| 1 | 1TANG CAPITAL MANAGEMENT LLC | 6,143,1326.1M | $8M | 9.92% | — |
| 2 | 2CITADEL ADVISORS LLC | 3,226,5993.2M | $4M | 5.21% | ADD 25% |
| 3 | 3Blue Owl Capital Holdings LP | 2,969,1993.0M | $4M | 4.80% | — |
| 4 | 4ADAR1 Capital Management, LLC | 2,585,1262.6M | $3M | 4.17% | ADD 3402% |
| 5 | 5ACADIAN ASSET MANAGEMENT LLC | 2,416,5082.4M | $3M | 3.90% | ADD 2% |
| 6 | 6VANGUARD CAPITAL MANAGEMENT LLC | 2,343,1012.3M | $3M | 3.78% | NEW† |
| 7 | 7TWO SIGMA INVESTMENTS, LP | 2,253,1382.3M | $3M | 3.64% | ADD 136% |
| 8 | 8Monaco Asset Management SAM | 1,938,7471.9M | $2M | 3.13% | — |
| 9 | 9RENAISSANCE TECHNOLOGIES LLC | 1,852,8421.9M | $2M | 2.99% | ADD 77% |
| 10 | 10Prosight Management, LP | 1,667,6001.7M | $2M | 2.69% | ADD 7% |
| 11 | 11Woodline Partners LP | 1,666,8301.7M | $2M | 2.69% | TRIM -18% |
| 12 | 12BML Capital Management, LLC | 1,546,1371.5M | $2M | 2.50% | — |
| 13 | 13Peapod Lane Capital LLC | 1,288,5781.3M | $2M | 2.08% | ADD 45% |
| 14 | 14MILLENNIUM MANAGEMENT LLC | 1,180,5181.2M | $1M | 1.91% | ADD 189% |
| 15 | 15BlackRock, Inc. | 1,096,4301.1M | $1M | 1.77% | ADD 2% |
| 16 | 16UBS Group AG | 1,057,9541.1M | $1M | 1.71% | — |
| 17 | 17MARSHALL WACE, LLP | 995,973995,973 | $1M | 1.61% | TRIM -8% |
| 18 | 18Eversept Partners, LP | 891,425891,425 | $1M | 1.44% | ADD 6% |
| 19 | 19JPMORGAN CHASE & CO | 861,823861,823 | $1M | 1.39% | TRIM -29% |
| 20 | 20Redmile Group, LLC | 772,126772,126 | $972,879 | 1.25% | TRIM -52% |
| 21 | 21JACOBS LEVY EQUITY MANAGEMENT, INC | 718,543718,543 | $905,364 | 1.16% | ADD 29% |
| 22 | 22GOLDMAN SACHS GROUP INC | 596,837596,837 | $752,014 | 0.96% | ADD 116% |
| 23 | 23BRIDGEWAY CAPITAL MANAGEMENT, LLC | 553,630553,630 | $697,574 | 0.89% | ADD 72% |
| 24 | 24BESSEMER GROUP INC | 532,079532,079 | $670,000 | 0.86% | — |
| 25 | 25Connor, Clark & Lunn Investment Management Ltd. | 517,453517,453 | $651,991 | 0.84% | ADD 39% |
| 26 | 26MORGAN STANLEY | 505,739505,739 | $637,231 | 0.82% | TRIM -8% |
| 27 | 27XTX Topco Ltd | 500,838500,838 | $631,056 | 0.81% | TRIM -8% |
| 28 | 28DAFNA Capital Management LLC | 487,000487,000 | $613,620 | 0.79% | NEW |
| 29 | 29Centiva Capital, LP | 432,525432,525 | $544,982 | 0.70% | TRIM -57% |
| 30 | 30GEODE CAPITAL MANAGEMENT, LLC | 417,274417,274 | $526,154 | 0.67% | TRIM -30% |
| 31 | 31Laurion Capital Management LP | 412,796412,796 | $520,123 | 0.67% | ADD 60% |
| 32 | 32GSA CAPITAL PARTNERS LLP | 402,092402,092 | $507,000 | 0.65% | TRIM -36% |
| 33 | 33JANE STREET GROUP, LLC | 356,794356,794 | $449,561 | 0.58% | TRIM -45% |
| 34 | 34BANK OF AMERICA CORP /DE/ | 352,708352,708 | $444,412 | 0.57% | TRIM -50% |
| 35 | 35TORNO CAPITAL, LLC | 350,000350,000 | $441,000 | 0.57% | ADD 9% |
| 36 | 36VANGUARD FIDUCIARY TRUST CO | 339,540339,540 | $427,820 | 0.55% | NEW |
| 37 | 37SEI INVESTMENTS CO | 297,291297,291 | $374,583 | 0.48% | — |
| 38 | 38ArrowMark Colorado Holdings LLC | 281,189281,189 | $354,298 | 0.45% | — |
| 39 | 39NANO CAP NEW MILLENNIUM GROWTH FUND L P | 275,000275,000 | $346,500 | 0.44% | ADD 17% |
| 40 | 40STATE STREET CORP | 253,418253,418 | $319,307 | 0.41% | — |
| 41 | 41Rangeley Capital, LLC | 225,000225,000 | $283,500 | 0.36% | — |
| 42 | 42Stonepine Capital Management, LLC | 224,650224,650 | $283,059 | 0.36% | TRIM -2% |
| 43 | 43HighMark Wealth Management LLC | 166,224166,224 | $209,442 | 0.27% | TRIM -3% |
| 44 | 44Squarepoint Ops LLC | 163,215163,215 | $205,651 | 0.26% | ADD 65% |
| 45 | 45NORTHERN TRUST CORP | 154,176154,176 | $194,263 | 0.25% | ADD 25% |
