4.04%	NEW†
8	PRICE T ROWE ASSOCIATES INC /MD/	2,029,7192.0M	$29M	3.30%	ADD 4201%
9	Blue Owl Capital Holdings LP	1,909,7641.9M	$27M	3.11%	TRIM -19%
10	RTW INVESTMENTS, LP	1,705,9601.7M	$24M	2.78%	—
11	Venrock Adviser, LLC	1,379,9651.4M	$20M	2.25%	—
12	GEODE CAPITAL MANAGEMENT, LLC	1,368,2681.4M	$19M	2.23%	ADD 5%
13	Siren, L.L.C.	1,193,4101.2M	$17M	1.94%	—
14	Nextech Invest, Ltd.	1,141,1451.1M	$16M	1.86%	—
15	BOOTHBAY FUND MANAGEMENT, LLC	1,112,8031.1M	$16M	1.81%	TRIM -10%
16	MARSHALL WACE, LLP	1,049,5811.0M	$15M	1.71%	ADD 153%
17	DIMENSIONAL FUND ADVISORS LP	906,028906,028	$13M	1.47%	ADD 7%
18	Point72 Asset Management, L.P.	905,376905,376	$13M	1.47%	ADD 151%
19	Nuveen, LLC	805,700805,700	$11M	1.31%	ADD 39%
20	Affinity Asset Advisors, LLC	781,260781,260	$11M	1.27%	TRIM -60%
21	TWIN FOCUS CAPITAL PARTNERS, LLC	595,489595,489	$8M	0.97%	—
22	MORGAN STANLEY	589,483589,483	$8M	0.96%	TRIM -23%
23	VANGUARD PORTFOLIO MANAGEMENT LLC	552,553552,553	$8M	0.90%	NEW
24	Elmind Capital, LP	530,000530,000	$8M	0.86%	ADD 71%
25	TWO SIGMA INVESTMENTS, LP	522,047522,047	$7M	0.85%	ADD 11%
26	BANK OF AMERICA CORP /DE/	516,724516,724	$7M	0.84%	ADD 49%
27	GOLDMAN SACHS GROUP INC	455,449455,449	$6M	0.74%	TRIM -37%
28	NORTHERN TRUST CORP	449,258449,258	$6M	0.73%	ADD 7%
29	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	432,893432,893	$6M	0.70%	—
30	Soleus Capital Management, L.P.	410,200410,200	$6M	0.67%	NEW
31	TCG Crossover Management, LLC	406,786406,786	$6M	0.66%	NEW
32	DEERFIELD MANAGEMENT COMPANY, L.P.	386,169386,169	$5M	0.63%	—
33	DEUTSCHE BANK AG\	367,906367,906	$5M	0.60%	TRIM -37%
34	AQR CAPITAL MANAGEMENT LLC	360,874360,874	$5M	0.59%	ADD 28%
35	MILLENNIUM MANAGEMENT LLC	346,582346,582	$5M	0.56%	TRIM -4%
36	VANGUARD FIDUCIARY TRUST CO	342,852342,852	$5M	0.56%	NEW
37	RENAISSANCE TECHNOLOGIES LLC	324,111324,111	$5M	0.53%	TRIM -49%
38	GREAT POINT PARTNERS LLC	300,000300,000	$4M	0.49%	TRIM -53%
39	Connor, Clark & Lunn Investment Management Ltd.	289,115289,115	$4M	0.47%	ADD 18%
40	JPMORGAN CHASE & CO	297,231297,231	$4M	0.48%	ADD 102%
41	CITADEL ADVISORS LLC	252,778252,778	$4M	0.41%	ADD 129%
42	Invesco Ltd.	244,150244,150	$3M	0.40%	ADD 87%
43	ORBIMED ADVISORS LLC	243,006243,006	$3M	0.40%	TRIM -10%
44	Susquehanna Portfolio Strategies, LLC	233,842233,842	$3M	0.38%	—
45	PFM Health Sciences, LP	227,406227,406	$3M	0.37%	—
46	UBS Group AG	202,385202,385	$3M	0.33%	TRIM -26%
47	Jump Financial, LLC	193,800193,800	$3M	0.32%	TRIM -47%
48	Longaeva Partners L.P.	183,691183,691	$3M	0.30%	NEW
49	Trexquant Investment LP	168,473168,473	$2M	0.27%	TRIM -56%
50	SCHRODER INVESTMENT MANAGEMENT GROUP	173,740173,740	$2M	0.28%	TRIM -49%
51	WELLINGTON MANAGEMENT GROUP LLP	149,626149,626	$2M	0.24%	TRIM -6%
52	PRUDENTIAL FINANCIAL INC	149,445149,445	$2M	0.24%	NEW
53	CITIGROUP INC	144,111144,111	$2M	0.23%	TRIM -40%
54	AMERICAN CENTURY COMPANIES INC	144,107144,107	$2M	0.23%	—
55	Bank of New York Mellon Corp	143,708143,708	$2M	0.23%	—
