PRME US Equity

Prime Medicine, Inc.

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Health Care · Biological Products, (No Diagnostic Substances) · CIK 1894562 · FYE 1231

$3.09

+0.08 (+2.66%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding PRME · 2026-Q1 methodology → sources →

190 holders

% of shares outstanding held

54.4%

Shares held (13F)

98,329,186

Reporting holders

190

Top holders

largest 100 of 190 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Alphabet Inc.	16,562,49816.6M	$58M	9.17%	—
2	BlackRock, Inc.	8,501,7088.5M	$30M	4.71%	ADD 3%
3	STATE STREET CORP	6,345,1256.3M	$22M	3.51%	ADD 25%
4	ARK Investment Management LLC	6,246,8276.2M	$22M	3.46%	ADD 16%
5	T. Rowe Price Investment Management, Inc.	5,481,8935.5M	$19M	3.04%	TRIM -23%
6	VANGUARD CAPITAL MANAGEMENT LLC	4,474,1624.5M	$16M	2.48%	NEW†
7	Balyasny Asset Management L.P.	4,123,3654.1M	$14M	2.28%	ADD 32%
8	Casdin Capital, LLC	3,167,1753.2M	$11M	1.75%	—
9	Woodline Partners LP	3,003,3133.0M	$10M	1.66%	—
10	Sumitomo Mitsui Trust Group, Inc.	2,940,7932.9M	$10M	1.63%	TRIM -9%
11	Amova Asset Management Americas, Inc.	2,940,7932.9M	$10M	1.63%	TRIM -9%
12	UBS Group AG	2,888,4182.9M	$10M	1.60%	ADD 18%
13	GEODE CAPITAL MANAGEMENT, LLC	2,743,7002.7M	$10M	1.52%	ADD 4%
14	ADAR1 Capital Management, LLC	1,973,2822.0M	$7M	1.09%	NEW
15	FMR LLC	1,769,4761.8M	$6M	0.98%	TRIM -19%
16	Redmile Group, LLC	1,590,8321.6M	$6M	0.88%	NEW
17	TWO SIGMA INVESTMENTS, LP	1,572,8111.6M	$5M	0.87%	TRIM -3%
18	D. E. Shaw & Co., Inc.	1,393,6211.4M	$5M	0.77%	TRIM -10%
19	FARALLON CAPITAL MANAGEMENT LLC	1,240,8431.2M	$4M	0.69%	—
20	GOLDMAN SACHS GROUP INC	970,425970,425	$3M	0.54%	TRIM -45%
21	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	917,212917,212	$3M	0.51%	TRIM -2%
22	NORTHERN TRUST CORP	886,716886,716	$3M	0.49%	ADD 5%
23	VANGUARD PORTFOLIO MANAGEMENT LLC	862,204862,204	$3M	0.48%	NEW
24	JPMORGAN CHASE & CO	844,154844,154	$3M	0.47%	ADD 94%
25	Greenwich Wealth Management LLC	750,001750,001	$3M	0.42%	—
26	RENAISSANCE TECHNOLOGIES LLC	741,039741,039	$3M	0.41%	TRIM -36%
27	VANGUARD FIDUCIARY TRUST CO	717,002717,002	$2M	0.40%	NEW
28	SUSQUEHANNA INTERNATIONAL GROUP, LLP	715,829715,829	$2M	0.40%	TRIM -39%
29	MORGAN STANLEY	639,457639,457	$2M	0.35%	TRIM -45%
30	HRT FINANCIAL LP	612,769612,769	$2M	0.34%	TRIM -6%
31	BANK OF AMERICA CORP /DE/	577,004577,004	$2M	0.32%	TRIM -11%
32	AQR CAPITAL MANAGEMENT LLC	554,935554,935	$2M	0.31%	ADD 33%
33	MOORE CAPITAL MANAGEMENT, LP	500,000500,000	$2M	0.28%	—
34	Alessandra Capital Management, LLC	425,510425,510	$1M	0.24%	NEW
35	Bollard Group LLC	361,136361,136	$1M	0.20%	—
36	HighTower Advisors, LLC	340,255340,255	$1M	0.19%	TRIM -15%
37	CITADEL ADVISORS LLC	336,358336,358	$1M	0.19%	ADD 198%
38	WELLS FARGO & COMPANY/MN	319,550319,550	$1M	0.18%	ADD 9%
39	DIMENSIONAL FUND ADVISORS LP	304,522304,522	$1M	0.17%	ADD 262%
40	WELLINGTON MANAGEMENT GROUP LLP	278,120278,120	$967,857	0.15%	ADD 12%
41	Nuveen, LLC	275,931275,931	$960,240	0.15%	ADD 10%
42	Bank of New York Mellon Corp	267,219267,219	$929,922	0.15%	ADD 8%
43	CHELSEA COUNSEL CO	227,000227,000	$787,690	0.13%	—
44	Rafferty Asset Management, LLC	215,582215,582	$750,225	0.12%	ADD 15%
45	IQ EQ FUND MANAGEMENT (IRELAND) Ltd	205,389205,389	$714,754	0.11%	ADD 15%
46	Green Alpha Advisors, LLC	191,171191,171	$665,275	0.11%	—
47	Swiss National Bank	178,600178,600	$621,528	0.10%	ADD 5%
48	Keystone Financial Group	166,010166,010	$577,715	0.09%	ADD 28%
