| 1 | 1PRIMECAP MANAGEMENT CO/CA/ | 4,724,9914.7M | $6M | 11.19% | — |
| 2 | 2MORGAN STANLEY | 3,993,5624.0M | $5M | 9.46% | TRIM -4% |
| 3 | 3Soleus Capital Management, L.P. | 2,788,3232.8M | $4M | 6.60% | ADD 37% |
| 4 | 4BlackRock, Inc. | 2,661,6072.7M | $3M | 6.30% | — |
| 5 | 5ExodusPoint Capital Management, LP | 1,943,8341.9M | $3M | 4.60% | — |
| 6 | 6VANGUARD CAPITAL MANAGEMENT LLC | 1,634,2641.6M | $2M | 3.87% | NEW† |
| 7 | 7BANK OF AMERICA CORP /DE/ | 1,166,8261.2M | $2M | 2.76% | ADD 60% |
| 8 | 8DEUTSCHE BANK AG\ | 1,163,6781.2M | $2M | 2.76% | ADD 3% |
| 9 | 9GEODE CAPITAL MANAGEMENT, LLC | 944,492944,492 | $1M | 2.24% | ADD 4% |
| 10 | 10STATE STREET CORP | 809,116809,116 | $1M | 1.92% | — |
| 11 | 11Stonepine Capital Management, LLC | 768,288768,288 | $991,092 | 1.82% | ADD 58% |
| 12 | 12Parkman Healthcare Partners LLC | 755,636755,636 | $974,770 | 1.79% | ADD 4% |
| 13 | 13BRAIDWELL LP | 752,541752,541 | $970,778 | 1.78% | — |
| 14 | 14BARCLAYS PLC | 683,435683,435 | $881,632 | 1.62% | ADD 45% |
| 15 | 15VANGUARD PORTFOLIO MANAGEMENT LLC | 604,455604,455 | $779,747 | 1.43% | NEW |
| 16 | 16ADAR1 Capital Management, LLC | 374,497374,497 | $483,101 | 0.89% | ADD 5% |
| 17 | 17AQR CAPITAL MANAGEMENT LLC | 357,578357,578 | $461,276 | 0.85% | ADD 507% |
| 18 | 18JPMORGAN CHASE & CO | 388,103388,103 | $457,962 | 0.92% | TRIM -9% |
| 19 | 19NORTHERN TRUST CORP | 354,674354,674 | $457,529 | 0.84% | ADD 5% |
| 20 | 20D. E. Shaw & Co., Inc. | 335,074335,074 | $432,246 | 0.79% | TRIM -40% |
| 21 | 21RENAISSANCE TECHNOLOGIES LLC | 320,300320,300 | $413,187 | 0.76% | ADD 10% |
| 22 | 22Jefferies Financial Group Inc. | 285,110285,110 | $367,792 | 0.68% | — |
| 23 | 23VANGUARD FIDUCIARY TRUST CO | 281,248281,248 | $362,810 | 0.67% | NEW |
| 24 | 24CFM WEALTH PARTNERS LLC | 264,039264,039 | $340,610 | 0.63% | — |
| 25 | 25Birchview Capital, LP | 250,221250,221 | $322,785 | 0.59% | — |
| 26 | 26GOLDMAN SACHS GROUP INC | 223,450223,450 | $288,251 | 0.53% | TRIM -39% |
| 27 | 27UBS Group AG | 209,701209,701 | $270,514 | 0.50% | ADD 22% |
| 28 | 28ACADIAN ASSET MANAGEMENT LLC | 166,341166,341 | $212,000 | 0.39% | TRIM -7% |
| 29 | 29NANO CAP NEW MILLENNIUM GROWTH FUND L P | 157,500157,500 | $203,175 | 0.37% | ADD 85% |
| 30 | 30Centiva Capital, LP | 153,882153,882 | $198,508 | 0.36% | ADD 730% |
| 31 | 31DIMENSIONAL FUND ADVISORS LP | 141,920141,920 | $182,656 | 0.34% | TRIM -16% |
| 32 | 32GSA CAPITAL PARTNERS LLP | 137,488137,488 | $177,000 | 0.33% | TRIM -66% |
| 33 | 33JANE STREET GROUP, LLC | 133,270133,270 | $171,918 | 0.32% | TRIM -19% |
