SUPN US Equity

SUPERNUS PHARMACEUTICALS, INC.

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Health Care · Pharmaceutical Preparations · CIK 1356576 · FYE 1231

$46.57

-1.16 (-2.43%)

USD · as of 2026-07-29 · marketstack

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Institutional ownership· 13F filers holding SUPN · 2026-Q1 methodology → sources →

325 holders

% of shares outstanding held

100.3%

Shares held (13F)

58,220,249

Reporting holders

325

Institutional 13F holdings sum to 100.3% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 4,721,234 shares (settlement 2026-04-30) accounts for the excess.

Top holders

largest 100 of 325 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	8,797,2548.8M	$455M	15.16%	—
2	MILLENNIUM MANAGEMENT LLC	3,315,9733.3M	$171M	5.71%	ADD 26%
3	VANGUARD PORTFOLIO MANAGEMENT LLC	3,238,6933.2M	$167M	5.58%	NEW†
4	VANGUARD CAPITAL MANAGEMENT LLC	2,467,2152.5M	$128M	4.25%	NEW†
5	DIMENSIONAL FUND ADVISORS LP	2,307,0302.3M	$119M	3.97%	TRIM -15%
6	STATE STREET CORP	2,288,1272.3M	$118M	3.94%	ADD 3%
7	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	2,037,2022.0M	$105M	3.51%	TRIM -12%
8	ARMISTICE CAPITAL, LLC	1,895,3471.9M	$98M	3.27%	TRIM -31%
9	RENAISSANCE TECHNOLOGIES LLC	1,705,2221.7M	$88M	2.94%	—
10	GEODE CAPITAL MANAGEMENT, LLC	1,623,5141.6M	$84M	2.80%	ADD 10%
11	CITADEL ADVISORS LLC	1,493,4461.5M	$77M	2.57%	ADD 230%
12	LOOMIS SAYLES & CO L P	1,425,7791.4M	$74M	2.46%	—
13	Stephens Investment Management Group LLC	1,351,3311.4M	$70M	2.33%	TRIM -4%
14	Point72 Asset Management, L.P.	1,318,5551.3M	$68M	2.27%	TRIM -42%
15	GW&K Investment Management, LLC	1,055,1841.1M	$55M	1.82%	TRIM -2%
16	Sofinnova Investments, Inc.	954,309954,309	$49M	1.64%	ADD 73%
17	MORGAN STANLEY	913,893913,893	$47M	1.57%	TRIM -15%
18	GOLDMAN SACHS GROUP INC	856,487856,487	$44M	1.48%	ADD 30%
19	BANK OF AMERICA CORP /DE/	714,226714,226	$37M	1.23%	ADD 37%
20	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	705,976705,976	$36M	1.22%	—
21	NORTHERN TRUST CORP	699,456699,456	$36M	1.21%	ADD 4%
22	ASHFORD CAPITAL MANAGEMENT INC	645,381645,381	$33M	1.11%	ADD 5%
23	Freestone Grove Partners LP	641,319641,319	$33M	1.10%	ADD 227%
24	D. E. Shaw & Co., Inc.	622,450622,450	$32M	1.07%	TRIM -12%
25	Assenagon Asset Management S.A.	530,618530,618	$27M	0.91%	NEW
26	VICTORY CAPITAL MANAGEMENT INC	502,406502,406	$26M	0.87%	TRIM -5%
27	Qube Research & Technologies Ltd	498,198498,198	$26M	0.86%	ADD 60%
28	RICE HALL JAMES & ASSOCIATES, LLC	477,416477,416	$25M	0.82%	ADD 2%
29	Woodline Partners LP	448,996448,996	$23M	0.77%	NEW
30	Pictet Asset Management Holding SA	450,764450,764	$22M	0.78%	TRIM -7%
31	Invesco Ltd.	412,683412,683	$21M	0.71%	ADD 4%
32	SG Americas Securities, LLC	377,213377,213	$19M	0.65%	ADD 2847%
33	SYSTEMATIC FINANCIAL MANAGEMENT LP	376,079376,079	$19M	0.65%	ADD 24%
34	VANGUARD FIDUCIARY TRUST CO	369,247369,247	$19M	0.64%	NEW
35	Bank of New York Mellon Corp	362,408362,408	$19M	0.62%	TRIM -2%
36	PRINCIPAL FINANCIAL GROUP INC	341,117341,117	$18M	0.59%	ADD 5%
37	MetLife Investment Management, LLC	304,172304,172	$16M	0.52%	—
38	Krensavage Asset Management, LLC	280,681280,681	$15M	0.48%	TRIM -10%
39	Aberdeen Group plc	275,561275,561	$14M	0.47%	—
40	TWO SIGMA INVESTMENTS, LP	271,228271,228	$14M	0.47%	ADD 125%
41	JPMORGAN CHASE & CO	250,735250,735	$12M	0.43%	—
42	ROYCE & ASSOCIATES LP	229,939229,939	$12M	0.40%	ADD 16%
43	GLENMEDE TRUST CO NA	219,099219,099	$11M	0.38%	TRIM -8%
44	Nuveen, LLC	216,047216,047	$11M	0.37%	ADD 95%
45	FMR LLC	209,370209,370	$11M	0.36%	ADD 68%
