Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-15 | Parker Craig C | Director,Officer | +Grant | 1,622 | $8.11 | $13,154 |
| 2026-06-15 | Williams Charles O | Officer | +Grant | 1,666 | $8.11 | $13,511 |
| 2026-06-15 | Li Yang | Officer | +Grant | 1,666 | $8.11 | $13,511 |
| 2026-06-15 | Maleki Andrew Pedrum | Officer | +Grant | 607 | $19.01 | $11,539 |
| 2026-05-04 | Parker Craig C | Director,Officer | −Sell | 4,524 | $33.33 | $150,785 |
| 2026-05-04 | Williams Charles O | Officer | −Sell | 2,036 | $33.33 | $67,860 |
| 2026-05-04 | Li Yang | Officer | −Sell | 1,584 | $33.33 | $52,795 |
| 2026-05-01 | Parker Craig C | Director,Officer | +Exercise | 12,500 | — | — |
| 2026-05-01 | Williams Charles O | Officer | +Exercise | 5,625 | — | — |
| 2026-05-01 | Li Yang | Officer | +Exercise | 4,375 | — | — |
| 2026-03-31 | Li Yang | Officer | −Gift | 1,666 | — | — |
| 2026-03-24 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 53,329 | $24.69 | $1M |
| 2026-03-24 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 53,329 | $24.69 | $1M |
| 2026-03-23 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 7,611 | $24.90 | $189,514 |
| 2026-03-23 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 7,612 | $24.90 | $189,539 |
| 2026-03-16 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 595 | $24.99 | $14,869 |
| 2026-03-16 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 595 | $24.99 | $14,869 |
| 2026-03-13 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 17,716 | $24.88 | $440,774 |
| 2026-03-13 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 17,717 | $24.88 | $440,799 |
| 2026-03-12 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 6,187 | $24.99 | $154,613 |
| 2026-03-12 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 6,187 | $24.99 | $154,613 |
| 2026-02-12 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 547 | $23.86 | $13,051 |
| 2026-02-12 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 546 | $23.86 | $13,028 |
| 2026-02-11 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 8,881 | $23.58 | $209,414 |
| 2026-02-11 | TCG Crossover Fund II, L.P. | TenPercentOwner | +Buy | 8,882 | $23.58 | $209,438 |
| 2026-02-03 | TCG Crossover GP III, LLC | TenPercentOwner | +Buy | 2,177 | $21.94 | $47,763 |
| 2026-02-03 | TCG Crossover GP III, LLC | TenPercentOwner | +Buy | 2,178 | $21.94 | $47,785 |
| 2026-02-02 | TCG Crossover GP III, LLC | TenPercentOwner | +Buy | 365 | $21.38 | $7,804 |
| 2026-02-02 | TCG Crossover GP III, LLC | TenPercentOwner | +Buy | 366 | $21.38 | $7,825 |
| 2026-01-30 | TCG Crossover GP III, LLC | TenPercentOwner | +Buy | 2,135 | $21.39 | $45,668 |
| 2026-01-30 | TCG Crossover GP III, LLC | TenPercentOwner | +Buy | 2,136 | $21.39 | $45,689 |
| 2026-01-20 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 8,484 | $19.60 | $166,286 |
| 2026-01-20 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 9,568 | $19.60 | $187,533 |
| 2026-01-20 | Column Group Opportunity III GP, LP | TenPercentOwner | +Buy | 8,484 | $19.60 | $166,286 |
| 2026-01-20 | Column Group Opportunity III GP, LP | TenPercentOwner | +Buy | 9,568 | $19.60 | $187,533 |
| 2026-01-16 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 1,204 | $20.00 | $24,080 |
| 2026-01-16 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 1,358 | $20.00 | $27,160 |
| 2026-01-16 | Column Group Opportunity III GP, LP | TenPercentOwner | +Buy | 1,204 | $20.00 | $24,080 |