| 34 | 34WESTFIELD CAPITAL MANAGEMENT CO LP | 110,000110,000 | $141,900 | 0.26% | TRIM -41% |
| 35 | 35Bank of New York Mellon Corp | 92,72092,720 | $119,609 | 0.22% | — |
| 36 | 36ALLIANCEBERNSTEIN L.P. | 52,20052,200 | $115,362 | 0.12% | — |
| 37 | 37SUSQUEHANNA INTERNATIONAL GROUP, LLP | 89,06989,069 | $114,899 | 0.21% | TRIM -53% |
| 38 | 38ALGERT GLOBAL LLC | 85,36285,362 | $110,000 | 0.20% | TRIM -14% |
| 39 | 39Squarepoint Ops LLC | 82,49282,492 | $106,415 | 0.20% | ADD 100% |
| 40 | 40XTX Topco Ltd | 80,08180,081 | $103,304 | 0.19% | TRIM -28% |
| 41 | 41CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 71,31971,319 | $92,002 | 0.17% | TRIM -23% |
| 42 | 42Nuveen, LLC | 69,10869,108 | $89,150 | 0.16% | — |
| 43 | 43TWO SIGMA INVESTMENTS, LP | 68,61268,612 | $88,509 | 0.16% | TRIM -48% |
| 44 | 44BRIDGEWAY CAPITAL MANAGEMENT, LLC | 61,00061,000 | $78,690 | 0.14% | TRIM -7% |
| 45 | 45CITADEL ADVISORS LLC | 57,00957,009 | $73,542 | 0.13% | ADD 26% |
| 46 | 46Engineers Gate Manager LP | 56,15156,151 | $72,435 | 0.13% | ADD 17% |
| 47 | 47Berger Financial Group, Inc | 54,00054,000 | $69,660 | 0.13% | NEW |
| 48 | 48Schonfeld Strategic Advisors LLC | 49,78849,788 | $64,225 | 0.12% | TRIM -59% |
| 49 | 49MERCER GLOBAL ADVISORS INC /ADV | 48,76748,767 | $62,909 | 0.12% | ADD 18% |
| 50 | 50FMR LLC | 48,22248,222 | $62,207 | 0.11% | TRIM -36% |
| 51 | 51RHUMBLINE ADVISERS | 46,38046,380 | $59,823 | 0.11% | TRIM -18% |
| 52 | 52PERKINS CAPITAL MANAGEMENT INC | 41,00041,000 | $52,890 | 0.10% | TRIM -16% |
| 53 | 53FJARDE AP-FONDEN /FOURTH SWEDISH NATIONAL PENSION FUND | 40,00040,000 | $51,600 | 0.09% | — |
| 54 | 54NINE MASTS CAPITAL Ltd | 38,59838,598 | $49,791 | 0.09% | ADD 282% |
| 55 | 55Susquehanna Portfolio Strategies, LLC | 37,77737,777 | $48,732 | 0.09% | TRIM -37% |
| 56 | 56JACOBS LEVY EQUITY MANAGEMENT, INC | 37,08137,081 | $47,834 | 0.09% | TRIM -79% |
| 57 | 57Redhawk Wealth Advisors, Inc. | 34,70034,700 | $44,763 | 0.08% | NEW |
| 58 | 58Cerity Partners LLC | 28,83628,836 | $37,199 | 0.07% | ADD 133% |
| 59 | 59SEI INVESTMENTS CO | 24,30324,303 | $31,351 | 0.06% | NEW |
| 60 | 60Creative Planning | 22,73122,731 | $29,323 | 0.05% | ADD 19% |
| 61 | 61IEQ CAPITAL, LLC | 21,58721,587 | $27,847 | 0.05% | NEW |
| 62 | 62PRICE T ROWE ASSOCIATES INC /MD/ | 19,88419,884 | $26,000 | 0.05% | — |
| 63 | 63R Squared Ltd | 19,78019,780 | $25,516 | 0.05% | NEW |
| 64 | 64WELLS FARGO & COMPANY/MN | 18,75018,750 | $24,188 | 0.04% | TRIM -61% |
| 65 | 65MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 18,35518,355 | $23,678 | 0.04% | ADD 2% |