46	UBS Group AG	209,124209,124	$11M	0.36%	ADD 386%
47	Public Sector Pension Investment Board	205,158205,158	$11M	0.35%	ADD 3%
48	Aristotle Capital Boston, LLC	203,094203,094	$11M	0.35%	TRIM -13%
49	ExodusPoint Capital Management, LP	202,116202,116	$10M	0.35%	TRIM -12%
50	AMERIPRISE FINANCIAL INC	173,905173,905	$9M	0.30%	TRIM -4%
51	RHUMBLINE ADVISERS	169,275169,275	$9M	0.29%	ADD 3%
52	SCHRODER INVESTMENT MANAGEMENT GROUP	176,076176,076	$9M	0.30%	TRIM -7%
53	AXIOM INVESTORS LLC /DE	163,978163,978	$8M	0.28%	ADD 54%
54	SEI INVESTMENTS CO	162,406162,406	$8M	0.28%	ADD 5%
55	AMERICAN CENTURY COMPANIES INC	161,025161,025	$8M	0.28%	TRIM -3%
56	THIRD AVENUE MANAGEMENT LLC	152,724152,724	$8M	0.26%	TRIM -19%
57	Susquehanna Portfolio Strategies, LLC	142,182142,182	$7M	0.24%	—
58	Legal & General Group Plc	135,810135,810	$7M	0.23%	TRIM -6%
59	TEACHER RETIREMENT SYSTEM OF TEXAS	130,034130,034	$7M	0.22%	—
60	RAYMOND JAMES FINANCIAL INC	125,293125,293	$6M	0.22%	ADD 41%
61	DEUTSCHE BANK AG\	118,550118,550	$6M	0.20%	ADD 5%
62	Swiss National Bank	113,500113,500	$6M	0.20%	ADD 3%
63	BARCLAYS PLC	109,114109,114	$6M	0.19%	—
64	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	107,856107,856	$6M	0.19%	ADD 7%
65	Bruce & Co., Inc.	100,000100,000	$5M	0.17%	ADD 22%
66	AQR CAPITAL MANAGEMENT LLC	98,25798,257	$5M	0.17%	TRIM -22%
67	Hudson Bay Capital Management LP	90,82190,821	$5M	0.16%	NEW
68	Hennion & Walsh Asset Management, Inc.	88,45488,454	$5M	0.15%	ADD 10%
69	FRANKLIN RESOURCES INC	85,95685,956	$4M	0.15%	TRIM -6%
70	NATIXIS	85,20085,200	$4M	0.15%	NEW
71	Parkman Healthcare Partners LLC	85,06285,062	$4M	0.15%	NEW
72	NEW YORK STATE TEACHERS RETIREMENT SYSTEM	78,07278,072	$4M	0.13%	TRIM -2%
73	PDT Partners, LLC	76,67376,673	$4M	0.13%	—
74	CITIGROUP INC	75,11875,118	$4M	0.13%	ADD 141%
75	Man Group plc	74,99274,992	$4M	0.13%	ADD 141%
76	Universal- Beteiligungs- und Servicegesellschaft mbH	72,43072,430	$4M	0.12%	TRIM -10%
77	WEDGE CAPITAL MANAGEMENT L L P/NC	69,64369,643	$4M	0.12%	TRIM -11%
78	SIT INVESTMENT ASSOCIATES INC	68,82568,825	$4M	0.12%	ADD 6%
79	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	67,68667,686	$3M	0.12%	ADD 27%
80	MARTINGALE ASSET MANAGEMENT L P	67,54867,548	$3M	0.12%	ADD 16%
81	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	66,00066,000	$3M	0.11%	NEW
82	Phocas Financial Corp.	63,41363,413	$3M	0.11%	TRIM -22%
83	PRICE T ROWE ASSOCIATES INC /MD/	63,38563,385	$3M	0.11%	ADD 20%
84	STATE OF WISCONSIN INVESTMENT BOARD	63,38363,383	$3M	0.11%	—
85	Bridge City Capital, LLC	62,92362,923	$3M	0.11%	—
86	PRUDENTIAL FINANCIAL INC	62,87562,875	$3M	0.11%	TRIM -14%
87	Catalio Capital Management, LP	62,01962,019	$3M	0.11%	TRIM -76%
88	BNP PARIBAS FINANCIAL MARKETS	61,98361,983	$3M	0.11%	TRIM -20%
89	STIFEL FINANCIAL CORP	60,53960,539	$3M	0.10%	ADD 20%
90	Russell Investments Group, Ltd.	57,77657,776	$3M	0.10%	TRIM -34%
91	JANE STREET GROUP, LLC	57,32757,327	$3M	0.10%	ADD 57%
92	ALLIANCEBERNSTEIN L.P.	55,93755,937	$3M	0.10%	ADD 3%
93	DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	52,80952,809	$3M	0.09%	ADD 377%
94	NFJ INVESTMENT GROUP, LLC	52,79052,790	$3M	0.09%	NEW
95	S&T Bank/PA	52,48552,485	$3M	0.09%	TRIM -30%
96	VELA Investment Management, LLC	51,61151,611	$3M	0.09%	ADD 3%
97	VANGUARD ASSET MANAGEMENT, Ltd	50,47650,476	$3M	0.09%	NEW
98	CANADA LIFE ASSURANCE Co	49,00749,007	$3M	0.08%	—
99	Schonfeld Strategic Advisors LLC	48,76548,765	$3M	0.08%	NEW
100	GREAT LAKES ADVISORS, LLC	48,18048,180	$2M	0.08%	TRIM -8%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

