| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | JANUS HENDERSON GROUP PLC | 17,534,61217.5M | $148M | 11.65% | ADD 1146% |
| 2 | BlackRock, Inc. | 11,222,40711.2M | $95M | 7.45% | ADD 19% |
| 3 | SUVRETTA CAPITAL MANAGEMENT, LLC | 10,286,93710.3M | $87M | 6.83% | — |
| 4 | STIFEL FINANCIAL CORP | 9,940,8859.9M | $84M | 6.60% | — |
| 5 | STATE STREET CORP | 6,618,8036.6M | $56M | 4.40% | ADD 16% |
| 6 | INFINITUM ASSET MANAGEMENT, LLC | 6,250,0006.3M | $53M | 4.15% | — |
| 7 | TCG Crossover Management, LLC | 4,631,3174.6M | $39M | 3.08% | — |
| 8 | STEMPOINT CAPITAL LP | 3,188,9823.2M | $27M | 2.12% | NEW† |
| 9 | Royalty Pharma Sub-Manager, LLC | 2,936,5072.9M | $25M | 1.95% | — |
| 10 | D. E. Shaw & Co., Inc. | 2,847,1932.8M | $24M | 1.89% | ADD 6% |
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 2,767,7632.8M | $23M | 1.84% | ADD 16% |
| 12 | GOLDMAN SACHS GROUP INC | 2,513,1812.5M | $21M | 1.67% | ADD 28% |
| 13 | Balyasny Asset Management L.P. | 2,445,4162.4M | $21M | 1.62% | ADD 54% |
| 14 | FMR LLC | 2,359,0472.4M | $20M | 1.57% | TRIM -12% |
| 15 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2,279,2752.3M | $19M | 1.51% | NEW |
| 16 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,217,1752.2M | $19M | 1.47% | ADD 10% |
| 17 | AQR CAPITAL MANAGEMENT LLC | 1,975,5162.0M | $17M | 1.31% | ADD 35% |
| 18 | Cormorant Asset Management, LP | 1,760,0001.8M | $15M | 1.17% | ADD 17500% |
| 19 | CITADEL ADVISORS LLC | 1,723,1071.7M | $15M | 1.14% | — |
| 20 | BNP PARIBAS FINANCIAL MARKETS | 1,544,3381.5M | $13M | 1.03% | TRIM -26% |
| 21 | Qube Research & Technologies Ltd | 1,540,4451.5M | $13M | 1.02% | — |
| 22 | ExodusPoint Capital Management, LP | 1,501,0991.5M | $13M | 1.00% | ADD 26% |
| 23 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,497,7931.5M | $13M | 0.99% | ADD 899% |
| 24 | MILLENNIUM MANAGEMENT LLC | 1,447,8861.4M | $12M | 0.96% | ADD 9% |
| 25 | UBS Group AG | 1,426,4271.4M | $12M | 0.95% | ADD 20% |
| 26 | ARS Investment Partners, LLC | 1,378,8281.4M | $12M | 0.92% | ADD 11% |
| 27 | Capital Research Global Investors | 1,332,7921.3M | $11M | 0.89% | — |
| 28 | VANGUARD CAPITAL MANAGEMENT LLC | 1,269,8891.3M | $11M | 0.84% | NEW |
| 29 | MYDA Advisors LLC | 1,225,0001.2M | $10M | 0.81% | TRIM -2% |
| 30 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1,219,8301.2M | $10M | 0.81% | TRIM -8% |
| 31 | TWO SIGMA INVESTMENTS, LP | 1,186,7141.2M | $10M | 0.79% | TRIM -6% |
| 32 | Sio Capital Management, LLC | 1,163,9261.2M | $10M | 0.77% | TRIM -6% |
| 33 | MORGAN STANLEY | 1,026,9321.0M | $9M | 0.68% | ADD 5% |
| 34 | NORTHERN TRUST CORP | 1,001,4101.0M | $8M | 0.67% | ADD 19% |
| 35 | Integral Health Asset Management, LLC | 1,000,0001.0M | $8M | 0.66% | TRIM -33% |
| 36 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 941,077941,077 | $8M | 0.63% | ADD 11% |
| 37 | Simplify Asset Management Inc. | 898,400898,400 | $8M | 0.60% | TRIM -6% |
| 38 | Trexquant Investment LP | 877,774877,774 | $7M | 0.58% | ADD 45% |
| 39 | DAFNA Capital Management LLC | 845,735845,735 | $7M | 0.56% | TRIM -11% |
| 40 | HRT FINANCIAL LP | 833,666833,666 | $7M | 0.55% | ADD 25% |
| 41 | Fiera Capital Corp | 774,168774,168 | $7M | 0.51% | ADD 7% |