| 2026-01-16 | Column Group Opportunity III GP, LP | TenPercentOwner | +Buy | 1,358 | $20.00 | $27,160 |
| 2026-01-15 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 6,303 | $19.89 | $125,367 |
| 2026-01-15 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 5,590 | $19.89 | $111,185 |
| 2026-01-15 | Column Group Opportunity III GP, LP | TenPercentOwner | +Buy | 6,303 | $19.89 | $125,367 |
| 2026-01-15 | Column Group Opportunity III GP, LP | TenPercentOwner | +Buy | 5,590 | $19.89 | $111,185 |
| 2026-01-14 | TCG Opportunity III GP, LLC | TenPercentOwner | +Buy | 2,596 | $19.99 | $51,894 |
| 2026-01-14 | TCG Opportunity III GP, LLC | TenPercentOwner | +Buy | 2,927 | $19.99 | $58,511 |
| 2026-01-14 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 2,596 | $19.99 | $51,894 |
| 2026-01-14 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 2,927 | $19.99 | $58,511 |
| 2026-01-13 | TCG Opportunity III GP, LLC | TenPercentOwner | +Buy | 6,609 | $19.80 | $130,858 |
| 2026-01-13 | TCG Opportunity III GP, LLC | TenPercentOwner | +Buy | 5,861 | $19.80 | $116,048 |
| 2026-01-13 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 6,609 | $19.80 | $130,858 |
| 2026-01-13 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 5,861 | $19.80 | $116,048 |
| 2026-01-06 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 7,097 | $19.89 | $141,159 |
| 2026-01-06 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 8,003 | $19.89 | $159,180 |
| 2026-01-06 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 8,003 | $19.89 | $159,180 |
| 2026-01-06 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 7,097 | $19.89 | $141,159 |
| 2026-01-05 | Williams Charles O | Officer | −Sell | 1,566 | $19.87 | $31,116 |
| 2026-01-05 | Li Yang | Officer | −Sell | 1,118 | $19.87 | $22,215 |
| 2026-01-02 | Williams Charles O | Officer | +Exercise | 3,500 | — | — |
| 2026-01-02 | Li Yang | Officer | +Exercise | 2,500 | — | — |
| 2025-12-15 | Parker Craig C | Director,Officer | +Grant | 1,553 | $8.11 | $12,595 |
| 2025-12-15 | Williams Charles O | Officer | +Grant | 1,666 | $8.11 | $13,511 |
| 2025-12-15 | Li Yang | Officer | +Grant | 1,666 | $8.11 | $13,511 |
| 2025-12-05 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 16,381 | $19.54 | $320,085 |
| 2025-12-05 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 14,503 | $19.54 | $283,389 |
| 2025-12-05 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 14,503 | $19.54 | $283,389 |
| 2025-12-05 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 16,381 | $19.54 | $320,085 |
| 2025-12-04 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 2,791 | $17.35 | $48,424 |
| 2025-12-04 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 2,475 | $17.35 | $42,941 |
| 2025-12-04 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 2,475 | $17.35 | $42,941 |
| 2025-12-04 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 2,791 | $17.35 | $48,424 |
| 2025-11-13 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 148,150 | $12.65 | $2M |
| 2025-11-13 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 167,307 | $12.65 | $2M |
| 2025-11-13 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 148,150 | $12.65 | $2M |
| 2025-11-13 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 167,307 | $12.65 | $2M |
| 2025-06-13 | Parker Craig C | Director,Officer | +Grant | 400 | $8.06 | $3,224 |
| 2025-06-13 | Williams Charles O | Officer | +Grant | 400 | $8.06 | $3,224 |
| 2025-06-13 | Li Yang | Officer | +Grant | 400 | $8.06 | $3,224 |