10.0M

9.7M

9.4M

8.7M

8.8M

$455M

MILLENNIUM MANAGEMENT LLC

30K

143K

13K

346K

2.6M

3.3M

$171M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

3.2M

$167M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.5M

$128M

DIMENSIONAL FUND ADVISORS LP

2.9M

3.0M

2.7M

2.3M

$119M

STATE STREET CORP

2.2M

2.1M

2.2M

2.3M

$118M

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

—

2.3M

2.0M

$105M

ARMISTICE CAPITAL, LLC

4.8M

5.2M

4.8M

2.8M

1.9M

$98M

RENAISSANCE TECHNOLOGIES LLC

1.6M

1.7M

$88M

GEODE CAPITAL MANAGEMENT, LLC

1.5M

1.3M

1.4M

1.5M

1.6M

$84M

CITADEL ADVISORS LLC

94K

162K

175K

1.4M

453K

1.5M

$77M

LOOMIS SAYLES & CO L P

1.5M

1.4M

1.3M

1.4M

$74M

Stephens Investment Management Group LLC

1.8M

1.7M

1.6M

1.3M

1.4M

$70M

Point72 Asset Management, L.P.

27K

319K

508K

1.8M

2.3M

1.3M

$68M

GW&K Investment Management, LLC

1.2M

1.4M

1.3M

1.1M

$55M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	325	58,220,249	100.3%	$3.0B
2025-Q4

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · SUPN

Large holders — 13G, passive (top 5 of 7 by % of class)

Holder

% of class

Type

As of

BlackRock, Inc.