| 42 | Aberdeen Group plc | 771,452771,452 | $7M | 0.51% | ADD 11% |
| 43 | BANK OF AMERICA CORP /DE/ | 759,425759,425 | $6M | 0.50% | TRIM -58% |
| 44 | Nuveen, LLC | 745,748745,748 | $6M | 0.50% | — |
| 45 | 5AM Venture Management, LLC | 738,972738,972 | $6M | 0.49% | — |
| 46 | Kynam Capital Management, LP | 702,884702,884 | $6M | 0.47% | — |
| 47 | VANGUARD FIDUCIARY TRUST CO | 701,591701,591 | $6M | 0.47% | NEW |
| 48 | Erste Asset Management GmbH | 693,300693,300 | $6M | 0.46% | — |
| 49 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 618,180618,180 | $5M | 0.41% | ADD 8% |
| 50 | SPHERA FUNDS MANAGEMENT LTD. | 594,000594,000 | $5M | 0.39% | NEW |
| 51 | Sarissa Capital Management LP | 563,184563,184 | $5M | 0.37% | ADD 10% |
| 52 | Pfizer Inc | 505,645505,645 | $4M | 0.34% | — |
| 53 | Burkehill Global Management, LP | 500,000500,000 | $4M | 0.33% | — |
| 54 | JPMORGAN CHASE & CO | 503,565503,565 | $4M | 0.33% | TRIM -15% |
| 55 | RAYMOND JAMES FINANCIAL INC | 446,611446,611 | $4M | 0.30% | ADD 2% |
| 56 | QTR Family Wealth, LLC | 335,980335,980 | $4M | 0.22% | — |
| 57 | Ikarian Capital, LLC | 412,481412,481 | $3M | 0.27% | ADD 94% |
| 58 | XTX Topco Ltd | 408,482408,482 | $3M | 0.27% | ADD 389% |
| 59 | READYSTATE ASSET MANAGEMENT LP | 388,193388,193 | $3M | 0.26% | TRIM -40% |
| 60 | Point72 Asset Management, L.P. | 373,099373,099 | $3M | 0.25% | TRIM -4% |
| 61 | MARSHALL WACE, LLP | 352,605352,605 | $3M | 0.23% | ADD 1074% |
| 62 | ALGERT GLOBAL LLC | 322,750322,750 | $3M | 0.21% | ADD 10% |
| 63 | Defilade Capital Management, L.P. | 315,944315,944 | $3M | 0.21% | NEW |
| 64 | Susquehanna Portfolio Strategies, LLC | 310,647310,647 | $3M | 0.21% | ADD 180% |
| 65 | Bank of New York Mellon Corp | 307,244307,244 | $3M | 0.20% | ADD 13% |
| 66 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 305,567305,567 | $3M | 0.20% | ADD 2235% |
| 67 | Woodline Partners LP | 300,389300,389 | $3M | 0.20% | — |
| 68 | IEQ CAPITAL, LLC | 278,704278,704 | $2M | 0.19% | ADD 71% |
| 69 | Swiss National Bank | 258,600258,600 | $2M | 0.17% | ADD 13% |
| 70 | Invesco Ltd. | 252,931252,931 | $2M | 0.17% | ADD 30% |
| 71 | NewEdge Wealth, LLC | 246,503246,503 | $2M | 0.16% | — |
| 72 | Jump Financial, LLC | 237,373237,373 | $2M | 0.16% | TRIM -3% |
| 73 | JANE STREET GROUP, LLC | 228,444228,444 | $2M | 0.15% | TRIM -73% |
| 74 | Rafferty Asset Management, LLC | 204,548204,548 | $2M | 0.14% | TRIM -2% |
| 75 | Walleye Capital LLC | 203,477203,477 | $2M | 0.14% | TRIM -76% |
| 76 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 202,975202,975 | $2M | 0.13% | ADD 53% |
| 77 | Squarepoint Ops LLC | 177,678177,678 | $2M | 0.12% | NEW |
| 78 | TD Asset Management Inc | 177,390177,390 | $2M | 0.12% | ADD 25% |
| 79 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 172,370172,370 | $1M | 0.11% | ADD 56% |
| 80 | QVT Financial LP | 170,006170,006 | $1M | 0.11% | — |
| 81 | DEUTSCHE BANK AG\ | 162,813162,813 | $1M | 0.11% | ADD 17% |
| 82 | Y-Intercept (Hong Kong) Ltd | 161,876161,876 | $1M | 0.11% | NEW |
| 83 | RENAISSANCE TECHNOLOGIES LLC | 160,952160,952 | $1M | 0.11% | NEW |
| 84 | NEW YORK STATE COMMON RETIREMENT FUND | 160,251160,251 | $1M | 0.11% | — |
| 85 | Empowered Funds, LLC | 148,756148,756 | $1M | 0.10% | ADD 4% |