49	DEUTSCHE BANK AG\	157,440157,440	$547,891	0.09%	ADD 6%
50	XTX Topco Ltd	157,282157,282	$547,341	0.09%	ADD 116%
51	Elevate Capital Advisors, LLC	151,069151,069	$525,720	0.08%	ADD 254%
52	MARSHALL WACE, LLP	141,957141,957	$494,010	0.08%	NEW
53	BRIDGEWAY CAPITAL MANAGEMENT, LLC	134,800134,800	$469,104	0.07%	—
54	PRICE T ROWE ASSOCIATES INC /MD/	133,755133,755	$466,000	0.07%	ADD 28%
55	ALLIANCEBERNSTEIN L.P.	122,460122,460	$424,936	0.07%	ADD 13%
56	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	122,463122,463	$421,223	0.07%	ADD 6%
57	Steward Partners Investment Advisory, LLC	117,456117,456	$408,747	0.07%	—
58	FIL Ltd	115,206115,206	$400,917	0.06%	—
59	RHUMBLINE ADVISERS	114,269114,269	$397,649	0.06%	ADD 5%
60	Engineers Gate Manager LP	110,348110,348	$384,011	0.06%	ADD 82%
61	Palumbo Wealth Management LLC	102,246102,246	$355,817	0.06%	ADD 20%
62	Invesco Ltd.	96,87596,875	$337,125	0.05%	ADD 71%
63	PROFUND ADVISORS LLC	95,80695,806	$333,405	0.05%	ADD 38%
64	TD Asset Management Inc	94,14894,148	$327,635	0.05%	—
65	Squarepoint Ops LLC	94,06694,066	$327,350	0.05%	TRIM -57%
66	Rockefeller Capital Management L.P.	91,40191,401	$318,076	0.05%	TRIM -25%
67	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	86,47386,473	$300,926	0.05%	—
68	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	85,30085,300	$296,844	0.05%	TRIM -14%
69	Mariner, LLC	78,39878,398	$272,737	0.04%	ADD 116%
70	Concurrent Investment Advisors, LLC	74,17774,177	$258,136	0.04%	NEW
71	IEQ CAPITAL, LLC	74,01374,013	$257,565	0.04%	ADD 99%
72	Virtus Investment Advisers, LLC	66,50866,508	$231,448	0.04%	ADD 2%
73	LPL Financial LLC	66,42466,424	$231,156	0.04%	ADD 102%
74	Legal & General Group Plc	66,44466,444	$230,893	0.04%	TRIM -18%
75	Russell Investments Group, Ltd.	64,27364,273	$223,667	0.04%	ADD 841%
76	BARCLAYS PLC	63,77363,773	$221,931	0.04%	TRIM -82%
77	TUDOR INVESTMENT CORP ET AL	61,54661,546	$214,180	0.03%	NEW
78	JANUS HENDERSON GROUP PLC	60,90060,900	$211,628	0.03%	—
79	&PARTNERS	59,47059,470	$206,956	0.03%	—
80	VANGUARD ASSET MANAGEMENT, Ltd	59,02159,021	$205,393	0.03%	NEW
81	Aquatic Capital Management LLC	54,23054,230	$188,720	0.03%	NEW
82	LOS ANGELES CAPITAL MANAGEMENT LLC	52,61552,615	$183,100	0.03%	NEW
83	AMERIPRISE FINANCIAL INC	49,58449,584	$172,553	0.03%	TRIM -8%
84	CITIGROUP INC	47,23247,232	$164,368	0.03%	TRIM -8%
85	Quadrature Capital Ltd	46,89346,893	$163,188	0.03%	TRIM -11%
86	Mutual Advisors, LLC	45,20045,200	$157,296	0.03%	—
87	Vanguard Global Advisers, LLC	44,26944,269	$154,056	0.02%	NEW
88	MetLife Investment Management, LLC	44,20844,208	$153,844	0.02%	TRIM -23%
89	VARCOV Co.	41,96441,964	$146,035	0.02%	NEW
90	IvyRock Asset Management (HK) Ltd	41,80041,800	$145,464	0.02%	—
91	DRW Securities, LLC	40,96440,964	$142,554	0.02%	NEW
92	JONES FINANCIAL COMPANIES LLLP	40,30740,307	$136,238	0.02%	—
93	AXQ CAPITAL, LP	36,74236,742	$127,862	0.02%	ADD 10%
94	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	37,68137,681	$125,101	0.02%	ADD 44%
95	Kingsview Wealth Management, LLC	35,00035,000	$121,800	0.02%	ADD 133%
96	BNP PARIBAS FINANCIAL MARKETS	34,41334,413	$119,757	0.02%	ADD 250%
97	CWM, LLC	33,81133,811	$117,662	0.02%	ADD 33%
98	OPPENHEIMER & CO INC	33,65633,656	$117,123	0.02%	ADD 171%
99	Crestwood Advisors Group, LLC	32,37432,374	$112,661	0.02%	—
100	China Universal Asset Management Co., Ltd.	32,03332,033	$111,475	0.02%	ADD 9%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Alphabet Inc.