56	BARCLAYS PLC	140,295140,295	$2M	0.23%	TRIM -48%
57	Assenagon Asset Management S.A.	138,705138,705	$2M	0.23%	TRIM -13%
58	TD Asset Management Inc	114,400114,400	$2M	0.19%	NEW
59	ALGERT GLOBAL LLC	109,731109,731	$2M	0.18%	TRIM -32%
60	MOORE CAPITAL MANAGEMENT, LP	105,960105,960	$2M	0.17%	NEW
61	Bleichroeder LP	100,000100,000	$1M	0.16%	NEW
62	Y-Intercept (Hong Kong) Ltd	95,41795,417	$1M	0.16%	NEW
63	Cinctive Capital Management LP	94,44494,444	$1M	0.15%	NEW
64	Qube Research & Technologies Ltd	90,31690,316	$1M	0.15%	TRIM -24%
65	MANUFACTURERS LIFE INSURANCE COMPANY, THE	75,31075,310	$1M	0.12%	ADD 348%
66	Quantinno Capital Management LP	72,28272,282	$1M	0.12%	ADD 51%
67	Rafferty Asset Management, LLC	69,48569,485	$987,382	0.11%	ADD 13%
68	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	67,65667,656	$961,392	0.11%	ADD 41%
69	RHUMBLINE ADVISERS	67,51667,516	$959,392	0.11%	—
70	Engineers Gate Manager LP	66,28866,288	$941,953	0.11%	TRIM -4%
71	Mariner, LLC	62,71862,718	$891,100	0.10%	ADD 28%
72	Tidal Investments LLC	62,42162,421	$887,002	0.10%	NEW
73	Tema ETFs LLC	62,42162,421	$887,002	0.10%	ADD 69%
74	Apis Capital Advisors, LLC	60,00060,000	$852,600	0.10%	NEW
75	Creative Planning	59,97459,974	$852,231	0.10%	ADD 50%
76	SUPERSTRING CAPITAL MANAGEMENT LP	59,48459,484	$845,268	0.10%	NEW
77	Swiss National Bank	58,30058,300	$828,443	0.09%	—
78	KENNEDY CAPITAL MANAGEMENT LLC	51,49151,491	$731,687	0.08%	ADD 9%
79	ADAR1 Capital Management, LLC	50,00050,000	$710,500	0.08%	—
80	SUSQUEHANNA INTERNATIONAL GROUP, LLP	47,37747,377	$673,227	0.08%	ADD 19%
81	GSA CAPITAL PARTNERS LLP	43,33943,339	$616,000	0.07%	ADD 59%
82	HRT FINANCIAL LP	38,58638,586	$548,000	0.06%	TRIM -54%
83	ALLIANCEBERNSTEIN L.P.	47,63047,630	$492,971	0.08%	—
84	PROFUND ADVISORS LLC	31,25131,251	$444,077	0.05%	ADD 34%
85	MetLife Investment Management, LLC	30,81630,816	$437,895	0.05%	—
86	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	30,39730,397	$431,941	0.05%	—
87	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	30,15130,151	$424,627	0.05%	ADD 5%
88	BNP PARIBAS FINANCIAL MARKETS	29,54329,543	$419,806	0.05%	TRIM -25%
89	TUDOR INVESTMENT CORP ET AL	28,98828,988	$411,919	0.05%	ADD 186%
90	Optimize Financial Inc	28,15828,158	$400,125	0.05%	NEW
91	Corient Private Wealth LLC	27,88527,885	$396,247	0.05%	NEW
92	IEQ CAPITAL, LLC	27,73627,736	$394,129	0.05%	NEW
93	Vanguard Global Advisers, LLC	27,06627,066	$384,608	0.04%	NEW
94	XTX Topco Ltd	26,32426,324	$374,064	0.04%	TRIM -78%
95	Knott David M Jr	24,20024,200	$343,882	0.04%	NEW
96	Voleon Capital Management LP	24,09224,092	$342,347	0.04%	TRIM -51%
97	Brevan Howard Capital Management LP	24,07824,078	$342,148	0.04%	ADD 119%
98	Virtus Investment Advisers, LLC	22,87522,875	$325,054	0.04%	ADD 2%
99	JANE STREET GROUP, LLC	22,81222,812	$324,159	0.04%	TRIM -88%
100	WELLS FARGO & COMPANY/MN	20,93920,939	$297,543	0.03%	TRIM -65%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Lynx1 Capital Management LP