| 86 | CWM, LLC | 138,410138,410 | $1M | 0.09% | ADD 111% |
| 87 | RHUMBLINE ADVISERS | 136,883136,883 | $1M | 0.09% | ADD 17% |
| 88 | ALLIANCEBERNSTEIN L.P. | 100,036100,036 | $1M | 0.07% | ADD 4% |
| 89 | BOOTHBAY FUND MANAGEMENT, LLC | 127,862127,862 | $1M | 0.08% | ADD 75% |
| 90 | BARCLAYS PLC | 125,822125,822 | $1M | 0.08% | TRIM -61% |
| 91 | DCF Advisers, LLC | 123,500123,500 | $1M | 0.08% | TRIM -18% |
| 92 | ROYAL BANK OF CANADA | 122,452122,452 | $1M | 0.08% | — |
| 93 | Quantinno Capital Management LP | 121,554121,554 | $1M | 0.08% | ADD 190% |
| 94 | Voleon Capital Management LP | 116,880116,880 | $988,805 | 0.08% | TRIM -33% |
| 95 | GSA CAPITAL PARTNERS LLP | 116,798116,798 | $988,000 | 0.08% | ADD 69% |
| 96 | Cerity Partners LLC | 112,825112,825 | $954,499 | 0.07% | ADD 139% |
| 97 | SG Americas Securities, LLC | 102,083102,083 | $864,000 | 0.07% | TRIM -3% |
| 98 | Legal & General Group Plc | 95,98795,987 | $812,051 | 0.06% | TRIM -15% |
| 99 | Mariner, LLC | 95,37695,376 | $806,809 | 0.06% | ADD 95% |
| 100 | WELLS FARGO & COMPANY/MN | 93,04193,041 | $787,127 | 0.06% | TRIM -39% |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 7.0M | 6.4M | 5.1M | 6.8M | 1.4M | 17.5M | $148M |
| BlackRock, Inc. | 7.7M | 7.5M | 7.5M | 7.9M | 9.4M | 11.2M | $95M |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 5.6M | 5.6M | 5.6M | 5.6M | 10.3M | 10.3M | $87M |
| STIFEL FINANCIAL CORP | 6.6M | 6.6M | 6.6M | 6.6M | 9.9M | 9.9M | $84M |
| STATE STREET CORP | 3.5M | 3.4M | 3.5M | 4.3M | 5.7M | 6.6M | $56M |
| INFINITUM ASSET MANAGEMENT, LLC | 110K | 300K | 550K | 1.7M | 6.3M | 6.3M | $53M |
| TCG Crossover Management, LLC | — | — | — | — | 4.6M | 4.6M | $39M |
| STEMPOINT CAPITAL LP | 186K | 251K | 175K | 1.0M | — | 3.2M | $27M |
| Royalty Pharma Sub-Manager, LLC | — | — | — | — | 2.9M | 2.9M | $25M |
| D. E. Shaw & Co., Inc. | 171K | 35K | 519K | 1.3M | 2.7M | 2.8M | $24M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.9M | 2.0M | 2.0M | 2.1M | 2.4M | 2.8M | $23M |
| GOLDMAN SACHS GROUP INC | 817K | 804K | 980K | 1.6M | 2.0M | 2.5M | $21M |
| Balyasny Asset Management L.P. | — | 87K | — | 381K | 1.6M | 2.4M | $21M |
| FMR LLC | 2.1M | 1.9M | 1.7M | 2.4M | 2.7M | 2.4M | $20M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | — | — | — | — | — | 2.3M | $19M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).
| Quarter | Holders | Shares held | % shares out | Value held |
|---|---|---|---|---|
| 2026-Q1 | 273 | 143,560,873 | 95.4% | $1.2B |
| 2025-Q4 | 271 | 121,454,517 | 80.7% | $1.4B |
| 2025-Q3 | 264 | 85,686,134 | 56.9% | $1.3B |
| 2025-Q2 | 249 | 87,141,504 | 57.9% | $1.2B |
| 2025-Q1 | 266 | 91,207,353 | 60.6% | $2.2B |
| 2024-Q4 | 256 | 92,283,434 | 61.3% | $3.5B |
| 2024-Q3 | 253 | 86,976,752 | 57.8% | $4.3B |
| 2024-Q2 | 225 | 83,442,154 | 55.4% | $2.9B |
| 2024-Q1 | 242 | 76,006,116 | 50.5% | $4.2B |
| 2023-Q4 | 218 | 72,513,822 | 48.2% | $3.1B |
| 2023-Q3 | 187 | 61,474,123 | 40.8% | $1.6B |
| 2023-Q2 | 188 | 60,428,758 | 40.1% |
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).
| $1.4B |
| 2023-Q1 | 178 | 70,525,480 | 46.8% | $964M |
| 2022-Q4 | 177 | 62,559,910 | 41.6% | $869M |
| 2022-Q3 | 52 | 9,711,538 | 6.5% | $561M |