14.7%

QII

2025-03-31

SEC →

MILLENNIUM MANAGEMENT LLC

5.7%

Passive

2026-02-11

SEC →

VANGUARD PORTFOLIO MANAGEMENT LLC

5.66%

QII

2026-03-31

SEC →

VANGUARD CAPITAL MANAGEMENT LLC

5.03%

QII

2026-03-31

SEC →

ARMISTICE CAPITAL, LLC

4.82%

QII

Institutional ownership· 13F filers holding SUPN · 2026-Q1 methodology → sources →

325 holders

% of shares outstanding held

100.3%

Shares held (13F)

58,220,249

Reporting holders

325

Top holders

largest 100 of 325 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	8,797,2548.8M	$455M	15.16%	—
2	MILLENNIUM MANAGEMENT LLC	3,315,9733.3M	$171M	5.71%	ADD 26%
3	VANGUARD PORTFOLIO MANAGEMENT LLC	3,238,6933.2M	$167M	5.58%	NEW†
4	VANGUARD CAPITAL MANAGEMENT LLC	2,467,2152.5M	$128M	4.25%	NEW†
5	DIMENSIONAL FUND ADVISORS LP	2,307,0302.3M	$119M	3.97%	TRIM -15%
6	STATE STREET CORP	2,288,1272.3M	$118M	3.94%	ADD 3%
7	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	2,037,2022.0M	$105M	3.51%	TRIM -12%
8	ARMISTICE CAPITAL, LLC	1,895,3471.9M	$98M	3.27%	TRIM -31%
9	RENAISSANCE TECHNOLOGIES LLC	1,705,2221.7M	$88M	2.94%	—
10	GEODE CAPITAL MANAGEMENT, LLC	1,623,5141.6M	$84M	2.80%	ADD 10%
11	CITADEL ADVISORS LLC	1,493,4461.5M	$77M	2.57%	ADD 230%
12	LOOMIS SAYLES & CO L P	1,425,7791.4M	$74M	2.46%	—
13	Stephens Investment Management Group LLC	1,351,3311.4M	$70M	2.33%	TRIM -4%
14	Point72 Asset Management, L.P.	1,318,5551.3M	$68M	2.27%	TRIM -42%
15	GW&K Investment Management, LLC	1,055,1841.1M	$55M	1.82%	TRIM -2%
16	Sofinnova Investments, Inc.	954,309954,309	$49M	1.64%	ADD 73%
17	MORGAN STANLEY	913,893913,893	$47M	1.57%	TRIM -15%
18	GOLDMAN SACHS GROUP INC	856,487856,487	$44M	1.48%	ADD 30%
19	BANK OF AMERICA CORP /DE/	714,226714,226	$37M	1.23%	ADD 37%
20	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	705,976705,976	$36M	1.22%	—
21	NORTHERN TRUST CORP	699,456699,456	$36M	1.21%	ADD 4%
22	ASHFORD CAPITAL MANAGEMENT INC	645,381645,381	$33M	1.11%	ADD 5%
23	Freestone Grove Partners LP	641,319641,319	$33M	1.10%	ADD 227%
24	D. E. Shaw & Co., Inc.	622,450622,450	$32M	1.07%	TRIM -12%
25	Assenagon Asset Management S.A.	530,618530,618	$27M	0.91%	NEW
26	VICTORY CAPITAL MANAGEMENT INC	502,406502,406	$26M	0.87%	TRIM -5%
27	Qube Research & Technologies Ltd	498,198498,198	$26M	0.86%	ADD 60%
28	RICE HALL JAMES & ASSOCIATES, LLC	477,416477,416	$25M	0.82%	ADD 2%
29	Woodline Partners LP	448,996448,996	$23M	0.77%	NEW
30	Pictet Asset Management Holding SA	450,764450,764	$22M	0.78%	TRIM -7%
31	Invesco Ltd.	412,683412,683	$21M	0.71%	ADD 4%
32	SG Americas Securities, LLC	377,213377,213	$19M	0.65%	ADD 2847%
33	SYSTEMATIC FINANCIAL MANAGEMENT LP	376,079376,079	$19M	0.65%	ADD 24%
34	VANGUARD FIDUCIARY TRUST CO	369,247369,247	$19M	0.64%	NEW
35	Bank of New York Mellon Corp	362,408362,408	$19M	0.62%	TRIM -2%
36	PRINCIPAL FINANCIAL GROUP INC	341,117341,117	$18M	0.59%	ADD 5%
37	MetLife Investment Management, LLC	304,172304,172	$16M	0.52%	—
38	Krensavage Asset Management, LLC	280,681280,681	$15M	0.48%	TRIM -10%
39	Aberdeen Group plc	275,561275,561	$14M	0.47%	—
40	TWO SIGMA INVESTMENTS, LP	271,228271,228	$14M	0.47%	ADD 125%
41	JPMORGAN CHASE & CO	250,735250,735	$12M	0.43%	—
42	ROYCE & ASSOCIATES LP	229,939229,939	$12M	0.40%	ADD 16%
43	GLENMEDE TRUST CO NA	219,099219,099	$11M	0.38%	TRIM -8%
44	Nuveen, LLC	216,047216,047	$11M	0.37%	ADD 95%
45	FMR LLC	209,370209,370	$11M	0.36%	ADD 68%
46	UBS Group AG	209,124209,124	$11M	0.36%	ADD 386%