15.1M

16.6M

$58M

BlackRock, Inc.

4.5M

4.3M

4.5M

5.7M

8.3M

8.5M

$30M

STATE STREET CORP

1.2M

1.1M

1.2M

1.3M

5.1M

6.3M

$22M

ARK Investment Management LLC

5.2M

3.1M

2.3M

5.5M

5.4M

6.2M

$22M

T. Rowe Price Investment Management, Inc.

4.0M

4.1M

6.5M

9.2M

7.1M

5.5M

$19M

VANGUARD CAPITAL MANAGEMENT LLC

—

4.5M

$16M

Balyasny Asset Management L.P.

16K

—

48K

3.1M

4.1M

$14M

Casdin Capital, LLC

367K

1.6M

3.2M

$11M

Woodline Partners LP

—

3.0M

$10M

Sumitomo Mitsui Trust Group, Inc.

3.1M

2.9M

1.6M

3.6M

3.2M

2.9M

$10M

Amova Asset Management Americas, Inc.

3.1M

2.9M

1.6M

3.6M

3.2M

2.9M

$10M

UBS Group AG

218K

118K

195K

305K

2.4M

2.9M

$10M

GEODE CAPITAL MANAGEMENT, LLC

1.5M

1.8M

2.6M

2.7M

$10M

ADAR1 Capital Management, LLC

—

2.0M

$7M

FMR LLC

3.8M

3.7M

2.8M

2.2M

1.8M

$6M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	190	98,329,186	54.4%	$342M
2025-Q4	182	98,118,134	54.3%	$340M
2025-Q3	167	92,450,333	51.2%	$512M
2025-Q2	121	58,691,493	32.5%	$145M
2025-Q1	125	60,402,565	33.4%	$120M
2024-Q4	131	64,335,699	35.6%	$188M
2024-Q3	116	68,748,481	38.1%	$266M
2024-Q2	122	68,926,823	38.2%	$354M
2024-Q1	115	67,098,214	37.1%	$470M
2023-Q4	105	48,948,639	27.1%	$434M
2023-Q3	83	49,517,455	27.4%	$472M
2023-Q2	79	46,131,808	25.5%	$676M

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · PRME

Activists — 13D, active intent

ARCH Venture Fund XII, L.P.10.4%NEWSCHEDULE 13D/A · Amd 2 · event 2025-08-07SEC →

18,587,036 shares · 12 reporting persons

Large holders — 13G, passive (top 4 by % of class)

Holder

% of class

Type

As of

GV 2019, L.P.

12.3%

Passive

2025-09-30

SEC →

Newpath Partners, L.P.

