Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-25 | Burrows Scott L | Officer | +Exercise | 15,000 | $14.50 | $217,500 |
| 2026-06-25 | Burrows Scott L | Officer | −Sell | 10,000 | $87.14 | $871,400 |
| 2026-06-25 | Burrows Scott L | Officer | −Sell | 5,000 | $87.12 | $435,600 |
| 2026-06-23 | Fairmount Funds Management LLC | Director | −Sell | 4,684,781 | $85.31 | $400M |
| 2026-06-23 | Fairmount Funds Management LLC | Director | +Conversion | 666,680 | — | — |
| 2026-06-22 | HENDERSON MICHAEL THOMAS | Director | −Sell | 20,000 | $100.00 | $2M |
| 2026-06-03 | Sloan Sheldon | Officer | −Sell | 8,333 | $75.00 | $624,975 |
| 2026-06-03 | Sloan Sheldon | Officer | +Exercise | 8,333 | $27.46 | $228,824 |
| 2026-06-01 | Burrows Scott L | Officer | +Exercise | 7,500 | $14.50 | $108,750 |
| 2026-06-01 | Burrows Scott L | Officer | −Sell | 1,801 | $69.75 | $125,620 |
| 2026-06-01 | Burrows Scott L | Officer | −Sell | 2,599 | $70.77 | $183,931 |
| 2026-06-01 | Burrows Scott L | Officer | −Sell | 3,100 | $72.06 | $223,386 |
| 2026-06-01 | Turtle Cameron | Director,Officer | −Sell | 3,557 | $69.40 | $246,856 |
| 2026-06-01 | Turtle Cameron | Director,Officer | −Sell | 8,149 | $70.50 | $574,505 |
| 2026-06-01 | Turtle Cameron | Director,Officer | −Sell | 3,294 | $71.38 | $235,126 |
| 2026-05-08 | HENDERSON MICHAEL THOMAS | Director | −Sell | 33,513 | $73.72 | $2M |
| 2026-05-08 | HENDERSON MICHAEL THOMAS | Director | −Sell | 19,269 | $75.35 | $1M |
| 2026-05-08 | HENDERSON MICHAEL THOMAS | Director | −Sell | 24,814 | $74.76 | $2M |
| 2026-05-08 | HENDERSON MICHAEL THOMAS | Director | −Sell | 2,404 | $72.57 | $174,458 |
| 2026-05-01 | Turtle Cameron | Director,Officer | −Sell | 1,700 | $74.23 | $126,191 |
| 2026-05-01 | Turtle Cameron | Director,Officer | −Sell | 300 | $74.96 | $22,488 |
| 2026-05-01 | Turtle Cameron | Director,Officer | −Sell | 5,300 | $69.54 | $368,562 |
| 2026-05-01 | Turtle Cameron | Director,Officer | −Sell | 3,600 | $70.77 | $254,772 |
| 2026-05-01 | Turtle Cameron | Director,Officer | −Sell | 1,000 | $71.76 | $71,760 |
| 2026-05-01 | Turtle Cameron | Director,Officer | −Sell | 3,100 | $73.14 | $226,734 |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 21,306 | $69.53 | $1M |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 400 | $75.37 | $30,148 |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 19,656 | $70.61 | $1M |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 8,777 | $71.56 | $628,082 |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 12,777 | $72.94 | $931,954 |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 10,358 | $73.74 | $763,799 |
| 2026-05-01 | Sloan Sheldon | Officer | −Sell | 5,059 | $74.60 | $377,401 |
| 2026-05-01 | Sloan Sheldon | Officer | +Exercise | 78,333 | $27.46 | $2M |
| 2026-05-01 | Burrows Scott L | Officer | +Exercise | 12,500 | $14.50 | $181,250 |
| 2026-05-01 | Burrows Scott L | Officer | −Sell | 12,500 | $71.37 | $892,125 |