47	Public Sector Pension Investment Board	205,158205,158	$11M	0.35%	ADD 3%
48	Aristotle Capital Boston, LLC	203,094203,094	$11M	0.35%	TRIM -13%
49	ExodusPoint Capital Management, LP	202,116202,116	$10M	0.35%	TRIM -12%
50	AMERIPRISE FINANCIAL INC	173,905173,905	$9M	0.30%	TRIM -4%
51	RHUMBLINE ADVISERS	169,275169,275	$9M	0.29%	ADD 3%
52	SCHRODER INVESTMENT MANAGEMENT GROUP	176,076176,076	$9M	0.30%	TRIM -7%
53	AXIOM INVESTORS LLC /DE	163,978163,978	$8M	0.28%	ADD 54%
54	SEI INVESTMENTS CO	162,406162,406	$8M	0.28%	ADD 5%
55	AMERICAN CENTURY COMPANIES INC	161,025161,025	$8M	0.28%	TRIM -3%
56	THIRD AVENUE MANAGEMENT LLC	152,724152,724	$8M	0.26%	TRIM -19%
57	Susquehanna Portfolio Strategies, LLC	142,182142,182	$7M	0.24%	—
58	Legal & General Group Plc	135,810135,810	$7M	0.23%	TRIM -6%
59	TEACHER RETIREMENT SYSTEM OF TEXAS	130,034130,034	$7M	0.22%	—
60	RAYMOND JAMES FINANCIAL INC	125,293125,293	$6M	0.22%	ADD 41%
61	DEUTSCHE BANK AG\	118,550118,550	$6M	0.20%	ADD 5%
62	Swiss National Bank	113,500113,500	$6M	0.20%	ADD 3%
63	BARCLAYS PLC	109,114109,114	$6M	0.19%	—
64	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	107,856107,856	$6M	0.19%	ADD 7%
65	Bruce & Co., Inc.	100,000100,000	$5M	0.17%	ADD 22%
66	AQR CAPITAL MANAGEMENT LLC	98,25798,257	$5M	0.17%	TRIM -22%
67	Hudson Bay Capital Management LP	90,82190,821	$5M	0.16%	NEW
68	Hennion & Walsh Asset Management, Inc.	88,45488,454	$5M	0.15%	ADD 10%
69	FRANKLIN RESOURCES INC	85,95685,956	$4M	0.15%	TRIM -6%
70	NATIXIS	85,20085,200	$4M	0.15%	NEW
71	Parkman Healthcare Partners LLC	85,06285,062	$4M	0.15%	NEW
72	NEW YORK STATE TEACHERS RETIREMENT SYSTEM	78,07278,072	$4M	0.13%	TRIM -2%
73	PDT Partners, LLC	76,67376,673	$4M	0.13%	—
74	CITIGROUP INC	75,11875,118	$4M	0.13%	ADD 141%
75	Man Group plc	74,99274,992	$4M	0.13%	ADD 141%
76	Universal- Beteiligungs- und Servicegesellschaft mbH	72,43072,430	$4M	0.12%	TRIM -10%
77	WEDGE CAPITAL MANAGEMENT L L P/NC	69,64369,643	$4M	0.12%	TRIM -11%
78	SIT INVESTMENT ASSOCIATES INC	68,82568,825	$4M	0.12%	ADD 6%
79	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	67,68667,686	$3M	0.12%	ADD 27%
80	MARTINGALE ASSET MANAGEMENT L P	67,54867,548	$3M	0.12%	ADD 16%
81	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	66,00066,000	$3M	0.11%	NEW
82	Phocas Financial Corp.	63,41363,413	$3M	0.11%	TRIM -22%
83	PRICE T ROWE ASSOCIATES INC /MD/	63,38563,385	$3M	0.11%	ADD 20%
84	STATE OF WISCONSIN INVESTMENT BOARD	63,38363,383	$3M	0.11%	—
85	Bridge City Capital, LLC	62,92362,923	$3M	0.11%	—
86	PRUDENTIAL FINANCIAL INC	62,87562,875	$3M	0.11%	TRIM -14%
87	Catalio Capital Management, LP	62,01962,019	$3M	0.11%	TRIM -76%
88	BNP PARIBAS FINANCIAL MARKETS	61,98361,983	$3M	0.11%	TRIM -20%
89	STIFEL FINANCIAL CORP	60,53960,539	$3M	0.10%	ADD 20%
90	Russell Investments Group, Ltd.	57,77657,776	$3M	0.10%	TRIM -34%
91	JANE STREET GROUP, LLC	57,32757,327	$3M	0.10%	ADD 57%
92	ALLIANCEBERNSTEIN L.P.	55,93755,937	$3M	0.10%	ADD 3%
93	DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	52,80952,809	$3M	0.09%	ADD 377%
94	NFJ INVESTMENT GROUP, LLC	52,79052,790	$3M	0.09%	NEW
95	S&T Bank/PA	52,48552,485	$3M	0.09%	TRIM -30%
96	VELA Investment Management, LLC	51,61151,611	$3M	0.09%	ADD 3%
97	VANGUARD ASSET MANAGEMENT, Ltd	50,47650,476	$3M	0.09%	NEW
98	CANADA LIFE ASSURANCE Co	49,00749,007	$3M	0.08%	—
99	Schonfeld Strategic Advisors LLC	48,76548,765	$3M	0.08%	NEW
100	GREAT LAKES ADVISORS, LLC	48,18048,180	$2M	0.08%	TRIM -8%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