1.3M

3.2M

4.4M

5.8M

9.0M

$127M

MPM BIOIMPACT LLC

7.6M

$109M

BVF INC/IL

5.8M

$82M

BlackRock, Inc.

4.4M

4.2M

4.4M

$63M

Kynam Capital Management, LP

1.3M

2.3M

2.1M

2.3M

3.1M

$44M

STATE STREET CORP

2.1M

1.8M

1.6M

1.7M

2.2M

2.5M

$36M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.5M

$35M

PRICE T ROWE ASSOCIATES INC /MD/

29K

32K

36K

43K

47K

2.0M

$29M

Blue Owl Capital Holdings LP

2.4M

2.5M

2.4M

1.9M

$27M

RTW INVESTMENTS, LP

1.7M

$24M

Venrock Adviser, LLC

1.4M

$20M

GEODE CAPITAL MANAGEMENT, LLC

1.2M

1.3M

1.4M

$19M

Siren, L.L.C.

1.2M

$17M

Nextech Invest, Ltd.

—

1.1M

$16M

BOOTHBAY FUND MANAGEMENT, LLC

—

1.2M

1.1M

$16M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	173	65,558,928	106.7%	$931M
2025-Q4	153	63,187,651	102.8%	$654M
2025-Q3	145	61,111,186	99.4%	$363M
2025-Q2	144	62,614,695	101.9%	$471M
2025-Q1	149	64,683,974	105.2%	$490M
2024-Q4	147	65,600,623	106.7%	$799M
2024-Q3	137	65,049,846	105.8%	$1.1B
2024-Q2	135	62,964,046	102.5%	$1.1B
2024-Q1	113	41,722,918	67.9%	$711M
2023-Q4	113	37,829,637	61.6%	$385M

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · CGEM

Large holders — 13G, passive (top 5 of 7 by % of class)

Holder

% of class

Type

As of

Lynx1 Capital Management LP

14.5%

Passive

2025-10-08

SEC →

BIOTECHNOLOGY VALUE FUND L P

9.99%

Passive

2026-03-31

SEC →

Kynam Capital Management, LP

5.27%

QII

2025-12-31

SEC →

Flynn James E

4.95%

Passive

2025-09-30

SEC →

FRANKLIN RESOURCES INC

3.8%

QII

CGEM US Equity☆

Institutional ownership· 13F filers holding CGEM · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · CGEM

Institutional ownership· 13F filers holding CGEM · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · CGEM

CGEM US Equity