| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | EQT Fund Management S.a r.l. | 5,141,9925.1M | $54M | 15.05% | NEW† |
| 2 | Sanofi | 2,783,0962.8M | $29M | 8.15% | NEW† |
| 3 | Cormorant Asset Management, LP | 2,465,3482.5M | $26M | 7.22% | NEW† |
| 4 | TCG Crossover Management, LLC | 2,053,2332.1M | $22M | 6.01% | NEW† |
| 5 | FEDERATED HERMES, INC. | 1,618,0001.6M | $17M | 4.74% | NEW† |
| 6 | Casdin Capital, LLC | 1,550,0001.6M | $16M | 4.54% | NEW† |
| 7 | ANDERA PARTNERS | 1,538,7021.5M | $16M | 4.50% | NEW† |
| 8 | FMR LLC | 1,458,6771.5M | $15M | 4.27% | NEW† |
| 9 | Nantahala Capital Management, LLC | 1,200,0001.2M | $13M | 3.51% | NEW† |
| 10 | Aberdeen Group plc | 707,656707,656 | $7M | 2.07% | NEW† |
| 11 | PERCEPTIVE ADVISORS LLC | 600,000600,000 | $6M | 1.76% | NEW |
| 12 | SAMSARA BIOCAPITAL, LLC | 600,000600,000 | $6M | 1.76% | NEW |
| 13 | Siren, L.L.C. | 411,250411,250 | $4M | 1.20% | NEW |
| 14 | LMR Partners LLP | 300,000300,000 | $3M | 0.88% | NEW |
| 15 | SEVEN GRAND MANAGERS, LLC | 200,000200,000 | $2M | 0.59% | NEW |
| 16 | Redmile Group, LLC | 156,250156,250 | $2M | 0.46% | NEW |
| 17 | MILLENNIUM MANAGEMENT LLC | 95,23395,233 | $998,994 | 0.28% | NEW |
| 18 | Pfizer Inc | 75,00075,000 | $813,750 | 0.22% | NEW |
| 19 | Alyeska Investment Group, L.P. | 75,00075,000 | $786,750 | 0.22% | NEW |
| 20 | Laurion Capital Management LP | 50,00050,000 | $524,500 | 0.15% | NEW |
| 21 | Bellevue Group AG | 50,00050,000 | $524,500 | 0.15% | NEW |
| 22 | SECTORAL ASSET MANAGEMENT INC | 43,50043,500 | $477,295 | 0.13% | NEW |
| 23 | GOLDMAN SACHS GROUP INC | 35,73935,739 | $374,902 | 0.10% | NEW |
| 24 | CITADEL ADVISORS LLC | 35,00035,000 | $367,150 | 0.10% | NEW |
| 25 | Burkehill Global Management, LP | 35,00035,000 | $367,150 | 0.10% | NEW |
| 26 | HRT FINANCIAL LP | 23,72623,726 | $248,000 | 0.07% | NEW |
| 27 | D. E. Shaw & Co., Inc. | 15,32615,326 | $160,770 | 0.04% | NEW |
| 28 | TWO SIGMA INVESTMENTS, LP | 14,24114,241 | $149,388 | 0.04% | NEW |
| 29 | JANE STREET GROUP, LLC | 12,79412,794 | $134,209 | 0.04% | NEW |
| 30 | UBS Group AG | 6,4376,437 | $67,524 | 0.02% | NEW |
| 31 | MORGAN STANLEY | 3,0253,025 | $31,732 | 0.01% | NEW |
| 32 | SBI Securities Co., Ltd. | 22 | $21 | 0.00% | NEW |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| EQT Fund Management S.a r.l. | — | — | — | — | — | 5.1M | $54M |
| Sanofi | — | — | — | — | — | 2.8M | $29M |
| Cormorant Asset Management, LP | — | — | — | — | — | 2.5M | $26M |
| TCG Crossover Management, LLC | — | — | — | — | — | 2.1M | $22M |
| FEDERATED HERMES, INC. | — | — | — | — | — | 1.6M | $17M |
| Casdin Capital, LLC | — | — | — | — | — | 1.6M | $16M |
| ANDERA PARTNERS | — | — | — | — | — | 1.5M | $16M |
| FMR LLC | — | — | — | — | — | 1.5M | $15M |
| Nantahala Capital Management, LLC | — | — | — | — | — | 1.2M | $13M |
| Aberdeen Group plc | — | — | — | — | — | 708K | $7M |
| PERCEPTIVE ADVISORS LLC | — | — | — | — | — | 600K | $6M |
| SAMSARA BIOCAPITAL, LLC | — | — | — | — | — | 600K | $6M |
| Siren, L.L.C. | — | — | — | — | — | 411K | $4M |
| LMR Partners LLP | — | — | — | — | — | 300K | $3M |
| SEVEN GRAND MANAGERS, LLC | — | — | — | — | — | 200K | $2M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
