Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-05-08 | Azoulay Salomon | Officer | +Exercise | 55,000 | $10.46 | $575,300 |
| 2026-05-08 | Azoulay Salomon | Officer | −Sell | 15,003 | $38.30 | $574,615 |
| 2026-05-08 | Azoulay Salomon | Officer | +Exercise | 15,003 | $16.00 | $240,048 |
| 2026-05-08 | Azoulay Salomon | Officer | −Sell | 55,000 | $38.38 | $2M |
| 2026-05-06 | Hawryluk P. Kent | Director,Officer | −Sell | 607 | $29.54 | $17,931 |
| 2026-05-06 | Azoulay Salomon | Officer | −Sell | 231 | $29.54 | $6,824 |
| 2026-05-01 | Hoerter Steven L. | Director | +Grant | 11,938 | — | — |
| 2026-03-13 | Hawryluk P. Kent | Director,Officer | +Buy | 18,500 | $28.41 | $525,585 |
| 2026-02-26 | Hawryluk P. Kent | Director,Officer | +Exercise | 28,768 | $16.00 | $460,288 |
| 2026-02-02 | Hawryluk P. Kent | Director,Officer | +Grant | 35,250 | — | — |
| 2026-02-02 | Bartram Richard | Officer | +Grant | 15,000 | — | — |
| 2026-02-02 | Azoulay Salomon | Officer | +Grant | 15,000 | — | — |
| 2025-10-24 | Hawryluk P. Kent | Director,Officer | +Exercise | 182,859 | $3.25 | $594,292 |
| 2025-10-20 | Hawryluk P. Kent | Director,Officer | +Buy | 20,000 | $13.64 | $272,800 |
| 2025-10-17 | Hoerter Steven L. | Director | +Buy | 20,000 | $13.25 | $265,000 |
| 2025-09-26 | FHMLS X, L.P. | TenPercentOwner | +Buy | 666,666 | $18.00 | $12M |
| 2025-04-08 | Pescovitz Ora H. | Director | +Buy | 7,693 | $5.89 | $45,312 |
| 2025-02-18 | OrbiMed Genesis GP LLC | Director,TenPercentOwner | +Buy | 49,070 | $10.84 | $531,919 |
| 2025-02-18 | OrbiMed Genesis GP LLC | Director,TenPercentOwner | +Buy | 94,100 | $10.84 | $1M |
| 2025-02-18 | GORDON CARL L | Director,TenPercentOwner | +Buy | 94,100 | $10.84 | $1M |
| 2025-02-18 | GORDON CARL L | Director,TenPercentOwner | +Buy | 49,070 | $10.84 | $531,919 |
| 2025-02-14 | OrbiMed Genesis GP LLC | Director,TenPercentOwner | +Buy | 29,540 | $9.85 | $290,969 |
| 2025-02-14 | OrbiMed Genesis GP LLC | Director,TenPercentOwner | +Buy | 17,962 | $9.90 | $177,824 |
| 2025-02-14 | GORDON CARL L | Director,TenPercentOwner | +Buy | 17,962 | $9.90 | $177,824 |
| 2025-02-14 | GORDON CARL L | Director,TenPercentOwner | +Buy | 29,540 | $9.85 | $290,969 |
| 2025-02-04 | Hawryluk P. Kent | Director,Officer | +Buy | 50,000 | $10.69 | $534,500 |
| 2024-09-16 | Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | TenPercentOwner | +Conversion | 403,787 | — | — |
| 2024-09-16 | Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | TenPercentOwner | +Conversion | 1,386,335 | — | — |
| 2024-09-16 | GORDON CARL L | Director,TenPercentOwner | +Conversion | 403,787 | — | — |
| 2024-09-16 | GORDON CARL L | Director,TenPercentOwner | +Conversion | 2,658,428 | — | — |
| 2024-09-16 | GORDON CARL L | Director,TenPercentOwner | +Buy | 250,000 | $16.00 | $4M |
| 2024-09-16 | GORDON CARL L | Director,TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Aynechi Tiba | Director | +Conversion | 1,386,335 | — | — |
| 2024-09-16 | Aynechi Tiba | Director | +Buy | 750,000 | $16.00 | $12M |
| 2024-09-16 | Hawryluk P. Kent | Director,Officer | +Conversion | 115,914 | — | — |
| 2024-09-16 | Hawryluk P. Kent | Director,Officer | +Conversion | 283,846 | — | — |
| 2024-09-16 | Heron Patrick J | Director,TenPercentOwner | +Conversion | 3,927,774 | — | — |
| 2024-09-16 | Heron Patrick J | Director,TenPercentOwner | +Buy | 625,000 | $16.00 | $10M |
| 2024-09-16 | CORNELIUS JAMES M | Director | +Conversion | 102,082 | — | — |
| 2024-09-16 | FHMLS X, L.P. | TenPercentOwner | +Buy | 625,000 | $16.00 | $10M |
| 2024-09-16 | FHMLS X, L.P. | TenPercentOwner | +Conversion | 3,927,774 | — | — |
| 2024-09-16 | NEA Partners 17, L.P. | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | NEA Partners 17, L.P. | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | NEA Partners 17, L.P. | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | ORBIMED ADVISORS LLC | Director,TenPercentOwner | +Buy | 250,000 | $16.00 | $4M |
| 2024-09-16 | ORBIMED ADVISORS LLC | Director,TenPercentOwner | +Conversion | 403,787 | — | — |
| 2024-09-16 | ORBIMED ADVISORS LLC | Director,TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | ORBIMED ADVISORS LLC | Director,TenPercentOwner | +Conversion | 2,658,428 | — | — |
| 2024-09-16 | SANDELL SCOTT D | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | SANDELL SCOTT D | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | SANDELL SCOTT D | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Yang Rick | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | Yang Rick | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Yang Rick | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Walker Paul Edward | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | Walker Paul Edward | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Walker Paul Edward | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Makhzoumi Mohamad | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | Makhzoumi Mohamad | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Makhzoumi Mohamad | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Florence Anthony A. Jr. | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | Florence Anthony A. Jr. | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Florence Anthony A. Jr. | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Chang Carmen | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Chang Carmen | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | Chang Carmen | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Behbahani Ali | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | Behbahani Ali | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Behbahani Ali | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | BASKETT FOREST | TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | BASKETT FOREST | TenPercentOwner | +Conversion | 1,023,103 | — | — |
| 2024-09-16 | BASKETT FOREST | TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Mathers Edward T | Director,TenPercentOwner | +Buy | 500,000 | $16.00 | $8M |
| 2024-09-16 | Mathers Edward T | Director,TenPercentOwner | +Conversion | 2,091,383 | — | — |
| 2024-09-16 | Mathers Edward T | Director,TenPercentOwner | +Conversion | 1,023,103 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.