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BIO vs ILMN

Bio-Rad Laboratories, Inc. (BIO) and Illumina, Inc. (ILMN) are both filed with the SEC under Laboratory Analytical Instruments. ILMN is 3.2× BIO's size by market cap ($34.4B against $10.8B); ILMN trades at the higher fiscal-year P/E (41.8× against 14.0×); BIO reports the higher net margin (29.4% against 19.6%); ILMN grew sales faster over three years (-1.8% against -2.7%); and over the past year ILMN returned +117.4% against BIO's +32.0%.

BIOILMN
Last close$387.70$215.59
Market cap$10.8B$34.4B
P/E (FY)14.0×41.8×
P/S4.2×7.9×
EV/EBITDA49.2×
Gross margin51.9%66.1%
Operating margin1.8%18.6%
Net margin29.4%19.6%
Return on equity10.8%33.4%
Sales growth (3y)-2.7%-1.8%
1-year return+32.0%+117.4%

Screener snapshot — prices as of 2026-08-28. Each side's last close is the most recent session the snapshot holds for that company, which can be an earlier one, and its 1-year return is measured to that close. Market caps struck on 2026-08-27. Last close, market cap and the 1-year return are price figures; every other row is computed over the company's latest filed fiscal year, and the two differ: BIO FY2025 (ended 2025-12-31); ILMN FY2025 (ended 2025-12-28). — not published for this company. A ratio goes unpublished for more than one reason: a component the calculation needs is not on file, the filing does not tag the line it is read from, or the calculation is not defined on the filed basis — EV/EBITDA is not printed on non-positive EBITDA, and return on equity is not computed on a zero or negative equity base.

Who holds them, and who has traded them

BIOILMN
Institutional holders (13F)390840
Insider buyers − sellers (180d)-5
Congressional trades disclosed (180d)00
Executive-branch officials on file — trades disclosed (180d)02

Counts only. The congressional figures count transactions dated in the trailing 180 days and disclosed in STOCK Act periodic transaction reports; amounts are filed as ranges and are never summed. The executive-branch figures count the same window of transactions, and they are scoped to one roster. The officials OGE posts for direct download. Insider buyers − sellers counts distinct people filing open-market Form 4 purchases minus distinct people filing open-market sales over the trailing 180 days, capped at ±5. — no open-market Form 4 purchases or sales in the window.

BIO vs ILMN: common questions

Is BIO bigger than ILMN?
ILMN carries the larger market cap — $34.4B against $10.8B, both struck on 2026-08-27.
Which trades at a higher P/E, BIO or ILMN?
ILMN, at a fiscal-year 41.8× against 14.0× for BIO. Both are price ÷ latest full-year diluted earnings per share, not a trailing-twelve-month P/E.
How have BIO and ILMN performed over the past year?
ILMN returned +117.4% and BIO +32.0%, measured on the trailing calendar year to the last close.
How many institutions hold BIO and ILMN?
390 13F filers report a position in BIO and 840 in ILMN, on the latest quarter in the panel.
Are BIO and ILMN in the same industry?
Both are filed with the SEC under Laboratory Analytical Instruments, which is the classification this pairing is built on.

BIO overview · ILMN overview · BIO institutional ownership · ILMN institutional ownership · Executive branch and ILMN

More in Laboratory Analytical Instruments: A vs BIO · A vs ILMN · A vs RVTY · A vs WAT

Stock comparisons lists every pair this site publishes.

Source: SPZCO — https://spzco.com/vs/bio-vs-ilmn