| 2026-04-01 | Burrows Scott L | Officer | −Sell | 1,300 | $49.98 | $64,974 |
| 2026-04-01 | Burrows Scott L | Officer | −Sell | 6,200 | $49.21 | $305,102 |
| 2026-04-01 | Burrows Scott L | Officer | +Exercise | 7,500 | $14.50 | $108,750 |
| 2026-04-01 | Sloan Sheldon | Officer | +Exercise | 7,958 | $21.66 | $172,370 |
| 2026-04-01 | Sloan Sheldon | Officer | −Sell | 7,958 | $50.00 | $397,900 |
| 2026-04-01 | Turtle Cameron | Director,Officer | −Sell | 12,344 | $49.20 | $607,325 |
| 2026-04-01 | Turtle Cameron | Director,Officer | −Sell | 2,656 | $49.92 | $132,588 |
| 2026-03-03 | Burrows Scott L | Officer | +Exercise | 2,500 | $14.50 | $36,250 |
| 2026-03-03 | Burrows Scott L | Officer | −Sell | 2,300 | $40.56 | $93,288 |
| 2026-03-03 | Burrows Scott L | Officer | −Sell | 200 | $41.66 | $8,332 |
| 2026-03-02 | Turtle Cameron | Director,Officer | −Sell | 5,900 | $41.73 | $246,207 |
| 2026-03-02 | Turtle Cameron | Director,Officer | −Sell | 9,100 | $42.49 | $386,659 |
| 2026-02-02 | Turtle Cameron | Director,Officer | −Sell | 14,043 | $32.87 | $461,593 |
| 2026-02-02 | Turtle Cameron | Director,Officer | −Sell | 957 | $31.82 | $30,452 |
| 2026-01-21 | HENDERSON MICHAEL THOMAS | Director | +Other | 63,227 | — | — |
| 2026-01-02 | Turtle Cameron | Director,Officer | −Sell | 2,191 | $31.79 | $69,652 |
| 2026-01-02 | Turtle Cameron | Director,Officer | −Sell | 100 | $32.39 | $3,239 |
| 2026-01-02 | Turtle Cameron | Director,Officer | −Sell | 12,709 | $30.47 | $387,243 |
| 2025-12-01 | Turtle Cameron | Director,Officer | −Sell | 10,995 | $28.73 | $315,886 |
| 2025-12-01 | Turtle Cameron | Director,Officer | −Sell | 4,005 | $29.83 | $119,469 |
| 2025-11-03 | Turtle Cameron | Director,Officer | −Sell | 16,845 | $23.66 | $398,553 |
| 2025-11-03 | Turtle Cameron | Director,Officer | −Sell | 28,155 | $23.13 | $651,225 |
| 2025-09-02 | Burrows Scott L | Officer | −Sell | 18,428 | $16.26 | $299,639 |
| 2025-01-10 | HENDERSON MICHAEL THOMAS | Director | +Other | 105,379 | — | — |
| 2024-11-06 | Albers Jeffrey W. | Director | −Sell | 6,700 | $36.76 | $246,292 |
| 2024-10-25 | Albers Jeffrey W. | Director | −Sell | 300 | $36.43 | $10,929 |
| 2024-09-03 | Burrows Scott L | Officer | −Sell | 18,531 | $28.17 | $522,018 |
| 2024-04-25 | Harwin Peter Evan | Director | +Exercise | 3,639,680 | — | — |
| 2024-02-15 | Turtle Cameron | Director,Officer | +Grant | 400 | $9.82 | $3,928 |
| 2023-12-29 | Fairmount Healthcare Fund II L.P. | Director,TenPercentOwner | −Other | 3,435,480 | — | — |
| 2023-12-29 | Fairmount Healthcare Fund II L.P. | Director,TenPercentOwner | +Other | 406,038 | — | — |
| 2023-12-29 | Fairmount Healthcare Fund II L.P. | Director,TenPercentOwner | +Other | 406,038 | — | — |
| 2023-12-22 | Burrows Scott L | Officer | +Grant | 134,953 | — | — |
| 2023-11-24 | Albers Jeffrey W. | Director | +Conversion | 34,360 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