10.0M

9.7M

9.4M

8.7M

8.8M

$455M

MILLENNIUM MANAGEMENT LLC

30K

143K

13K

346K

2.6M

3.3M

$171M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

3.2M

$167M

VANGUARD CAPITAL MANAGEMENT LLC

—

2.5M

$128M

DIMENSIONAL FUND ADVISORS LP

2.9M

3.0M

2.7M

2.3M

$119M

STATE STREET CORP

2.2M

2.1M

2.2M

2.3M

$118M

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

—

2.3M

2.0M

$105M

ARMISTICE CAPITAL, LLC

4.8M

5.2M

4.8M

2.8M

1.9M

$98M

RENAISSANCE TECHNOLOGIES LLC

1.6M

1.7M

$88M

GEODE CAPITAL MANAGEMENT, LLC

1.5M

1.3M

1.4M

1.5M

1.6M

$84M

CITADEL ADVISORS LLC

94K

162K

175K

1.4M

453K

1.5M

$77M

LOOMIS SAYLES & CO L P

1.5M

1.4M

1.3M

1.4M

$74M

Stephens Investment Management Group LLC

1.8M

1.7M

1.6M

1.3M

1.4M

$70M

Point72 Asset Management, L.P.

27K

319K

508K

1.8M

2.3M

1.3M

$68M

GW&K Investment Management, LLC

1.2M

1.4M

1.3M

1.1M

$55M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	325	58,220,249	100.3%	$3.0B
2025-Q4

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · SUPN

Large holders — 13G, passive (top 5 of 7 by % of class)

Holder

% of class

Type

As of

BlackRock, Inc.

14.7%

QII

2025-03-31

SEC →

MILLENNIUM MANAGEMENT LLC

5.7%

Passive

2026-02-11

SEC →

VANGUARD PORTFOLIO MANAGEMENT LLC

5.66%

QII

2026-03-31

SEC →

VANGUARD CAPITAL MANAGEMENT LLC

5.03%

QII

2026-03-31

SEC →

ARMISTICE CAPITAL, LLC

4.82%

QII

SUPN US Equity☆

Institutional ownership· 13F filers holding SUPN · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · SUPN

Institutional ownership· 13F filers holding SUPN · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · SUPN

SUPN US Equity