4.7%

Exempt

2024-12-31

SEC →

FMR LLC

3.8%

Passive

2025-09-30

SEC →

T. Rowe Price Investment Management, Inc.

Institutional ownership· 13F filers holding PRME · 2026-Q1 methodology → sources →

190 holders

% of shares outstanding held

54.4%

Shares held (13F)

98,329,186

Reporting holders

190

Top holders

largest 100 of 190 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Alphabet Inc.	16,562,49816.6M	$58M	9.17%	—
2	BlackRock, Inc.	8,501,7088.5M	$30M	4.71%	ADD 3%
3	STATE STREET CORP	6,345,1256.3M	$22M	3.51%	ADD 25%
4	ARK Investment Management LLC	6,246,8276.2M	$22M	3.46%	ADD 16%
5	T. Rowe Price Investment Management, Inc.	5,481,8935.5M	$19M	3.04%	TRIM -23%
6	VANGUARD CAPITAL MANAGEMENT LLC	4,474,1624.5M	$16M	2.48%	NEW†
7	Balyasny Asset Management L.P.	4,123,3654.1M	$14M	2.28%	ADD 32%
8	Casdin Capital, LLC	3,167,1753.2M	$11M	1.75%	—
9	Woodline Partners LP	3,003,3133.0M	$10M	1.66%	—
10	Sumitomo Mitsui Trust Group, Inc.	2,940,7932.9M	$10M	1.63%	TRIM -9%
11	Amova Asset Management Americas, Inc.	2,940,7932.9M	$10M	1.63%	TRIM -9%
12	UBS Group AG	2,888,4182.9M	$10M	1.60%	ADD 18%
13	GEODE CAPITAL MANAGEMENT, LLC	2,743,7002.7M	$10M	1.52%	ADD 4%
14	ADAR1 Capital Management, LLC	1,973,2822.0M	$7M	1.09%	NEW
15	FMR LLC	1,769,4761.8M	$6M	0.98%	TRIM -19%
16	Redmile Group, LLC	1,590,8321.6M	$6M	0.88%	NEW
17	TWO SIGMA INVESTMENTS, LP	1,572,8111.6M	$5M	0.87%	TRIM -3%
18	D. E. Shaw & Co., Inc.	1,393,6211.4M	$5M	0.77%	TRIM -10%
19	FARALLON CAPITAL MANAGEMENT LLC	1,240,8431.2M	$4M	0.69%	—
20	GOLDMAN SACHS GROUP INC	970,425970,425	$3M	0.54%	TRIM -45%
21	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	917,212917,212	$3M	0.51%	TRIM -2%
22	NORTHERN TRUST CORP	886,716886,716	$3M	0.49%	ADD 5%
23	VANGUARD PORTFOLIO MANAGEMENT LLC	862,204862,204	$3M	0.48%	NEW
24	JPMORGAN CHASE & CO	844,154844,154	$3M	0.47%	ADD 94%
25	Greenwich Wealth Management LLC	750,001750,001	$3M	0.42%	—
26	RENAISSANCE TECHNOLOGIES LLC	741,039741,039	$3M	0.41%	TRIM -36%
27	VANGUARD FIDUCIARY TRUST CO	717,002717,002	$2M	0.40%	NEW
28	SUSQUEHANNA INTERNATIONAL GROUP, LLP	715,829715,829	$2M	0.40%	TRIM -39%
29	MORGAN STANLEY	639,457639,457	$2M	0.35%	TRIM -45%
30	HRT FINANCIAL LP	612,769612,769	$2M	0.34%	TRIM -6%
31	BANK OF AMERICA CORP /DE/	577,004577,004	$2M	0.32%	TRIM -11%
32	AQR CAPITAL MANAGEMENT LLC	554,935554,935	$2M	0.31%	ADD 33%
33	MOORE CAPITAL MANAGEMENT, LP	500,000500,000	$2M	0.28%	—
34	Alessandra Capital Management, LLC	425,510425,510	$1M	0.24%	NEW
35	Bollard Group LLC	361,136361,136	$1M	0.20%	—
36	HighTower Advisors, LLC	340,255340,255	$1M	0.19%	TRIM -15%
37	CITADEL ADVISORS LLC	336,358336,358	$1M	0.19%	ADD 198%
38	WELLS FARGO & COMPANY/MN	319,550319,550	$1M	0.18%	ADD 9%
39	DIMENSIONAL FUND ADVISORS LP	304,522304,522	$1M	0.17%	ADD 262%
40	WELLINGTON MANAGEMENT GROUP LLP	278,120278,120	$967,857	0.15%	ADD 12%
41	Nuveen, LLC	275,931275,931	$960,240	0.15%	ADD 10%
42	Bank of New York Mellon Corp	267,219267,219	$929,922	0.15%	ADD 8%
43	CHELSEA COUNSEL CO	227,000227,000	$787,690	0.13%	—
44	Rafferty Asset Management, LLC	215,582215,582	$750,225	0.12%	ADD 15%
45	IQ EQ FUND MANAGEMENT (IRELAND) Ltd	205,389205,389	$714,754	0.11%	ADD 15%
46	Green Alpha Advisors, LLC	191,171191,171	$665,275	0.11%	—
47	Swiss National Bank	178,600178,600	$621,528	0.10%	ADD 5%
48	Keystone Financial Group	166,010166,010	$577,715	0.09%	ADD 28%
49	DEUTSCHE BANK AG\	157,440157,440	$547,891	0.09%	ADD 6%