| 46 | 46VANGUARD PORTFOLIO MANAGEMENT LLC | 153,810153,810 | $193,801 | 0.25% | NEW |
| 47 | 47Invesco Ltd. | 115,218115,218 | $145,175 | 0.19% | — |
| 48 | 48OSAIC HOLDINGS, INC. | 114,924114,924 | $144,804 | 0.19% | — |
| 49 | 49Hennion & Walsh Asset Management, Inc. | 106,705106,705 | $134,448 | 0.17% | TRIM -6% |
| 50 | 50Bond & Devick Financial Network, Inc. | 100,160100,160 | $126,202 | 0.16% | — |
| 51 | 51DIMENSIONAL FUND ADVISORS LP | 99,77399,773 | $125,396 | 0.16% | TRIM -18% |
| 52 | 52Verdad Advisers, LP | 98,32098,320 | $123,883 | 0.16% | NEW |
| 53 | 53ALGERT GLOBAL LLC | 84,45284,452 | $106,000 | 0.14% | — |
| 54 | 54FEDERATED HERMES, INC. | 62,65162,651 | $78,940 | 0.10% | ADD 5% |
| 55 | 55AMERIPRISE FINANCIAL INC | 55,12955,129 | $69,463 | 0.09% | NEW |
| 56 | 56SUSQUEHANNA INTERNATIONAL GROUP, LLP | 52,95652,956 | $66,725 | 0.09% | ADD 55% |
| 57 | 57Quadrature Capital Ltd | 50,98150,981 | $64,236 | 0.08% | TRIM -48% |
| 58 | 58SIMPLEX TRADING, LLC | 48,05448,054 | $60,548 | 0.08% | ADD 5% |
| 59 | 59Point72 Asset Management, L.P. | 47,05447,054 | $59,288 | 0.08% | — |
| 60 | 60TUDOR INVESTMENT CORP ET AL | 29,72929,729 | $37,459 | 0.05% | — |
| 61 | 61PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 28,50028,500 | $35,910 | 0.05% | NEW |
| 62 | 62Blackstone Inc. | 22,20622,206 | $27,980 | 0.04% | — |
| 63 | 63Vanguard Global Advisers, LLC | 19,50719,507 | $24,579 | 0.03% | NEW |
| 64 | 64Bronte Capital Management Pty Ltd. | 18,61318,613 | $23,452 | 0.03% | — |
| 65 | 65Universal- Beteiligungs- und Servicegesellschaft mbH | 18,06518,065 | $22,762 | 0.03% | — |
| 66 | 66Bank of New York Mellon Corp | 15,82415,824 | $19,938 | 0.03% | — |
| 67 | 67SG Americas Securities, LLC | 12,60412,604 | $16,000 | 0.02% | ADD 3% |
| 68 | 68Fiduciary Trust Co | 11,62011,620 | $14,641 | 0.02% | — |
| 69 | 69HRT FINANCIAL LP | 11,19611,196 | $14,000 | 0.02% | TRIM -65% |
| 70 | 70Qube Research & Technologies Ltd | 10,96610,966 | $13,817 | 0.02% | TRIM -29% |
| 71 | 71Vanguard Personalized Indexing Management, LLC | 10,02910,029 | $12,637 | 0.02% | TRIM -62% |
| 72 | 72Tower Research Capital LLC (TRC) | 3,3153,315 | $4,177 | 0.01% | NEW |
| 73 | 73RHUMBLINE ADVISERS | 2,3792,379 | $2,997 | 0.00% | — |
| 74 | 74Owl Creek Wealth Partners LLC | 2,3002,300 | $2,898 | 0.00% | NEW |
| 75 | 75ROYAL BANK OF CANADA | 997997 | $2,000 | 0.00% | TRIM -16% |
| 76 | 76Rockefeller Capital Management L.P. | 660660 | $832 | 0.00% | — |
| 77 | 77BNP PARIBAS FINANCIAL MARKETS | 657657 | $828 | 0.00% | — |
| 78 | 78FMR LLC | 524524 | $660 | 0.00% | TRIM -73% |
| 79 | 79HARBOUR INVESTMENTS, INC. | 488488 | $615 | 0.00% | NEW |
| 80 | 80MAI Capital Management | 400400 | $504 | 0.00% | — |
| 81 | 81SBI Securities Co., Ltd. | 300300 | $378 | 0.00% | TRIM -6% |
| 82 | 82CWM, LLC | 212212 | $267 | 0.00% | TRIM -46% |
| 83 | 83NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 100100 | $126 | 0.00% | NEW |
| 84 | 84WELLS FARGO & COMPANY/MN | 5050 | $63 | 0.00% | — |
| 85 | 85Truvestments Capital LLC | 5050 | $63 | 0.00% | — |
| 86 | 86Zurcher Kantonalbank (Zurich Cantonalbank) | 3636 | $45 | 0.00% | — |
| 87 | 87BARCLAYS PLC | 3434 | $43 | 0.00% | TRIM -100% |
| 88 | 88Farther Finance Advisors, LLC | 55 | $7 | 0.00% | — |
| 89 | 89FIFTH THIRD BANCORP | 44 | $5 | 0.00% | NEW |
| 90 | 90Caitong International Asset Management Co., Ltd | 44 | $5 | 0.00% | ADD 300% |
| 91 | 91Capital Advisors, Ltd. LLC | 2020 | $0 | 0.00% | NEW |