| 2025-03-26 | Column Group Opportunity III, LP | TenPercentOwner | +Buy | 323,886 | $11.60 | $4M |
| 2025-03-26 | Column Group Opportunity III, LP | TenPercentOwner | +Buy | 365,769 | $11.60 | $4M |
| 2025-03-26 | Column Group Opportunity III, LP | TenPercentOwner | +Buy | 344,827 | $11.60 | $4M |
| 2025-01-03 | Williams Charles O | Officer | −Sell | 1,181 | $17.37 | $20,514 |
| 2025-01-03 | Li Yang | Officer | −Sell | 843 | $17.37 | $14,643 |
| 2025-01-02 | Williams Charles O | Officer | +Exercise | 3,500 | — | — |
| 2025-01-02 | Li Yang | Officer | +Exercise | 2,500 | — | — |
| 2024-06-14 | Parker Craig C | Director,Officer | +Grant | 400 | $5.67 | $2,268 |
| 2024-06-14 | Williams Charles O | Officer | +Grant | 400 | $5.67 | $2,268 |
| 2024-06-14 | Li Yang | Officer | +Grant | 400 | $5.67 | $2,268 |
| 2024-04-04 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 90,897 | $15.50 | $1M |
| 2024-04-04 | COLUMN GROUP III GP, LP | TenPercentOwner | +Buy | 102,651 | $15.50 | $2M |
| 2024-04-04 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 90,897 | $15.50 | $1M |
| 2024-04-04 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 102,651 | $15.50 | $2M |
| 2024-04-04 | Parker Craig C | Director,Officer | +Buy | 1,474 | — | — |
| 2024-04-04 | Williams Charles O | Officer | +Buy | 1,474 | — | — |
| 2024-04-04 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 102,651 | $15.50 | $2M |
| 2024-04-04 | Kutzkey Tim | Director,TenPercentOwner | +Buy | 90,897 | $15.50 | $1M |
| 2024-04-04 | COLUMN GROUP III-A, LP | TenPercentOwner | +Buy | 102,651 | $15.50 | $2M |
| 2024-04-04 | COLUMN GROUP III-A, LP | TenPercentOwner | +Buy | 90,897 | $15.50 | $1M |
| 2023-12-15 | Parker Craig C | Director,Officer | +Grant | 2,046 | $5.67 | $11,601 |
| 2023-12-15 | Li Yang | Officer | +Grant | 2,085 | $5.67 | $11,822 |
| 2023-12-15 | Williams Charles O | Officer | +Grant | 2,085 | $5.67 | $11,822 |
| 2023-06-15 | Williams Charles O | Officer | +Grant | 25,000 | $0.38 | $9,500 |
| 2023-06-15 | Yeh Wen-Chen | Officer | +Grant | 17,638 | $0.38 | $6,702 |
| 2023-06-15 | Parker Craig C | Director,Officer | +Grant | 25,000 | $0.38 | $9,500 |
| 2022-12-15 | Williams Charles O | Officer | +Grant | 9,578 | $0.41 | $3,927 |
| 2022-12-15 | Vanhove Geertrui | Officer | +Grant | 9,578 | $0.41 | $3,927 |
| 2022-12-15 | Parker Craig C | Director,Officer | +Grant | 9,578 | $0.41 | $3,927 |
| 2022-12-15 | Yeh Wen-Chen | Officer | +Grant | 9,578 | $0.41 | $3,927 |
| 2022-12-14 | Soffer Benny | TenPercentOwner | −Sell | 1,297,922 | — | — |
| 2022-12-14 | Soffer Benny | TenPercentOwner | −Sell | 450,827 | — | — |
| 2022-12-14 | Soffer Benny | TenPercentOwner | −Sell | 1,885,000 | — | — |
| 2022-12-14 | Soffer Benny | TenPercentOwner | −Sell | 1,748,750 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | −Disp→issuer | 500,000 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | +Grant | 500,000 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | −Disp→issuer | 371,100 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | −Disp→issuer | 128,900 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | +Grant | 128,900 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | +Grant | 1,248,750 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | +Grant | 926,822 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | +Grant | 321,928 | — | — |
| 2021-08-11 | Consonance Capman GP, LLC | TenPercentOwner | +Grant | 371,100 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