50	XTX Topco Ltd	157,282157,282	$547,341	0.09%	ADD 116%
51	Elevate Capital Advisors, LLC	151,069151,069	$525,720	0.08%	ADD 254%
52	MARSHALL WACE, LLP	141,957141,957	$494,010	0.08%	NEW
53	BRIDGEWAY CAPITAL MANAGEMENT, LLC	134,800134,800	$469,104	0.07%	—
54	PRICE T ROWE ASSOCIATES INC /MD/	133,755133,755	$466,000	0.07%	ADD 28%
55	ALLIANCEBERNSTEIN L.P.	122,460122,460	$424,936	0.07%	ADD 13%
56	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	122,463122,463	$421,223	0.07%	ADD 6%
57	Steward Partners Investment Advisory, LLC	117,456117,456	$408,747	0.07%	—
58	FIL Ltd	115,206115,206	$400,917	0.06%	—
59	RHUMBLINE ADVISERS	114,269114,269	$397,649	0.06%	ADD 5%
60	Engineers Gate Manager LP	110,348110,348	$384,011	0.06%	ADD 82%
61	Palumbo Wealth Management LLC	102,246102,246	$355,817	0.06%	ADD 20%
62	Invesco Ltd.	96,87596,875	$337,125	0.05%	ADD 71%
63	PROFUND ADVISORS LLC	95,80695,806	$333,405	0.05%	ADD 38%
64	TD Asset Management Inc	94,14894,148	$327,635	0.05%	—
65	Squarepoint Ops LLC	94,06694,066	$327,350	0.05%	TRIM -57%
66	Rockefeller Capital Management L.P.	91,40191,401	$318,076	0.05%	TRIM -25%
67	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	86,47386,473	$300,926	0.05%	—
68	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	85,30085,300	$296,844	0.05%	TRIM -14%
69	Mariner, LLC	78,39878,398	$272,737	0.04%	ADD 116%
70	Concurrent Investment Advisors, LLC	74,17774,177	$258,136	0.04%	NEW
71	IEQ CAPITAL, LLC	74,01374,013	$257,565	0.04%	ADD 99%
72	Virtus Investment Advisers, LLC	66,50866,508	$231,448	0.04%	ADD 2%
73	LPL Financial LLC	66,42466,424	$231,156	0.04%	ADD 102%
74	Legal & General Group Plc	66,44466,444	$230,893	0.04%	TRIM -18%
75	Russell Investments Group, Ltd.	64,27364,273	$223,667	0.04%	ADD 841%
76	BARCLAYS PLC	63,77363,773	$221,931	0.04%	TRIM -82%
77	TUDOR INVESTMENT CORP ET AL	61,54661,546	$214,180	0.03%	NEW
78	JANUS HENDERSON GROUP PLC	60,90060,900	$211,628	0.03%	—
79	&PARTNERS	59,47059,470	$206,956	0.03%	—
80	VANGUARD ASSET MANAGEMENT, Ltd	59,02159,021	$205,393	0.03%	NEW
81	Aquatic Capital Management LLC	54,23054,230	$188,720	0.03%	NEW
82	LOS ANGELES CAPITAL MANAGEMENT LLC	52,61552,615	$183,100	0.03%	NEW
83	AMERIPRISE FINANCIAL INC	49,58449,584	$172,553	0.03%	TRIM -8%
84	CITIGROUP INC	47,23247,232	$164,368	0.03%	TRIM -8%
85	Quadrature Capital Ltd	46,89346,893	$163,188	0.03%	TRIM -11%
86	Mutual Advisors, LLC	45,20045,200	$157,296	0.03%	—
87	Vanguard Global Advisers, LLC	44,26944,269	$154,056	0.02%	NEW
88	MetLife Investment Management, LLC	44,20844,208	$153,844	0.02%	TRIM -23%
89	VARCOV Co.	41,96441,964	$146,035	0.02%	NEW
90	IvyRock Asset Management (HK) Ltd	41,80041,800	$145,464	0.02%	—
91	DRW Securities, LLC	40,96440,964	$142,554	0.02%	NEW
92	JONES FINANCIAL COMPANIES LLLP	40,30740,307	$136,238	0.02%	—
93	AXQ CAPITAL, LP	36,74236,742	$127,862	0.02%	ADD 10%
94	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	37,68137,681	$125,101	0.02%	ADD 44%
95	Kingsview Wealth Management, LLC	35,00035,000	$121,800	0.02%	ADD 133%
96	BNP PARIBAS FINANCIAL MARKETS	34,41334,413	$119,757	0.02%	ADD 250%
97	CWM, LLC	33,81133,811	$117,662	0.02%	ADD 33%
98	OPPENHEIMER & CO INC	33,65633,656	$117,123	0.02%	ADD 171%
99	Crestwood Advisors Group, LLC	32,37432,374	$112,661	0.02%	—
100	China Universal Asset Management Co., Ltd.	32,03332,033	$111,475	0.02%	ADD 9%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Alphabet Inc.