| 66 | 66CWM, LLC | 17,71917,719 | $22,858 | 0.04% | ADD 363% |
| 67 | 6749 WEALTH MANAGEMENT, LLC | 15,18415,184 | $19,587 | 0.04% | ADD 28% |
| 68 | 68HSBC HOLDINGS PLC | 14,09014,090 | $18,458 | 0.03% | TRIM -39% |
| 69 | 69LAZARD ASSET MANAGEMENT LLC | 14,15614,156 | $18,261 | 0.03% | — |
| 70 | 70Vanguard Global Advisers, LLC | 13,55913,559 | $17,491 | 0.03% | NEW |
| 71 | 71Tower Research Capital LLC (TRC) | 11,40211,402 | $14,709 | 0.03% | ADD 143% |
| 72 | 72Mariner, LLC | 11,06711,067 | $14,275 | 0.03% | NEW |
| 73 | 73TUDOR INVESTMENT CORP ET AL | 11,02811,028 | $14,226 | 0.03% | TRIM -52% |
| 74 | 74Invesco Ltd. | 10,31810,318 | $13,310 | 0.02% | TRIM -2% |
| 75 | 75INTECH INVESTMENT MANAGEMENT LLC | 10,10510,105 | $13,035 | 0.02% | TRIM -21% |
| 76 | 76BNP PARIBAS FINANCIAL MARKETS | 8,0858,085 | $10,430 | 0.02% | TRIM -9% |
| 77 | 77Police & Firemen's Retirement System of New Jersey | 7,8107,810 | $10,075 | 0.02% | — |
| 78 | 78NEW YORK STATE COMMON RETIREMENT FUND | 6,9146,914 | $8,919 | 0.02% | — |
| 79 | 79EverSource Wealth Advisors, LLC | 4,8254,825 | $6,225 | 0.01% | ADD 480% |
| 80 | 80SIMPLEX TRADING, LLC | 4,0644,064 | $5,242 | 0.01% | TRIM -88% |
| 81 | 81Russell Investments Group, Ltd. | 3,8923,892 | $5,020 | 0.01% | TRIM -69% |
| 82 | 82ROYAL BANK OF CANADA | 4,0474,047 | $5,000 | 0.01% | ADD 280% |
| 83 | 83Ameritas Investment Partners, Inc. | 3,6173,617 | $4,666 | 0.01% | — |
| 84 | 84Optiver Holding B.V. | 3,3663,366 | $4,342 | 0.01% | TRIM -7% |
| 85 | 85Legal & General Group Plc | 3,1663,166 | $4,068 | 0.01% | TRIM -12% |
| 86 | 86PNC FINANCIAL SERVICES GROUP, INC. | 3,0043,004 | $3,876 | 0.01% | ADD 4318% |
| 87 | 87CITIGROUP INC | 2,8572,857 | $3,685 | 0.01% | ADD 227% |
| 88 | 88GAMMA Investing LLC | 2,8032,803 | $3,616 | 0.01% | ADD 33% |
| 89 | 89FEDERATED HERMES, INC. | 1,6291,629 | $2,101 | 0.00% | NEW |
| 90 | 90OSAIC HOLDINGS, INC. | 1,4451,445 | $1,863 | 0.00% | — |
| 91 | 91AdvisorNet Financial, Inc | 1,0001,000 | $1,290 | 0.00% | — |
| 92 | 92Physician Wealth Advisors, Inc. | 855855 | $1,103 | 0.00% | NEW |
| 93 | 93Allworth Financial LP | 491491 | $634 | 0.00% | ADD 2484% |
| 94 | 94NISA INVESTMENT ADVISORS, LLC | 465465 | $600 | 0.00% | ADD 117% |
| 95 | 95Parallel Advisors, LLC | 336336 | $433 | 0.00% | — |
| 96 | 96Farther Finance Advisors, LLC | 309309 | $396 | 0.00% | ADD 225% |
| 97 | 97Essential Partners LLC | 258258 | $333 | 0.00% | ADD 1333% |
| 98 | 98Sterling Capital Management LLC | 248248 | $320 | 0.00% | — |
| 99 | 99True Wealth Design, LLC | 165165 | $213 | 0.00% | NEW |
| 100 | 100IFP Advisors, Inc | 158158 | $204 | 0.00% | ADD 119% |
