LEGION™ Revision Metal Hypersensitivity Study
← catalyst calendarSponsored by Smith & Nephew, Inc. (industry) · SNN — their whole pipeline →.
Phase
Not applicable
Status
Withdrawn
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
0actual
Sites
3
Countries
Canada, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Why the sponsor stopped it
Overhaul of Study Design
As filed on the registry record, in the sponsor's own words.
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | Jan 2016 | not stated | When the study began enrolling |
| Primary completion | Apr 2025 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Apr 2025 | estimated | The whole study's end, after follow-up |
| First posted | 2015-04-09 | estimated | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2016-03-09 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Total Knee Replacement Revision
Interventions
- Device: LEGION OXINIUM
- Device: LEGION Cobalt Chrome
Primary outcome
what the primary-completion date above is the date OFMajor modified Lymphocyte Transformation Tests (Cobalt, Chromium and Nickel) measurements
measured 3,650 Days
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