Clinical Investigation of Bleeding Reduction Efficacy on Toothpaste Containing 1.05% Chitosan
← catalyst calendarSponsored by Colgate Palmolive (industry) · CL — their whole pipeline →.
Phase
Not applicable
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Prevention
Enrollment
134actual
Sites
1
Country
China
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-04-29 | actual | When the study began enrolling |
| Primary completion | 2025-06-04 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-06-04 | actual | The whole study's end, after follow-up |
| First posted | 2025-05-02 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-08-15 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Bleeding Gum
- Gingivitis
Interventions
- Other: Toothpaste containing 1.05% Chitosan
- Other: Silica-based NaF Toothpaste
- Other: Toothpaste with 67% bicarbonate
Primary outcomes
what the primary-completion date above is the date OFGingival Bleeding
measured From baseline to 3 days, 7 days and 14 days after baseline.
Gingivitis
measured Baseline, and immediately post-brushing
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