Clinical trials
catalyst calendar across sponsors →Studies where TALK is the lead sponsor, as filed with ClinicalTrials.gov. Completion dates are the sponsor's own projected windows and are revised as a study runs. Active studies first, then completed and stopped — newest readout first within each.
2 interventional · 1 observational · 1 with posted results
Held by 15 tracked-famous managers (Balyasny Asset Management L.P., SOROS FUND MANAGEMENT LLC, Qube Research & Technologies Ltd, RENAISSANCE TECHNOLOGIES LLC, Schonfeld Strategic Advisors LLC, +10 more) · FINRA short interest 3.6 days to cover (settled 2026-07-31) · insider 90d: 0 buys / 5 sells · government filings 180d: none disclosed
| Study | Phase | Status | Interventions | Conditions | Enrollment | Primary completion | Updated |
|---|---|---|---|---|---|---|---|
| Message-Based Psychotherapy and Digital Treatment Sequences for DepressionNCT04513080results2025-10-30Change in Neuro-QOL - Ability to Participate in Social Roles and ActivitiesRandomized · Single-masked · TreatmentStudy Protocol and Statistical Analysis Plan ↗ · Informed Consent Form ↗ | Not applicable | Completed | Behavioral: Video-Chat Psychotherapy (VCP), Message-Based Psychotherapy (MBP), Message-Based Psychotherapy with Monthly Video-Chat Psychotherapy, Message-Based Psychotherapy with Weekly Video-Chat Psychotherapy, High Monetary Incentive (HMI), Low Monetary and Alternative Incentive (LMAI) | Study Adherence, Depressive Disorder | 1,184 | 2024-01-14actual | 2025-10-30 |
| Comparing Message-based Psychotherapy to Once-weekly, Video-based Psychotherapy for Moderate Depression and AnxietyNCT05467787Change in Patient Health Questionnaire (PHQ-9)Randomized · Single-masked · Treatment | Not applicable | Completed | Behavioral: Message-based psychotherapy (MBP), Video-chat Psychotherapy (VCP) | Depression, Anxiety | 83 | 2020-11-01actual | 2023-04-28 |
| Messaging Therapy for Depression and Anxiety: A Longitudinal Effectiveness StudyNCT03699488observationalChange from Baseline in Depressive symptoms on the Patient Health Questionnaire - 9 | — | Completed | Behavioral: psychotherapy via asynchronous message | Depressive Symptoms, Anxiety Disorders | 12,980 | 2018-02-01actual | 2019-02-06 |
Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.
Source: ClinicalTrials.gov, retrieved 2026-08-19