15.1M

16.6M

$58M

BlackRock, Inc.

4.5M

4.3M

4.5M

5.7M

8.3M

8.5M

$30M

STATE STREET CORP

1.2M

1.1M

1.2M

1.3M

5.1M

6.3M

$22M

ARK Investment Management LLC

5.2M

3.1M

2.3M

5.5M

5.4M

6.2M

$22M

T. Rowe Price Investment Management, Inc.

4.0M

4.1M

6.5M

9.2M

7.1M

5.5M

$19M

VANGUARD CAPITAL MANAGEMENT LLC

—

4.5M

$16M

Balyasny Asset Management L.P.

16K

—

48K

3.1M

4.1M

$14M

Casdin Capital, LLC

367K

1.6M

3.2M

$11M

Woodline Partners LP

—

3.0M

$10M

Sumitomo Mitsui Trust Group, Inc.

3.1M

2.9M

1.6M

3.6M

3.2M

2.9M

$10M

Amova Asset Management Americas, Inc.

3.1M

2.9M

1.6M

3.6M

3.2M

2.9M

$10M

UBS Group AG

218K

118K

195K

305K

2.4M

2.9M

$10M

GEODE CAPITAL MANAGEMENT, LLC

1.5M

1.8M

2.6M

2.7M

$10M

ADAR1 Capital Management, LLC

—

2.0M

$7M

FMR LLC

3.8M

3.7M

2.8M

2.2M

1.8M

$6M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	190	98,329,186	54.4%	$342M
2025-Q4	182	98,118,134	54.3%	$340M
2025-Q3	167	92,450,333	51.2%	$512M
2025-Q2	121	58,691,493	32.5%	$145M
2025-Q1	125	60,402,565	33.4%	$120M
2024-Q4	131	64,335,699	35.6%	$188M
2024-Q3	116	68,748,481	38.1%	$266M
2024-Q2	122	68,926,823	38.2%	$354M
2024-Q1	115	67,098,214	37.1%	$470M
2023-Q4	105	48,948,639	27.1%	$434M
2023-Q3	83	49,517,455	27.4%	$472M
2023-Q2	79	46,131,808	25.5%	$676M

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · PRME

Activists — 13D, active intent

ARCH Venture Fund XII, L.P.10.4%NEWSCHEDULE 13D/A · Amd 2 · event 2025-08-07SEC →

18,587,036 shares · 12 reporting persons

Large holders — 13G, passive (top 4 by % of class)

Holder

% of class

Type

As of

GV 2019, L.P.

12.3%

Passive

2025-09-30

SEC →

Newpath Partners, L.P.

4.7%

Exempt

2024-12-31

SEC →

FMR LLC

3.8%

Passive

2025-09-30

SEC →

T. Rowe Price Investment Management, Inc.

PRME US Equity☆

Institutional ownership· 13F filers holding PRME · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · PRME

Institutional ownership· 13F filers holding PRME · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · PRME

PRME US Equity